CN2263790Y - Middle low pressure liquid phase chromatograph apparatus - Google Patents
Middle low pressure liquid phase chromatograph apparatus Download PDFInfo
- Publication number
- CN2263790Y CN2263790Y CN 96202823 CN96202823U CN2263790Y CN 2263790 Y CN2263790 Y CN 2263790Y CN 96202823 CN96202823 CN 96202823 CN 96202823 U CN96202823 U CN 96202823U CN 2263790 Y CN2263790 Y CN 2263790Y
- Authority
- CN
- China
- Prior art keywords
- lower cover
- chromatographic column
- glass cylinder
- groove
- moving phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The utility model provides a middle low pressure liquid phase chromatograph apparatus. A nitrogen bottle supplies pressure to a pressure tank, liquid phase inside the tank is pressed in a chromatographic column, and finished goods purified through the chromatographic column flows into a collecting container. The utility model is characterized in that the pressure tank is composed of a glass column body and an upper and a lower covers, the upper cover is provided with a liquid feed inlet and a gas inlet, and the lower cover is provided with a mobile phase outlet 6; the chromatographic column is composed of a glass column body whose both ends are expanded, an upper cover and an upper cover connecting body, a lower cover and a lower cover connecting body, the upper cover is provided with a mobile phase inlet, the lower cover is provided with a mobile phase outlet, and the integral apparatus compose a sealed pressure resisting body. The middle low pressure liquid phase chromatograph apparatus has simple structure, convenient use and good pressure resistance (0-10 kg/cm 2) and sealing performance, and the utility model can be widely used for separating organic and inorganic compounds.
Description
The utility model relates to a kind of compartment analysis device of organic-inorganic compound, specifically a kind of mesolow liquid-chromatography apparatus.
At present, be used for the compartment analysis of natural products, protein and all kinds of organic-inorganic compounds, use the mesolow chromatogram, but domesticly still do not have this type of mesolow liquid-chromatography apparatus, more can't enter the practical scale of preparation of industrialization and production.
The purpose of this utility model is to provide a kind of mesolow liquid-chromatography apparatus, and it has rational in infrastructure, and is easy to use, and sealing and good pressure-resistant performance can be used for characteristics such as preparation of industrialization amount production.
The purpose of this utility model such as following means realize.
A kind of mesolow liquid-chromatography apparatus, comprise that the nitrogen cylinder voltage supply is to head tank, and liquid phase is imported chromatographic column form with the collection container that receives finished product, it is characterized in that head tank is by glass cylinder and last, lower cover constitutes, on be covered with filling opening and air intake opening, under be covered with moving phase outlet, the glass cylinder of head tank adopts transparent hard glass, on, lower cover is the polyoxymethylene material, last, under cover and have and the concentric isometrical garden of glass cylinder groove, in the groove with the sealing of fluororubber O shape O-ring seal, and last, on the symmetric points of lower cover, be positioned at outside the periphery of glass cylinder, will go up with metallic stud, lower cover and glass cylinder sealing connection are a withstand voltage integral body.Chromatographic column is by the glass cylinder of two ends enlarging, loam cake and loam cake connector, lower cover and lower cover connector constitute, on be covered with the moving phase import, be covered with the moving phase outlet down.The upper and lower cover connector of chromatographic column is formed by the bumper ring of the fluororubber of back taper and the polyoxymethylene lasso wringing fit of back taper.Have the concentric isometrical garden of upper and lower end enlarging groove on the upper and lower cover of chromatographic column with the glass cylinder, seal with fluororubber O shape O-ring seal in the groove, upper and lower cover is connected sealing with the upper and lower cover connector by bolt, the following of chromatographic column covers, be positioned at the O-ring seals inboard, moving phase outlet radially opened groove, the both sides of groove have the mill line.
The mesolow liquid-chromatography apparatus that the utility model provides, comprise nitrogen cylinder, head tank, chromatographic column and collection container are formed, it is characterized in that head tank is made of glass cylinder and upper and lower cover, on be covered with filling opening and air intake opening, be covered with down the moving phase outlet, chromatographic column is by the glass cylinder of two ends enlarging, loam cake and loam cake connector, lower cover and lower cover connector constitute, on be covered with the moving phase import, be covered with the moving phase outlet down.This device, simple in structure, easy to use, the good (0～10kg/cm of pressure-resistant seal performance
2, decide according to chromatogram inserts and the selection of glass cylinder), can be widely used in the practical scale of preparation of industrialization and production, be applicable to pharmacy, food, cosmetics, the purifying products in fields such as health care and biological chemistry.
The utlity model has following accompanying drawing.
Fig. 1 is a structural representation of the present utility model.
Below in conjunction with accompanying drawing the utility model is described in detail.
Embodiment.
A kind of mesolow liquid-chromatography apparatus, its structure as shown in Figure 1.This installs by nitrogen cylinder 1, head tank 2, and chromatographic column 3 and collection container 4 are formed.Head tank 2 constitutes one by the glass cylinder 9 of transparent hard glass and the upper and lower cover 5,6 of polyoxymethylene material, processes respectively and glass cylinder 9 concentric isometrical garden grooves on the upper and lower cover 5,6, with fluororubber O shape O-ring seal 18,18 ｀ sealing; At 6 points of the symmetry of upper and lower cover 5,6, be positioned at the outer ring of glass cylinder 9, be a withstand voltage integral body with metallic stud 19 with upper and lower cover 5,6 and glass cylinder 9, be wrapped with adhesive tape on the glass cylinder 9 during use.Loam cake 5 is provided with filling opening 7, be made up of outstanding screw rod, nut, and by the silicon rubber seal with O ring, another is to outstanding screw rod, and nut has constituted air intake opening 8, and uses the silicon rubber seal with O ring.Inserting the cannulated threaded pipe on the lower end 6 is moving phase outlet 10, and uses the silicon rubber seal with O ring.Chromatographic column 3 is by the glass cylinder 11 of two ends enlarging, the loam cake 12 and the loam cake connector 13 of polyoxymethylene material, the lower cover 14 of polyoxymethylene material constitutes at connector 15 with lower cover, loam cake 12 is provided with moving phase import 16, be made up of outstanding screw rod, nut, silicon rubber seal with O ring, lower cover 14 are provided with moving phase outlet 17, form by the cannulated threaded pipe that inserts lower cover 14, and use the silicon rubber seal with O ring.Wherein the upper and lower cover connector 13,15, constitute by bumper ring 20,20 ｀ of the fluororubber of back taper and polyoxymethylene lasso 21, the 21 ｀ wringing fits of back taper, and bumper ring 20,20 ｀ directly contact with glass cylinder 11 during sealing.Have the concentric isometrical garden of upper and lower end enlarging groove on the upper and lower cover 12,14 with glass cylinder 11, in the groove with fluororubber O shape O-ring seal 22,22 ' do sealing, upper and lower cover 12,14 and upper and lower cover connector 13,15 are connected sealing by bolt, the outlet of moving phase on the lower cover 14 of the chromatographic column 3 of O-ring seals 22 ｀ inboards radially opened groove, the both sides of groove have the mill line.Pressure nitrogen gas in the nitrogen cylinder 1 is derived from reduction valve 23, air intake opening 8 through four-way valve 24 and loam cake 5 enters in the head tank 2, the moving phase that enters through filling opening 7, under the effect of pressure, through moving phase outlet 10, flowing out conduit is the four fluorine tube of the soft silicon rubber of overcoat, enters chromatographic column 3 from the moving phase import 16 of chromatographic column 3, and its product advances moving phase outlet 17 again and enters beaker 4.In addition, can connect a head tank 2 again, when the moving phase in the head tank is about to use up,, enable the moving phase in another head tank 2 by rotary valve at the other end of four-way valve 24, but also gradient elution usefulness, another logical atmosphere in the four-way valve.
Application example:
In the purifies and separates process of bavin China fir alcohol, the chromatographic column of internal diameter 7.5cm is adorned the silica filler of 15 μ, head tank volume 3500ml (internal diameter 150mm), and acetone is done elute soln, single injected sampling 70g, product 7.8g, wash-out pressure is no more than 2.5kg/cm
2, whole elution process quantity of solvent is two head tank volumes, elution time 100 minutes.
Claims (5)
1. mesolow liquid-chromatography apparatus, by nitrogen cylinder (1) voltage supply, give head tank (2), and the liquid phase in the jar is pressed into chromatographic column (3), after separating, in collection container (4), collects chromatographic column (3), it is characterized in that: (1) head tank (2) is by glass cylinder (9) and last, lower cover (5), (6) constitute, loam cake (5) is provided with filling opening (7) and air intake opening (8), lower cover (6) is provided with moving phase outlet (10), (2) chromatographic column (3) is by the glass cylinder (11) of two ends enlarging, loam cake (12) and loam cake connector (13), lower cover (14) is formed with lower cover connector (15), loam cake (12) is provided with moving phase import (16), and lower cover (14) is provided with moving phase outlet (17).
2. mesolow liquid-chromatography apparatus as claimed in claim 1, the glass cylinder (9) that it is characterized in that head tank (2) adopts transparent hard glass, upper and lower cover (5), (6) are polyoxymethylene, on upper and lower cover (5), (6), have the concentric isometrical garden of glass cylinder (9) groove, do encapsulant with fluororubber O shape circle (18), (18 ｀) in the groove, the symmetric points of upper and lower cover (5), (6), outer ring in glass cylinder (9) is sealed into a withstand voltage integral body with metallic stud (19) with upper and lower cover (5), (6) and glass cylinder (9).
3. mesolow liquid-chromatography apparatus as claimed in claim 1, the upper and lower cover connector (13), (15) that it is characterized in that chromatographic column (3) are made up of with polyoxymethylene lasso (21), (21 ｀) wringing fit of back taper bumper ring (20), (20 ｀) of the fluororubber of back taper.
4. mesolow liquid-chromatography apparatus as claimed in claim 1, it is characterized in that having on the upper and lower cover (12), (14) of chromatographic column (3) the concentric isometrical garden of upper and lower port groove with glass cylinder (11), do encapsulant with fluororubber O shape circle (22), (22 ｀) in the groove, upper and lower cover (12), (14) are connected sealing with upper and lower cover connector (13), (15) by bolt.
5. mesolow liquid-chromatography apparatus as claimed in claim 1 is characterized in that on the lower cover (14) of chromatographic column (3), the radially fluting of the moving phase outlet (17) that O-ring seals (22 ｀) is inboard, and the both sides of groove have the mill line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96202823 CN2263790Y (en) | 1996-02-13 | 1996-02-13 | Middle low pressure liquid phase chromatograph apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96202823 CN2263790Y (en) | 1996-02-13 | 1996-02-13 | Middle low pressure liquid phase chromatograph apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2263790Y true CN2263790Y (en) | 1997-10-01 |
Family
ID=33888622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96202823 Expired - Fee Related CN2263790Y (en) | 1996-02-13 | 1996-02-13 | Middle low pressure liquid phase chromatograph apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2263790Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103191586A (en) * | 2013-04-23 | 2013-07-10 | 陈浩达 | Chromatographic column assembly |
| CN106415263A (en) * | 2014-05-15 | 2017-02-15 | 株式会社岛津制作所 | Ferrule container, and ferrule container containing ferrule |
| CN111257596A (en) * | 2020-02-25 | 2020-06-09 | 西南交通大学 | Scanning probe microscope narrow and small experiment chamber environment atmosphere accurate control device |
-
1996
- 1996-02-13 CN CN 96202823 patent/CN2263790Y/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103191586A (en) * | 2013-04-23 | 2013-07-10 | 陈浩达 | Chromatographic column assembly |
| CN106415263A (en) * | 2014-05-15 | 2017-02-15 | 株式会社岛津制作所 | Ferrule container, and ferrule container containing ferrule |
| CN106415263B (en) * | 2014-05-15 | 2018-06-12 | 株式会社岛津制作所 | Pipe sleeve container and the pipe sleeve container for being incorporated with pipe sleeve |
| CN111257596A (en) * | 2020-02-25 | 2020-06-09 | 西南交通大学 | Scanning probe microscope narrow and small experiment chamber environment atmosphere accurate control device |
| CN111257596B (en) * | 2020-02-25 | 2021-09-14 | 西南交通大学 | Scanning probe microscope narrow and small experiment chamber environment atmosphere accurate control device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |