CO6290691A2 - 2-[4-(7-etil-5h-pirrolo[2,3-b]pirazin-6-il)-fenil]-propan-2-ol o una sal farmaceúticamente aceptable o profarmaco del mismo - Google Patents

2-[4-(7-etil-5h-pirrolo[2,3-b]pirazin-6-il)-fenil]-propan-2-ol o una sal farmaceúticamente aceptable o profarmaco del mismo

Info

Publication number
CO6290691A2
CO6290691A2 CO10108103A CO10108103A CO6290691A2 CO 6290691 A2 CO6290691 A2 CO 6290691A2 CO 10108103 A CO10108103 A CO 10108103A CO 10108103 A CO10108103 A CO 10108103A CO 6290691 A2 CO6290691 A2 CO 6290691A2
Authority
CO
Colombia
Prior art keywords
profarmatic
pirazin
pirrolo
etil
penyl
Prior art date
Application number
CO10108103A
Other languages
English (en)
Inventor
Thomas Oligino
Chang Hahn
Ramalinga M Dharanipraga
Timothy Alan Gillespy
Ellen Matzkin
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CO6290691A2 publication Critical patent/CO6290691A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

Se describe un tratamiento para trastornos relacionados con los ojos, tales como la degeneración macular, y preferentemente degeneración macular asociada a la edad, retinopatía diabética, y edema macular diabético, utilizando un compuesto de Fórmula I.
CO10108103A 2008-03-10 2010-09-01 2-[4-(7-etil-5h-pirrolo[2,3-b]pirazin-6-il)-fenil]-propan-2-ol o una sal farmaceúticamente aceptable o profarmaco del mismo CO6290691A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3507308P 2008-03-10 2008-03-10

Publications (1)

Publication Number Publication Date
CO6290691A2 true CO6290691A2 (es) 2011-06-20

Family

ID=40583469

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10108103A CO6290691A2 (es) 2008-03-10 2010-09-01 2-[4-(7-etil-5h-pirrolo[2,3-b]pirazin-6-il)-fenil]-propan-2-ol o una sal farmaceúticamente aceptable o profarmaco del mismo

Country Status (22)

Country Link
EP (1) EP2285378A1 (es)
JP (1) JP2011513488A (es)
KR (1) KR20110009084A (es)
CN (1) CN101965188A (es)
AR (1) AR070975A1 (es)
AU (1) AU2009223501A1 (es)
BR (1) BRPI0909659A2 (es)
CA (1) CA2717991A1 (es)
CL (1) CL2009000551A1 (es)
CO (1) CO6290691A2 (es)
CR (1) CR11644A (es)
DO (1) DOP2010000266A (es)
IL (1) IL207906A0 (es)
MA (1) MA32211B1 (es)
MX (1) MX2010008308A (es)
NI (1) NI201000131A (es)
NZ (1) NZ587906A (es)
RU (1) RU2010141560A (es)
SV (1) SV2010003658A (es)
TW (1) TW200950784A (es)
WO (1) WO2009114373A1 (es)
ZA (1) ZA201005337B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR074776A1 (es) 2008-12-18 2011-02-09 Sanofi Aventis Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ3377A1 (fr) * 1999-12-24 2001-07-05 Aventis Pharma Ltd Azaindoles
JP2003523390A (ja) * 2000-02-25 2003-08-05 メルク エンド カムパニー インコーポレーテッド チロシンキナーゼ阻害薬
US7563787B2 (en) * 2005-09-30 2009-07-21 Miikana Therapeutics, Inc. Substituted pyrazole compounds
CL2007002617A1 (es) * 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.

Also Published As

Publication number Publication date
JP2011513488A (ja) 2011-04-28
CA2717991A1 (en) 2009-09-17
RU2010141560A (ru) 2012-04-20
NI201000131A (es) 2011-09-29
SV2010003658A (es) 2011-01-31
CR11644A (es) 2010-11-22
BRPI0909659A2 (pt) 2015-09-22
WO2009114373A1 (en) 2009-09-17
AR070975A1 (es) 2010-05-19
CN101965188A (zh) 2011-02-02
TW200950784A (en) 2009-12-16
IL207906A0 (en) 2010-12-30
NZ587906A (en) 2011-12-22
AU2009223501A1 (en) 2009-09-17
ZA201005337B (en) 2011-04-28
MX2010008308A (es) 2010-08-11
KR20110009084A (ko) 2011-01-27
EP2285378A1 (en) 2011-02-23
MA32211B1 (fr) 2011-04-01
DOP2010000266A (es) 2010-09-30
CL2009000551A1 (es) 2009-08-21

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