CO5080828A1 - Procedimiento para la preparacion de la sal potasica del lintitrip - Google Patents

Procedimiento para la preparacion de la sal potasica del lintitrip

Info

Publication number
CO5080828A1
CO5080828A1 CO99045151A CO99045151A CO5080828A1 CO 5080828 A1 CO5080828 A1 CO 5080828A1 CO 99045151 A CO99045151 A CO 99045151A CO 99045151 A CO99045151 A CO 99045151A CO 5080828 A1 CO5080828 A1 CO 5080828A1
Authority
CO
Colombia
Prior art keywords
preparation
water
lintitrip
procedure
dihydrated
Prior art date
Application number
CO99045151A
Other languages
English (en)
Inventor
Joel Radisson
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of CO5080828A1 publication Critical patent/CO5080828A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

La invención se refiere a un procedimiento para la preparación de la sal potásica dihidratada del ácido 2-[[4-(2-clorofenil)-2-tiazolil]carbamoíl]indol-1-acético, por reacción del ácido 2-[[4-(clorofenil)-2-tiazolil]carbamoíl]indol-1- acético o de sus ésteres alquílicos de 1 a 4 átomos de carbono, con carbonato de potasio en un sistema solvente bifásico constituído por una mezcla de agua con un solvente orgánico poco miscible con el agua, eventual recristalización en agua del solvato intermediario precipitado, y la sal potásico dihidratada así obtenida.
CO99045151A 1998-07-20 1999-07-16 Procedimiento para la preparacion de la sal potasica del lintitrip CO5080828A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9809218A FR2781227B1 (fr) 1998-07-20 1998-07-20 Procede pour la preparation du sel potassique du lintitript

Publications (1)

Publication Number Publication Date
CO5080828A1 true CO5080828A1 (es) 2001-09-25

Family

ID=9528777

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99045151A CO5080828A1 (es) 1998-07-20 1999-07-16 Procedimiento para la preparacion de la sal potasica del lintitrip

Country Status (11)

Country Link
US (1) US6365748B1 (es)
EP (1) EP1098895B1 (es)
JP (1) JP2002521383A (es)
AR (1) AR019421A1 (es)
AT (1) ATE218565T1 (es)
AU (1) AU4628799A (es)
CA (1) CA2338013A1 (es)
CO (1) CO5080828A1 (es)
DE (1) DE69901710D1 (es)
FR (1) FR2781227B1 (es)
WO (1) WO2000005233A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1361220A4 (en) * 2001-01-26 2005-09-07 Shionogi & Co CYCLIC COMPOUNDS WITH THROMBOPOIETIN RECEPTAGONISM
JP2005516011A (ja) * 2001-12-13 2005-06-02 ランバクシー ラボラトリーズ リミテッド 結晶二水化セフニディールカリウム
EP1532980A1 (en) * 2003-11-24 2005-05-25 Novo Nordisk A/S N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
FR2740686B1 (fr) * 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable

Also Published As

Publication number Publication date
ATE218565T1 (de) 2002-06-15
JP2002521383A (ja) 2002-07-16
EP1098895B1 (fr) 2002-06-05
US6365748B1 (en) 2002-04-02
EP1098895A1 (fr) 2001-05-16
FR2781227B1 (fr) 2002-02-22
FR2781227A1 (fr) 2000-01-21
CA2338013A1 (en) 2000-02-03
AU4628799A (en) 2000-02-14
DE69901710D1 (de) 2002-07-11
WO2000005233A1 (fr) 2000-02-03
AR019421A1 (es) 2002-02-20

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