CN219015806U - Chip fixing carrier for cell capturing and dyeing - Google Patents

Chip fixing carrier for cell capturing and dyeing Download PDF

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Publication number
CN219015806U
CN219015806U CN202223571783.8U CN202223571783U CN219015806U CN 219015806 U CN219015806 U CN 219015806U CN 202223571783 U CN202223571783 U CN 202223571783U CN 219015806 U CN219015806 U CN 219015806U
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China
Prior art keywords
plate
chip
side plates
mounting seat
cell capture
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CN202223571783.8U
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Chinese (zh)
Inventor
任阳杰
沈洪飞
郭剑
郑思寒
陈跃东
顾志鹏
王春明
范兆飞
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Xiamen Deyun Xinzhun Technology Co ltd
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Xiamen Deyun Xinzhun Technology Co ltd
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Priority to CN202223571783.8U priority Critical patent/CN219015806U/en
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Abstract

The utility model discloses a chip fixing carrier for cell capturing and staining. The carrying platform comprises a bottom plate, a sliding plate, a mounting seat, two pin shafts, a pressing plate and a stepping motor, wherein two sides of the bottom plate are respectively provided with two vertical side plates, a vertical back plate is arranged at the rear end of the bottom plate, two sides of the sliding plate are respectively and slidably mounted on the two side plates, the mounting seat is positioned above the sliding plate, the two vertical pin shafts are movably connected with the sliding plate and the mounting seat through shaft sleeves, two sides of the pressing plate are respectively and movably mounted above the two side plates, the stepping motor is connected with a belt pulley transmission structure, and the belt pulley transmission structure is connected with a connecting block. The chip fixing carrier for cell capturing and dyeing uses the chip base to mount the chip, and can clamp, relax and adjust the position of the chip base, thereby ensuring the accuracy and stability of the mounting position of the chip and improving the accuracy and efficiency of the cell capturing and dyeing experiment.

Description

Chip fixing carrier for cell capturing and dyeing
Technical Field
The utility model relates to the field of medical experimental equipment, in particular to a chip fixing carrier for cell capturing and dyeing.
Background
The cell capturing and staining is to inject a sample into the chip, adsorb the cells in the channel structure layer in a specific capturing mode, and then stain the cells by using a staining reagent, so that the cells can display required fluorescence under a scanner. In the process of injecting the sample into the chip, the sampling needle which absorbs the sample needs to be aligned with the chip, and if errors occur in the position of the chip due to unstable fixation and the like, the accuracy and the efficiency of the experiment can be affected.
Disclosure of Invention
In order to solve the problems, the utility model provides a chip fixing carrier for cell capturing and staining.
According to one aspect of the present utility model, there is provided a chip immobilization carrier for cell capture staining, comprising:
the device comprises a bottom plate, wherein two sides of the bottom plate are respectively provided with two vertical side plates, and a vertical backboard is arranged at the rear end of the bottom plate;
the two sides of the sliding plate are respectively and slidably arranged on the two side plates;
the two ends of the mounting seat are respectively and slidably arranged on the inner side surfaces of the two side plates, and the mounting seat is positioned above the sliding plate;
the two vertical pin shafts are movably connected with the sliding plate and the mounting seat through shaft sleeves, and the bottom ends of the two pin shafts are connected through a connecting block;
the two sides of the pressing plate are respectively movably arranged at the tops of the two side plates, and the middle part of the pressing plate is provided with a hollow top groove;
the stepping motor is connected with a horizontally extending belt pulley transmission structure, and the belt pulley transmission structure is connected with the connecting block;
and the top plate is positioned between the sliding plate and the mounting seat, and is slidably mounted on the back plate.
In some embodiments, two sliding grooves with different heights at two ends are arranged on two side plates, bearing screws are arranged at two ends of each side of the sliding plate, and each bearing screw is respectively and slidably arranged in each sliding groove. The sliding plate has the advantages that the concrete structure that the sliding plate is slidably arranged on the two side plates is described.
In some embodiments, two horizontal guide rails are respectively mounted on the inner sides of the two side plates, and two ends of the mounting seat are respectively and slidably mounted on the two horizontal guide rails. The mounting seat has the advantages that the specific structure that the mounting seat is slidably mounted on the two side plates is described.
In some embodiments, the interior of the base plate is hollow and is fitted with at least one upwardly facing off-bin sensor. The bin outlet sensor is beneficial in that the bin outlet sensor can be used for detecting the sliding condition of the mounting seat.
In some embodiments, the mount includes a base and a blade mounted on the base, the blade for mounting a chip. The mounting seat has the advantages that the specific structure of the mounting seat is described.
In some embodiments, two ends of each side of the pressing plate are movably mounted on the tops of the two side plates through screws sleeved with springs, and the top groove is located right above the central part of the chip. The beneficial effect is that the concrete mode of installing the pressing plate on the top of the two side plates is described.
In some embodiments, a limiting plate is mounted on top of both side plates, and the limiting plate extends into the base and contacts the supporting plate. The limiting plate is arranged to limit the chip from the side face.
In some embodiments, the limiting plate is provided with a pressing sensor facing the pressing plate. The pressing device has the advantages that the pressing sensor is arranged and can detect the pressing condition of the pressing plate.
In some embodiments, a vertical rail is mounted to the back plate, and the top plate is slidably mounted to the vertical rail. This is beneficial in that it describes the specific manner in which the top plate is slidably mounted on the back plate.
In some embodiments, the top of the top plate has a plurality of posts. The top plate is beneficial in that the top plate can jack the mounting seat through the jack post.
Drawings
FIG. 1 is a schematic diagram showing a chip mounting stage for cell capture staining according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram of the related structure of the base plate shown in FIG. 1;
FIG. 3 is a schematic view of the platen shown in FIG. 1;
FIG. 4 is a schematic diagram of the structure of FIG. 1 after removal of the substrate and platen associated structures from a chip mounting stage for cell capture staining.
In the figure: the device comprises a bottom plate 1, a sliding plate 2, a mounting seat 3, a pin shaft 4, a pressing plate 5, a stepping motor 6, a top plate 7, a chip 8, a side plate 11, a back plate 12, a sliding groove 13, a horizontal guide rail 14, a discharging sensor 15, a vertical guide rail 16, a wire inserting fixing plate 17, a bearing screw 21, a base 31, a supporting plate 32, a connecting block 41, a top groove 51, a screw 52, a limiting plate 53, a material pressing sensor 54, a belt pulley transmission structure 61 and a top column 71.
Detailed Description
The utility model is described in further detail below with reference to the accompanying drawings.
Fig. 1 schematically shows a structure of a chip-mounting stage for cell capture staining according to an embodiment of the present utility model, fig. 2 shows a related structure of a bottom plate in fig. 1, fig. 3 shows a related structure of a platen in fig. 1, and fig. 4 shows a structure of a chip-mounting stage for cell capture staining in fig. 1 after removing the bottom plate and the platen related structure.
As shown in fig. 1 to 4, the carrier comprises a bottom plate 1 horizontally arranged, two vertical side plates 11 are respectively arranged on two sides of the bottom plate 1, a vertical back plate 12 is arranged at the other end (set as a rear end) of the bottom plate 1, and other main structures including a sliding plate 2, a mounting seat 3, two pin shafts 4, a pressing plate 5, a stepping motor 6, a top plate 7 and the like are directly or indirectly arranged on the bottom plate 1, the side plates 11 and the back plate 12.
The slide plate 2 extends in a substantially horizontal direction, and is provided with bearing screws 21 at both ends of each side thereof, i.e. four bearing screws 21 in total, and two slide grooves 13 are provided on both side plates 11, i.e. four slide grooves 13 in total, and the four bearing screws 21 are slidably mounted in the four slide grooves 13, respectively, so that the slide plate 2 is slidably mounted on both side plates 11. Wherein, the heights of the two ends of the sliding groove 13 are different, and the height of the rear end is higher than the front end, the height of the sliding plate 2 can be reduced when the sliding plate slides forwards, and the height can be increased when the sliding plate slides backwards.
Further, considering the length of the side plates 11, the front end of the slide groove 13 located at the front on each side plate 11 may be opened so that the slide plate 2 can slide out of the front end of the side plate 11 by a sufficient length, and since the slide groove 13 located at the rear is a closed loop, the slide plate 2 does not slide out of the side plate 11.
The mounting seat 3 is horizontally arranged and is positioned above the sliding plate 2, and two ends of the mounting seat are respectively and slidably arranged on the two side plates 11 through two horizontal guide rails 14 arranged on the inner sides of the two side plates 11. The mounting seat 3 is connected with the sliding plate 2 through two vertical pin shafts 4, specifically, the mounting seat 3 and the sliding plate 2 are movably connected with the two pin shafts 4 through shaft sleeves, and then the mounting seat 3 can slide and lift along the pin shafts 4 and can also horizontally slide outside the front end of the side plate 11 along with the sliding plate 2.
The mounting base 3 comprises a base 31 and a pallet 32, wherein the base 31 is slidably mounted on the horizontal rail 14 and connected to the two pins 4, and the pallet 32 is mounted on the base 31 and the pallet 32 is used for mounting the chip 8.
In addition, a groove for collecting waste liquid is provided in the middle of the pallet 32, facilitating the discharge and recovery of waste liquid.
The stepper motor 6 is mounted at the bottom of the base plate 1, and the stepper motor 6 is connected with a horizontally extending belt pulley transmission structure 61 (comprising a horizontally extending transmission belt and two rotating wheels), while the bottom ends of the two pin shafts 4 are connected through a connecting block 41, and the transmission belt of the belt pulley transmission structure 61 is fixedly connected with the connecting block 41. Thus, the stepper motor 6 can drive the connecting block 41 and the two pins 4 to move horizontally through the pulley transmission structure 61, and further drive the slide plate 2 and the mounting seat 3 to slide horizontally.
The inside of the base plate 1 is hollow, and at least one discharge sensor 15 is installed in the hollow portion thereof, and the discharge sensor 15 faces the slide plate 2 above it, so that it is possible to detect the horizontal sliding of the slide plate 2 and the mount 3.
In addition, a wire inserting fixing board 17 is connected to the bottom of the base plate 1, and can be used for installing a patch board.
The two ends of each side of the pressing plate 5 are respectively provided with a screw 52 with a spring sleeved outside, namely four screws 52 are arranged, the pressing plate 5 is movably arranged at the top of the two side plates 11 through each screw 52, a hollow top groove 51 is arranged in the middle of the pressing plate 5, and the size of the top groove 51 is slightly smaller than the upper surface of the chip 8. When the chip 8 is mounted on the pallet 32 of the mounting base 3, the top groove 51 is located directly above the center of the chip 8, that is, the pressing plate 5 can press the chip 8, and the center of the chip 8 is exposed through the top groove 51.
And a limiting plate 53 is also mounted on the top of the two side plates 11, the limiting plate 53 is located on the side surface of the pressing plate 5, the front end of the limiting plate 53 extends out of the pressing bar, and the pressing bar can extend into the base 31 and contact with the supporting plate 32, so that the supporting plate 32 and the chip 8 thereon are limited from the side surface.
In addition, a pressing sensor 54 is mounted on the limiting plate 53, and the pressing sensor 54 faces the pressing plate 5, so that the pressing condition of the pressing plate 5 can be detected.
The top plate 7 is located between the slide plate 2 and the mounting base 3 and also between the two pins 4 and is not in contact with the two pins 4, and the rear end of the top plate 7 is slidably mounted on the back plate 12. Wherein, a vertical guide rail 16 is arranged on the back plate 12, the rear end of the top plate 7 is slidably arranged on the vertical guide rail 16, and the top plate 7 can be lifted and lowered along the vertical guide rail 16 under the action of a proper power mechanism.
And a plurality of jacking posts 71 are arranged on the top of the top plate 7, and the propped top ends can be contacted with the base 31 of the mounting seat 3, so that the mounting seat 3 and the chip 8 mounted on the mounting seat 3 are jacked.
When the carrier is used, the stepping motor 6 slides out of the front ends of the side plates 11 through the belt pulley transmission structure 61 and the pin shaft 4 with the sliding plate 2 and the mounting seat 3, then the chip 8 is placed on the supporting plate 32 on the mounting seat 3 through other equipment, and the stepping motor 6 reversely operates to enable the sliding plate 2 and the mounting seat 3 to slide between the two side plates 11; then, the top plate 7 is lifted upwards, the top posts 71 on the top plate lift the mounting seat 3 and the chip 8, and the pressing plate 5 above the chip 8 is stressed to press the chip 8, so that the chip 8 is clamped and fixed; finally, the cell capturing and staining experiment can be performed on the chip 8, and after the experiment is completed, the operation is performed reversely, and the chip 8 is loosened, slipped out and collected in sequence.
What has been described above is merely some embodiments of the present utility model. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit of the utility model.

Claims (10)

1. A chip-immobilized carrier for cell capture staining, characterized by: comprising
The device comprises a bottom plate (1), wherein two sides of the bottom plate (1) are respectively provided with two vertical side plates (11), and a vertical backboard (12) is arranged at the rear end of the bottom plate (1);
the two sides of the sliding plate (2) are respectively and slidably arranged on the two side plates (11);
the two ends of the mounting seat (3) are respectively and slidably arranged on the inner side surfaces of the two side plates (11), and the mounting seat (3) is positioned above the sliding plate (2);
the two vertical pin shafts (4) are movably connected with the sliding plate (2) and the mounting seat (3) through shaft sleeves, and the bottom ends of the two pin shafts (4) are connected through a connecting block (41);
the two sides of the pressing plate (5) are respectively and movably arranged at the tops of the two side plates (11), and the middle part of the pressing plate (5) is provided with a hollow top groove (51);
the stepping motor (6) is arranged at the bottom of the bottom plate (1), and is connected with a horizontally extending belt pulley transmission structure (61), and the belt pulley transmission structure (61) is connected with the connecting block (41);
a top plate (7), wherein the top plate (7) is positioned between the sliding plate (2) and the mounting seat (3), and the top plate (7) is slidably mounted on the back plate (12).
2. A chip mounting carrier for cell capture staining according to claim 1, wherein: two sliding grooves (13) with different heights at two ends are formed in the two side plates (11), bearing screws (21) are mounted at two ends of each side of the sliding plate (2), and the bearing screws (21) are slidably mounted in the sliding grooves (13) respectively.
3. A chip mounting carrier for cell capture staining according to claim 1, wherein: two horizontal guide rails (14) are respectively arranged on the inner side surfaces of the two side plates (11), and two ends of the mounting seat (3) are respectively and slidably arranged on the two horizontal guide rails (14).
4. A chip mounting carrier for cell capture staining according to claim 1, wherein: the interior of the base plate (1) is hollow and is equipped with at least one upward-facing discharge sensor (15).
5. A chip mounting carrier for cell capture staining according to claim 1, wherein: the mounting base (3) comprises a base (31) and a supporting plate (32), wherein the supporting plate (32) is mounted on the base (31), and the supporting plate (32) is used for mounting the chip (8).
6. A chip mounting platform for cell capture staining according to claim 5, wherein: the two ends of each side of the pressing plate (5) are movably mounted at the tops of the two side plates (11) through screws (52) sleeved with springs, and the top groove (51) is located right above the center of the chip (8).
7. A chip mounting platform for cell capture staining according to claim 6, wherein: a limiting plate (53) is mounted on the top of the two side plates (11), and the limiting plate (53) extends into the base (31) and is in contact with the supporting plate (32).
8. A chip mounting platform for cell capture staining according to claim 7, wherein: the limiting plate (53) is provided with a pressing sensor (54) facing the pressing plate (5).
9. A chip mounting carrier for cell capture staining according to claim 1, wherein: the backboard (12) is provided with a vertical guide rail (16), and the top plate (7) is slidably arranged on the vertical guide rail (16).
10. A chip mounting carrier for cell capture staining according to claim 1, wherein: the top of the top plate (7) is provided with a plurality of top posts (71).
CN202223571783.8U 2022-12-28 2022-12-28 Chip fixing carrier for cell capturing and dyeing Active CN219015806U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223571783.8U CN219015806U (en) 2022-12-28 2022-12-28 Chip fixing carrier for cell capturing and dyeing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223571783.8U CN219015806U (en) 2022-12-28 2022-12-28 Chip fixing carrier for cell capturing and dyeing

Publications (1)

Publication Number Publication Date
CN219015806U true CN219015806U (en) 2023-05-12

Family

ID=86250083

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223571783.8U Active CN219015806U (en) 2022-12-28 2022-12-28 Chip fixing carrier for cell capturing and dyeing

Country Status (1)

Country Link
CN (1) CN219015806U (en)

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