CN221351495U - Incubation and detection device for microporous biochip or microporous enzyme-labeled strip - Google Patents
Incubation and detection device for microporous biochip or microporous enzyme-labeled strip Download PDFInfo
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- CN221351495U CN221351495U CN202322837585.XU CN202322837585U CN221351495U CN 221351495 U CN221351495 U CN 221351495U CN 202322837585 U CN202322837585 U CN 202322837585U CN 221351495 U CN221351495 U CN 221351495U
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- microporous
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- enzyme
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- 238000001514 detection method Methods 0.000 title claims abstract description 86
- 238000000018 DNA microarray Methods 0.000 title claims abstract description 41
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 34
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 34
- 238000011534 incubation Methods 0.000 title claims abstract description 27
- 238000005485 electric heating Methods 0.000 claims abstract description 17
- 238000009413 insulation Methods 0.000 claims description 13
- 238000004321 preservation Methods 0.000 claims description 4
- 238000002965 ELISA Methods 0.000 abstract description 10
- 238000002474 experimental method Methods 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000002493 microarray Methods 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012742 biochemical analysis Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Abstract
The utility model discloses an incubation and detection device for a microporous biochip or microporous enzyme-labeled strip, which comprises a machine body, a touch screen and a porous adapter for placing the microporous biochip or microporous enzyme-labeled strip, wherein the touch screen is arranged on the machine body, an electric heating base is arranged at the top end of the machine body, and the porous adapter is arranged at the top end of the electric heating base during incubation; the detection cabin of the machine body is internally provided with a detection component for detecting the microporous biochip or microporous enzyme-labeled strip, the detection component comprises a detection tray and a camera for shooting the microporous biochip or microporous enzyme-labeled strip, and the porous adapter is spliced with the detection tray and positioned below the camera during detection. The temperature control incubation and detection functions are integrated on the same machine body, and when related experiments and detection are carried out, the microporous biochip or microporous ELISA plate strip does not need to be transferred in an incubation instrument and an analyzer, so that the device has a compact integral structure, small volume and convenient carrying.
Description
Technical Field
The utility model relates to an incubation and detection device, in particular to an incubation and detection device for a microporous biochip or a microporous enzyme-labeled strip.
Background
The microarray biochip and the ELISA can be widely applied in the fields of drug research and development, screening, life science research, medical examination, food detection and the like. Microporous elisa strips are used to detect and determine drug content, activity, affinity, interactions with target molecules, etc., by immobilizing specific biomolecules (e.g., enzymes, antigens, or antibodies) on a surface. The biochip integrates biochemical analysis process on the surface of the chip based on the specific interaction principle between biological molecules, so as to realize the high-flux fast detection of medicine, DNA, RNA, polypeptide, protein and other biological components.
The basic detection process of the ELISA adsorption test and the microarray biochip based on the microporous ELISA plate comprises the steps of sample adding, sample temperature control incubation, washing, substrate color development, data reading and the like, an incubation instrument and an analyzer are needed in the related experiments, the microporous ELISA plate or the microporous biochip is needed to be transferred between the incubation instrument and the analyzer in the test and detection processes, the actual test and detection operation are inconvenient, and the incubation instrument and the analyzer are large in size and are not suitable for small-sized laboratories.
Disclosure of utility model
The utility model aims to: the utility model aims to provide an incubation and detection device of a microporous biochip or microporous enzyme-labeled strip with two-in-one temperature control incubation and detection functions.
The technical scheme is as follows: the utility model relates to an incubation and detection device for a microporous biochip or microporous enzyme-labeled strip, which comprises a machine body, a touch screen and a porous adapter for placing the microporous biochip or microporous enzyme-labeled strip, wherein the touch screen is arranged on the machine body, an electric heating base is arranged at the top end of the machine body, and the porous adapter is arranged at the top end of the electric heating base during incubation; the detection cabin of the machine body is internally provided with a detection assembly for detecting the microporous biochip or the microporous enzyme-labeled strip, the detection assembly comprises a detection tray and a camera for shooting the microporous biochip or the microporous enzyme-labeled strip, the porous adapter is inserted into the detection tray and positioned below the camera during detection, and the electric heating base and the camera are respectively and electrically connected with the touch screen.
Further, the top end of the electric heating base is connected with a heat insulation sleeve, and the porous adapter is spliced with the heat insulation sleeve.
Further, the top of organism rotates and is connected with the heat preservation lid, the top at the electrical heating base is covered when the heat preservation lid is closed.
Further, gaps which are convenient for taking the porous adapter are formed in two sides of the heat insulation sleeve.
Further, the inner wall of the detection cabin of the machine body is connected with an LED backlight base for auxiliary detection, and the LED backlight base is positioned under the camera.
Further, the connecting frame is installed on the top of LED base in a poor light, the camera is connected with the connecting frame.
Further, the inner wall of the detection cabin of the machine body is connected with a support guide seat, and the detection tray is slidably connected to the top end of the support guide seat.
Further, the motor is installed to the detection cabin inner wall of organism, the output shaft fixedly connected with gear of motor, the tooth's socket of being connected with the gear engagement has been seted up to the bottom of detecting the tray, and the motor drive detects the top removal of tray at the support guide holder.
Further, a detection cabin door is fixedly connected to the side face of the detection tray.
Further, the LED backlight base and the motor are respectively and electrically connected with the touch screen.
The beneficial effects are that: compared with the prior art, the utility model has the following advantages: the temperature control incubation and detection functions are integrated on the same machine body, the same machine body can meet the test and detection requirements, the actual operation is convenient, the microporous biochip or microporous enzyme label plate strip does not need to be transferred in an incubation instrument and an analyzer during the actual operation, and the time required by the test and detection can be effectively reduced; the temperature control incubation and detection functions are integrated in the same machine body, so that the structural compactness of the equipment can be improved, and the device is small in size and convenient to carry.
Drawings
Fig. 1 is a schematic structural view of the present utility model.
Fig. 2 is a schematic diagram of another embodiment of the present utility model.
FIG. 3 is a schematic view of the structure of the electrically heated base and insulating sleeve of the present utility model.
Fig. 4 is a schematic structural diagram of a detection assembly according to the present utility model.
Fig. 5 is a schematic structural view of the detection tray of the present utility model.
Fig. 6 is a schematic structural diagram of an LED backlight chassis and a connection frame according to the present utility model.
Fig. 7 is a schematic structural view of a supporting guide seat according to the present utility model.
Detailed Description
The technical scheme of the utility model is further described below with reference to the accompanying drawings.
As shown in fig. 1 to 7, the incubation and detection device for the microporous biochip or microporous enzyme-labeled strip comprises a machine body 1, wherein a power supply connector 2, a USB (universal serial bus) plug connector 3, a touch screen 4 and a power switch 5 are fixedly arranged on the shell of the machine body 1, the device can be powered through the power supply connector 2 when in use, and detected data and pictures are transmitted to corresponding software for analysis through the USB plug connector 3 and a data line; the top of the machine body 1 is provided with a groove, the electric heating base 6 is fixedly arranged in the groove, the top of the electric heating base 6 is connected with the heat insulation sleeve 7, the heat insulation sleeve 7 is also positioned in the groove, the top of the machine body 1 is rotatably provided with the heat insulation cover 8, and when the temperature control is performed, the heat insulation cover 8 is closed and covers the upper part of the heat insulation sleeve 7, so that heat loss can be reduced, and a constant-temperature incubation environment is provided; the incubation and detection device of micropore biochip or micropore ELISA plate strip still includes porous adapter 10, and during the use, put into porous adapter 10 with micropore biochip or micropore ELISA plate strip on, the both sides of insulating sheath 7 all are provided with the breach of being convenient for take porous adapter 10, and the recess of organism 1 cooperates with the breach of porous adapter 10, makes things convenient for the operator to install or dismantle porous adapter 10 on insulating sheath 7, wherein insulating sheath 7 can reduce the loss of heat when electric heating base 6 opens on the one hand, on the other hand can peg graft fixed porous adapter 10, stability when reinforcing incubation.
A cabin door 9 matched with the detection cabin of the machine body 1 is arranged at the opening of the detection cabin, a detection assembly for detecting the microporous biochip or microporous enzyme label strip is arranged in the detection cabin, the detection assembly comprises a detection tray 12 and a camera 11 for shooting the microporous biochip or microporous enzyme label strip, the detection tray 12 is provided with a through groove for plugging the porous adapter 10, the porous adapter 10 is detachably connected with the shell of the detection tray 12, the porous adapter 10 is plugged with the detection tray 12 during detection, the porous adapter 10 is positioned below the camera 11, and the cabin door 9 is fixedly arranged on one side of the detection tray 12; the inner wall of the detection cabin of the machine body 1 is connected with an LED backlight base 13 for auxiliary detection, the LED backlight base 13 is positioned under the camera 11, and an LED lamp of the LED backlight base 13 irradiates the microporous ELISA plate bar from the lower part during detection, so that a better shooting environment can be provided for shooting of the camera 11, wherein a connecting frame 14 is arranged at the top end of the LED backlight base 13, and the camera 11 is connected with the connecting frame 14; the inner wall of a detection cabin of the machine body 1 is connected with a support guide seat 15, a detection tray 12 is slidably connected to the top end of the support guide seat 15, a bump bar is integrally formed at the top end of the support guide seat 15, a guide groove matched with the bump bar is integrally formed at the bottom end of the detection tray 12, the bump bar of the support guide seat 15 and the guide groove of the detection tray 12 can enhance the stability of the detection tray 12 when moving relative to the support guide seat 15, the detection tray 12 slides at the top end of the support guide seat 15, the porous adapter 10 carries a microporous biochip or a microporous ELISA plate bar to move relative to the camera 11, so that the camera 11 can comprehensively shoot the microporous biochip or the microporous ELISA plate bar, preferably, a motor 16 is mounted at the inner wall of the detection cabin of the machine body 1, a gear is fixedly connected to an output shaft of the motor 16, a tooth groove connected with the gear in a meshed manner is formed at the bottom end of the detection tray 12, the motor 16 is a forward and backward stepping motor, and the detection tray 12 can automatically move at the top end of the support guide seat 15 when the motor 16 is started; the LED backlight base 13, the supporting guide seat 15, and the motor 16 are sequentially arranged in the direction from the cabin door 9 to the inside of the detection cabin, and the electric heating base 6, the camera 11, the LED backlight base 13, and the motor 16 are respectively electrically connected with the touch screen 4, and the electric heating base 6, the camera 11, the LED backlight base 13, and the motor 16 can be controlled by the touch screen 4 in actual use.
The working process comprises the following steps: when the temperature control is incubated, the microporous biochip or microporous enzyme label plate strip is placed on the porous adapter 10, then the porous adapter 10 is inserted on the heat insulation sleeve 7, the heat insulation cover 8 is closed, the incubation temperature and incubation time of the electric heating base 6 are controlled through the touch screen 4, after the temperature control incubation is finished, the motor 16 is controlled to operate positively through the touch screen 4, the motor 16 is started to drive the gear to rotate, the gear drives the detection tray 12 meshed with the motor to move outwards, the cabin door 9 is further opened, the detection tray 12 moves to the outside of the detection cabin, then the porous adapter 10 with the microporous biochip or microporous enzyme label plate strip is placed on the detection tray 12, then the motor 16 operates reversely, the detection tray 12 moves towards the inside of the detection cabin, the microporous biochip or microporous enzyme label plate strip passes through the lower part of the camera 11 in sequence, the camera 11 shoots and detects the microporous biochip or microporous enzyme label plate strip, and an image is obtained.
Claims (10)
1. The device for incubating and detecting the microporous biochip or microporous enzyme-labeled strip comprises a machine body (1), and is characterized in that: the multifunctional biological chip incubator further comprises a touch screen (4) and a porous adapter (10) for placing a microporous biological chip or a microporous enzyme label strip, wherein the touch screen (4) is arranged on the incubator body (1), the top end of the incubator body (1) is provided with an electric heating base (6), and the porous adapter (10) is placed at the top end of the electric heating base (6) during incubation; the detection cabin of the machine body (1) is internally provided with a detection assembly for detecting the microporous biochip or the microporous enzyme label strip, the detection assembly comprises a detection tray (12) and a camera (11) for shooting the microporous biochip or the microporous enzyme label strip, the porous adapter (10) is inserted with the detection tray (12) and positioned below the camera (11) during detection, and the electric heating base (6) and the camera (11) are respectively electrically connected with the touch screen (4).
2. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 1, wherein: the top end of the electric heating base (6) is connected with a heat insulation sleeve (7), and the porous adapter (10) is spliced with the heat insulation sleeve (7).
3. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 1 or 2, wherein: the top end of the machine body (1) is rotatably connected with a heat preservation cover (8), and the heat preservation cover (8) covers the upper part of the electric heating base (6) when being closed.
4. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 2, wherein: both sides of the heat insulation sleeve (7) are provided with notches which are convenient for taking the porous adapter (10).
5. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 1, wherein: the LED backlight base (13) for assisting detection is connected to the inner wall of the detection cabin of the machine body (1), and the LED backlight base (13) is located under the camera (11).
6. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 5, wherein: the top end of the LED backlight base (13) is provided with a connecting frame (14), and the camera (11) is connected with the connecting frame (14).
7. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 5 or 6, wherein: the inner wall of the detection cabin of the machine body (1) is connected with a support guide seat (15), and the detection tray (12) is slidably connected to the top end of the support guide seat (15).
8. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 7, wherein: the detection cabin inner wall of the machine body (1) is provided with a motor (16), an output shaft of the motor (16) is fixedly connected with a gear, and a tooth slot which is meshed with the gear is formed in the bottom end of the detection tray (12).
9. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 1, wherein: the side face of the detection tray (12) is fixedly connected with a detection cabin door (9).
10. The device for incubating and detecting a microporous biochip or microporous enzyme-labeled strip according to claim 8, wherein: the LED backlight base (13) and the motor (16) are respectively and electrically connected with the touch screen (4).
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221351495U true CN221351495U (en) | 2024-07-16 |
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