CO2023014836A2 - Hidrogeles de colágenos útiles como vehículos celulares - Google Patents
Hidrogeles de colágenos útiles como vehículos celularesInfo
- Publication number
- CO2023014836A2 CO2023014836A2 CONC2023/0014836A CO2023014836A CO2023014836A2 CO 2023014836 A2 CO2023014836 A2 CO 2023014836A2 CO 2023014836 A CO2023014836 A CO 2023014836A CO 2023014836 A2 CO2023014836 A2 CO 2023014836A2
- Authority
- CO
- Colombia
- Prior art keywords
- fibers
- range
- mass
- collagen
- acid mass
- Prior art date
Links
- 239000000017 hydrogel Substances 0.000 title abstract 3
- 102000008186 Collagen Human genes 0.000 title abstract 2
- 108010035532 Collagen Proteins 0.000 title abstract 2
- 230000001413 cellular effect Effects 0.000 title abstract 2
- 229920001436 collagen Polymers 0.000 title abstract 2
- 239000000835 fiber Substances 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Artificial Filaments (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se divulga un hidrogel de colágeno que comprende una estructura fibrilar 3D con microporos, obtenible mediante un proceso que comprende: proporcionar una masa ácida de fibras de colágeno de tipo I nativo dispersadas en agua en una concentración comprendida entre 1-15 % en peso; b) neutralizar la masa ácida para ajustar el pH al pH fisiológico; y c) aplicar radiación beta en un intervalo de hasta 50 KGy; en donde la masa ácida tiene un pH comprendido entre 0,5-5; y fibras, en donde la masa ácida comprende fibras, en donde al menos un 90 % de la masa total de las fibras tiene una longitud comprendida en un intervalo de 1 µm a 2500 µm y un diámetro de las fibras comprendido en un intervalo de 0,1 a 150 µm medido a un pH entre 1 y 2. También se divulga un proceso para su preparación, así como su uso como soporte para tejido celular o como armazón de carne cultivada, así como el hidrogel para usar en aplicaciones biomédicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21382331 | 2021-04-19 | ||
| PCT/EP2022/060241 WO2022223518A1 (en) | 2021-04-19 | 2022-04-19 | Collagen hydrogels useful as cell carriers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2023014836A2 true CO2023014836A2 (es) | 2024-02-05 |
Family
ID=75625524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2023/0014836A CO2023014836A2 (es) | 2021-04-19 | 2023-10-31 | Hidrogeles de colágenos útiles como vehículos celulares |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP4326354A1 (es) |
| JP (1) | JP2024517509A (es) |
| KR (1) | KR20240005757A (es) |
| CN (1) | CN117769445A (es) |
| AU (1) | AU2022262194A1 (es) |
| BR (1) | BR112023021555A2 (es) |
| CA (1) | CA3214906A1 (es) |
| CO (1) | CO2023014836A2 (es) |
| IL (1) | IL307765A (es) |
| WO (1) | WO2022223518A1 (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786400B1 (fr) | 1998-11-30 | 2002-05-10 | Imedex Biomateriaux | Procede de preparation d'un materiau collagenique a vitesse de biodegradation in vivo controlee et materiaux obtenus |
| MX2010009694A (es) * | 2010-09-03 | 2011-03-31 | Luis Miguel Solis Morales | Proceso de obtencion de un extracto rico en colageno a partir de pieles de animales y dicho extracto. |
-
2022
- 2022-04-19 CA CA3214906A patent/CA3214906A1/en active Pending
- 2022-04-19 CN CN202280029589.0A patent/CN117769445A/zh active Pending
- 2022-04-19 KR KR1020237039647A patent/KR20240005757A/ko unknown
- 2022-04-19 EP EP22722844.2A patent/EP4326354A1/en active Pending
- 2022-04-19 JP JP2024507063A patent/JP2024517509A/ja active Pending
- 2022-04-19 IL IL307765A patent/IL307765A/en unknown
- 2022-04-19 WO PCT/EP2022/060241 patent/WO2022223518A1/en active Application Filing
- 2022-04-19 BR BR112023021555A patent/BR112023021555A2/pt unknown
- 2022-04-19 AU AU2022262194A patent/AU2022262194A1/en active Pending
-
2023
- 2023-10-31 CO CONC2023/0014836A patent/CO2023014836A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112023021555A2 (pt) | 2024-01-30 |
| IL307765A (en) | 2023-12-01 |
| CN117769445A (zh) | 2024-03-26 |
| EP4326354A1 (en) | 2024-02-28 |
| KR20240005757A (ko) | 2024-01-12 |
| JP2024517509A (ja) | 2024-04-22 |
| CA3214906A1 (en) | 2022-10-27 |
| WO2022223518A1 (en) | 2022-10-27 |
| AU2022262194A1 (en) | 2023-10-26 |
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