CO5261516A1 - Compuestos de n-(i-feniletil)-5-femil-imidazol-2-amina y composicion que los comprende - Google Patents
Compuestos de n-(i-feniletil)-5-femil-imidazol-2-amina y composicion que los comprendeInfo
- Publication number
- CO5261516A1 CO5261516A1 CO00095863A CO00095863A CO5261516A1 CO 5261516 A1 CO5261516 A1 CO 5261516A1 CO 00095863 A CO00095863 A CO 00095863A CO 00095863 A CO00095863 A CO 00095863A CO 5261516 A1 CO5261516 A1 CO 5261516A1
- Authority
- CO
- Colombia
- Prior art keywords
- aryl
- alkyl
- heterocycle
- hydrogen
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Resins (AREA)
Abstract
La presente invención se relaciona con un compuesto que tiene la estructura:<EMI FILE="00095863_1" ID="1" IMF=JPEG >donde:(a) R1 se selecciona del grupo que consiste de alquilo, arilo, y heterociclo;(b) R2 se selecciona del grupo que consiste de hidrógeno, alquilo, arilo, y heterociclo;(c) cada R3 es independientemente se selecciona del que consiste de hidrógeno, halo, alquilo, arilo, heterociclo, nitro, ciano e hidroxi no sustituido o sustituido de alquilo, arilo o heterociclo tio, amino, amida, formilo (acilo), carboxi y carboxamida; dos R3 opcionalmente puede ser alquileno oheteroalquileno, formado de tal modo un anillo fusionado con el fenilo al que está fijado;(d) R4 se selecciona del grupo que consiste de hidrógeno, halo, alquilo, arilo, heterociclo y carboxi y sus ésteres de alquilo y arilo;(e) R7 se selecciona del grupo consistente de hidrógeno, alquilo, arilo y heterociclo;(f) R8 se selecciona del grupo que consiste de hidrógeno, alquilo, alquilacilo, arilacilo, alquilsulfonilo y arilsulfonilo;(g) A es arilo o heterociclo;y un isómero óptico, diastereómero o enantiómero de este; una sal farmacéuticamente aceptable, hidrato o éster, amida o imida biohidrolizables de esta.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17270999P | 1999-12-17 | 1999-12-17 | |
US19281100P | 2000-03-29 | 2000-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5261516A1 true CO5261516A1 (es) | 2003-03-31 |
Family
ID=26868376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00095863A CO5261516A1 (es) | 1999-12-17 | 2000-12-18 | Compuestos de n-(i-feniletil)-5-femil-imidazol-2-amina y composicion que los comprende |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1237876A1 (es) |
JP (1) | JP2003516972A (es) |
KR (1) | KR20020062339A (es) |
CN (1) | CN1411449A (es) |
AU (1) | AU2096901A (es) |
BR (1) | BR0016463A (es) |
CA (1) | CA2394570A1 (es) |
CO (1) | CO5261516A1 (es) |
CZ (1) | CZ20021834A3 (es) |
HU (1) | HUP0204144A3 (es) |
IL (1) | IL149749A0 (es) |
MX (1) | MXPA02005957A (es) |
NO (1) | NO20022844L (es) |
PE (1) | PE20010928A1 (es) |
PL (1) | PL356172A1 (es) |
WO (1) | WO2001044203A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005085241A1 (ja) | 2004-03-05 | 2005-09-15 | Taisho Pharmaceutical Co., Ltd. | チアゾール誘導体 |
EP2513064B1 (en) | 2009-12-17 | 2018-07-04 | Katholieke Universiteit Leuven, K.U. Leuven R&D | Compounds, compositions and methods for controlling biofilms |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459763A (en) * | 1966-01-25 | 1969-08-05 | Geigy Chem Corp | Certain amino imidazole derivatives |
JPS54112864A (en) * | 1978-02-22 | 1979-09-04 | Teijin Ltd | Novel imidazole derivative, its mineral acid salt, and their preparation |
DD135724A1 (de) * | 1978-04-14 | 1979-05-23 | Annemarie Hetzheim | Verfahren zur herstellung von 2-amino-3-phenacyl-benzoxazoliumhalogeniden und 2-amino-1-o-hydroxyphenyl-4-aryl-imidazolen |
US4348404A (en) * | 1980-07-21 | 1982-09-07 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-polyfluoroalkyl-1H-imidazole-2-methanamines |
JPH0753716B2 (ja) * | 1986-07-02 | 1995-06-07 | 吉富製薬株式会社 | イミダゾ−ルカルボキサミド誘導体 |
HUP0201308A3 (en) * | 1999-05-19 | 2003-07-28 | Procter & Gamble | Imidazo-containing heterocyclic compounds, their compositions and uses |
-
2000
- 2000-12-14 KR KR1020027007608A patent/KR20020062339A/ko not_active Application Discontinuation
- 2000-12-14 AU AU20969/01A patent/AU2096901A/en not_active Abandoned
- 2000-12-14 HU HU0204144A patent/HUP0204144A3/hu unknown
- 2000-12-14 PL PL00356172A patent/PL356172A1/xx unknown
- 2000-12-14 BR BR0016463-1A patent/BR0016463A/pt not_active Application Discontinuation
- 2000-12-14 WO PCT/US2000/033820 patent/WO2001044203A1/en not_active Application Discontinuation
- 2000-12-14 CA CA002394570A patent/CA2394570A1/en not_active Abandoned
- 2000-12-14 JP JP2001544693A patent/JP2003516972A/ja not_active Withdrawn
- 2000-12-14 EP EP00984333A patent/EP1237876A1/en not_active Withdrawn
- 2000-12-14 CN CN00817332A patent/CN1411449A/zh active Pending
- 2000-12-14 MX MXPA02005957A patent/MXPA02005957A/es not_active Application Discontinuation
- 2000-12-14 IL IL14974900A patent/IL149749A0/xx unknown
- 2000-12-14 CZ CZ20021834A patent/CZ20021834A3/cs unknown
- 2000-12-15 PE PE2000001352A patent/PE20010928A1/es not_active Application Discontinuation
- 2000-12-18 CO CO00095863A patent/CO5261516A1/es not_active Application Discontinuation
-
2002
- 2002-06-14 NO NO20022844A patent/NO20022844L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2001044203A1 (en) | 2001-06-21 |
PE20010928A1 (es) | 2001-09-12 |
IL149749A0 (en) | 2002-11-10 |
AU2096901A (en) | 2001-06-25 |
CZ20021834A3 (cs) | 2002-10-16 |
NO20022844D0 (no) | 2002-06-14 |
MXPA02005957A (es) | 2002-10-23 |
HUP0204144A2 (en) | 2003-05-28 |
EP1237876A1 (en) | 2002-09-11 |
CA2394570A1 (en) | 2001-06-21 |
PL356172A1 (en) | 2004-06-14 |
CN1411449A (zh) | 2003-04-16 |
NO20022844L (no) | 2002-08-19 |
HUP0204144A3 (en) | 2003-07-28 |
JP2003516972A (ja) | 2003-05-20 |
KR20020062339A (ko) | 2002-07-25 |
BR0016463A (pt) | 2002-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |