CO2017013041A2 - Método para tratar tumores neuroendocrinos donde se sobreexpresan receptores de somatostatatina - Google Patents
Método para tratar tumores neuroendocrinos donde se sobreexpresan receptores de somatostatatinaInfo
- Publication number
- CO2017013041A2 CO2017013041A2 CONC2017/0013041A CO2017013041A CO2017013041A2 CO 2017013041 A2 CO2017013041 A2 CO 2017013041A2 CO 2017013041 A CO2017013041 A CO 2017013041A CO 2017013041 A2 CO2017013041 A2 CO 2017013041A2
- Authority
- CO
- Colombia
- Prior art keywords
- overexpressed
- receptors
- somatostatatin
- neuroendocrine tumors
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Métodos para tratar cánceres donde se sobreexpresan receptores de somatostatina. Terapia combinada donde se administra una combinación de una terapia con péptidos receptores marcados con radioisótopos (PRRT) y una terapia inmunooncológica (terapia I-O) para tratar tumores neuroendocrinos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562176901P | 2015-06-25 | 2015-06-25 | |
PCT/IB2016/001089 WO2016207732A1 (en) | 2015-06-25 | 2016-06-24 | Method of treatment of neuroendocrine tumors that over-express somatostatatin receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2017013041A2 true CO2017013041A2 (es) | 2018-03-28 |
Family
ID=56940095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2017/0013041A CO2017013041A2 (es) | 2015-06-25 | 2017-12-19 | Método para tratar tumores neuroendocrinos donde se sobreexpresan receptores de somatostatatina |
Country Status (12)
Country | Link |
---|---|
US (2) | US20180185524A1 (es) |
EP (2) | EP3313888A1 (es) |
JP (3) | JP2018518526A (es) |
KR (1) | KR20180041623A (es) |
CN (1) | CN108137690A (es) |
CA (1) | CA2989266A1 (es) |
CO (1) | CO2017013041A2 (es) |
HK (1) | HK1254404A1 (es) |
IL (1) | IL256543B (es) |
MX (1) | MX2017016863A (es) |
SG (1) | SG10201913964QA (es) |
WO (1) | WO2016207732A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11633506B2 (en) | 2016-07-18 | 2023-04-25 | Wisconsin Alumni Research Foundation | Using targeted radiotherapy (TRT) to drive anti-tumor immune response to immunotherapies |
KR20200088374A (ko) * | 2017-11-10 | 2020-07-22 | 위스콘신 얼럼나이 리서어치 화운데이션 | 면역요법에 대한 항-종양 면역 반응을 유도하기 위해 표적화된 방사선요법(trt)을 이용하는 방법 |
CN112955188A (zh) * | 2018-07-25 | 2021-06-11 | 先进加速器应用公司 | 治疗神经内分泌肿瘤的方法 |
US10596278B2 (en) | 2018-07-25 | 2020-03-24 | Advanced Accelerator Applications (Italy) S.R.L. | Stable, concentrated radionuclide complex solutions |
US10596276B2 (en) | 2018-07-25 | 2020-03-24 | Advanced Accelerator Applications (Italy) S.R.L. | Stable, concentrated radionuclide complex solutions |
WO2020021465A1 (en) | 2018-07-25 | 2020-01-30 | Advanced Accelerator Applications (Italy) S.R.L. | Method of treatment of neuroendocrine tumors |
EP3693974A1 (en) * | 2019-02-07 | 2020-08-12 | Koninklijke Philips N.V. | Identifying responsiveness to radio-immuno combination therapy |
CN113616818B (zh) * | 2020-05-06 | 2023-04-25 | 北京大学 | 一种用于肿瘤的靶向放射与免疫联合治疗的药物组合物 |
TW202214674A (zh) * | 2020-06-29 | 2022-04-16 | 大陸商北京拓界生物醫藥科技有限公司 | 一種放射性核種標記化合物及其應用 |
CN111840585B (zh) * | 2020-07-20 | 2022-05-03 | 厦门大学 | 一种用于肿瘤免疫治疗的药物组合 |
CA3190855A1 (en) | 2020-08-27 | 2022-03-03 | Joe Mccann | Radiopharmaceutical and methods |
US11541134B1 (en) | 2021-08-02 | 2023-01-03 | Rayzebio, Inc. | Stabilized compositions of radionuclides and uses thereof |
WO2023084445A1 (en) | 2021-11-12 | 2023-05-19 | Novartis Ag | Combination therapy for treating lung cancer |
WO2023208341A1 (en) | 2022-04-27 | 2023-11-02 | ITM Isotope Technologies Munich SE | Combination treatment of small-cell lung cancer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830431A (en) | 1995-06-07 | 1998-11-03 | Mallinckrodt Medical, Inc. | Radiolabeled peptide compositions for site-specific targeting |
EP2456790A1 (en) * | 2009-07-20 | 2012-05-30 | Bristol-Myers Squibb Company | Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases |
US9150656B2 (en) * | 2010-03-04 | 2015-10-06 | Macrogenics, Inc. | Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof |
CN104491890A (zh) * | 2014-11-21 | 2015-04-08 | 北京肿瘤医院 | 放射性核素标记的新型生长抑素类似物分子探针及其应用 |
-
2016
- 2016-06-24 WO PCT/IB2016/001089 patent/WO2016207732A1/en active Application Filing
- 2016-06-24 JP JP2017567306A patent/JP2018518526A/ja active Pending
- 2016-06-24 CA CA2989266A patent/CA2989266A1/en active Pending
- 2016-06-24 CN CN201680048940.5A patent/CN108137690A/zh active Pending
- 2016-06-24 SG SG10201913964QA patent/SG10201913964QA/en unknown
- 2016-06-24 MX MX2017016863A patent/MX2017016863A/es unknown
- 2016-06-24 EP EP16766600.7A patent/EP3313888A1/en not_active Withdrawn
- 2016-06-24 US US15/739,234 patent/US20180185524A1/en not_active Abandoned
- 2016-06-24 EP EP23203339.9A patent/EP4286008A3/en active Pending
- 2016-06-24 KR KR1020177037167A patent/KR20180041623A/ko not_active Application Discontinuation
-
2017
- 2017-12-19 CO CONC2017/0013041A patent/CO2017013041A2/es unknown
- 2017-12-25 IL IL256543A patent/IL256543B/en unknown
-
2018
- 2018-10-22 HK HK18113483.7A patent/HK1254404A1/zh unknown
-
2019
- 2019-12-16 JP JP2019226638A patent/JP2020040992A/ja active Pending
-
2022
- 2022-01-20 US US17/579,909 patent/US20220143227A1/en active Pending
- 2022-10-31 JP JP2022174286A patent/JP2023002792A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20180185524A1 (en) | 2018-07-05 |
EP4286008A3 (en) | 2024-02-28 |
CA2989266A1 (en) | 2016-12-29 |
EP3313888A1 (en) | 2018-05-02 |
HK1254404A1 (zh) | 2019-07-19 |
IL256543B (en) | 2022-01-01 |
JP2020040992A (ja) | 2020-03-19 |
WO2016207732A1 (en) | 2016-12-29 |
EP4286008A2 (en) | 2023-12-06 |
KR20180041623A (ko) | 2018-04-24 |
JP2023002792A (ja) | 2023-01-10 |
IL256543A (en) | 2018-02-28 |
JP2018518526A (ja) | 2018-07-12 |
US20220143227A1 (en) | 2022-05-12 |
MX2017016863A (es) | 2018-09-06 |
SG10201913964QA (en) | 2020-03-30 |
CN108137690A (zh) | 2018-06-08 |
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