CN219907583U - Device for extracting stem cells from placenta - Google Patents
Device for extracting stem cells from placenta Download PDFInfo
- Publication number
- CN219907583U CN219907583U CN202321338837.8U CN202321338837U CN219907583U CN 219907583 U CN219907583 U CN 219907583U CN 202321338837 U CN202321338837 U CN 202321338837U CN 219907583 U CN219907583 U CN 219907583U
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- China
- Prior art keywords
- crushing
- box
- crushing box
- placenta
- pushing
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- 210000002826 placenta Anatomy 0.000 title claims abstract description 20
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 14
- 238000003756 stirring Methods 0.000 claims abstract description 38
- 238000007599 discharging Methods 0.000 claims abstract description 21
- 238000001914 filtration Methods 0.000 claims abstract description 20
- 238000005520 cutting process Methods 0.000 claims abstract description 18
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 5
- 210000005059 placental tissue Anatomy 0.000 description 11
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 4
- 241000220317 Rosa Species 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000000452 restraining effect Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 210000004504 adult stem cell Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000002662 placental hematopoietic stem cell Anatomy 0.000 description 1
Landscapes
- Crushing And Pulverization Processes (AREA)
Abstract
The utility model discloses a device for extracting stem cells from placenta, which comprises a crushing device, a stirring device and a filtering device; the crushing device comprises a crushing box and a crushing cutter arranged in the crushing box; the crushing cutter comprises a plurality of crisscross cutting blades; the cutting blades are mutually staggered to form a plurality of cuts; the top of the crushing box is provided with a lifting assembly for driving the cutting blade to move up and down; a push assembly is arranged in the crushing box; the pushing assembly comprises a fixed plate positioned on the top wall of the crushing box, a plurality of fixed rods arranged on the fixed plate, and a pushing block positioned at the lower end of the fixed rods; the pushing blocks and the fixing rods are arranged in one-to-one correspondence with the notches, and the shapes and the sizes of the pushing blocks and the notches are matched; when the crushing cutter is positioned at the uppermost part, the fixing rod is positioned in the notch, and the ejection block is positioned below the crushing cutter; the bottom of the crushing box is provided with a discharging pipe, and the other end of the discharging pipe is communicated with the stirring device; the bottom discharge pipe of the stirring device is communicated with the filtering device.
Description
Technical Field
The utility model relates to the technical field of biology, in particular to a device for extracting stem cells from placenta.
Background
Hematopoietic stem cells are adult stem cells in the blood system, and have the ability to self-renew for a long period of time and the potential to differentiate into various mature blood cells. In human term placenta, a large number of hematopoietic stem cells exist, and these placental hematopoietic stem cells can be isolated before and after frozen storage. When hematopoietic stem cells are separated and extracted from placenta, the placenta is washed for multiple times, the washed placenta is sheared by medical scissors, the length and width of the placenta are generally 1cm, then the sheared placenta tissue is put into a container, enzymolysis liquid is added for reaction for a certain time, then the reacted materials are filtered, filter residues are separated from filtrate, and the filtrate is used for further processing to obtain the hematopoietic stem cells.
In order to solve this problem, there is a method of crushing using a crushing blade having a plurality of crushing teeth, which is capable of crushing, but the placenta tissue after crushing is extremely likely to adhere between adjacent crushing teeth, resulting in difficulty in cleaning in the later stage.
Disclosure of Invention
In order to solve the problems, the utility model adopts the following technical scheme:
an apparatus for extracting stem cells from placenta comprises a crushing apparatus, a stirring apparatus and a filtering apparatus; the crushing device comprises a crushing box and a crushing cutter arranged in the crushing box; the crushing cutter comprises a plurality of crisscross cutting blades; the cutting blades are mutually staggered to form a plurality of cuts; the top of the crushing box is provided with a lifting assembly for driving the cutting blade to move up and down; a push assembly is arranged in the crushing box; the pushing assembly comprises a fixed plate positioned on the top wall of the crushing box, a plurality of fixed rods arranged on the fixed plate, and a pushing block positioned at the lower end of the fixed rods; the pushing blocks and the fixing rods are arranged in one-to-one correspondence with the notches, and the shapes and the sizes of the pushing blocks and the notches are matched; when the crushing cutter is positioned at the uppermost part, the fixing rod is positioned in the notch, and the ejector block is positioned below the crushing cutter; the bottom of the crushing box is provided with a discharging pipe, and the other end of the discharging pipe is communicated with the stirring device; the bottom discharge pipe of the stirring device is communicated with the filtering device.
Further, the lifting assembly comprises at least one cylinder located outside the crushing box; the telescopic rod of the air cylinder extends into the crushing box and is connected with the edge of the crushing cutter.
Further, the discharging pipe is arranged at one side of the crushing box; a pushing component is arranged on one side, far away from the discharging pipe, of the crushing box; the pushing assembly comprises a pushing rod penetrating through the side wall of the crushing box and a pushing plate arranged at the end part of the pushing rod; the pushing plate is abutted with the bottom plate of the crushing box; and a limiting component used for limiting the position of the pushing plate is arranged outside the crushing box.
Further, the limiting assembly comprises a mounting plate arranged on the crushing box, a limiting rod penetrating through the mounting plate, a chuck arranged on the limiting rod and a spring sleeved on the limiting rod; the pushing rod is provided with a clamping groove, and the clamping groove is matched with the limiting rod; the chuck is arranged below the mounting plate; the spring is located between the chuck and the mounting plate.
Further, the crushing box is obliquely arranged, and the discharging pipe is positioned at the lower end of the crushing box.
Further, the stirring device comprises a stirring box and a stirring assembly positioned in the stirring box; the stirring box is provided with a feeding pipe.
Further, the filtering device comprises a filtering box and a filter screen arranged in the filtering box, and a bottom discharge pipe of the stirring device extends to the upper part of the filter screen; the bottom of the stirring device is provided with a filtrate outlet; the top of the filter box is provided with a filter box door.
Further, the cross-section of filter screen is the arc, be provided with in the filter screen rather than the helical blade of shape matching, helical blade is by being located the outside driving motor drive rotation of rose box, be provided with the filter residue outlet pipe on the lateral wall of rose box.
The utility model has the beneficial effects that: 1. the utility model is provided with a plurality of crisscross cutting blades in the crushing box, and the lifting component drives the cutting blades to move downwards to cut placenta; because the pushing component is arranged in the utility model, if placenta tissues are blocked in each incision, the lifting component drives the cutting blade to move upwards, and the pushing block pushes the placenta tissues in the incision out and falls to the bottom of the breaking box, so that the placenta tissues are not easy to block in the incision, and the difficulty of later cleaning is reduced. 2. The utility model is provided with the pushing component, and when the cutting is completed, the pushing rod is manually pushed, so that the pushing plate pushes the crushed placenta tissues to the discharging pipe, and the placenta tissues are conveniently discharged.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present utility model;
FIG. 2 is a schematic view of the crushing cutter of the present utility model;
reference numerals: 1. a crushing box; 2. a stirring tank; 3. a filter box; 4. a fixing plate; 5. a fixed rod; 6. crushing a cutter; 7. a cylinder; 8. pushing the jacking block; 9. a pushing plate; 10. a limit rod; 11. a mounting plate; 12. a spring; 13. a chuck; 14. a clamping groove; 15. a push rod; 16. a discharge pipe; 17. a stirring assembly; 18. a discharge pipe; 19. a filter screen; 20. helical blades.
Detailed Description
The technical solution of the present utility model will be further described with reference to fig. 1-2 and examples, so that those skilled in the art can more clearly understand the content of the technical solution.
Examples
There is provided in this embodiment an apparatus for extracting stem cells from placenta, comprising a crushing apparatus including a crushing tank 1, and a crushing cutter 6 provided in the crushing tank 1; the crushing cutter 6 comprises a plurality of crisscrossed cutting blades; the cutting blades are mutually staggered to form a plurality of cuts; the top of the crushing box 1 is provided with a lifting assembly for driving the cutting blade to move up and down; the lifting assembly comprises at least one cylinder 7 located outside the crushing tank 1; the telescopic rod of the air cylinder 7 extends into the crushing box 1 and is connected with the edge of the crushing cutter 6. The cylinder can be replaced by an electric push rod, namely, the function of driving the crushing cutter to move up and down is realized.
A push assembly is arranged in the crushing box 1; the pushing assembly comprises a fixed plate 4 positioned on the top wall of the crushing box 1, a plurality of fixed rods 5 arranged on the fixed plate 4, and a pushing block 8 positioned at the lower end of the fixed rods 5; the ejector blocks 8 and the fixing rods 5 are arranged in one-to-one correspondence with the notches, and the ejector blocks 8 are matched with the notches in shape and size; when the crushing cutter 6 is positioned at the uppermost part, the fixed rod 5 is positioned in the notch, and the ejector block 8 is positioned below the crushing cutter 6; the bottom of the crushing box 1 is provided with a discharge pipe 16, and the other end of the discharge pipe 16 is communicated with the stirring device; the bottom discharge pipe 18 of the stirring device is in communication with the filtering device. The crushing box 1 is obliquely arranged, and the discharging pipe 16 is positioned at the lower end of the crushing box 1.
The pushing assembly is arranged at the position, and after the lifting assembly drives the crushing cutter to move downwards to finish one-time cutting operation, the crushing cutter is driven to move upwards until the pushing block stretches into the notch, and placenta tissues blocked in the notch are ejected out, so that placenta tissues are prevented from remaining in the cutter. In addition, in the embodiment, the sealing door is additionally arranged on the side wall of the crushing box, and when the inside needs to be cleaned, the sealing door can be opened to manually clean the inside.
In this embodiment, no improvement is made on the stirring device and the filtering device, that is, any device with stirring function and filtering function in the prior art is adopted.
Examples
This embodiment differs from embodiment 1 in that: a pushing component is arranged on one side of the crushing box 1 far away from the discharging pipe 16; the pushing assembly comprises a pushing rod 15 penetrating through the side wall of the higher end of the crushing box 1 and a pushing plate arranged at the end part of the pushing rod 15; the pushing plate is abutted with the bottom plate of the crushing box 1; and a pull ring is arranged at one end of the pushing rod, which is positioned outside the crushing box. And a limiting component for limiting the position of the pushing plate is arranged outside the crushing box 1. The pushing assembly is arranged in the embodiment, after cutting is completed, the pushing rod is pushed outside, so that the pushing plate pushes placenta tissues on the bottom plate to move towards the direction of the discharging pipe, and the placenta tissues drop downwards from the discharging pipe and enter the stirring device below. The discharging pipe can be a pipeline with a rectangular section, and the width of the discharging pipe is consistent with the width of the crushing box, so that the discharging pipe is convenient to discharge.
In addition, the limiting assembly in the embodiment comprises a mounting plate 11 arranged on the crushing box 1, a limiting rod 10 penetrating through the mounting plate 11, a chuck 13 arranged on the limiting rod 10, and a spring 12 sleeved on the limiting rod 10; a clamping groove 14 is formed in the pushing rod 15, and the clamping groove 14 is matched with the limiting rod 10; the chuck 13 is arranged below the mounting plate 11; the spring 12 is located between the chuck 13 and the mounting plate 11. An anti-drop disc can be additionally arranged at the upper end of the limiting rod to prevent the limiting block from dropping out of the mounting plate. That is, when the pusher plate is not used, the pusher plate is restrained at the upper end of the crushing box by the restraining assembly, and the restraining bar is inserted into the catching groove. When the pushing plate is required to be used, the limiting rod is pulled upwards, so that the limiting rod is separated from the clamping groove, and the pushing plate can be moved.
Examples
This embodiment differs from embodiment 1 in that: in this embodiment, a specific structure of a stirring device and a filtering device is provided. The stirring device comprises a stirring box 2 and a stirring assembly 17 positioned in the stirring box 2; the stirring tank 2 is provided with a feeding pipe. The enzymolysis liquid enters the stirring box from the feeding pipe.
The filtering device comprises a filtering box 3 and a filter screen 19 arranged in the filtering box 3, and a bottom discharge pipe 18 of the stirring device extends to the upper part of the filter screen 19; the bottom of the stirring device is provided with a filtrate outlet; the top of the filter box 3 is provided with a filter box door. The filter residue in this embodiment is taken out from the upper filter box door.
Examples
In this embodiment, the structure of the filtering device is further improved, in this embodiment, the cross section of the filter screen 19 is arc-shaped, a spiral blade 20 matched with the filter screen 19 in shape is disposed in the filter screen 19, the spiral blade 20 is driven to rotate by a driving motor located outside the filter tank 3, and a filter residue outlet pipe is disposed on the side wall of the filter tank 3. That is, after the filtration is completed, the driving motor is started to drive the spiral blade to rotate, so that the filter residue is discharged out of the device.
Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment is provided with a separate embodiment, and that this description is provided for clarity only, and that the disclosure is not limited to the embodiments described in detail below, and that the embodiments described in the examples may be combined as appropriate to form other embodiments that will be apparent to those skilled in the art.
Claims (8)
1. The utility model provides a device of stem cell is drawed from placenta, includes breaker, agitating unit and filter equipment, its characterized in that: the crushing device comprises a crushing box (1) and a crushing cutter (6) arranged in the crushing box (1); the crushing cutter (6) comprises a plurality of crisscrossed cutting blades; the cutting blades are mutually staggered to form a plurality of cuts; the top of the crushing box (1) is provided with a lifting assembly for driving the cutting blade to move up and down; a push assembly is arranged in the crushing box (1); the ejection assembly comprises a fixed plate (4) positioned on the top wall of the crushing box (1), a plurality of fixed rods (5) arranged on the fixed plate (4), and an ejection block (8) positioned at the lower end of the fixed rods (5); the ejector blocks (8) and the fixing rods (5) are arranged in one-to-one correspondence with the notches, and the ejector blocks (8) are matched with the notches in shape and size; when the crushing cutter (6) is positioned at the uppermost part, the fixed rod (5) is positioned in the notch, and the ejector block (8) is positioned below the crushing cutter (6); the bottom of the crushing box (1) is provided with a discharging pipe (16), and the other end of the discharging pipe (16) is communicated with the stirring device; the bottom discharge pipe (18) of the stirring device is communicated with the filtering device.
2. The apparatus for extracting stem cells from placenta as defined in claim 1, wherein: the lifting assembly comprises at least one cylinder (7) located outside the crushing box (1); the telescopic rod of the air cylinder (7) extends into the crushing box (1) and is connected with the edge of the crushing cutter (6).
3. The apparatus for extracting stem cells from placenta as defined in claim 1, wherein: the discharging pipe (16) is arranged at one side of the crushing box (1); a pushing component is arranged on one side, far away from the discharging pipe (16), of the crushing box (1); the pushing assembly comprises a pushing rod (15) penetrating through the side wall of the crushing box (1) and a pushing plate arranged at the end part of the pushing rod (15); the pushing plate is abutted with the bottom plate of the crushing box (1); and a limiting component used for limiting the position of the pushing plate is arranged outside the crushing box (1).
4. The apparatus for extracting stem cells from placenta as defined in claim 3, wherein: the limiting assembly comprises a mounting plate (11) arranged on the outer wall of the crushing box (1), a limiting rod (10) penetrating through the mounting plate (11), a chuck (13) arranged on the limiting rod (10) and a spring (12) sleeved on the limiting rod (10); a clamping groove (14) is formed in the pushing rod (15), and the clamping groove (14) is matched with the limiting rod (10); the chuck (13) is arranged below the mounting plate (11); the spring (12) is located between the chuck (13) and the mounting plate (11).
5. The apparatus for extracting stem cells from placenta as defined in claim 1, wherein: the crushing box (1) is obliquely arranged, and the discharging pipe (16) is positioned at the lower end of the crushing box (1).
6. The apparatus for extracting stem cells from placenta as defined in claim 1, wherein: the stirring device comprises a stirring box (2) and a stirring assembly (17) positioned in the stirring box (2); the stirring box (2) is provided with a feeding pipe.
7. The apparatus for extracting stem cells from placenta as defined in claim 1, wherein: the filtering device comprises a filtering box (3) and a filter screen (19) arranged in the filtering box (3), and a bottom discharging pipe (18) of the stirring device extends to the upper part of the filter screen (19); the bottom of the stirring device is provided with a filtrate outlet; the top of the filter box (3) is provided with a filter box door.
8. The apparatus for extracting stem cells from placenta as defined in claim 7, wherein: the section of filter screen (19) is the arc, be provided with in filter screen (19) rather than shape matching helical blade (20), helical blade (20) are rotated by the driving motor drive that is located the filter tank (3) outside, be provided with the filter residue outlet pipe on the lateral wall of filter tank (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321338837.8U CN219907583U (en) | 2023-05-30 | 2023-05-30 | Device for extracting stem cells from placenta |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321338837.8U CN219907583U (en) | 2023-05-30 | 2023-05-30 | Device for extracting stem cells from placenta |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219907583U true CN219907583U (en) | 2023-10-27 |
Family
ID=88434116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321338837.8U Active CN219907583U (en) | 2023-05-30 | 2023-05-30 | Device for extracting stem cells from placenta |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219907583U (en) |
-
2023
- 2023-05-30 CN CN202321338837.8U patent/CN219907583U/en active Active
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