CR10295A - "formulacion de un anticuerpo monoclonal humano anti-igf-1r" - Google Patents
"formulacion de un anticuerpo monoclonal humano anti-igf-1r"Info
- Publication number
- CR10295A CR10295A CR10295A CR10295A CR10295A CR 10295 A CR10295 A CR 10295A CR 10295 A CR10295 A CR 10295A CR 10295 A CR10295 A CR 10295A CR 10295 A CR10295 A CR 10295A
- Authority
- CR
- Costa Rica
- Prior art keywords
- igf
- formulation
- monoclonal antibody
- human monoclonal
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06111848 | 2006-03-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10295A true CR10295A (es) | 2008-10-06 |
Family
ID=37025222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10295A CR10295A (es) | 2006-03-28 | 2008-09-17 | "formulacion de un anticuerpo monoclonal humano anti-igf-1r" |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1998806A1 (fr) |
JP (1) | JP2009531371A (fr) |
KR (1) | KR20080104160A (fr) |
CN (1) | CN101410137A (fr) |
AR (1) | AR060130A1 (fr) |
AU (1) | AU2007229554A1 (fr) |
BR (1) | BRPI0709229A2 (fr) |
CA (1) | CA2647111A1 (fr) |
CL (1) | CL2007000797A1 (fr) |
CR (1) | CR10295A (fr) |
EC (1) | ECSP088778A (fr) |
IL (1) | IL193904A0 (fr) |
MA (1) | MA30345B1 (fr) |
MX (1) | MX2008012295A (fr) |
NO (1) | NO20083895L (fr) |
RU (1) | RU2008142359A (fr) |
TW (1) | TW200815029A (fr) |
WO (1) | WO2007110339A1 (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20081477A1 (es) * | 2006-12-11 | 2008-10-18 | Hoffmann La Roche | Formulacion liofilizada mab abeta |
GB0702888D0 (en) * | 2007-02-14 | 2007-03-28 | Glaxo Group Ltd | Novel Antibodies |
BRPI0809112A2 (pt) * | 2007-03-22 | 2014-08-26 | Imclone Llc | Formulações estáveis de anticorpos |
CN101687038A (zh) * | 2007-07-10 | 2010-03-31 | 霍夫曼-拉罗奇有限公司 | 新型制剂 |
CA2706403A1 (fr) * | 2007-11-29 | 2009-06-04 | F. Hoffmann-La Roche Ag | Agregats d'immunoglobulines |
RS53551B1 (en) * | 2007-12-21 | 2015-02-27 | F. Hoffmann La Roche Ag | ANTIBODY FORMULATION |
WO2010069858A1 (fr) * | 2008-12-19 | 2010-06-24 | F. Hoffmann-La Roche Ag | Composition pharmaceutique |
US20100316639A1 (en) | 2009-06-16 | 2010-12-16 | Genentech, Inc. | Biomarkers for igf-1r inhibitor therapy |
US9345661B2 (en) | 2009-07-31 | 2016-05-24 | Genentech, Inc. | Subcutaneous anti-HER2 antibody formulations and uses thereof |
AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
WO2011080209A2 (fr) * | 2009-12-29 | 2011-07-07 | F. Hoffmann-La Roche Ag | Nouvelle formation d'anticorps |
WO2011147921A1 (fr) * | 2010-05-28 | 2011-12-01 | Novo Nordisk A/S | Compositions stables multi-doses comprenant un anticorps et un agent conservateur |
HUE039209T2 (hu) | 2011-03-31 | 2018-12-28 | Merck Sharp & Dohme | Antitestek stabil formulációi emberi programozott halálreceptor PD-1 ellen és ezzel kapcsolatos kezelések |
CN102363040B (zh) * | 2011-10-21 | 2013-05-01 | 北京锐瑟科技有限公司 | 用于粘膜组织的抗微生物肽制剂 |
UA118029C2 (uk) | 2013-04-29 | 2018-11-12 | Ф. Хоффманн-Ля Рош Аг | Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування |
CN103505729B (zh) * | 2013-05-24 | 2015-10-28 | 华北制药集团新药研究开发有限责任公司 | 一种稳定的狂犬病毒人源抗体组合制剂 |
CN104707146B (zh) * | 2013-12-16 | 2019-04-16 | 浙江海正药业股份有限公司 | 一种含有阿达木单抗的药物组合物 |
EP3094648A1 (fr) | 2014-01-15 | 2016-11-23 | F. Hoffmann-La Roche AG | Variants de région fc présentant une liaison améliorée à la protéine a |
EP3148568A4 (fr) * | 2014-05-28 | 2018-01-17 | Nono Inc. | Formulation lyophilisée de tat-nr2b9c avec capteur d'acétylation |
AR102198A1 (es) | 2014-10-09 | 2017-02-08 | Regeneron Pharma | Proceso para reducir partículas subvisibles en una formulación farmacéutica |
CA2985718A1 (fr) | 2015-06-24 | 2016-12-29 | F. Hoffmann-La Roche Ag | Anticorps anti-recepteur de la transferrine avec une affinite adaptee |
RU2731418C2 (ru) * | 2015-09-28 | 2020-09-02 | Сучжоу Санкадия Биофармасьютикалз Ко., Лтд. | Стабильный фармацевтический препарат на основе антитела к pd-1 и его применение в медицине |
PE20231655A1 (es) | 2015-10-02 | 2023-10-17 | Hoffmann La Roche | Anticuerpos biespecificos contra el cd20 humano y el receptor de transferrina humano y metodos de uso |
AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
CN106199007B (zh) * | 2016-08-03 | 2017-04-05 | 烟台普罗吉生物科技发展有限公司 | 蛋白保护剂 |
AU2017312785A1 (en) | 2016-08-16 | 2019-01-24 | Regeneron Pharmaceuticals, Inc. | Methods for quantitating individual antibodies from a mixture |
EP4071469A3 (fr) | 2016-10-25 | 2022-12-14 | Regeneron Pharmaceuticals, Inc. | Procédés et systèmes d'analyse de données de chromatographie |
JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
CN110913906A (zh) | 2017-05-02 | 2020-03-24 | 默沙东公司 | 抗lag3抗体的制剂和抗lag3抗体与抗pd-1抗体的共制剂 |
CA3073935A1 (fr) | 2017-09-19 | 2019-03-28 | Regeneron Pharmaceuticals, Inc. | Procedes de reduction de la formation de particules et compositions formees par ceux-ci |
EA202190163A1 (ru) | 2018-07-02 | 2021-03-30 | Ридженерон Фармасьютикалз, Инк. | Системы и способы получения полипептида из смеси |
CN114324882B (zh) * | 2020-10-12 | 2022-12-27 | 广东菲鹏生物有限公司 | 蛋白稳定剂及其应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU740284B2 (en) * | 1997-06-13 | 2001-11-01 | Genentech Inc. | Stabilized antibody formulation |
PE20020801A1 (es) * | 2001-01-05 | 2002-09-06 | Pfizer | Anticuerpos contra el receptor del factor de crecimiento similar a insulina |
MXPA04000747A (es) * | 2001-07-25 | 2004-07-08 | Protein Desing Labs Inc | Formulacion farmaceutica liofilizada estable de anticuerpos igg. |
US7378503B2 (en) * | 2003-04-02 | 2008-05-27 | Hoffmann-La Roche Inc. | Antibodies against insulin-like growth factor 1 receptor and uses thereof |
AU2004229335C1 (en) * | 2003-04-04 | 2010-06-17 | Genentech, Inc. | High concentration antibody and protein formulations |
US7579157B2 (en) * | 2003-07-10 | 2009-08-25 | Hoffmann-La Roche Inc. | Antibody selection method against IGF-IR |
KR100825156B1 (ko) * | 2003-08-13 | 2008-04-24 | 화이자 프로덕츠 인코포레이티드 | 변형된 인간 igf-ir 항체 |
-
2007
- 2007-03-19 WO PCT/EP2007/052569 patent/WO2007110339A1/fr active Application Filing
- 2007-03-19 MX MX2008012295A patent/MX2008012295A/es active IP Right Grant
- 2007-03-19 RU RU2008142359/15A patent/RU2008142359A/ru not_active Application Discontinuation
- 2007-03-19 BR BRPI0709229-6A patent/BRPI0709229A2/pt not_active IP Right Cessation
- 2007-03-19 JP JP2009502016A patent/JP2009531371A/ja active Pending
- 2007-03-19 AU AU2007229554A patent/AU2007229554A1/en not_active Abandoned
- 2007-03-19 KR KR1020087023673A patent/KR20080104160A/ko not_active Application Discontinuation
- 2007-03-19 CN CNA2007800114320A patent/CN101410137A/zh active Pending
- 2007-03-19 EP EP07727047A patent/EP1998806A1/fr not_active Withdrawn
- 2007-03-19 CA CA002647111A patent/CA2647111A1/fr not_active Abandoned
- 2007-03-26 AR ARP070101241A patent/AR060130A1/es not_active Application Discontinuation
- 2007-03-26 TW TW096110388A patent/TW200815029A/zh unknown
- 2007-03-26 CL CL2007000797A patent/CL2007000797A1/es unknown
-
2008
- 2008-09-04 IL IL193904A patent/IL193904A0/en unknown
- 2008-09-11 NO NO20083895A patent/NO20083895L/no not_active Application Discontinuation
- 2008-09-17 CR CR10295A patent/CR10295A/es not_active Application Discontinuation
- 2008-09-26 EC EC2008008778A patent/ECSP088778A/es unknown
- 2008-10-20 MA MA31308A patent/MA30345B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
EP1998806A1 (fr) | 2008-12-10 |
TW200815029A (en) | 2008-04-01 |
WO2007110339A1 (fr) | 2007-10-04 |
AR060130A1 (es) | 2008-05-28 |
IL193904A0 (en) | 2011-08-01 |
JP2009531371A (ja) | 2009-09-03 |
RU2008142359A (ru) | 2010-05-10 |
MA30345B1 (fr) | 2009-04-01 |
KR20080104160A (ko) | 2008-12-01 |
AU2007229554A1 (en) | 2007-10-04 |
CA2647111A1 (fr) | 2007-10-04 |
ECSP088778A (es) | 2008-10-31 |
CN101410137A (zh) | 2009-04-15 |
NO20083895L (no) | 2008-10-24 |
MX2008012295A (es) | 2008-10-09 |
CL2007000797A1 (es) | 2008-01-25 |
BRPI0709229A2 (pt) | 2011-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |