CN219168669U

CN219168669U - Separating tube

Info

Publication number: CN219168669U
Application number: CN202223609100.3U
Authority: CN
Inventors: 袁晔; 李慧伦; 曹军廷; 方想元; 袁建华
Original assignee: Guangzhou Jet Bio Filtration Co Ltd
Current assignee: Guangzhou Jet Bio Filtration Co Ltd
Priority date: 2022-12-30
Filing date: 2022-12-30
Publication date: 2023-06-13
Anticipated expiration: 2032-12-30

Abstract

The utility model relates to the technical field of cell centrifugation devices, and discloses a separation tube which comprises a tube body and an insert, wherein the insert is arranged in the tube body and comprises a baffle plate, a support body and a reinforcement body; the middle part of the baffle is provided with a central hole; the supporting body is of a cylindrical structure and is connected to the bottom surface of the partition board, and a plurality of second raised strips are arranged on the inner peripheral wall of the supporting body along the circumferential direction; the reinforcement body comprises reinforcement wings and a flow guiding part, the top of the flow guiding part is connected to the bottom surface of the partition plate, the flow guiding part is cylindrical and communicated with the central hole, the reinforcement wings are arranged on the periphery of the flow guiding part at intervals, one side of each reinforcement wing is connected with the flow guiding part, and the other side of each reinforcement wing is connected with the inner peripheral wall of the support body. The bottom of the partition board is provided with the supporting body and the reinforcing body, so that the strength of the partition board can be enhanced, and the cracking is avoided. And the second raised strips are arranged on the circumference of the support body, and the reinforcement body is connected to the inner circumferential wall of the support body, so that the structural strength of the support body can be enhanced, and the overall structural strength of the separation tube is further ensured.

Description

Separating tube

Technical Field

The utility model relates to the technical field of cell centrifugation devices, in particular to a separation tube.

Background

Centrifugal separation is one of the most commonly used cell separation means in the fields of biology and medicine, and is commonly used for the performance research, expansion culture, disease diagnosis and disease treatment of specific cells.

The existing separating tube is generally internally provided with an insert, a barrier is formed between the centrifugate and the blood sample, substances in the separating tube can be layered after the centrifugate treatment, and target cell groups can be separated by pouring the separating tube or sucking the substances by using a test tube. However, the existing separator tube inserts are relatively thin and lightweight and are subject to breakage during centrifugation.

Disclosure of Invention

The purpose of the utility model is that: the utility model provides a separating tube, solves the problem that current separating tube easily breaks.

In order to achieve the above object, the present utility model provides a separator tube comprising a tube body and an insert provided inside the tube body, the insert comprising a separator plate, a support body and a reinforcement body; the middle part of the partition board is provided with a central hole penetrating through the upper side surface and the lower side surface of the partition board;

the support body is of a cylindrical structure, the top of the support body is connected to the bottom of the partition plate, a plurality of second raised strips are arranged on the inner peripheral wall of the support body, and the second raised strips are arranged at intervals along the circumferential direction of the support body;

the reinforcing body is arranged in the supporting body, the reinforcing body comprises a flow guiding part and a plurality of reinforcing wings, the flow guiding part is cylindrical, the top of the flow guiding part is connected to the bottom surface of the partition plate and communicated with the center hole, the reinforcing wings are circumferentially arranged on the periphery of the flow guiding part at intervals, one side of each reinforcing wing is connected with the flow guiding part, and the other side of each reinforcing wing is connected with the inner peripheral wall of the supporting body.

Further, the bottom surface of baffle is equipped with a plurality of first sand grip, first sand grip is followed the radial extension of baffle, and a plurality of first sand grip regard as the centre at the centre and be circumference interval distribution, a plurality of first sand grip integrated into one piece in on the baffle.

Further, one side of the reinforcing wing is connected to the second raised strips, and the reinforcing wing and the second raised strips are arranged in one-to-one correspondence.

Further, the partition plate is arranged in a downward concave manner.

Further, the outer circumference of the insert is fixedly connected to the inner circumferential wall of the tube body by ultrasonic welding.

Further, a gap is provided between the support body and the inner peripheral wall of the tube body.

Further, a plurality of ventilation holes are formed in the circumference of the partition board, and the ventilation holes penetrate through the upper side face and the lower side face of the partition board.

Further, the support body is provided with a plurality of notches which are opened downwards along the circumferential direction at one side far away from the partition plate, and the notches penetrate through the inner circumferential wall and the outer circumferential wall of the support body.

Further, the length of the reinforcement is smaller than the length of the support.

Further, the pipe body further comprises a top cover, and the top cover is connected with the top of the pipe body in a sealing mode.

Compared with the prior art, the separating tube has the beneficial effects that: the bottom surface of baffle is equipped with supporter and reinforcement, can strengthen the intensity of baffle, avoids breaking in the centrifugation process. And be equipped with the second sand grip along circumference on the internal perisporium of supporter, the reinforcement body is connected in the internal perisporium of supporter, homoenergetic reinforcing support body's structural strength, further ensure the overall structural strength of separator tube.

Drawings

FIG. 1 is a perspective view of a separator tube according to an embodiment of the present utility model;

FIG. 2 is a cross-sectional view of a separator tube according to an embodiment of the present utility model;

FIG. 3 is a block diagram of a first view of an insert according to an embodiment of the present utility model;

FIG. 4 is a block diagram of a second view of an insert according to an embodiment of the present utility model;

FIG. 5 is a cross-sectional view of an insert according to an embodiment of the present utility model;

in the figure, 100, separating tubes; 1. a tube body; 2. an insert; 21. a partition plate; 211. a central bore; 212. ventilation holes; 22. a support body; 221. a notch; 23. a reinforcement; 231. reinforcing wings; 232. a flow guiding part; 24. a first protruding strip; 25. a second protruding strip; 26. a gap; 3. and a top cover.

Detailed Description

The following describes in further detail the embodiments of the present utility model with reference to the drawings and examples. The following examples are illustrative of the utility model and are not intended to limit the scope of the utility model.

In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "inside", "outside", "inner peripheral wall", "outer peripheral wall", "top", "bottom", etc. in the present utility model are based on the orientation or positional relationship shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model.

As shown in fig. 1 to 5, a separator tube 100 according to a preferred embodiment of the present utility model includes a tube body 1 and an insert 2, the insert 2 being provided inside the tube body 1, the insert 2 including a partition 21, a support 22, and a reinforcement 23. The middle part of baffle 21 is equipped with the centre bore 211 that runs through its upper and lower side, the bottom surface of baffle 21 is equipped with a plurality of first sand grip 24, first sand grip 24 is along the radial extension of baffle 21, and a plurality of first sand grip 24 take centre bore 211 is circumference interval distribution as the center.

The supporting body 22 is in a cylindrical structure, the top of the supporting body 22 is connected to the bottom of the partition plate 21, a plurality of second raised strips 25 are arranged on the inner peripheral wall of the supporting body 22, and the plurality of second raised strips 25 are arranged at intervals along the circumferential direction of the supporting body 22.

The reinforcement body 23 is disposed in the support body 22, and the reinforcement body 23 includes a guide portion 232 and a plurality of reinforcement wings 231, the guide portion 232 is cylindrical, and the top of the guide portion 232 is connected to the bottom surface of the partition 21 and is communicated with the central hole 211, the reinforcement wings 231 are circumferentially spaced from each other and disposed on the periphery of the guide portion 232, one side of each reinforcement wing 231 is connected with the guide portion 232, the other side of each reinforcement wing 231 is connected with the inner peripheral wall of the support body 22, and the top of each reinforcement wing 231 is connected to the bottom surface of the partition 21 so as to strengthen the structural strength of the partition 21 and the support body 22.

Based on this, the separation liquid is carried on the bottom of the separation tube 100 through the central hole 211 and the flow guide part 232, the blood sample is stacked on the upper side of the partition plate 21, then the separation tube 100 is placed on the centrifuge for centrifugal separation, under the agglutination of the separation liquid, the substances with larger densities such as red blood cells are deposited on the bottom of the separation tube 100, the substances with smaller densities such as plasma are separated on the upper layer, and the substances can be separated by tilting the separation tube 100 or sucking by a suction tube. The bottom of the partition plate 21 in the embodiment of the utility model is provided with a plurality of first raised strips 24 along the circumferential direction, and the bottom surface of the partition plate 21 is also provided with a supporting body 22 and a reinforcing body 23, so that the structural strength of the partition plate 21 can be enhanced, and the partition plate 21 is prevented from being broken in the high-speed rotation process. And the second raised strips 25 are arranged on the inner peripheral wall of the support body 22 along the circumferential direction, and the plurality of reinforcing wings 231 are distributed at intervals and connected to the inner peripheral wall of the support body 22, so that the structural strength of the support body 22 can be enhanced, and the overall structural strength of the separation tube 100 is further ensured.

Further, the first protruding strips 24 are integrally formed on the partition 21, so as to ensure the stability of the overall structure, and the manufacturing is simple and convenient.

Further, one side of the reinforcing wing 231 is connected to the second protruding strip 25, and the reinforcing wing 231 and the second protruding strip 25 are disposed in one-to-one correspondence, so as to ensure the structural strength of the supporting body 22 and avoid damage due to the light and thin supporting body 22. Preferably, the number of the reinforcing wings 231 is four, and the reinforcing wings are uniformly distributed around the outer circumferential wall of the guide part 232, so that the separation tube 100 is mass-balanced, and breakage during centrifugation is avoided.

Further, before centrifugal separation, the separating liquid needs to pass through the central hole 211 and the guide portion 232 to be carried at the bottom of the separating tube 100, and the partition 21 in the embodiment of the utility model is arranged in a downward recess, so that the separating liquid is conveniently loaded under the action of gravity, and the difficulty in loading the separating liquid is reduced.

Further, the inner diameter of the guiding part 232 is larger than the diameter of the central hole 211, so as to ensure that substances in the blood sample can be smoothly centrifuged and layered in the centrifugal separation process, and avoid blockage.

Further, the outer periphery of the insert 2 is fixedly connected to the inner peripheral wall of the pipe body 1 by ultrasonic welding, so that the overall structure is simple and the connection is stable.

Further, a gap 26 is formed between the support 22 and the inner peripheral wall of the pipe body 1, that is, the fixation between the insert 2 and the pipe body 1 is achieved by welding between the outer periphery of the partition 21 and the pipe body 1, so that the insert 2 is conveniently placed inside the pipe body 1 and the welding difficulty is reduced.

Further, in order to allow air to escape, the air pressure on the upper and lower sides of the partition plate 21 is balanced, a plurality of ventilation holes 212 are formed in the circumferential direction of the partition plate 21, and the ventilation holes 212 penetrate through the upper and lower side surfaces of the partition plate 21. Specifically, the ventilation holes 212 are preferably formed as U-shaped holes extending from the center of the outer circumference of the partition plate 21 by a distance, and the ventilation holes 212 are disposed across the inner and outer sides of the support body 22, i.e., the ventilation holes 212 can communicate with the gap 26 and the upper side of the partition plate 21, and the ventilation holes 212 can communicate with the inner side of the support body 22 and the upper side of the partition plate 21, thereby ensuring the normal flow of air inside the separation tube 100 during the centrifugation.

Further, the support 22 is provided with a plurality of notches 221 which are opened downwards along the circumferential direction at the side far away from the partition 21, and the notches 221 penetrate through the inner circumferential wall and the outer circumferential wall of the support 22, so that the air flow between the inner circumference and the outer circumference of the support 22 is ensured, and the air pressure imbalance at the inner side and the outer side of the support 22 is avoided to damage the structure.

Further, the length of the reinforcement 23 is smaller than the length of the support 22, avoiding waste of material and reducing the influence on material stratification during centrifugation. Further, the separation tube 100 further comprises a top cover 3, the top cover 3 is connected with the top of the tube body 1 in a sealing manner, after the blood sample and the separation liquid are loaded into the separation tube 100, the separation tube 100 is sealed by using the top cover 3, and centrifugal operation is performed, so that internal substances are prevented from being thrown out.

The working process of the utility model is as follows: the separation liquid enters the bottom of the separation tube 100 through the central hole 211 and the flow guiding part 232, the blood sample is diluted and stacked on the upper side of the partition plate 21, then the separation tube 100 is sealed by the top cover 3, and the separation tube 100 is placed on a centrifuge for centrifugal separation.

In summary, the embodiment of the present utility model provides a separating tube 100, where the bottom of the partition 21 is provided with a first protruding strip 24, and the bottom of the partition 21 is further provided with a supporting body 22 and a reinforcing body 23, so that the structural strength of the partition 21 can be enhanced, and cracking in the high-speed rotation process is avoided. The second protruding strips 25 on the periphery Xiang Sheyou of the support body 22 are distributed at intervals and connected with the inner peripheral wall of the support body 22, so that the structural strength of the support body 22 can be enhanced, and the overall structural strength of the separation tube 100 can be further ensured. And the reinforcing wings 231 are arranged in one-to-one correspondence with the second raised strips 25 and are uniformly distributed on the inner peripheral wall of the support body 22, so as to ensure the strength of the support body 22 and the quality balance of the separation tube 100, and avoid cracking in the centrifugation process.

And the partition plate 21 is arranged in a downward concave manner, so that the separating liquid can be conveniently loaded under the action of gravity.

The reinforcement body 23 has a guiding portion 232, the guiding portion 232 plays a guiding role in separating substances, the inner diameter of the guiding portion 232 is larger than the diameter of the central hole 211, so that the substances in the separating tube 100 can be ensured to be smoothly centrifuged and layered, and blocking is avoided.

The foregoing is merely a preferred embodiment of the present utility model, and it should be noted that modifications and substitutions can be made by those skilled in the art without departing from the technical principles of the present utility model, and these modifications and substitutions should also be considered as being within the scope of the present utility model.

Claims

1. A separating tube comprising a tube body and an insert, wherein the insert is arranged in the tube body; the middle part of the partition board is provided with a central hole penetrating through the upper side surface and the lower side surface of the partition board;

2. The separator tube of claim 1, wherein the bottom surface of the separator plate is provided with a plurality of first protruding strips, the first protruding strips extend in the radial direction of the separator plate, the plurality of first protruding strips are circumferentially spaced apart around the central hole, and the plurality of first protruding strips are integrally formed on the separator plate.

3. The separator tube of claim 1, wherein one side of the reinforcing fin is connected to the second raised strip, and the reinforcing fin is disposed in one-to-one correspondence with the second raised strip.

4. The separator tube of claim 1, wherein the separator plate is downwardly concave.

5. The separator tube of claim 1, wherein the outer periphery of the insert is fixedly attached to the inner peripheral wall of the tube body by ultrasonic welding.

6. The separator tube of claim 1, wherein a gap is provided between the support body and an inner peripheral wall of the tube body.

7. The separator tube of claim 6, wherein a plurality of ventilation holes are formed in the circumference of the separator plate, and the ventilation holes penetrate through the upper and lower sides of the separator plate.

8. A separator tube as claimed in claim 1, wherein the support body is provided with a plurality of downwardly opening slots in the circumferential direction at a side remote from the separator plate, the slots extending through the inner and outer peripheral walls of the support body.

9. The separator tube of claim 1, wherein the length of the reinforcement is less than the length of the support.

10. The separator tube of claim 1, further comprising a top cap sealingly connected to the top of the tube body.