CN219111666U - Centrifugal device - Google Patents

Abstract

The application provides a centrifugal device relates to centrifuging tube technical field. The centrifugal device includes: the centrifugal structure is provided with a containing cavity, the containing cavity is configured to contain whole blood, and a first pipetting hole, a second pipetting hole and a third pipetting hole are arranged at intervals along the periphery of the centrifugal structure; the pipette structure comprises a first pipette, a second pipette and a third pipette, wherein the first pipette is configured to be connected with the first pipetting hole for injecting whole blood into the accommodating cavity and drawing out the erythrocyte layer after the whole blood is centrifuged for the first time, the second pipette is configured to be connected with the second pipetting hole for drawing out platelet-rich plasma generated after the whole blood is centrifuged for the second time, and the third pipette is configured to be connected with the third pipetting hole for drawing out platelet-rich plasma generated after the whole blood is centrifuged for the second time. Can realize special use of special tube, effectively avoid residual red blood cells from mixing into platelet-rich plasma, and improve the centrifugal treatment effect on whole blood.

Description

Centrifugal device

Technical Field

The application relates to the technical field of centrifuge tubes, in particular to a centrifugal device.

Background

Platelet-Rich Plasma (PRP) is a Platelet concentrate extracted from autologous blood by centrifugation and contains high concentrations of platelets, leukocytes and fibrin. Platelets can secrete a variety of growth factors upon activation: leukocytes can prevent infection, and fibrin can locally build up the three-dimensional structure required for tissue repair. The concentrated PRP component not only can provide concentrated nutrition for tissue repair, but also can build a better repair environment for tissue repair. Numerous basic studies and clinical trials have demonstrated that PRP can significantly promote the repair of bone and soft tissues. Since PRP is autologous, safe and effective, and has been increasingly used clinically in recent years, PRP has been applied to orthopaedics, oral and maxillofacial surgery, plastic surgery, cosmetology, sports medicine, neurosurgery, ophthalmology, otorhinolaryngology, obstetrics and gynecology, etc.

However, in the related technology, the existing centrifuge tube has the common pipeline for red blood cells and PRP extraction, so that the concentration of red blood cells in PRP is increased, and the centrifugation of whole blood is not facilitated.

Disclosure of Invention

The purpose of the application is to provide a centrifugal device and a centrifugal method, which can realize special use of a special tube and improve the centrifugal treatment effect on whole blood.

In order to achieve the above purpose, the present application adopts the following technical scheme:

in a first aspect, the present application provides a centrifuge device comprising: a centrifugal structure, which is provided with a containing cavity, wherein the containing cavity is used for containing whole blood, and a first pipetting hole, a second pipetting hole and a third pipetting hole are arranged at intervals along the periphery of the centrifugal structure; a pipette structure comprising a first pipette configured to be connected with the first pipetting hole for injecting the whole blood into the receiving cavity and withdrawing a red blood cell layer after the first centrifugation of the whole blood, a second pipette configured to be connected with the second pipetting hole for withdrawing platelet rich plasma generated after the second centrifugation of the whole blood, and a third pipette configured to be passed through the third pipetting hole for withdrawing platelet rich plasma generated after the second centrifugation.

In the process of the realization, the periphery of the centrifugal structure is provided with a first pipetting hole, a second pipetting hole and a third pipetting hole, the first pipette is connected with the first pipetting hole, the second pipette is connected with the second pipetting hole, the third pipette is matched with the third pipetting hole for use, after centrifugation, the erythrocyte layer can be discharged through the first pipette, the third pipette discharges the platelet-rich plasma, finally, the platelet-rich plasma is extracted through the second pipette, special use of a special tube can be realized, residual erythrocytes are effectively prevented from being mixed into the platelet-rich plasma, and the centrifugal treatment effect on whole blood is improved.

In some embodiments, the centrifugal structure comprises a centrifugal body and a liquid collecting body, the centrifugal body is connected with the liquid collecting body, the first suction pipe and/or the second suction pipe are/is respectively contacted with the liquid collecting body, and the liquid collecting body is arranged in a contracted shape, so that the pipe diameter of the liquid collecting body, which is close to one side of the centrifugal body, is larger than the pipe diameter of the liquid collecting body, which is far away from one side of the centrifugal body.

In the process of the realization, the liquid collecting body is connected with the centrifugal body, and the whole blood is injected into the accommodating cavity through the first suction pipe and the first liquid transferring hole and flows to the liquid collecting body, and the liquid collecting body is arranged to be contracted, so that the centrifugal structure is beneficial to extracting the centrifuged whole blood after centrifuging the whole blood.

In some embodiments, the liquid collection body includes a straight line segment, an arc segment, and a bottom surface, the arc segment is located between the straight line segment and the bottom surface, and a side of the straight line segment remote from the arc segment is configured to be connected with the centrifugal body.

In the process of the realization, the circular arc section is respectively connected with the straight line section and the bottom surface, when whole blood is injected into the accommodating cavity and centrifuged, the liquid collecting body is provided with the straight line section and the circular arc section, so that the liquid collecting body forms a contracted shape, and the whole blood after centrifugation is extracted.

In some embodiments, a side of the first pipette remote from the first pipetting hole is configured to contact the bottom surface such that the first pipette and the bottom surface are distributed along a first predetermined angle, and at least a portion of the first pipette forms an arc shape.

In the process of the realization, the first suction pipe is contacted with the bottom surface, the first suction pipe and the bottom surface can be ensured to be distributed along a first preset angle without inclined openings, the height of the residual liquid level is reduced, meanwhile, the first suction pipe can be ensured to form an arc shape, and the first suction pipe has certain hardness and toughness, so that the first suction pipe cannot fall in the centrifugal process.

In some embodiments, a side of the second pipette remote from the second pipetting hole is configured to contact the bottom surface such that the second pipette and the bottom surface are distributed along a second predetermined angle, and at least a portion of the second pipette forms an arc shape.

In the process of the realization, the second straw is contacted with the bottom surface, so that the second straw and the bottom surface can be ensured to be distributed along a second preset angle without inclined openings, the height of the residual liquid level is reduced, the second straw can be ensured to form an arc shape, and the second straw has certain hardness and toughness, so that the second straw cannot fall in the centrifugation process.

In some embodiments, a side of the third pipette remote from the third pipetting hole is configured to be spaced apart from the bottom surface. Through setting up the third straw in the upper end of bottom surface for after whole blood carries out the centrifugation of a second time, can carry out the extraction to the anemia platelet plasma of upper strata, improve the centrifugal treatment effect to whole blood.

In some embodiments, the first pipetting hole, the second pipetting hole and the third pipetting hole are spaced apart along a pitch circle of the centrifugal structure.

In the implementation process, the first pipetting holes, the second pipetting holes and the third pipetting holes are distributed at intervals along the reference circle of the centrifugal structure, so that the distance between the first pipetting holes, the second pipetting holes and the third pipetting holes can be effectively increased, interference during installation or disassembly of the caps among the holes can be effectively avoided, and the use experience can be optimized.

In some embodiments, the centrifugal structure further comprises a tube cover configured to be connected to a side of the centrifugal body remote from the liquid collection body for enclosing to form the accommodating cavity, and the tube cover is configured with the first pipetting hole, the second pipetting hole and the third pipetting hole.

In some embodiments, the centrifugal structure further comprises a cap disposed on a side of the tube cap remote from the centrifugal body for forming a cap for the first, second, and third pipetting holes, respectively. Through be provided with the block respectively on first pipetting hole, second pipetting hole and third pipetting hole, make it possess good leakproofness, can cover first pipetting hole, second pipetting hole and third pipetting hole respectively, guarantee when not opening, can prevent effectively that the bacterium from getting into.

In some embodiments, the tube cover is provided with ventilation holes at the center or at the interval part of the pipetting holes, the center part of the cap is provided with ventilation holes, and the ventilation holes are covered with a film with functions of bacteria resistance, water resistance and ventilation.

The centrifugation method of the centrifugation device in the present application includes: s10, injecting whole blood mixed with an anticoagulant into a containing cavity of the centrifugal structure through the cooperation of the first suction tube and the first pipetting hole; s20, carrying out primary centrifugation on the whole blood in the centrifugal structure, so that a red blood cell layer after the whole blood centrifugation is discharged through the first suction tube and the first pipetting hole; s30, performing secondary centrifugation on the residual blood components in the step, and adapting a third suction tube into a third pipetting hole so as to discharge platelet-poor plasma obtained by the secondary centrifugation of the blood components; s40, extracting the residual platelet-rich plasma in the accommodating cavity through the cooperation of the second suction tube and the second pipetting hole.

In the implementation process, the first pipette is connected to the first pipette, the second pipette is connected to the second pipette, the third pipette is connected to the third pipette, when the whole blood is required to be centrifuged, the whole blood can enter the accommodating cavity of the centrifugal structure through the matching of the first pipette and the first pipette, then the whole blood is subjected to the first centrifugal treatment, the generated red blood cell layer is discharged through the first pipette and the first pipette again, the rest blood components are subjected to the second centrifugal treatment, the third pipette is assembled to the third pipette, the generated platelet-rich plasma is discharged, and finally the rest platelet-rich plasma is extracted through the second pipette, so that the platelet-rich plasma is extracted, the special purpose of the special tube is realized, the residual red blood cells are effectively prevented from being mixed into the platelet-rich plasma, and the centrifugal treatment effect on the whole blood is improved.

Additional features and advantages of the application will be set forth in the description which follows, and in part will be apparent from the description, or may be learned by practice of the embodiments of the application. The objectives and other advantages of the application will be realized and attained by the structure particularly pointed out in the written description and claims thereof as well as the appended drawings.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present application and should not be considered as limiting the scope, and that other related drawings can be obtained according to these drawings without inventive effort for the users of the art.

Fig. 1 is a schematic structural view of a centrifugal device according to an embodiment of the present application.

Fig. 2 is a top view of a centrifugal device disclosed in an embodiment of the present application.

Fig. 3 is a cross-sectional view A-A of fig. 2.

Fig. 4 is an enlarged partial schematic view of a liquid collection body of a centrifugal device according to an embodiment of the present disclosure.

Fig. 5 is an enlarged partial schematic view of fig. 3.

Fig. 6 is a schematic structural view of a third suction tube of a centrifugal device according to an embodiment of the present application.

Fig. 7 is a cross-sectional view of fig. 6.

Fig. 8 is a schematic structural view of a tube cover of a centrifugal device according to an embodiment of the present application.

Fig. 9 is a top view of a tube cover of a centrifuge device as disclosed in an embodiment of the present application.

Fig. 10 is a schematic diagram of a centrifugal device according to an embodiment of the present application.

Reference numerals

100. A centrifugal device; 101. a centrifugal structure; 1011. a first pipetting aperture; 1012. a second pipetting hole; 1013. a third pipetting hole; 1014. a centrifugal body; 1015. a liquid collection body; 10151. a straight line segment; 10152. a circular arc section; 10153. a bottom surface; 1016. a tube cover; 1017. capping; 10171. ventilation holes; 10172. a film; 1018. scale marks; 102. a straw structure; 1021. a first straw; 1022. a second straw; 1023. and a third straw.

Detailed Description

For the purposes of making the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is apparent that the described embodiments are some embodiments of the present application, but not all embodiments. The components of the embodiments of the present application, which are generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present application, as provided in the accompanying drawings, is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by a person of ordinary skill in the art based on the embodiments herein, without inventive effort are intended to be within the scope of the present application.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

In the description of the present application, it should be noted that, directions or positional relationships indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are directions or positional relationships based on those shown in the drawings, or are directions or positional relationships that are conventionally put in use of the inventive product, are merely for convenience of description of the present application and simplification of description, and do not indicate or imply that the apparatus or element to be referred to must have a specific direction, be configured and operated in a specific direction, and thus should not be construed as limiting the present application. Furthermore, the terms "first," "second," "third," and the like are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.

Furthermore, the terms "horizontal," "vertical," and the like do not denote a requirement that the component be absolutely horizontal or overhang, but rather may be slightly inclined. As "horizontal" merely means that its direction is more horizontal than "vertical", and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present application, it should also be noted that, unless explicitly specified and limited otherwise, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the terms in this application will be understood to be specific to the user of ordinary skill in the art.

Examples

Platelet Rich Plasma (PRP) is obtained by centrifugation preparation and extraction of human whole blood plasma, and is widely applied to orthopaedics, sports medicine, stomatology, plastic surgery, dermatology, ophthalmology, gynaecology and obstetrics and the like due to the characteristics of safety, no rejection and growth promotion, and the preparation method mainly comprises primary centrifugation and secondary centrifugation, wherein the PRP is obtained by the primary centrifugation, and the PRP is obtained by the secondary centrifugation in the state due to the lower concentration of the PRP blood platelet obtained by the primary centrifugation, however, the inventor discovers that in the preparation process: the existing PRP centrifuge tube has the following problems: the red blood cell separation and the PRP extraction share one pipeline, so that the concentration of red blood cells in the PRP is increased (the concentration of platelets is correspondingly reduced); the bottom structure of the tube is a hemisphere or a cone, the stable placement of the test tube is not supported, and the test tube is required to be placed by a tool in the operation process; the hole spacing of the centrifuge tube cap is smaller, so that the operation is inconvenient; the lower end of the built-in suction pipe is provided with a single-side inclined opening, and the height of the residual liquid level is consistent with the height of the opening, so that more residues exist.

In view of this, as shown in fig. 1-3, in a first aspect, the present application provides a centrifugation device 100, the centrifugation device 100 being for centrifuging whole blood, the centrifugation device 100 comprising: the centrifugal structure 101 and the straw structure 102, the straw structure 102 is connected with the pore canal of the centrifugal structure 101 (namely, the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013), so that whole blood enters into the centrifugal structure 101 through the straw structure 102, and when the whole blood is subjected to centrifugal treatment to form different products, the whole blood can be respectively extracted through the straw structure 102, thereby realizing special tube, and improving the centrifugal treatment effect of the whole blood.

Specifically, the centrifugal structure 101 has a receiving cavity configured to receive whole blood, and first, second and third pipetting holes 1011, 1012 and 1013 are provided at intervals along the periphery of the centrifugal structure 101; the pipette structure 102 includes a first pipette 1021, a second pipette 1022 and a third pipette 1023, the first pipette 1021 is configured to be connected with the first pipetting hole 1011 for injecting whole blood into the accommodating chamber and for withdrawing the erythrocyte layer after the first centrifugation of the whole blood, the second pipette 1022 is configured to be connected with the second pipetting hole 1012 for withdrawing platelet rich plasma generated after the second centrifugation of the whole blood, and the third pipette 1023 is configured to be connected with the third pipetting hole 1013 for withdrawing platelet rich plasma generated after the second centrifugation of the whole blood.

For example, the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 are all disposed at the upper end of the centrifugal structure 101, and the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 may be equidistant and located at the same radius of the distribution circle, although in other embodiments, it is not excluded that the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 are disposed at any of the upper ends of the centrifugal structure 101; it is further understood that when the first pipette 1021 is mated with the first pipetting hole 1011, the second pipette 1022 is mated with the second pipetting hole 1012, and the third pipette 1023 is mated with the third pipetting hole 1013, both the first pipette 1021 and the second pipette 1022 may be positioned within the receiving cavity of the centrifugal structure 101, and when whole blood is centrifuged a second time, at least a portion of the structure of the third pipette 1023 is positioned within the receiving cavity.

In the above implementation process, the periphery of the centrifugal structure 101 is provided with the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013, the first pipette 1021 is connected with the first pipetting hole 1011, the second pipette 1022 is connected with the second pipetting hole 1012, the third pipette 1023 is connected with the third pipetting hole, and after centrifugation, the erythrocyte layer can be discharged through the first pipette 1021, the third pipette 1023 discharges the platelet-rich plasma, and finally the platelet-rich plasma is extracted through the second pipette 1022, so that special tube can be realized, the mixing of residual erythrocytes into the platelet-rich plasma can be effectively avoided, and the centrifugal treatment effect on whole blood can be improved.

As shown in fig. 1 and 3, the centrifugal structure 101 includes a centrifugal body 1014 and a liquid collecting body 1015, the centrifugal body 1014 is connected to the liquid collecting body 1015, the first suction tube 1021 and/or the second suction tube 1022 are respectively in contact with the liquid collecting body 1015, and the liquid collecting body 1015 is configured to be contracted, so that a pipe diameter of a side of the liquid collecting body 1015 close to the centrifugal body 1014 is greater than a pipe diameter of a side of the liquid collecting body 1015 far from the centrifugal body 1015.

Illustratively, the length of the centrifugal body 1014 is configured to be distributed in the up-down direction, the centrifugal body 1014 may be provided in a transparent shape, and graduation marks 1018 may be provided along the length direction thereof, the centrifugal body 1014 is provided with the accommodating cavity, the liquid collecting body 1015 is located in the accommodating cavity, and simultaneously, in order to support the centrifugal device 100 to be stably placed without being placed by means of a fixture during the operation of the centrifugal device 100, the lower end of the centrifugal body 1014 may be provided in a planar shape; of course, in other embodiments, the lower end of the centrifugal body 1014 may be provided with an opening, and the liquid collecting body 1015 is disposed at the opening and is used to form a containing cavity with the centrifugal body 1014.

In the above implementation process, the liquid collecting body 1015 is connected with the centrifugal body 1014, and the whole blood is injected into the accommodating cavity through the first pipette 1021 and the first pipetting hole 1011, and flows to the liquid collecting body 1015, and the liquid collecting body 1015 is set to be contracted, so that the centrifugal structure 101 is beneficial to extracting the centrifuged whole blood after centrifuging the whole blood.

As shown in fig. 4, the liquid collecting body 1015 includes a straight line segment 10151, a circular arc segment 10152 and a bottom surface 10153, the circular arc segment 10152 is located between the straight line segment 10151 and the bottom surface 10153, and a side of the straight line segment 10151 away from the circular arc segment 10152 is configured to be connected with the centrifugal body 1014. The straight line segment 10151 is located at the upper end of the circular arc segment 10152, the bottom surface 10153 is located at the lower end of the circular arc segment 10152, the circular arc segment 10152 may be arranged to be tangent to the straight line segment 10151, and the straight line segment 10151, the circular arc segment 10152 and the bottom surface 10153 may be integrally formed to form a cavity with an upward opening, wherein the cavity may be arranged in a funnel shape, that is, the pipe diameter of the upper end of the liquid collecting body 1015 is larger than the pipe diameter of the lower end thereof; of course, in other embodiments, the liquid collecting body 1015 may be directly configured as an inclined surface and a bottom surface, and the inclined surface may be configured as a straight line segment 10151, or may be configured as an arc segment 10152.

In the above implementation process, the circular arc section 10152 is connected with the straight line section 10151 and the bottom surface 10153 respectively, when whole blood is injected into the accommodating cavity and centrifuged, the liquid collecting body 1015 has the straight line section 10151 and the circular arc section 10152, so that the liquid collecting body 1015 forms a contracted shape, which is beneficial to extracting the centrifuged whole blood.

As shown in fig. 5, a side of the first pipette 1021 away from the first pipetting hole 1011 is configured to contact the bottom surface 10153 such that the first pipette 1021 and the bottom surface 10153 are distributed along a first predetermined angle, and at least a portion of the structure of the first pipette 1021 forms an arc shape. For example, the length of the first suction tube 1021 may be set to be consistent with the length of the centrifugal body 1014, or may be set to be greater than the length of the centrifugal body 1014, although it is not excluded that the length of the first suction tube 1021 and the first pipetting hole 1011 are set to be smaller than the length of the centrifugal body, wherein the first suction tube 1021 is pressed into an arc shape after the lower end of the first suction tube 1021 contacts the bottom surface 10153 due to the fact that the liquid collection body 1015 is configured to be contracted during the actual assembly, and the lower end of the first suction tube 1021 and the bottom surface 10153 form an included angle with a first preset angle, and the first preset angle is an acute angle, for example, the first preset angle may be set between 10 ° and 50 °, etc.; in order to facilitate the aspiration of the bottom erythrocyte layer in whole blood, the lower end of the first pipette 1021 may be further provided with a chamfer opening, which may be provided with two, three, or four chamfer openings, and the specific position of the chamfer opening is not particularly limited.

In the above implementation process, the first suction tube 1021 contacts with the bottom surface 10153, so that the first suction tube 1021 and the bottom surface 10153 can be ensured to be distributed along the first preset angle, no inclined opening is needed, the height of the residual liquid level is reduced, meanwhile, the first suction tube 1021 can be ensured to form an arc shape, and the first suction tube 1021 is ensured to not fall in the centrifugation process due to certain hardness and toughness.

Referring to fig. 5 again, a side of the second pipette 1022 away from the second pipetting hole 1012 is configured to contact the bottom surface 10153 such that the second pipette 1022 and the bottom surface 10153 are distributed along a second predetermined angle, and at least a portion of the second pipette 1022 forms an arc shape. For example, the length of the second suction tube 1022 may be set to be consistent with the length of the centrifugal body 1014, or may be set to be greater than the length of the centrifugal body 1014, or it is not excluded that the length of the second suction tube 1022 is set to be smaller than the length of the centrifugal body, wherein the second suction tube 1022 and the second pipetting hole 1012 are arranged in a contracted form during the actual assembly process, such that the second suction tube 1022 is pressed into an arc shape after the lower end of the second suction tube 1022 contacts the bottom surface 10153, and the lower end of the second suction tube 1022 forms an included angle with the bottom surface 10153, the second predetermined angle is an acute angle, for example, the second predetermined angle may be set between 10 ° and 50 °, etc.; in order to facilitate the suction of the platelet-rich plasma after the secondary centrifugation, the lower end of the second pipette 1022 may further be provided with a chamfer opening, which may be provided with two, three, or four chamfer openings, and the specific position of the chamfer opening is not particularly limited.

In the above implementation process, the second suction pipe 1022 contacts with the bottom surface 10153, so that the second suction pipe 1022 and the bottom surface 10153 can be ensured to be distributed along the second preset angle, no inclined opening is needed, the height of the residual liquid level is reduced, meanwhile, the second suction pipe 1022 can be ensured to form an arc shape, and the second suction pipe 1022 has certain hardness and toughness, so that the second suction pipe 1022 is beneficial to not falling in the centrifugation process.

As shown in fig. 6 to 7, a side of the third pipette 1023 away from the third pipetting hole 1013 is disposed to be spaced apart from the bottom surface 10153, that is, a gap exists between the lower end of the third pipette 1023 and the bottom surface 10153, and the length of the third pipette 1023 can be set according to the practical application, which is not limited herein. By arranging the third straw 1023 at the upper end of the bottom surface 10153, after the whole blood is centrifuged for the second time, the platelet-poor plasma on the upper layer can be extracted, and the centrifugation effect on the whole blood is improved.

Referring to fig. 2 again, the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 are distributed at intervals along a reference circle of the centrifugal structure 101, wherein specific positions of the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 distributed in the distribution circle are not particularly limited, and the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013 are distributed at intervals along the reference circle of the centrifugal structure 101, so that the distance between the three can be effectively increased, interference during mounting or dismounting of the cap 1017 between the holes can be effectively avoided, and the use experience can be optimized.

As shown in fig. 8-9, the centrifugal structure 101 further includes a tube cap 1016, wherein the tube cap 1016 is configured to be connected to a side of the centrifugal body 1014 away from the liquid collecting body 1015, for enclosing to form a containing cavity, and the tube cap 1016 is configured to have a first pipetting hole 1011, a second pipetting hole 1012, and a third pipetting hole 1013; wherein the tube cap 1016 and the upper end of the centrifuge body 1014 may be secured by glue, threaded connection, ultrasonic welding, or the like.

Referring to fig. 1 or 3, the centrifugal structure 101 further includes a cap 1017, where the cap 1017 is disposed on a side of the tube cap 1016 away from the centrifugal body 1014, so as to cover the first pipetting hole 1011, the second pipetting hole 1012, and the third pipetting hole 1013, respectively; the cap 1017 is provided with ventilation holes 10171 along the up-down direction thereof, for example, the tube cap 1016 is provided with ventilation holes 10171 at the center or the interval part of the pipetting holes (namely, the first pipetting hole 1011, the second pipetting hole 1012 and the third pipetting hole 1013), the center part of the cap is provided with ventilation holes 10171, the ventilation holes 10171 can be covered by a film 10172, wherein the film 10172 has the functions of water resistance, ventilation and bacteria resistance, and the connection mode of the cap 1017 and the tube cap 1016 can be screw connection or detachable sealing connection such as snap connection. Through be provided with the block 1017 on first pipetting hole 1011, second pipetting hole 1012 and third pipetting hole 1013 respectively, it possesses good leakproofness, can cover first pipetting hole 1011, second pipetting hole 1012 and third pipetting hole 1013 respectively, guarantees when not opening, can prevent effectively that the bacterium from getting into.

As shown in fig. 10, in a second aspect, the present application further provides a centrifugation method, which is applied to the above-described centrifugation apparatus 100, the centrifugation method including: s10, injecting whole blood mixed with an anticoagulant into a containing cavity of the centrifugal structure 101 through the cooperation of the first suction tube 1021 and the first pipetting hole 1011; s20, performing primary centrifugation on the whole blood in the centrifugal structure 101, so that a red blood cell layer after the whole blood centrifugation is discharged through the first suction tube 1021 and the first pipetting hole 1011; s30, performing secondary centrifugation on the residual blood components in the step, and fitting a third straw 1023 into the third pipetting hole 1013 so as to discharge platelet-poor plasma obtained by the secondary centrifugation of the blood components; s40, extracting the residual platelet-rich plasma in the accommodating cavity through the cooperation of the second suction tube 1022 and the second pipetting hole 1012; when the whole blood is required to be centrifuged, the whole blood can enter the accommodating cavity of the centrifugal structure 101 through the matching of the first pipette 1021 and the first pipette 1011, then the whole blood is subjected to the first centrifugation, the generated red blood cell layer is discharged through the first pipette 1011 and the first pipette 1021 again, the rest whole blood is subjected to the second centrifugation, the third pipette 1023 is assembled at the third pipette 1013, the generated platelet-rich plasma is discharged, and finally the rest platelet-rich plasma is discharged by the second pipette 1022, so that the special tube is realized, the mixing of the rest red blood cells into the platelet-rich plasma is effectively avoided, and the centrifugation effect on the whole blood is improved.

The foregoing description is only of the preferred embodiments of the present application and is not intended to limit the same, but rather, various modifications and variations may be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims (10)

1. A centrifugal apparatus, comprising:

a centrifugal structure, which is provided with a containing cavity, wherein the containing cavity is used for containing whole blood, and a first pipetting hole, a second pipetting hole and a third pipetting hole are arranged at intervals along the periphery of the centrifugal structure;

a pipette structure comprising a first pipette configured to be connected with the first pipetting hole for injecting the whole blood into the receiving cavity and withdrawing a red blood cell layer after the first centrifugation of the whole blood, a second pipette configured to be connected with the second pipetting hole for withdrawing platelet rich plasma generated after the second centrifugation of the whole blood, and a third pipette configured to be passed through the third pipetting hole for withdrawing platelet rich plasma generated after the second centrifugation of the whole blood.

2. A centrifugal device according to claim 1, wherein the centrifugal structure comprises a centrifugal body and a liquid collecting body, the centrifugal body is connected with the liquid collecting body, the first suction pipe and/or the second suction pipe are/is respectively contacted with the liquid collecting body, and the liquid collecting body is arranged in a contracted shape, so that the pipe diameter of one side of the liquid collecting body, which is close to the centrifugal body, is larger than the pipe diameter of one side, which is far away from the centrifugal body.

3. The centrifugal device of claim 2, wherein the liquid collection body comprises a straight line segment, an arc segment and a bottom surface, the arc segment is located between the straight line segment and the bottom surface, and a side of the straight line segment away from the arc segment is configured to be connected with the centrifugal body.

4. A centrifugation device as claimed in claim 3, wherein the side of the first pipette remote from the first pipetting hole is arranged in contact with the bottom surface such that the first pipette and the bottom surface are distributed along a first predetermined angle and at least part of the structure of the first pipette forms an arc shape.

5. The centrifugation device according to claim 3 or 4, wherein a side of the second suction tube remote from the second pipetting hole is configured to be in contact with the bottom surface such that the second suction tube is distributed along a second predetermined angle with the bottom surface, and at least a portion of the second suction tube forms an arc shape.

6. A centrifugation device as claimed in claim 3, wherein the side of the third pipette remote from the third pipetting aperture is arranged spaced apart from the bottom surface.

7. The centrifuge of claim 1 wherein said first pipetting hole, said second pipetting hole and said third pipetting hole are spaced apart along a pitch circle of said centrifuge structure.

8. The centrifuge of claim 2, further comprising a tube cover configured to connect with a side of the centrifuge body remote from the liquid collection body for enclosing the receiving cavity, and wherein the tube cover is configured with the first, second, and third pipetting holes.

9. The centrifuge of claim 8, further comprising a cap disposed on a side of said tube cap remote from said centrifuge body for covering said first, second and third pipetting holes, respectively.

10. The centrifugal device according to claim 9, wherein the tube cover is provided with ventilation holes at the center or at the interval between the pipetting holes, the cap is provided with ventilation holes at the center, and the ventilation holes are covered with a film having functions of bacteria resistance, water resistance and ventilation.

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