CN220730231U

CN220730231U - Full-automatic chemical luminescence analyzer

Info

Publication number: CN220730231U
Application number: CN202322409110.0U
Authority: CN
Inventors: 马江林; 叶翔
Original assignee: Shenzhen Shixin Medical Technology Co ltd
Current assignee: Shenzhen Shixin Medical Technology Co ltd
Priority date: 2023-09-05
Filing date: 2023-09-05
Publication date: 2024-04-05
Anticipated expiration: 2033-09-05

Abstract

The utility model discloses a full-automatic chemiluminescence analyzer, which comprises a rack; the automatic cup feeding system is used for storing and feeding the reaction cups; the cup conveying system is used for conveying the reaction cups of the automatic cup feeding system to the mixing system and conveying the reaction cups after being uniformly mixed in the mixing system to the incubation cleaning system; the automatic sample injection system is used for storing and carrying the sample tubes; the sample mixing system is used for mixing samples to be mixed in advance before adding the samples; the sample needle system is used for sucking and adding a reagent and a sample into a reaction cup of the uniformly mixing system; a reagent tray system for refrigerated storage of reagents; the mixing system is used for uniformly mixing the sample and the reagent in the reaction cup; the incubation and cleaning system is used for performing incubation operation and cleaning operation on the uniformly mixed substances in the reaction cup; and the photometry system is used for carrying out optical detection on the incubated substances. The utility model realizes the uniform mixing of the samples before adding the samples, does not need manual participation, and improves the detection efficiency.

Description

Full-automatic chemical luminescence analyzer

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a full-automatic chemiluminescence analyzer.

Background

The full-automatic chemiluminescence analyzer is an analyzer used in the clinical medicine field. A full-automatic chemiluminescence analyzer is a device for analyzing metal ions, fluorescent dyes, etc. in a substance. The method comprises the steps of exciting a sample to be detected by using an excitation light source, and measuring the intensity of fluorescent signals emitted by the sample to determine the content of various components in the sample to be detected. Chemiluminescent immunoassay is a non-radioactive immunoassay technology which has been rapidly developed in recent years, and the principle is that a chemiluminescent substance is utilized to amplify a signal, and the immunological binding process is directly measured by means of the luminous intensity of the chemiluminescent substance, so that the method has become one of important directions of immunological detection.

The chemiluminescent detection flow is complex, the less operators participate in the detection flow, the more accurate the detection result, and the faster the instrument test speed. In the existing full-automatic chemiluminescence analyzers, some samples are required to be mixed uniformly manually before being put on the analyzer, so that the detection efficiency is low.

Disclosure of Invention

The utility model mainly aims to provide a full-automatic chemiluminescence analyzer, which aims to solve the problem that in the existing full-automatic chemiluminescence analyzer, manual mixing is needed before some samples are put on the analyzer, so that the detection efficiency is low.

In order to achieve the above purpose, the utility model provides a full-automatic chemiluminescence analyzer, which comprises a frame, an automatic cup feeding system, a cup conveying system, an automatic sample feeding system, a sample needle system, a reagent tray system, a mixing system, an incubation cleaning system, a photometry system and a sample mixing system, wherein the automatic cup feeding system, the cup conveying system, the automatic sample feeding system, the sample needle system, the reagent tray system, the mixing system, the incubation cleaning system and the sample mixing system are arranged on the frame; the automatic cup feeding system is used for storing and feeding the reaction cups; the cup conveying system is movably arranged at the periphery of the incubation cleaning system and is used for conveying the reaction cups of the automatic cup feeding system to the mixing system and conveying the reaction cups which are uniformly mixed in the mixing system to the incubation cleaning system; the automatic sample injection system is arranged at one side of the sample needle system and used for storing and carrying sample tubes, and an emergency sample tube feeding device used for carrying emergency samples is arranged on the automatic sample injection system; the sample mixing system is arranged on the automatic sample injection system and is used for mixing samples to be mixed in advance before sample addition; the sample needle system is movably arranged between the mixing system and the automatic sample injection system and is used for sucking and adding a reagent into a reaction cup of the mixing system; the reagent disk system is arranged at one side of the sample needle system and is used for refrigerating and storing reagents; the mixing system is arranged at one side of the cup conveying system and is used for mixing the sample and the reagent in the reaction cup, and a mixer for mixing is arranged on the mixing system; the incubation and cleaning system is arranged at one side of the automatic cup feeding system and is used for performing incubation operation and cleaning operation on the uniformly mixed substances in the reaction cup; the photometry system is arranged at the periphery of the incubation cleaning system and is used for carrying out optical detection on the incubated substances.

In one embodiment, the sample mixing system comprises a clamping jaw used for grabbing the sample tube, a motor screw rod linear module used for driving the clamping jaw to move up and down, a mixing motor used for driving the clamping jaw to rotate and mix the sample tube, and a sample tube pushing motor used for pushing the sample tube out of the clamping jaw, wherein a driving end of the motor screw rod linear module is connected with a mounting plate, the mixing motor and the sample tube pushing motor are mounted on the mounting plate, and the clamping jaw is connected with the mixing motor and the driving end of the sample tube pushing motor.

In one embodiment, the sample needle system comprises a sampling needle, a sample arm and a first transmission mechanism, wherein the sampling needle is arranged on the sample arm, the first transmission mechanism is arranged at the bottom of the sample arm, and the first transmission mechanism drives the sample arm to drive the sampling needle to move to the automatic sampling system, the mixing system or the reagent disk system.

In one embodiment, the automatic sample feeding system further comprises a sample tube feeding level for feeding, a sample tube detection position for detecting the sample tube, a sample tube discharging level for discharging, a sample frame for loading the sample tube and a plurality of driving motors for driving the sample frame to move, wherein the driving motors drive the sample frame to sequentially pass through the sample tube detection position, the emergency sample tube feeding device is arranged on one side of the sample tube detection position, and the sample tube detection position is located on the movement track of the sampling needle.

In one embodiment, the emergency sample tube feeding device comprises an emergency sample tube rack for storing emergency sample tubes and an emergency driver for driving the emergency sample tube rack to move, an emergency position is arranged on the automatic sample injection system on the motion track of the sampling needle, and the emergency sample tube rack enters or leaves the emergency position through the emergency driver.

In one embodiment, the incubation and cleaning system includes a needle cleaning basin for cleaning the sampling needle, the needle cleaning basin being disposed on a periphery of the incubation and cleaning system proximate the sample needle system, the needle cleaning basin being located on a motion trajectory of the sampling needle.

In one embodiment, the incubation and cleaning system further comprises an incubation tray for incubating samples, a cleaning tray for cleaning the reaction cups, an incubation tray driver for driving the incubation tray to rotate, and a cleaning tray driver for driving the cleaning tray to rotate, wherein the cleaning tray is arranged above the incubation tray, a cup placing position for placing the cleaning tray for incubating the reaction cups and a cup placing position for placing the reaction cups to be incubated are formed in the cleaning tray, and a liquid inlet component for cleaning is arranged above the cleaning tray.

In one embodiment, the automatic cup feeding system comprises a storage bin for storing the reaction cups and a cup rolling chain for conveying the reaction cups, the storage bin is arranged on one side of the cup rolling chain, a cup feeding opening is formed in the bottom of the storage bin and communicated with the cup rolling chain, and the cup rolling chain drives the reaction cups to move to the periphery of the incubation cleaning system.

In one embodiment, the cup transporting system comprises a rotating arm, a second transmission mechanism for driving the rotating arm to rotate and a clamping piece for carrying the reaction cup, wherein the rotating arm rotates to drive the clamping piece to clamp the reaction cup to reciprocate between the incubation cleaning system and the mixing system.

In one embodiment, the reagent disk system comprises a reagent box for loading reagent, a reagent disk for driving the reagent box to rotate, a reagent pot for installing the reagent disk, a rotating motor for driving the reagent disk to rotate and a refrigerating air duct for reducing the temperature of the reagent, wherein the reagent disk is connected with the driving end of the rotating motor.

The utility model has the beneficial effects that:

according to the utility model, the sample mixing system is arranged on the automatic sample feeding system in the full-automatic chemiluminescence analyzer, and the sample mixing system can mix the sample tubes on the automatic sample feeding system uniformly, so that the requirement that part of test items need to mix samples before adding the samples is met, the whole test flow is automatic, manual participation is not needed, and the detection efficiency is improved.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of the structure of a full-automatic chemiluminescence analyzer of the present utility model;

FIG. 2 is a schematic view of another angle of the full-automatic chemiluminescence analyzer;

FIG. 3 is a top view of the full-automatic chemiluminescence analyzer of the present utility model;

FIG. 4 is a schematic diagram of a sample mixing system according to the present utility model;

FIG. 5 is a schematic diagram of the structure of the incubation and cleaning system of the present utility model;

FIG. 6 is a schematic view of an alternative view of the incubation and cleaning system of the present utility model;

FIG. 7 is a schematic diagram of the structure of the reagent disk system of the present utility model;

FIG. 8 is a cross-sectional view of a reagent disk system of the present utility model;

FIG. 9 is a schematic diagram of an automatic sample injection system according to the present utility model

Fig. 10 is a schematic structural view of the mixing system of the present utility model.

Reference numerals illustrate:

a frame 1; an automatic cup feeding system 2; a reserve bin 21; a cup winding chain 22; a cup transporting system 3; a rotating arm 31; a second transmission mechanism 32; a clamp 33; a mixing system 4; a mixer 41; an automatic sample injection system 5; an emergency sample tube feeding device 51; emergency sample tube rack 511; emergency driver 512; emergency department 513; a sample blending system 52; clamping jaw 521; a motor lead screw linear module 522; a synchronous pulley 523; a blending motor 524; a push sample tube motor 525; sample tube loading level 53; sample tube detection bit 54; sample tube blanking level 55; a sample holder 56; a drive motor 57; a sample needle system 6; a sampling needle 61; a sample arm 62; a first transmission 63; a reagent tray system 7; a kit 71; a reagent rotor 72; a reagent pot 73; a rotating motor 74; a cooling air duct 75; a fan 75a; peltier cooling tab 75b; a heat sink 75c; an incubation and washing system 8; a needle cleaning bath 81; an incubation tray 82; a cleaning tray 83; an incubation plate drive 84; a cleaning disk drive 85; the cleaning tray cup placement position 86; incubation tray cup placement 87; a lifting guide shaft 88a; cleaning the lifting motor 88b; a purge cup motor 88c; cleaning the mixing motor 88d; injecting an excitation liquid A site 88e; injecting an excitation liquid B site 88f; a first order filling level 88g; a first-order pumping level 88h; second order filling level 88i; second order pumping level 88j; third order fill level 88k; a third-order pumping level 88l; a waste liquid pumping level 88n; a waste liquid pumping level lifting motor 88m; and a photometry system 9.

The achievement of the objects, functional features and advantages of the present utility model will be further described with reference to the accompanying drawings, in conjunction with the embodiments.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It should be noted that, if directional indications (such as up, down, left, right, front, and rear … …) are included in the embodiments of the present utility model, the directional indications are merely used to explain the relative positional relationship, movement conditions, etc. between the components in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are correspondingly changed.

In addition, if there is a description of "first", "second", etc. in the embodiments of the present utility model, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, if the meaning of "and/or" is presented throughout this document, it is intended to include three schemes in parallel, taking "a and/or B" as an example, including a scheme, or B scheme, or a scheme where a and B meet simultaneously. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present utility model.

Referring to fig. 1, 2, 3 and 10, an embodiment of the present utility model provides a full-automatic luminescence analyzer, which comprises a frame 1, an automatic cup feeding system, a cup transporting system 3, an automatic sample feeding system 5, a sample needle system 6, a reagent disk system 7, a mixing system 4, an incubation cleaning system 8, a photometry system 9 and a sample mixing system 52, wherein the automatic cup feeding system, the cup transporting system 3, the automatic sample feeding system 5, the sample needle system 6, the reagent disk system 7, the mixing system 4, the incubation cleaning system 8, the photometry system 9 and the sample mixing system 52 are installed on the frame 1; the automatic cup feeding system is used for storing and feeding the reaction cups; the cup conveying system 3 is movably arranged at the periphery of the incubation cleaning system 8 and is used for conveying the reaction cups of the automatic cup feeding system to the mixing system 4 and conveying the reaction cups which are uniformly mixed in the mixing system 4 to the incubation cleaning system 8; the automatic sample injection system 5 is arranged at one side of the sample needle system 6 and is used for storing and carrying sample tubes, and an emergency sample tube feeding device 51 used for carrying emergency samples is arranged on the automatic sample injection system 5; the sample mixing system 52 is arranged on the automatic sample injection system 5 and is used for mixing samples to be mixed in advance before sample addition; the sample needle system 6 is movably arranged between the mixing system 4 and the automatic sample injection system 5 and is used for sucking and adding a reagent and the sample into a reaction cup of the mixing system 4; the reagent disk system 7 is arranged on one side of the sample needle system 6 and is used for refrigerating and storing reagents; the mixing system 4 is arranged at one side of the cup transporting system 3 and is used for mixing the sample and the reagent in the reaction cup, and a mixer 41 for mixing is arranged on the mixing system 4; the incubation and cleaning system 8 is arranged at one side of the automatic cup feeding system and is used for performing incubation operation and cleaning operation on the uniformly mixed substances in the reaction cup; the photometry system 9 is arranged at the periphery of the incubation cleaning system 8 and is used for carrying out optical detection on the substances after incubation.

Specifically, in this embodiment, the present automatic chemiluminescence analyzer is mainly divided into the automatic cup feeding system, the cup transporting system 3, the mixing system 4, the automatic sample feeding system 5, the sample needle system 6, the reagent tray system 7, the incubation and cleaning system 8, and the photometry system 9, where the systems cooperate with each other to complete a more complex test procedure, firstly, the automatic cup feeding system provides the reaction cup, the cup transporting system 3 transports the reaction cup to the mixing device 41 of the mixing system 4, the sample needle system 6 sucks the sample of the sample tube on the automatic sample feeding system 5 and spits the sample into the reaction cup, the sample needle system 6 spits the corresponding reagent from the reagent tray system 7 into the reaction cup, then, the mixing system 4 mixes the reaction cup with the added sample and reagent, the cup transporting system 3 places the reaction cup after the mixing is completed in the incubation and cleaning system 8, and finally, the sample needle system 6 sucks the sample tube on the automatic sample feeding system 5 and spits the sample tube into the reaction cup, and the automatic chemiluminescence analyzer detects the reaction cup at any time, and the automatic chemiluminescence analyzer is fast in the detection speed; and set up on the autoinjection system 5 sample mixing system 52, sample mixing system 52 can be used to realize the demand that partial test item need carry out the mixing to the sample before adding the sample, has reduced artifical participation, has further improved detection efficiency. For example, if the tip blood after standing is required to be detected, an operator can directly put a sample tube containing the tip blood sample on the automatic sample injection system 5, and the sample mixing system 52 mixes the tip blood sample and returns the tip blood sample to the automatic sample injection system 5, so that the mixing of the sample before sample addition is completed, the mixing of the sample before sample addition is not required, the mixing of the sample before sample addition is required to be carried out on the automatic sample injection system 5, the manual participation is reduced, the time and labor are saved, the detection efficiency is improved, the automation degree of the full-automatic chemiluminescence analyzer is further improved, and the pollution is reduced.

In another embodiment, the full-automatic chemiluminescence analyzer further comprises a waste cup treatment system for treating the reaction cup after the completion of photometry, wherein the waste cup treatment system can be arranged on one side of the cup conveying system 3 away from the incubation and cleaning system 8, the cup conveying system 3 conveys the reaction cup after the completion of photometry into the waste cup treatment system, and the waste cup treatment system can pump out liquid in the reaction cup and treat and recycle the reaction cup; the full-automatic chemiluminescence analyzer further comprises a power supply system for supplying electric energy to the whole instrument and a control system for controlling the operation of the instrument, wherein the control system is electrically connected with each system in the full-automatic chemiluminescence analyzer through a PCB card and software respectively, so that the full-automatic chemiluminescence analyzer can normally operate.

According to the utility model, the sample mixing system 52 is arranged on the automatic sample injection system 5 in the full-automatic chemiluminescence analyzer, and the sample mixing system 52 can mix the sample tubes on the automatic sample injection system 5 uniformly, so that the requirement that part of test items need to mix samples before adding the samples is met, the whole test flow is automatic, manual participation is not needed, and the detection efficiency is improved.

Referring to fig. 4, the sample mixing system 52 includes a clamping jaw 521 for grabbing the sample tube, a motor screw rod linear module 522 for driving the clamping jaw 521 to move up and down, a mixing motor 524 for driving the clamping jaw 521 to rotate and mix, and a sample tube pushing motor 525 for pushing the sample tube out of the clamping jaw 521, wherein a driving end of the motor screw rod linear module 522 is connected with a mounting plate, the mixing motor 524 and the sample tube pushing motor 525 are mounted on the mounting plate, and the clamping jaw 521 is connected with the mixing motor 524 and the driving end of the sample tube pushing motor 525.

Specifically, in this embodiment, some test items need to mix samples before adding samples, when a sample tube on the automatic sampling system 5 moves to the vicinity of the sample mixing system 52, the motor lead screw linear module 522 drives the clamping jaw 521 to move downward, the inner wall of one end of the clamping jaw 521 facing the sample tube is convexly provided with a protrusion clamped with the sample tube, so that the clamping jaw 521 grabs the sample tube, the motor lead screw linear module 522 drives the clamping jaw 521 and the sample tube to rise, at this time, the mixing motor 524 drives the clamping jaw 521 to rotate through the synchronous pulley 523 mechanism, so as to realize mixing samples in the sample tube, after the mixing operation is completed, the motor lead screw linear module 522 moves downward, and the sample tube pushing motor drives the sample tube to withdraw from the clamping jaw 521, thus completing sample mixing, avoiding the human intervention, individual difference of manual operation, non-uniform operation, non-uniformity of operation and the like, improving the accuracy of luminescence analysis and accuracy of luminescence detection are improved.

Referring to fig. 2 and 3, the sample needle system 6 includes a sampling needle 61, a sample arm 62, and a first transmission mechanism 63, where the sampling needle 61 is disposed on the sample arm 62, the first transmission mechanism 63 is disposed at the bottom of the sample arm 62, and the first transmission mechanism 63 drives the sample arm 62 to drive the sampling needle 61 to move to the automatic sampling system 5, the incubation cleaning system 8, the mixing system 4, or the reagent disk system 7.

In particular, a transmission is a component or mechanism that transfers power from one part of a machine to another, causing the machine or machine component to move or operate, known as a transmission. In this embodiment, the transmission mechanism is a structure in which the gear drives the synchronous belt to move, the transmission mechanism drives the sampling needle 61 to rotate in all directions by three hundred sixty degrees so that the sampling needle intersects with surrounding systems, in addition, a motor for driving the sample arm 62 to move up and down and a scanner for scanning sample information are further arranged on the sample needle system 6, and the sampling needle 61 can realize functions of spitting and sucking of samples, liquid level detection and the like through up and down movement.

Referring to fig. 1 and 9, the automatic sample feeding system 5 further includes a sample tube feeding level 53 for feeding, a sample tube discharging level 54 for detecting a sample tube, a sample tube discharging level 55 for discharging, a sample frame 56 for loading the sample tube, and a plurality of driving motors 57 for driving the sample frame 56 to move, wherein the driving motors 57 drive the sample frame 56 to sequentially pass through the sample tube discharging level 54, the emergency sample tube feeding device 51 is mounted on one side of the sample tube discharging level 54, and the sample tube discharging level 54 is located on the movement track of the sampling needle 61. Specifically, the sample rack 56 is first moved horizontally and longitudinally to a position in the same line as the sample tube discharging position 54 in the sample tube feeding area, then moved horizontally and laterally into the sample tube discharging position 54, finally leaves the sample tube discharging position 54, and enters the sample tube discharging position 55, and in this embodiment, the sample tube feeding position 53 and the sample tube discharging position 55 are symmetrically arranged.

Referring to fig. 1 and 9, the emergency sample tube feeding device 51 includes an emergency sample tube rack 511 for storing emergency sample tubes, and an emergency driver 512 for driving the emergency sample tube rack 511 to move, an emergency position 513 is disposed on the motion track of the sampling needle 61 on the automatic sampling system 5, and the emergency sample tube rack 511 enters or leaves the emergency position 513 through the emergency driver 512. Specifically, the movement track of the sampling needle 61 intersects with the emergency treatment site 513, so that the sampling needle 61 can conveniently transport the emergency treatment sample in the emergency treatment sample tube to the blending system 4 so as to complete the subsequent detection operation.

Referring to fig. 5 and 6, the incubation and washing system 8 includes a needle washing basin 81 for washing the sampling needle 61, the needle washing basin 81 being disposed on the periphery of the incubation and washing system 8 near the sample needle system 6, the needle washing basin 81 being located on the movement track of the sampling needle 61. Specifically, the sampling needle 61 is cleaned by the needle cleaning tank 81 after each sample or reagent addition, so as to avoid cross contamination.

Referring to fig. 5 and 6, the incubation and cleaning system 8 further includes an incubation tray 82 for incubating samples, a cleaning tray 83 for cleaning the reaction cups, an incubation tray driver 84 for driving the incubation tray 82 to rotate, and a cleaning tray driver 85 for driving the cleaning tray 83 to rotate, the cleaning tray 83 is disposed above the incubation tray 82, a cleaning tray placement position 86 for placing the reaction cups after incubation and an incubation tray placement position 87 for placing the reaction cups to be incubated are formed on the cleaning tray 83, and a liquid inlet assembly for performing a cleaning operation is disposed above the cleaning tray 83.

Specifically, in this embodiment, the incubation and cleaning system 8 implements incubation of the sample, the incubation temperature may be controlled at 37±0.5 ℃, so as to implement third-order cleaning of the sample, the incubation plate 82 and the cleaning plate 83 are coaxially distributed, the incubation driver is used for driving the incubation plate 82 to rotate, and the cleaning driver is used for driving the cleaning plate 83 to rotate, so as to drive the reaction cup on the cleaning plate 83 to the liquid inlet assembly to perform cleaning operation, substrate filling operation and mixing operation. The cup transporting system 3 places the reaction cup added with the sample and the reagent from the cup placing position 87 of the incubation plate into the incubation plate 82 for incubation, and after the reaction cup is incubated for a sufficient time, the cup transporting system 3 transports the reaction cup to the cup placing position 86 of the cleaning plate, and the reaction cup is sequentially cleaned by a second step and a third step; the cup transporting system 3 transports the cleaned reaction cup to the photometry system 9 on the outer ring of the incubation plate 82, and data is obtained by photometry of the photometry module.

More specifically, the liquid inlet assembly comprises a lifting guide shaft 88a for providing a lifting direction for a cleaning position, a cleaning lifting motor 88B for driving the cleaning position to lift, a cleaning cup removing motor 88c for separating the cleaning position from the reaction cup, a cleaning mixing motor 88d, an injection excitation liquid A position 88e, an injection excitation liquid B position 88f and a cleaning position, wherein the cleaning position is divided into a first-order injection liquid level 88g, a first-order liquid pumping level 88h, a second-order injection liquid level 88i, a second-order liquid pumping level 88j, a third-order injection liquid level 88k and a third-order liquid pumping level 88l, one side of the lifting guide shaft 88a is further provided with a waste liquid pumping level 88n for pumping waste liquid in the reaction cup after completion of photometry and a waste liquid pumping level lifting motor 88m for driving the waste liquid pumping level 88n to lift; the injection excitation liquid B site 88f is arranged above the photometry system 9, the excitation liquid A and the excitation liquid B can adapt to a luminescent reagent system of direct luminescent substances such as enzymatic luminescence and anchorage ester, and the like, photometry is carried out after a substrate is added, the photometry value of a sample after reaction is realized, and a test result is fed back through a control system. The process of the first-second third-order cleaning is as follows: the reaction cup is rotated to a first-order liquid injection level 88g to perform first-order liquid injection, then the reaction cup is rotated to a first-order liquid extraction level 88h to perform first-order liquid extraction, before the reaction cup is rotated to the first-order liquid extraction level 88h, magnetic beads in a magnet adsorption reagent are needed to pass through two hole sites, the first-order liquid extraction level 88h pumps away unadsorbed liquid, then the liquid is sequentially injected and adsorbed through a second-order liquid injection level 88i, the liquid is extracted through a second-order liquid extraction level 88j, the liquid is injected and adsorbed through a third-order liquid injection level 88k, and finally the liquid is extracted through a third-order liquid extraction level 88l, so that the cleaning operation is completed. The reaction cup is rotated to the position 88e for injecting the excitation liquid A, the reaction cup is transported to the photometry system 9 by the cup transporting system 3 at the moment, the excitation liquid B is injected, and the photon number is measured.

Referring to fig. 1 and 3, the automatic cup feeding system comprises a storage bin 21 for storing the reaction cups and a cup rolling chain 22 for conveying the reaction cups, wherein the storage bin 21 is arranged on one side of the cup rolling chain 22, a cup feeding opening is formed in the bottom of the storage bin 21 and is communicated with the cup rolling chain 22, and the cup rolling chain 22 drives the reaction cups to move to the periphery of the incubation cleaning system 8. Specifically, the reaction cups in the storage bin 21 enter the cup rolling chain 22 through the cup inlet, and a plurality of slots for placing the reaction cups are arranged on the cup rolling chain 22, so that the cup rolling chain 22 can simultaneously convey one or more reaction cups to the periphery of the incubation and cleaning system 8, and a new reaction cup is provided for the whole detection process.

Referring to fig. 1 and 3, the cup transporting system 3 includes a rotating arm 31, a second transmission mechanism 32 for driving the rotating arm 31 to rotate, and a clamping member 33 for carrying the reaction cup, where the rotating arm 31 rotates to drive the clamping member 33 to clamp the reaction cup to reciprocate between the incubation and cleaning system 8 and the mixing system 4. Specifically, in the present embodiment, the second transmission mechanism 32 and the first transmission mechanism 63 are configured as similar mechanisms, which have the same functions, and are not described here; the operation system and the sample needle system 6 are similar in design, except that the clamping piece 33 of the cup transporting system 3 is used for clamping the reaction cup, and the sampling needle 61 in the sample needle system 6 is used for sucking samples or reagents, so that the cup transporting system 3 and the sample needle system 6 are in separate work and cooperation, the whole detection process is simplified, and the detection efficiency is improved.

Referring to fig. 7 and 8, the reagent disk system 7 includes a reagent cassette 71 for loading a reagent, a reagent rotor 72 for driving the reagent cassette 71 to rotate, a reagent pot 73 for mounting the reagent rotor 72, a rotary motor 74 for driving the reagent rotor 72 to rotate, and a cooling air duct 75 for reducing the temperature of the reagent, and the reagent rotor 72 is connected to a driving end of the rotary motor 74.

Specifically, in this embodiment, the reagent disk system 7 may implement refrigerated storage of the reagent and mixing of the magnetic bead reagent, so that the magnetic beads are uniformly distributed in the reagent to ensure the performance of the magnetic bead reagent, and the magnetic bead reagent is mixed uniformly, in which the rotating motor 74 drives the reagent disk to rotate by setting the synchronous pulley 523, so as to drive mixing of the magnetic bead reagent; the reagent is added with magnetic beads which are particles with specific active groups on the surface, uniform size, sphericity, superparamagnetism and protective shell. The magnetic beads show magnetic force in the presence of an external magnetic field to gather, and lose the magnetic force to disperse in the absence of the magnetic field. The method comprises the steps of combining active substances such as antigen/antibody and the like with active groups on the surface of the magnetic beads to coat the active substances on the surface of the magnetic beads, incubating the object to be detected and the magnetic beads coated with the antigen/antibody under certain conditions during detection, combining the active substances and the magnetic beads through antigen-antibody reaction, adding an external magnetic field to generate magnetism to gather the active substances and the magnetic beads, performing washing operation, separating an antigen-antibody combined part from an unbound part, adding substances such as substrate liquid and the like, detecting emitted optical signals by using the photometry system 9, and analyzing the content of the antigen/antibody in the object to be detected. In order to make the reagent perform its function better, the reagent needs to be refrigerated and stored, so the reagent tray system 7 is provided with a refrigerating air duct 75, a fan 75a is arranged in the refrigerating air duct 75, the bottom of the reagent tray is provided with a peltier refrigerating sheet 75b, and the bottom of the peltier refrigerating sheet 75b is provided with a radiator 75c, so that the heat in the reagent tray is reduced, and the purpose of refrigerating and storing the reagent is achieved.

The foregoing description is only of the optional embodiments of the present utility model, and is not intended to limit the scope of the utility model, and all the equivalent structural changes made by the description of the present utility model and the accompanying drawings or the direct/indirect application in other related technical fields are included in the scope of the utility model.

Claims

1. The full-automatic chemiluminescence analyzer is characterized by comprising a rack, an automatic cup feeding system, a cup conveying system, an automatic sample feeding system, a sample needle system, a reagent disk system, a mixing system, an incubation cleaning system, a photometry system and a sample mixing system, wherein the automatic cup feeding system, the cup conveying system, the automatic sample feeding system, the sample needle system, the reagent disk system, the mixing system, the incubation cleaning system, the photometry system and the sample mixing system are arranged on the rack;

the automatic cup feeding system is used for storing and feeding the reaction cups;

the cup conveying system is movably arranged at the periphery of the incubation cleaning system and is used for conveying the reaction cups of the automatic cup feeding system to the mixing system and conveying the reaction cups which are uniformly mixed in the mixing system to the incubation cleaning system;

the automatic sample injection system is arranged at one side of the sample needle system and used for storing and carrying sample tubes, and an emergency sample tube feeding device used for carrying emergency samples is arranged on the automatic sample injection system;

the sample mixing system is arranged on the automatic sample injection system and is used for mixing samples to be mixed in advance before sample addition;

the sample needle system is movably arranged between the mixing system and the automatic sample injection system and is used for sucking and adding a reagent into a reaction cup of the mixing system;

the reagent disk system is arranged at one side of the sample needle system and is used for refrigerating and storing reagents;

the mixing system is arranged at one side of the cup conveying system and is used for mixing the sample and the reagent in the reaction cup, and a mixer for mixing is arranged on the mixing system;

the incubation and cleaning system is arranged at one side of the automatic cup feeding system and is used for performing incubation operation and cleaning operation on the uniformly mixed substances in the reaction cup;

the photometry system is arranged at the periphery of the incubation cleaning system and is used for carrying out optical detection on the incubated substances.

2. The full-automatic chemiluminescence analyzer of claim 1, wherein the sample mixing system comprises a clamping jaw for grabbing the sample tube, a motor screw rod linear module for driving the clamping jaw to move up and down, a mixing motor for driving the clamping jaw to rotate and mix, and a sample tube pushing motor for pushing the sample tube out of the clamping jaw, wherein the driving end of the motor screw rod linear module is connected with a mounting plate, the mixing motor and the sample tube pushing motor are mounted on the mounting plate, and the clamping jaw is connected with the mixing motor and the driving end of the sample tube pushing motor.

3. The full-automatic chemiluminescence analyzer of claim 1, wherein the sample needle system comprises a sampling needle, a sample arm and a first transmission mechanism, wherein the sampling needle is arranged on the sample arm, the first transmission mechanism is arranged at the bottom of the sample arm, and the first transmission mechanism drives the sample arm to drive the sampling needle to move to the automatic sampling system, the mixing system or the reagent tray system.

4. The full-automatic chemiluminescence analyzer of claim 3, wherein the automatic sample feeding system further comprises a sample tube feeding position for feeding, a sample tube detection position for detecting a sample tube, a sample tube discharging position for discharging, a sample frame for loading the sample tube and a plurality of driving motors for driving the sample frame to move, the driving motors drive the sample frame to sequentially pass through the sample tube detection position, the emergency sample tube feeding device is arranged on one side of the sample tube detection position, and the sample tube detection position is positioned on the movement track of the sampling needle.

5. The full-automatic chemiluminescence analyzer of claim 3, wherein the emergency sample tube loading device comprises an emergency sample tube rack for storing emergency sample tubes and an emergency driver for driving the emergency sample tube rack to move, wherein an emergency position is arranged on the automatic sample injection system on the motion track of the sampling needle, and the emergency sample tube rack enters or leaves the emergency position through the emergency driver.

6. The full-automatic chemiluminescence analyzer of claim 3, wherein the incubation and cleaning system includes a needle cleaning basin for cleaning the sampling needle, the needle cleaning basin being disposed on a periphery of the incubation and cleaning system proximate the sample needle system, the needle cleaning basin being located on a motion profile of the sampling needle.

7. The full-automatic chemiluminescence analyzer of claim 1, wherein the incubation and cleaning system further comprises an incubation tray for incubating samples, a cleaning tray for cleaning the reaction cups, an incubation tray driver for driving the incubation tray to rotate, and a cleaning tray driver for driving the cleaning tray to rotate, wherein the cleaning tray is arranged above the incubation tray, a cup placing position for placing the reaction cups after incubation and a cup placing position for placing the reaction cups to be incubated are formed on the cleaning tray, and a liquid inlet assembly for performing cleaning operation is arranged above the cleaning tray.

8. The full-automatic chemiluminescence analyzer of claim 1, wherein the automatic cup feeding system comprises a storage bin for storing the reaction cups and a cup rolling chain for conveying the reaction cups, wherein the storage bin is arranged on one side of the cup rolling chain, a cup feeding opening is formed in the bottom of the storage bin and is communicated with the cup rolling chain, and the cup rolling chain drives the reaction cups to move to the periphery of the incubation and cleaning system.

9. The full-automatic chemiluminescence analyzer of claim 1, wherein the cup transporting system comprises a rotating arm, a second transmission mechanism for driving the rotating arm to rotate, and a clamping piece for carrying the reaction cup, and the rotating arm rotates to drive the clamping piece to clamp the reaction cup to reciprocate between the incubation and cleaning system and the mixing system.

10. The full-automatic chemiluminescence analyzer of claim 1, wherein the reagent tray system comprises a reagent kit for loading reagent, a reagent tray for driving the reagent kit to rotate, a reagent pan for mounting the reagent tray, a rotating motor for driving the reagent tray to rotate and a refrigerating air duct for reducing reagent temperature, and the reagent tray is connected with a driving end of the rotating motor.