CO6400226A2 - Micrólido anti-inflamatorio - Google Patents

Micrólido anti-inflamatorio

Info

Publication number
CO6400226A2
CO6400226A2 CO11095916A CO11095916A CO6400226A2 CO 6400226 A2 CO6400226 A2 CO 6400226A2 CO 11095916 A CO11095916 A CO 11095916A CO 11095916 A CO11095916 A CO 11095916A CO 6400226 A2 CO6400226 A2 CO 6400226A2
Authority
CO
Colombia
Prior art keywords
inflammatory
microlid
compound
diethylaminoethanyl
homoerythromycin
Prior art date
Application number
CO11095916A
Other languages
English (en)
Inventor
Caroline Jane Day
Julien Bruno Douillet
Darko Filic
Leanda Jane Kindon
Goran Kragol
Zorica Marusic-Istuk
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41698466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6400226(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CO6400226A2 publication Critical patent/CO6400226A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

El compuesto 3'-N-desmetil-4"-O-(2-dietilaminoetanoil)-6-O-metil-9a-aza-9a-homoeritromicina A, que tiene la Fórmula (I):o una sal del mismo, composiciones que comprenden el compuesto, su uso en el tratamiento de enfermedades inflamatorias dominadas por neutrófilos, y métodos para su preparación.
CO11095916A 2009-01-30 2011-07-29 Micrólido anti-inflamatorio CO6400226A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14860909P 2009-01-30 2009-01-30

Publications (1)

Publication Number Publication Date
CO6400226A2 true CO6400226A2 (es) 2012-03-15

Family

ID=41698466

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11095916A CO6400226A2 (es) 2009-01-30 2011-07-29 Micrólido anti-inflamatorio

Country Status (23)

Country Link
US (1) US8227428B2 (es)
EP (1) EP2384333B1 (es)
JP (1) JP5437394B2 (es)
KR (1) KR20110099791A (es)
CN (1) CN102378763A (es)
AR (1) AR075340A1 (es)
AU (1) AU2010209732B2 (es)
BR (1) BRPI1006114A2 (es)
CA (1) CA2748847A1 (es)
CL (1) CL2011001829A1 (es)
CO (1) CO6400226A2 (es)
DO (1) DOP2011000242A (es)
EA (1) EA201101139A1 (es)
ES (1) ES2412059T3 (es)
IL (1) IL213871A0 (es)
MA (1) MA32997B1 (es)
MX (1) MX2011008074A (es)
PE (1) PE20120220A1 (es)
SG (1) SG172782A1 (es)
TW (1) TW201038277A (es)
UY (1) UY32408A (es)
WO (1) WO2010086349A1 (es)
ZA (1) ZA201104653B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006087644A2 (en) 2005-01-13 2006-08-24 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Macrolides with anti-inflammatory activity
SG172782A1 (en) 2009-01-30 2011-08-29 Glaxo Group Ltd Anti-inflammatory macrolide
US20130045939A1 (en) * 2010-03-19 2013-02-21 Catabasis Pharmaceuticals, Inc. Fatty acid macrolide derivatives and their uses
WO2011131749A1 (en) * 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
JP6116206B2 (ja) * 2012-11-26 2017-04-19 クリニプロ株式会社 吸入用パウダーの製造方法
CN110300596A (zh) * 2017-01-13 2019-10-01 东菱药品工业株式会社 嗜中性粒细胞活化调节剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US525051A (en) 1894-08-28 Adjustable chair
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
OA08732A (fr) * 1987-05-06 1989-03-31 Adir Nouveaux dérivés macrolides, leur procédé de préparation et les compositions pharmaceutiques les contenant.
SI9011409A (en) 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
EP0895999A1 (en) 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
HRP980189B1 (en) 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
AU772283B2 (en) * 1999-05-18 2004-04-22 Pfizer Products Inc. Novel crystalline forms of a macrolide antibiotic
HRP20010301A2 (en) 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
JP4790263B2 (ja) 2002-07-08 2011-10-12 グラクソ グループ リミテッド 炎症性の疾患および病態を治療する新規な化合物、組成物および方法
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
GB0310986D0 (en) 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
DE602006004555D1 (de) 2005-01-13 2009-02-12 Glaxosmithkline Zagreb Decladinosyl-macrolide mit entzündungshemmender wirkung
WO2006087644A2 (en) * 2005-01-13 2006-08-24 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Macrolides with anti-inflammatory activity
JP5065910B2 (ja) 2005-01-14 2012-11-07 グラクソ グループ リミテッド ビオチンおよび光親和性基を含む、マクロライド標的同定用のマクロライド化合物
SG172782A1 (en) 2009-01-30 2011-08-29 Glaxo Group Ltd Anti-inflammatory macrolide

Also Published As

Publication number Publication date
CA2748847A1 (en) 2010-08-05
MA32997B1 (fr) 2012-01-02
EP2384333A1 (en) 2011-11-09
MX2011008074A (es) 2011-08-17
BRPI1006114A2 (pt) 2018-02-06
JP5437394B2 (ja) 2014-03-12
ES2412059T3 (es) 2013-07-10
CL2011001829A1 (es) 2011-10-14
EA201101139A1 (ru) 2012-03-30
AU2010209732B2 (en) 2012-12-20
UY32408A (es) 2010-07-30
AR075340A1 (es) 2011-03-23
EP2384333B1 (en) 2013-04-17
SG172782A1 (en) 2011-08-29
IL213871A0 (en) 2011-07-31
DOP2011000242A (es) 2011-09-15
ZA201104653B (en) 2012-02-29
CN102378763A (zh) 2012-03-14
KR20110099791A (ko) 2011-09-08
PE20120220A1 (es) 2012-04-04
US20100197623A1 (en) 2010-08-05
JP2012516304A (ja) 2012-07-19
AU2010209732A1 (en) 2011-07-21
WO2010086349A1 (en) 2010-08-05
TW201038277A (en) 2010-11-01
US8227428B2 (en) 2012-07-24

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