CN2314424Y - Apparatus for simulating curves of in vivo media changes - Google Patents
Apparatus for simulating curves of in vivo media changes Download PDFInfo
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- CN2314424Y CN2314424Y CN 97242843 CN97242843U CN2314424Y CN 2314424 Y CN2314424 Y CN 2314424Y CN 97242843 CN97242843 CN 97242843 CN 97242843 U CN97242843 U CN 97242843U CN 2314424 Y CN2314424 Y CN 2314424Y
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- power pump
- bottle
- surge flask
- curve
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Abstract
The utility model relates to a device for simulating the medium change curve in a body, belonging to a field of image medicine and clinical test. A high pressure syringe is used as a motive power pump, and the pumped liquid is mixed with the contrast medium which is injected by a guide tube by-pass path micro syringe and enters a perfusion area of a tissue organ through a big and a small buffering bottles after even distribution. Through the test, the utility model has the characteristic of actual perfusion in a human body and can simulate the medium curve change in the body. The device has the advantages of low cost and simple manufacture and is suitable for the field of hemodynamics and related research.
Description
The utility model belongs to medical imaging, clinical examination field.
Often need some medium of intravenous injection in medical diagnosis, the therapeutic process, as: dyestuff, contrast preparation, isotope or other medicines enter in the body.There are some researches prove that these media present a kind of specific γ-curvilinear motion in vivo.Understand the change shape of these curves, help to grasp physiology, pathologic process and the relevant functional response of some internal organs.Recently medical image technology CT, MRI, etc. adopt the way of quiet notes contrast preparation or tracer agent, relevant pathology is diagnosed in the variation of non-invasive contrast agent detection curve, and then computation organization's perfusion flow.The approach of verifying this result reliability often is by zooperal " isotope labeling microballoon method ", but its technical requirement complexity and accuracy are not high.And external model has the characteristics of accuracy height, good reproducibility, so can be used for checking the accuracy of these image technologies.Utilization heart-lung machines such as China Du Luo mountain carry out the model determination of coronarography, need special device, and do not conform to the image technology development trend in noninvasive testing; External Jaschk.w etc. use " magnetic stirrer " to realize the mechanical mixture of contrast preparation and solution, the instrument complexity, and its stability is also relatively poor, the γ of the in-vivo medium of also having no talent-curve characteristics.
The purpose of this utility model provides a kind of in-vivo medium change curve device, change curve by the agent of analogue body interimage, for the relation of quantitative examination contrast agent dosage-curved line relation and tissue district groundwater increment is set up scientific basic and mathematic(al) mode, simultaneously, the standard of this device can be used for detecting, proofreading and correct the accuracy of relevant radiographic measurement technology.
The utility model adopts high pressure injector as power pump 1, solution that is pumped by power pump and the micro syringe of input pipe 3 bypasses 2 inject contrast preparation and enter big surge flask 4 through conduit simultaneously, after carrying out the dynamic mixing of liquid, enter minibuffer bottle 6 through connecting duct 5, further after the homogenising, enter the perfusion area 8,9 of histoorgan through output duct 7.At this moment, in this conduit after the variation of liquid interimage agent concentration and the intravenous injection agent of human body interimage change basically identical, be rendered as the process of γ-curve, reliable in the each point measurement result stable equilibrium of output duct.
The utility model power pump employing capacity is the high pressure injector that is not less than 180ml, pumping liquid velocity is 5ml-15ml/ second, to keep constant liquid output amount to enter big surge flask, it is other that micro syringe is located at conduit 3, its injection volume generally is not more than 6.0ml, inject the speed of contrast preparation and be advisable second with 1.0-1.5ml/, the liquid that is mixed with contrast preparation is the conduit of 3-4mm by internal diameter, successively enters large and small glass surge flask.In the utility model surge flask the end be smooth seamless in bottle dimpling, its volume is respectively big surge flask 100-150ml, minibuffer bottle 20-50ml, and both total volumies are 120-200ml, import at a high speed in the big surge flask when the solution that is mixed with contrast preparation, bottleneck backflows through the surge flask bottom surface.This process makes contrast preparation reach dynamic mixing in solution, further mixes in the minibuffer bottle again, reaches following effect: 1. produce to the intravenous injection contrast preparation after in arterial system similar perfusion curve; 2. solution concentration equates in arbitrary xsect, and it is also similar substantially that institute surveys the curve of generation, thereby reduce the error that its zones of different is taken a sample; 3. the control by surge flask and injection speed can produce permanent steady specific curve.
Through advance copy utility model device, have the feature of actual perfusion in the human body, the γ-curvilinear motion that can simulate the in-vivo medium complexity, this installation cost is low, and is simple for production, applicable to Hemodynamics test and Related Research Domain.
Embodiment 1: adopt the interior diametered duct of 3mm to connect big surge flask 110ml, minibuffer bottle 30ml, pump solution 10ml/ second with the 180ml high pressure injector, inject contrast preparation Omnipaque5ml second with micro syringe 1.5ml/, carry out carrying out behind the perfused tissue perfusion area analysis of certain volume, detect the curve basically identical in arteries perfused tissue district in its tracing pattern and the human body through electron beam ct.
The drawing explanation:
Fig. 1 is an in-vivo medium change curve device simulation drawing
1 power pump wherein
2 micro syringes
3 input pipes
4 big surge flasks
5 connecting ducts
6 minibuffer bottles
7 output ducts
8,9 histoorgan perfusion areas
Fig. 2 is that the blood vessel in the human body body compares with cardiac muscular tissue's curve and simulation curve
Blood vessel and the cardiac muscular tissue's curve in 1 human body wherein
2 simulation curves
Claims (4)
1. media variations curve device in the analogue body that has a power pump, it is characterized in that the liquid that power pump 1 pumps enters big surge flask 4 by the input pipe 3 that has bypass micro syringe 2, after carrying out the dynamic mixing of liquid, in entering minibuffer bottle 6, connecting duct 5 after the further homogenising, enters the perfusion area 8,9 of histoorgan through output duct 7.
2. by the described in-vivo medium change curve device that has power pump of claim 1, it is characterized in that described power pump can be a high pressure injector, its volume is not less than 180ml, and injection speed is 3-15ml/ second.
3. by media variations curve device in the described analogue body that has a power pump of claim 1, the end that it is characterized in that described surge flask, is smooth seamless, and dimpling in bottle, its capacity are big surge flask 100-150ml, minibuffer bottle 20-50ml, total volume is 120-200ml.
4. by media variations curve device in the described analogue body that has a power pump of claim 1, it is characterized in that described micro syringe injection speed is 0.5-2.0ml/ second, injection volume is not more than 6.0ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97242843 CN2314424Y (en) | 1997-12-08 | 1997-12-08 | Apparatus for simulating curves of in vivo media changes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97242843 CN2314424Y (en) | 1997-12-08 | 1997-12-08 | Apparatus for simulating curves of in vivo media changes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2314424Y true CN2314424Y (en) | 1999-04-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97242843 Expired - Fee Related CN2314424Y (en) | 1997-12-08 | 1997-12-08 | Apparatus for simulating curves of in vivo media changes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2314424Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102334987A (en) * | 2010-07-23 | 2012-02-01 | 复旦大学 | Monitoring system and test method for measuring dynamic change of pressure of tissue space |
| CN105637572A (en) * | 2014-02-12 | 2016-06-01 | 奥林巴斯株式会社 | Pseudo-human body device |
| CN111312048A (en) * | 2014-11-10 | 2020-06-19 | 国立大学法人大阪大学 | Radiography method for catheter simulator |
| CN112641427A (en) * | 2020-09-08 | 2021-04-13 | 暨南大学附属第一医院（广州华侨医院） | System for evaluating in-vivo metabolism of iodine contrast agent and preventing risks |
-
1997
- 1997-12-08 CN CN 97242843 patent/CN2314424Y/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102334987A (en) * | 2010-07-23 | 2012-02-01 | 复旦大学 | Monitoring system and test method for measuring dynamic change of pressure of tissue space |
| CN105637572A (en) * | 2014-02-12 | 2016-06-01 | 奥林巴斯株式会社 | Pseudo-human body device |
| CN111312048A (en) * | 2014-11-10 | 2020-06-19 | 国立大学法人大阪大学 | Radiography method for catheter simulator |
| US11151903B2 (en) | 2014-11-10 | 2021-10-19 | Osaka University | Imaging method for catheter simulator |
| CN112641427A (en) * | 2020-09-08 | 2021-04-13 | 暨南大学附属第一医院（广州华侨医院） | System for evaluating in-vivo metabolism of iodine contrast agent and preventing risks |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |