CO6260101A2 - Nuevos genes y proteinas de branchyspira hyodysenteriae y el uso de los mismos - Google Patents

Nuevos genes y proteinas de branchyspira hyodysenteriae y el uso de los mismos

Info

Publication number
CO6260101A2
CO6260101A2 CO10024772A CO10024772A CO6260101A2 CO 6260101 A2 CO6260101 A2 CO 6260101A2 CO 10024772 A CO10024772 A CO 10024772A CO 10024772 A CO10024772 A CO 10024772A CO 6260101 A2 CO6260101 A2 CO 6260101A2
Authority
CO
Colombia
Prior art keywords
plasmid
hyodysenteriae
polynucleotide
brachyspira
useful
Prior art date
Application number
CO10024772A
Other languages
English (en)
Inventor
Matthew Bellgard
David John Hampson
Tom La
Original Assignee
Spirogene Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spirogene Pty Ltd filed Critical Spirogene Pty Ltd
Publication of CO6260101A2 publication Critical patent/CO6260101A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen el nuevo Polinucleótido y los aminoácidos de Brachyspira hyodysenteriae. Estas secuencias son útiles para el diagnóstico de la enfermedad de B. hyodysenteriae en animales y útiles como un tratamiento terapéutico o profiláctico de la enfermedad de B. hyodysenteriae en animales. Estas secuencias pueden también ser útiles para el diagnóstico y para el tratamiento terapéutico y/o profiláctico de enfermedades de los animales causada por Brachyspira en otras especies, incluyendo B. intermedia, B. suantatina, B.alvinipulli B. aalborgi, B.lnnocens, B.murdochii, y B. pilosicoli. 1.- Un polinucleótido que comprende la secuencia seleccionada del grupo que consiste de SEQ ID NO: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 57, 59, 61, 63 y 65. 2.- Un plásmido que comprende el polinucleótido de la reivindicación 1. 3.- El plásmido de la reivindicación 2 en donde dicho plásmido es un vector de expresión. 4.- Una célula que contiene el plásmido de la reivindicación 2. 5.- Una célula que contiene el plásmido de la reivindicación 3. 6.- Una composición inmunogénica que comprende el plásmido de la reivindicación 3. 7.- La composición de la vacuna para el tratamiento o la prevención de Brachyspira hyodysenteriae que comprende el vector de expresión de la reivindicación 3. 8.- La composición de la vacuna para el tratamiento o la prevención de Brachyspira hyodysenteriae que comprende la celda de la reivindicación 4. 9.- Una molécula de ADN que comprende una secuencia que es al menos 70% idéntica a la de los polinucleótidos de la reivindicación 1. 10.- Un plásmido que comprende el polinucleótido de la reivindicación 9.
CO10024772A 2007-08-03 2010-03-03 Nuevos genes y proteinas de branchyspira hyodysenteriae y el uso de los mismos CO6260101A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2007/058049 WO2008017636A2 (en) 2006-08-09 2007-08-03 Genes and proteins of brachyspira hyodysenteriae and uses thereof

Publications (1)

Publication Number Publication Date
CO6260101A2 true CO6260101A2 (es) 2011-03-22

Family

ID=38667160

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10024772A CO6260101A2 (es) 2007-08-03 2010-03-03 Nuevos genes y proteinas de branchyspira hyodysenteriae y el uso de los mismos

Country Status (11)

Country Link
US (2) US8992938B2 (es)
EP (2) EP2185578A2 (es)
JP (1) JP2010535030A (es)
KR (2) KR20100080591A (es)
CN (1) CN101821284B (es)
AU (2) AU2007283667B2 (es)
BR (1) BRPI0721908A2 (es)
CO (1) CO6260101A2 (es)
MX (1) MX2010001381A (es)
UA (1) UA104714C2 (es)
WO (1) WO2008017636A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA104714C2 (ru) * 2007-08-03 2014-03-11 Боерингер Ингельхайм Ветмедика Гмбх Выделенный полинуклеотид brachyspira hyodysenteriae, кодирующий полипептид, и его применение
EP2363407A1 (en) * 2008-02-28 2011-09-07 Murdoch University Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
AU2009227986C1 (en) * 2008-03-27 2014-06-19 Murdoch University Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
AU2013360773B2 (en) 2012-12-21 2018-04-05 Boehringer Ingelheim Vetmedica Gmbh Novel recombinant outer membrane proteins from Brachyspira hyodysenteriae and uses thereof
US10188715B2 (en) 2013-06-28 2019-01-29 Aquilon Cyl Sociedad Limitada Swine dysentery vaccine
EP3107864A4 (en) * 2014-02-17 2018-02-28 William Marsh Rice University Laser induced graphene materials and their use in electronic devices
JP2019500884A (ja) * 2016-01-07 2019-01-17 ウニベルシテイト ヘント ブラキスピラ・ヒオディセンテリアのワクチン株

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
USRE31006E (en) 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4491632A (en) 1979-10-22 1985-01-01 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4342566A (en) 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
EP0043718B1 (en) 1980-07-07 1984-11-28 National Research Development Corporation Improvements in or relating to cell lines
US4341761A (en) 1980-07-25 1982-07-27 E. I. Du Pont De Nemours And Company Antibodies to immunogenic peptides and their use to purify human fibroblast interferon
US4466917A (en) 1981-02-12 1984-08-21 New York University Malaria vaccine
US4493890A (en) 1981-03-23 1985-01-15 Miles Laboratories, Inc. Activated apoglucose oxidase and its use in specific binding assays
US4451570A (en) 1981-03-26 1984-05-29 The Regents Of The University Of California Immunoglobulin-secreting human hybridomas from a cultured human lymphoblastoid cell line
US4399121A (en) 1981-11-04 1983-08-16 Miles Laboratories, Inc. Iodothyronine immunogens and antibodies
US4427783A (en) 1981-12-14 1984-01-24 Hoffmann-La Roche Inc. Immunoassay of thymosin α1
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
CA1319101C (en) 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US6673776B1 (en) 1989-03-21 2004-01-06 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
JPH05502370A (ja) * 1989-09-13 1993-04-28 エムエル　テクノロジー　ヴェンチャーズ　エル．ピー． 分子量３９ｋＤａの赤痢病原体抗原およびそれに対する遺伝子暗号付与
ZA918426B (en) 1990-10-31 1992-12-30 Akzo Nv Chicken anemia virus vaccine and diagnostic
EP0486106A3 (en) 1990-11-16 1992-12-23 Akzo N.V. Marek's disease virus vaccine
US5612487A (en) 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
US6034298A (en) 1991-08-26 2000-03-07 Prodigene, Inc. Vaccines expressed in plants
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US5712118A (en) 1993-09-29 1998-01-27 Research Foundation Of State University Of New York Vaccine for branhamella catarrhalis
US6150170A (en) 1998-05-03 2000-11-21 University Of Maryland At Baltimore Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
US6682729B1 (en) 1995-05-03 2004-01-27 University Of Maryland, Baltimore Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
US5877159A (en) 1995-05-03 1999-03-02 University Of Maryland At Baltimore Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same
US5824538A (en) 1995-09-06 1998-10-20 The United States Of America As Represented By The Secretary Of The Army Shigella vector for delivering DNA to a mammalian cell
AU750106B2 (en) 1997-10-07 2002-07-11 University Of Maryland Biotechnology Institute Method for introducing and expressing RNA in animal cells
EP1159414A4 (en) 1999-09-24 2003-08-27 Cyto Pulse Sciences Inc METHOD FOR PROMOTING ELECTRICALLY ASSISTED ADMINISTRATION OF BIOLOGICAL MATERIALS IN CELLS
AU2001240109A1 (en) 2000-03-07 2001-09-17 U.S. Army Medical Research Institute Of Infectious Diseases Dna vaccines against poxviruses
WO2001068889A2 (en) 2000-03-16 2001-09-20 Malone Robert W Method for gene transfection and vaccination through skin using electropermeabilization
EP1506297A2 (en) * 2002-05-08 2005-02-16 Akzo Nobel N.V. Brachyspira hyodysenteriae vaccine
AU2003250057B2 (en) * 2002-07-17 2008-02-14 Intervet International B.V. Brachyspira hyodysenteriae vaccine
AU2002953431A0 (en) * 2002-12-19 2003-01-09 Murdoch University BmpB Novel Nucleotide and Amino Acid Sequences and Diagnostic and Therapeutic Uses Thereof
US7531176B2 (en) * 2003-12-19 2009-05-12 David J Hampson Brachyspira pilosicoli 72 kDa outer-membrane protein and diagnostic and therapeutic uses thereof
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
EP1882035A2 (en) * 2005-05-12 2008-01-30 Novartis AG Genes and proteins of brachyspira hyodysenteriae and use of same for diagnosis and therapy
WO2007107323A2 (en) * 2006-03-20 2007-09-27 Novartis Ag Novel genes and proteins of brachyspira hyodysenteriae and use of same for diagnosis and therapy
UA104714C2 (ru) * 2007-08-03 2014-03-11 Боерингер Ингельхайм Ветмедика Гмбх Выделенный полинуклеотид brachyspira hyodysenteriae, кодирующий полипептид, и его применение
EP2363407A1 (en) * 2008-02-28 2011-09-07 Murdoch University Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
AU2009227986C1 (en) * 2008-03-27 2014-06-19 Murdoch University Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
AU2009316239B2 (en) * 2008-11-14 2017-10-19 Murdoch University Vaccine strains of Brachyspira hyodysenteriae

Also Published As

Publication number Publication date
US20160052974A1 (en) 2016-02-25
EP3018139A3 (en) 2016-08-10
BRPI0721908A2 (pt) 2014-02-25
EP2185578A2 (en) 2010-05-19
AU2007283667B2 (en) 2014-09-04
KR20140120946A (ko) 2014-10-14
EP3018139A2 (en) 2016-05-11
WO2008017636A3 (en) 2008-04-17
AU2007283667A1 (en) 2008-02-14
US8992938B2 (en) 2015-03-31
WO2008017636A2 (en) 2008-02-14
UA104714C2 (ru) 2014-03-11
KR20100080591A (ko) 2010-07-09
JP2010535030A (ja) 2010-11-18
CN101821284B (zh) 2014-11-19
US20110020383A1 (en) 2011-01-27
CN101821284A (zh) 2010-09-01
MX2010001381A (es) 2010-09-14
AU2014213506A1 (en) 2014-09-04
WO2008017636A8 (en) 2009-10-01

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