CN112114159A - Continuous Delivery Device for Cuvette Incubation Photometry - Google Patents

Continuous Delivery Device for Cuvette Incubation Photometry Download PDF

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Publication number
CN112114159A
CN112114159A CN202011148281.7A CN202011148281A CN112114159A CN 112114159 A CN112114159 A CN 112114159A CN 202011148281 A CN202011148281 A CN 202011148281A CN 112114159 A CN112114159 A CN 112114159A
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reaction cup
cuvette
incubation
photometry
driving disc
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CN202011148281.7A
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Chinese (zh)
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刘聪
赵鹏
张汉杰
张刘涛
戎卫
王超
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Autobio Experimental Instrument Zhengzhou Co Ltd
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Autobio Experimental Instrument Zhengzhou Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0412Block or rack elements with a single row of samples

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a continuous conveying device for incubation and photometry of a reaction cup. Wherein, a reaction cup conveying track is arranged on the substrate; the driving disc is arranged above the reaction cup conveying rail, a plurality of through grooves which are crossed with the reaction cup conveying rail are formed in the driving disc, and the through grooves are sequentially arranged along the reaction cup conveying direction; the transmission mechanism is used for enabling the driving disc to move along the conveying direction of the reaction cups. The continuous conveying device for the incubation photometry of the reaction cups, provided by the invention, has the advantages of ingenious structure, small occupied space, low investment cost, safety, reliability and low failure rate, realizes the automatic transfer of the reaction cups from the previous station to the next station through the matching of the rails and the driving pieces, is accurate in positioning, is rapid and efficient, and can greatly improve the incubation photometry efficiency of the reaction cups.

Description

用于反应杯温育测光的连续输送装置Continuous Delivery Device for Cuvette Incubation Photometry

技术领域technical field

本发明涉及体外诊断仪器用输送设备技术领域,尤其是涉及一种用于反应杯温育测光的连续输送装置。The invention relates to the technical field of conveying equipment for in vitro diagnostic instruments, in particular to a continuous conveying device used for incubating photometry in reaction cups.

背景技术Background technique

全自动化学发光免疫分析系统、生化分析仪、实验室流水线、核酸等体外诊断设备大多会涉及反应杯输送机构。其中,对人体血清成分含量进行测光检测时,需要对盛装有血清试样的反应杯进行恒温培养。现有温育盘体积有限,只能对少量反应杯进行培养,且反应杯在进入温育盘之前进行磁洗、底物加注、混匀等预处理操作和温育完成之后进行测光操作时均需借助自动抓手将反应杯转移到目标位。由于涉及的操作工位较多,需要设置较多的抓手,导致整台设备体积大、投资高,同时,反应杯轮转频次较高,采用抓手抓取时反应杯运转速度较慢,导致测光检测整体效率较低。Most of the in vitro diagnostic equipment such as automatic chemiluminescence immunoassay system, biochemical analyzer, laboratory assembly line, nucleic acid, etc. will involve the cuvette conveying mechanism. Wherein, when performing photometric detection on the content of serum components in the human body, it is necessary to perform constant temperature incubation on the reaction cup containing the serum sample. The volume of the existing incubation plate is limited, and only a small number of reaction cups can be cultured, and the pretreatment operations such as magnetic washing, substrate injection, and mixing before the reaction cups enter the incubation plate, and photometric operations after the incubation are completed. The automatic gripper transfers the cuvette to the target position. Due to the number of operating stations involved, more grippers need to be set up, resulting in a large volume of the entire equipment and high investment. At the same time, the rotation frequency of the cuvette is high, and the cuvette running speed is slow when the gripper is used, resulting in The overall efficiency of photometric detection is low.

发明内容SUMMARY OF THE INVENTION

为了解决上述问题,本发明提供一种用于反应杯温育测光的连续输送装置,具体可采取如下技术方案:In order to solve the above-mentioned problems, the present invention provides a continuous conveying device for incubating photometry in reaction cups. Specifically, the following technical solutions can be adopted:

本发明所述的用于反应杯温育测光的连续输送装置,包括The continuous delivery device for incubating photometry in reaction cups according to the present invention comprises:

基板,其上设置有反应杯输送轨道;a base plate, on which a cuvette conveying track is arranged;

驱动盘,设置在所述反应杯输送轨道上方,所述驱动盘上开设有多个与反应杯输送轨道交叉设置的通槽,且所述通槽沿反应杯输送方向依次排列;A drive plate is arranged above the cuvette conveying track, and a plurality of through grooves intersecting with the cuvette conveying track are opened on the drive plate, and the through grooves are arranged in sequence along the cuvette conveying direction;

传动机构,用于使驱动盘沿反应杯输送方向移动。The transmission mechanism is used to move the drive plate along the conveying direction of the cuvette.

所述反应杯输送轨道为螺旋形、圆形或C形。The cuvette conveying track is spiral, circular or C-shaped.

所述反应杯输送轨道为单条连续形轨道。The cuvette conveying track is a single continuous track.

所述反应杯输送轨道的宽度与单个反应杯相适配。The width of the cuvette conveying track is adapted to a single cuvette.

所述反应杯输送轨道以所述转轴为中心设置。The cuvette conveying track is set with the rotating shaft as the center.

所述驱动盘为圆形结构,所述通槽沿驱动盘的径向设置。The drive disk is of a circular structure, and the through grooves are arranged along the radial direction of the drive disk.

所述通槽的宽度与单个反应杯相适配。The width of the through slot is adapted to a single cuvette.

所述传动机构包括The transmission mechanism includes

转轴,垂直于基板,具有第一端和第二端,所述第一端与基板相连,所述第二端与驱动盘的中心相连;A rotating shaft, perpendicular to the base plate, has a first end and a second end, the first end is connected with the base plate, and the second end is connected with the center of the drive disk;

驱动轮,设置在驱动盘一侧;The driving wheel is arranged on one side of the driving disc;

外齿圈,设置在驱动盘周缘,并与所述驱动轮啮合相连。The outer ring gear is arranged on the peripheral edge of the driving disc and is meshed and connected with the driving wheel.

所述转轴的第一端与基板固定相连,第二端通过滚珠轴承与驱动盘转动相连。The first end of the rotating shaft is fixedly connected to the base plate, and the second end is rotatably connected to the drive plate through a ball bearing.

所述驱动轮由设置在基板上的步进电机驱动。The driving wheel is driven by a stepping motor arranged on the base plate.

本发明提供的用于反应杯温育测光的连续输送装置,结构巧妙,占用空间小,投资成本低,安全可靠,故障率低,其通过轨道和驱动件的配合,实现了反应杯从上一工位到下一工位的自动转移,定位准确,快速高效,能够大幅提高反应杯的温育测光效率。The continuous conveying device for the incubation photometry of the reaction cup provided by the invention has the advantages of ingenious structure, small space occupation, low investment cost, safety and reliability, and low failure rate. The automatic transfer from one station to the next station, accurate positioning, fast and efficient, can greatly improve the incubation photometric efficiency of the reaction cup.

附图说明Description of drawings

图1是本发明的结构示意图。Figure 1 is a schematic structural diagram of the present invention.

图2是图1中驱动盘以下部分的结构示意图。FIG. 2 is a schematic structural diagram of the lower part of the drive disk in FIG. 1 .

具体实施方式Detailed ways

下面结合附图对本发明的实施例作详细说明,本实施例在以本发明技术方案为前提下进行实施,给出了详细的实施方式和具体的操作过程,但本发明的保护范围不限于下述实施例。The embodiments of the present invention will be described in detail below with reference to the accompanying drawings. This embodiment is implemented on the premise of the technical solution of the present invention, and provides detailed implementation modes and specific operation processes, but the protection scope of the present invention is not limited to the following described embodiment.

如图1、2所示,本发明所述的用于反应杯温育测光的连续输送装置,包括基板1,其上安装有反应杯输送轨道2;反应杯输送轨道上方设置有驱动盘3,驱动盘3上开设有多个与反应杯输送轨道交叉设置的通槽4,且通槽4沿反应杯输送方向依次排列;为了实现反应杯的输送,本发明还包括用于使驱动盘3沿反应杯输送方向移动的传动机构。As shown in Figures 1 and 2, the continuous conveying device for incubating photometry of reaction cups according to the present invention includes a substrate 1 on which a cuvette conveying track 2 is installed; a drive plate 3 is provided above the cuvette conveying track , the drive plate 3 is provided with a plurality of through grooves 4 that intersect the cuvette conveying track, and the through grooves 4 are arranged in sequence along the cuvette conveying direction; in order to realize the cuvette transportation, the present invention also includes a drive plate 3 for making the cuvette 3 A transmission mechanism that moves along the conveying direction of the cuvette.

具体地,反应杯输送轨道2固定安装在基板1上,其可以为螺旋形、圆形或C形轨道,本实施例中选用行程长、占据空间小的螺旋形轨道。一般情况下,反应杯输送轨道2为宽度与单个反应杯相适配的单轨道,其能够达到对单个反应杯连续输送的目的。在实际应用中,反应杯输送轨道2周边依次设置有为了满足检测要求配备的各种设备。Specifically, the cuvette conveying track 2 is fixedly installed on the substrate 1 , which can be a spiral, circular or C-shaped track. In this embodiment, a spiral track with a long stroke and a small footprint is selected. Generally, the cuvette conveying track 2 is a single track whose width is adapted to a single cuvette, which can achieve the purpose of continuously conveying a single cuvette. In practical applications, various equipments are arranged around the cuvette conveying track 2 in order to meet the detection requirements.

本实施例中驱动盘3为圆形结构,覆盖整个螺旋形轨道,并通过位于螺旋形反应杯输送轨道2中心处的转轴5与基板1相连。其上的通槽4分别沿驱动盘3的径向均匀设置,每个通槽4的宽度均与单个反应杯相适配。盛装试样的反应杯通过通槽4放置在反应杯输送轨道2内,当驱动盘3移动时,反应杯沿反应杯输送轨道2向前移动。由于驱动盘3上开设有多条通槽4,因此,与反应杯输送轨道2构成交叉点的通槽4有多个,可以同时放置多个反应杯,依次对其中的试样进行检测。In this embodiment, the drive plate 3 has a circular structure, covers the entire spiral track, and is connected to the substrate 1 through a rotating shaft 5 located at the center of the spiral cuvette conveying track 2 . The through grooves 4 thereon are uniformly arranged along the radial direction of the drive disk 3 respectively, and the width of each through groove 4 is adapted to a single reaction cup. The cuvette containing the sample is placed in the cuvette conveying track 2 through the through groove 4 . When the drive plate 3 moves, the cuvette moves forward along the cuvette conveying track 2 . Since the drive plate 3 is provided with a plurality of through grooves 4, there are multiple through grooves 4 forming intersections with the cuvette conveying track 2, and multiple cuvettes can be placed at the same time, and the samples in them can be tested in sequence.

在本实施例中,驱动盘3需要绕中心转动,与其相连的传动机构包括垂直于基板1设置的转轴5,该转轴5具有第一端和第二端,第一端与基板1固定相连,第二端通过滚珠轴承与驱动盘的中心转动相连;驱动盘3周缘套接有外齿圈6,或者将驱动盘3直接加工成齿轮状,在驱动盘3外侧安装有步进电机7驱动的驱动轮8,上述驱动轮8和外齿圈6啮合相连。当步进电机7启动时,驱动轮8带动外齿圈6和驱动盘3发生旋转运动。In this embodiment, the drive plate 3 needs to rotate around the center, and the transmission mechanism connected to it includes a rotating shaft 5 arranged perpendicular to the base plate 1 , the rotating shaft 5 has a first end and a second end, and the first end is fixedly connected to the base plate 1 , The second end is rotatably connected to the center of the drive plate through a ball bearing; the outer ring gear 6 is sleeved on the periphery of the drive plate 3, or the drive plate 3 is directly processed into a gear shape, and a stepping motor 7 is installed on the outside of the drive plate 3. The driving wheel 8, the above-mentioned driving wheel 8 and the outer ring gear 6 are meshed and connected. When the stepping motor 7 is started, the driving wheel 8 drives the outer ring gear 6 and the driving disc 3 to rotate.

工作时,将反应杯放入反应杯输送轨道2的起始处,步进电机7启动后,驱动盘3转动,在此过程中,反应杯输送轨道2对反应杯施加盘直径方向的约束,驱动盘3的通槽4对反应杯施加盘切线方向的约束。在驱动盘3和反应杯输送轨道2的共同约束下,反应杯会沿着反应杯输送轨道2从螺旋内圈以顺时针方向向外圈移动。由于基板1底部安装有加热盘,因此,在经过一段时间温育后,反应杯到达轨道周边的测光仪处进行测光分析,然后反应杯继续跟随驱动盘3继续转动,到达轨道末端的丢弃位,完成整个温育测光周期。When working, put the cuvette at the beginning of the cuvette conveying track 2. After the stepper motor 7 is started, the drive plate 3 rotates. During this process, the cuvette conveying track 2 imposes constraints on the cuvette in the diameter direction of the plate. The through groove 4 of the drive disk 3 imposes constraints on the cuvette in the tangential direction of the disk. Under the joint constraint of the drive disk 3 and the cuvette conveying track 2 , the cuvette will move along the cuvette conveying track 2 from the spiral inner circle to the outer circle in a clockwise direction. Since a heating plate is installed at the bottom of the substrate 1, after a period of incubation, the cuvette reaches the photometer around the track for photometric analysis, and then the cuvette continues to follow the drive plate 3 to continue to rotate until it reaches the end of the track and discarded bit to complete the entire incubation photometric cycle.

需要说明的是,在本发明的描述中,诸如“前”、“后”、“左”、“右”、“垂直”、“水平”、“内”、“外”等指示的方位或位置关系的术语是基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。It should be noted that, in the description of the present invention, the orientations or positions indicated such as "front", "rear", "left", "right", "vertical", "horizontal", "inner", "outer", etc. The terminology of the relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation , so it should not be construed as a limitation of the present invention.

Claims (10)

1. A continuous transport device for photometric incubation in cuvettes, comprising: comprises that
The substrate is provided with a reaction cup conveying track;
the driving disc is arranged above the reaction cup conveying rail, a plurality of through grooves which are crossed with the reaction cup conveying rail are formed in the driving disc, and the through grooves are sequentially arranged along the reaction cup conveying direction;
and the transmission mechanism is used for enabling the driving disc to move along the conveying direction of the reaction cups.
2. The continuous feeding device for cuvette incubation photometry according to claim 1, wherein: the reaction cup conveying track is spiral, circular or C-shaped.
3. The continuous feeding device for cuvette incubation photometry according to claim 2, wherein: the reaction cup conveying track is a single continuous track.
4. The continuous feeding device for cuvette incubation photometry according to claim 2, wherein: the width of the reaction cup conveying track is matched with that of a single reaction cup.
5. The continuous feeding device for cuvette incubation photometry according to claim 2, wherein: the reaction cup conveying track is arranged by taking the rotating shaft as the center.
6. The continuous feeding device for cuvette incubation photometry according to claim 1, wherein: the driving disc is of a circular structure, and the through grooves are arranged along the radial direction of the driving disc.
7. The continuous feed apparatus for cuvette incubation photometry according to claim 6, wherein: the width of the through groove is matched with that of a single reaction cup.
8. The continuous feed apparatus for cuvette incubation photometry according to claim 6, wherein: the transmission mechanism comprises
The rotating shaft is vertical to the substrate and is provided with a first end and a second end, the first end is connected with the substrate, and the second end is connected with the center of the driving disc;
the driving wheel is arranged on one side of the driving disc;
and the outer gear ring is arranged at the periphery of the driving disc and is meshed and connected with the driving wheel.
9. The continuous feed apparatus for cuvette incubation photometry according to claim 8, wherein: the first end of the rotating shaft is fixedly connected with the substrate, and the second end of the rotating shaft is rotatably connected with the driving disc through a ball bearing.
10. The continuous feed apparatus for cuvette incubation photometry of claim 9, wherein: the driving wheel is driven by a stepping motor arranged on the substrate.
CN202011148281.7A 2020-10-23 2020-10-23 Continuous Delivery Device for Cuvette Incubation Photometry Pending CN112114159A (en)

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CN202011148281.7A CN112114159A (en) 2020-10-23 2020-10-23 Continuous Delivery Device for Cuvette Incubation Photometry

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CN202011148281.7A CN112114159A (en) 2020-10-23 2020-10-23 Continuous Delivery Device for Cuvette Incubation Photometry

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843376A (en) * 1995-12-13 1998-12-01 Tosoh Corporation Reaction apparatus for automatic analysis
CN104714042A (en) * 2013-12-16 2015-06-17 深圳市亚辉龙生物科技有限公司 Full-automatic chemiluminescence immune analyzer and use method thereof
CN105190317A (en) * 2013-03-15 2015-12-23 雅培制药有限公司 Diagnostic analysis machine with preprocessing carousel and related method
CN209542458U (en) * 2019-02-26 2019-10-25 安图实验仪器(郑州)有限公司 Integral type for chemical illumination immunity analysis instrument incubates light measurer
US20200080998A1 (en) * 2018-09-11 2020-03-12 Shenzhen New Industries Biomedical Engineering Co., Ltd. Adsorption Mechanism, Cleaning Device, Chemiluminescence Detector and Cleaning Method
CN213813643U (en) * 2020-10-23 2021-07-27 安图实验仪器(郑州)有限公司 Continuous conveying device for incubation and photometry of reaction cups

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843376A (en) * 1995-12-13 1998-12-01 Tosoh Corporation Reaction apparatus for automatic analysis
CN105190317A (en) * 2013-03-15 2015-12-23 雅培制药有限公司 Diagnostic analysis machine with preprocessing carousel and related method
CN104714042A (en) * 2013-12-16 2015-06-17 深圳市亚辉龙生物科技有限公司 Full-automatic chemiluminescence immune analyzer and use method thereof
US20200080998A1 (en) * 2018-09-11 2020-03-12 Shenzhen New Industries Biomedical Engineering Co., Ltd. Adsorption Mechanism, Cleaning Device, Chemiluminescence Detector and Cleaning Method
CN209542458U (en) * 2019-02-26 2019-10-25 安图实验仪器(郑州)有限公司 Integral type for chemical illumination immunity analysis instrument incubates light measurer
CN213813643U (en) * 2020-10-23 2021-07-27 安图实验仪器(郑州)有限公司 Continuous conveying device for incubation and photometry of reaction cups

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