CO2022008102A2 - Proceso e intermediarios para la producción de fórmula (i) - Google Patents

Proceso e intermediarios para la producción de fórmula (i)

Info

Publication number
CO2022008102A2
CO2022008102A2 CONC2022/0008102A CO2022008102A CO2022008102A2 CO 2022008102 A2 CO2022008102 A2 CO 2022008102A2 CO 2022008102 A CO2022008102 A CO 2022008102A CO 2022008102 A2 CO2022008102 A2 CO 2022008102A2
Authority
CO
Colombia
Prior art keywords
intermediates
formula
production
compound
making
Prior art date
Application number
CONC2022/0008102A
Other languages
English (en)
Inventor
Jerome Dubiez
Andrew Turner
Richard Chubb
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CO2022008102A2 publication Critical patent/CO2022008102A2/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un proceso e intermediarios para hacer el compuesto de Fórmula (I).
CONC2022/0008102A 2019-12-05 2022-06-07 Proceso e intermediarios para la producción de fórmula (i) CO2022008102A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962943851P 2019-12-05 2019-12-05
PCT/EP2020/084580 WO2021110893A1 (en) 2019-12-05 2020-12-04 Process and intermediates for the production of formula (i)

Publications (1)

Publication Number Publication Date
CO2022008102A2 true CO2022008102A2 (es) 2022-07-08

Family

ID=73748050

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2022/0008102A CO2022008102A2 (es) 2019-12-05 2022-06-07 Proceso e intermediarios para la producción de fórmula (i)

Country Status (13)

Country Link
US (1) US20230046093A1 (es)
EP (1) EP4069687B1 (es)
JP (1) JP2023505771A (es)
KR (1) KR20220112764A (es)
CN (1) CN114746410A (es)
AR (1) AR120685A1 (es)
AU (1) AU2020397222B2 (es)
CA (1) CA3157504A1 (es)
CO (1) CO2022008102A2 (es)
IL (1) IL293382A (es)
MX (1) MX2022006856A (es)
TW (1) TW202134242A (es)
WO (1) WO2021110893A1 (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR122020014933B8 (pt) * 2014-04-09 2022-12-13 Genentech Inc Compostos, composições farmacêuticas, benzenossulfonatos, forma a de ácido p-toluenossulfônico, forma b de ácido p-toluenssulfônico, forma i do ácido naftalenodissulfônico e forma ii do ácido naftalendissulfônico
UY36629A (es) * 2015-04-17 2016-11-30 Abbvie Inc Indazolonas como moduladores de la señalización de tnf
BR112018008397B1 (pt) * 2015-11-09 2023-12-12 Astrazeneca Ab Composto, sal farmacêuticamente aceitável e formas cristalinas
ES2789756T3 (es) * 2015-12-23 2020-10-26 Merck Sharp & Dohme Moduladores alostéricos de 6,7-dihidro-5H-pirrolo[3,4-b]piridin-5-ona del receptor de acetilcolina muscarínico M4

Also Published As

Publication number Publication date
EP4069687B1 (en) 2024-01-31
TW202134242A (zh) 2021-09-16
AU2020397222B2 (en) 2023-07-06
MX2022006856A (es) 2022-07-11
AU2020397222A1 (en) 2022-04-28
JP2023505771A (ja) 2023-02-13
CA3157504A1 (en) 2021-06-10
WO2021110893A1 (en) 2021-06-10
KR20220112764A (ko) 2022-08-11
EP4069687A1 (en) 2022-10-12
AR120685A1 (es) 2022-03-09
IL293382A (en) 2022-07-01
CN114746410A (zh) 2022-07-12
US20230046093A1 (en) 2023-02-16

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