CN218870575U - Heart perfusion needle for animal heart perfusion experiment - Google Patents

Heart perfusion needle for animal heart perfusion experiment Download PDF

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Publication number
CN218870575U
CN218870575U CN202222757791.5U CN202222757791U CN218870575U CN 218870575 U CN218870575 U CN 218870575U CN 202222757791 U CN202222757791 U CN 202222757791U CN 218870575 U CN218870575 U CN 218870575U
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needle
heart perfusion
perfusion
heart
animal
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CN202222757791.5U
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王雪峰
陈鹏
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Nantong Yaomingkant Pharmaceutical Technology Co ltd
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Nantong Yaomingkant Pharmaceutical Technology Co ltd
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Abstract

The utility model discloses a heart perfusion needle for animal heart perfusion experiments, which comprises an anti-drop heart perfusion needle head, a needle head pipe body and a needle cylinder connecting base which are connected in sequence, wherein the anti-drop heart perfusion needle head is sleeved with a needle point anti-drop sleeve, and one side of the needle head pipe body, which is close to the anti-drop heart perfusion needle head, is sleeved with a rear positioning ring; the ventricular puncture needle can keep a fixed position after effectively puncturing a ventricle, has certain traction resistance and is not easy to fall off; the perfusion tube can be flexibly fixed by adopting the fixing seat with the universal tube, so that the falling-off prevention heart perfusion needle is further prevented from falling off in the perfusion process, and the fixation of the falling-off prevention heart perfusion needle is assisted; the automatic and rapid liquid changing perfusion pump is adopted, so that the liquid changing operation in a perfusion experiment is simplified, and the problem of bubble generation in manual liquid changing operation is solved; the failure rate of the heart perfusion experiment can be greatly reduced.

Description

Heart perfusion needle for animal heart perfusion experiment
Technical Field
The utility model relates to a heart perfusion needle field for the experiment, concretely relates to heart perfusion needle for animal heart perfusion experiment.
Background
The heart perfusion experiment is an essential first step in animal tissue material drawing, the perfusion effect directly influences the state of the tissue and is vital to the success of experiments such as tissue staining, the heart perfusion experiment firstly needs to expose the animal heart, insert the perfusion needle into the left ventricle of the animal, fix the perfusion needle, cut the right auricle and carry out perfusion of normal saline and paraformaldehyde in sequence;
the difficult point in the heart perfusion experiment is that the key point of causing experiment failure is that not only the perfusion needle is inserted into the left ventricle, but also the insertion position is kept in the whole perfusion process, if the perfusion needle is excessively inserted, the ventricle is pierced, and the ventricle is separated from the ventricle after the perfusion needle is moved backwards, so that the perfusion liquid can not enter the tissues of the whole body through the vascular circulation system of the animal under both conditions, and the experiment irreversible failure is caused; in the experiment, the animal can vibrate the whole body due to the formaldehyde perfusion, and the hydraulic pressure of the perfusion liquid can generate reaction force and vibration to the perfusion needle, so that the steps are very tested on the experience and the manipulation of experimenters;
there is not dedicated animal heart perfusion device in the existing market, and the laboratory technician mostly adopts ordinary syringe needle and hose for injection or infusion, and the syringe needle is fixed or is directly fixed perfusion needle through sticky tape adhesion with using the vascular pincers after inserting the heart, adopts ordinary syringe needle for injection or infusion to have following unable shortcoming of overcoming: firstly, because the ventricle needs to be penetrated smoothly, a sharp needle head is needed, but the requirement for grasping the needle inserting distance of an experimenter is high, and the experiment fails once too much or insufficient needle inserting is performed; secondly, the blood vessel forceps or the adhesive tape is needed for fixation, and small animals with small hearts, such as mice, young rats and the like, are difficult to succeed at one time, usually need multiple attempts, not only waste time, but also possibly cause the perfusion needle to be separated due to operation; thirdly, the fixation of the vascular clamp needs to directly clamp the ventricle and the perfusion needle, which is easy to cause irreversible mechanical damage to the heart tissue, resulting in the outflow of perfusion liquid.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that the perfusion needle is separated or penetrated in transition to cause perfusion failure in animal heart perfusion experiments, the utility model provides a heart perfusion needle for animal heart perfusion experiments, which adopts an anti-drop heart perfusion needle provided with a needle point anti-drop sleeve, a needle head tube body and a rear positioning ring, can keep fixed position after effectively penetrating into a ventricle, has certain anti-drawing capability and is not easy to separate; the perfusion tube can be flexibly fixed by adopting the fixing seat with the universal tube, so that the falling-off prevention heart perfusion needle is further prevented from falling off in the perfusion process, and the fixation of the falling-off prevention heart perfusion needle is assisted; the automatic and rapid liquid changing perfusion pump is adopted, so that the liquid changing operation in a perfusion experiment is simplified, and the problem of bubble generation in manual liquid changing operation is solved; the failure rate of the heart perfusion experiment can be greatly reduced, the occupation of the experiment on the personnel time is greatly improved, the experiment efficiency is greatly submitted, and the defects caused by the prior art are overcome.
In order to solve the technical problem, the utility model provides a following technical scheme:
the utility model provides an animal heart perfusion experiment is with heart perfusion needle, wherein, contains the anticreep heart perfusion syringe needle, syringe needle body, the cylinder connection base that connect gradually, the cover is equipped with needle point anticreep sleeve pipe on the anticreep heart perfusion syringe needle, the syringe needle body is close one side cover of anticreep heart perfusion syringe needle is equipped with the rear holding ring.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the length of the needle head tube body is 10-100mm, the outer diameter of the needle head tube body is 0.4-1.5mm, and the outer diameter of the needle head tube body is consistent with the inner diameter of the needle point anti-falling sleeve.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the front end of the needle tip anti-falling sleeve is a beveled needle tip with an angle of 15-30 degrees, and the tail end of the needle tip anti-falling sleeve is a beveled barb with an angle of 15-30 degrees.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the needle point anti-falling sleeve is 1-2mm long, 0.8-2mm in outer diameter and 0.4-1.5mm in inner diameter.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the distance between the rear positioning ring and the front end of the needle head tube body is 3-7mm, and the distance between the rear positioning ring and the tail end of the needle point anti-falling sleeve is 1-3mm.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the outer diameter of the rear positioning ring is 2-4mm, and the inner diameter of the rear positioning ring is consistent with the outer diameter of the needle head tube body.
In the heart perfusion needle for animal heart perfusion experiments, the rear positioning ring is a circular ring made of metal or plastic.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the needle cylinder connecting base is a standard luer connector.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the needle head tube body and the needle point anti-drop sleeve are both made of medical stainless steel materials, and the needle cylinder connecting base is made of medical plastics or medical stainless steel materials.
The heart perfusion needle for the animal heart perfusion experiment has the following effects:
firstly, the puncturing process does not need precise needle insertion depth control any more, so that the experimenter does not need to pay high attention;
secondly, after the puncture, the anti-falling heart perfusion needle can be fixed in the left ventricle to a certain degree under the action of the oblique barb, so that additional fixation of hemostats or adhesive tapes is not needed, experimental steps are saved, meanwhile, experimenters are not required to control the position of the anti-falling heart perfusion needle by one hand and the other hand is not required to perform fixation operation, and the probability of falling-off of the needle is greatly reduced;
thirdly, due to the fixing effect of the oblique-cutting barb, the problem of needle head falling-out caused by perfusion speed, needle head vibration and the like during perfusion is basically solved;
fourthly, the difficulty of the animal heart perfusion experiment is greatly reduced, and experimenters can conveniently and quickly get on hand.
According to above-mentioned the utility model relates to a technical scheme that animal heart perfusion experiment heart perfusion needle provided has following technological effect:
the anti-drop heart perfusion needle provided with the needle point anti-drop sleeve, the needle head tube body and the rear positioning ring can keep fixed after effectively penetrating into a ventricle, has certain traction resistance and is not easy to drop; the perfusion tube can be flexibly fixed by adopting the fixing seat with the universal tube, so that the falling-off prevention heart perfusion needle is further prevented from falling off in the perfusion process, and the fixation of the falling-off prevention heart perfusion needle is assisted; the automatic and rapid liquid changing perfusion pump is adopted, so that the liquid changing operation in a perfusion experiment is simplified, and the problem of bubbles generated in manual liquid changing operation is solved; the failure rate of the heart perfusion experiment can be greatly reduced, the occupation of the experiment on the personnel time is greatly improved, and the experiment efficiency is greatly improved.
Drawings
Fig. 1 is a schematic structural view of a heart perfusion needle for animal heart perfusion experiments.
Wherein the reference numbers are as follows:
1. a drop-proof heart perfusion needle head; 2. a needle body; 3. the needle cylinder is connected with the base; 4. a needle tip anti-drop sleeve; 5. and a rear positioning ring.
Detailed Description
In order to make the technical means, the inventive features, the objectives, and the functions of the present invention easy to understand and understand, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings.
Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be understood that the structure, ratio, size and the like shown in the drawings attached to the present specification are only used for matching with the content disclosed in the specification, so as to be known and read by those skilled in the art, and are not used for limiting the limit conditions that the present invention can be implemented, so that the present invention has no technical essential meaning, and any structure modification, ratio relationship change or size adjustment should still fall within the scope that the technical content disclosed in the present invention can cover without affecting the function that the present invention can produce and the purpose that the present invention can achieve.
Meanwhile, the terms such as "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for convenience of description, and are not intended to limit the scope of the present invention, and changes or adjustments of the relative relationship thereof may be made without substantial technical changes, and the present invention is also regarded as the scope of the present invention.
The first embodiment of the utility model provides a heart perfusion needle for animal heart perfusion experiments, which aims to adopt an anti-drop heart perfusion needle provided with a needle point anti-drop sleeve, a needle head tube body and a rear positioning ring, can keep the position fixed after effectively penetrating into a ventricle, has certain anti-drawing capability and is not easy to drop; the fixing seat with the universal pipe is adopted, so that the perfusion tube can be flexibly fixed, the falling-off prevention heart perfusion needle is further prevented from falling off in the perfusion process, and the falling-off prevention heart perfusion needle is assisted to be fixed; the automatic and rapid liquid changing perfusion pump is adopted, so that the liquid changing operation in a perfusion experiment is simplified, and the problem of bubbles generated in manual liquid changing operation is solved; the failure rate of the heart perfusion experiment can be greatly reduced, the occupation of the experiment on the personnel time is greatly improved, and the experiment efficiency is greatly improved.
As shown in fig. 1, a heart perfusion needle for animal heart perfusion experiments, wherein, contain anticreep heart perfusion syringe needle, syringe needle body, the cylinder connection base that connects gradually, the cover is equipped with needle point anticreep sleeve pipe on the anticreep heart perfusion syringe needle, the syringe needle body is nearly one side cover of anticreep heart perfusion syringe needle is equipped with the rear holding ring.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the length of the needle head tube body is 10-100mm, the outer diameter of the needle head tube body is 0.4-1.5mm, the outer diameter of the needle head tube body is consistent with the inner diameter of the needle point anti-falling sleeve, the needle head tube body is made of medical stainless steel, the structure of the heart perfusion needle is similar to that of a common needle tube, and the needle head tube body needs to be consistent with the inner diameter of the needle point anti-falling sleeve according to a use scene, namely the size of an animal heart and the thickness of a ventricular wall.
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the front end of the needle point anti-falling sleeve is a 15-30-degree beveled needle point, the tail end of the needle point anti-falling sleeve is a 15-30-degree beveled barb, the length of the needle point anti-falling sleeve is 1-2mm, the outer diameter of the needle point anti-falling sleeve is 0.8-2mm, the inner diameter of the needle point anti-falling sleeve is 0.4-1.5mm, the needle point anti-falling sleeve is made of medical stainless steel, the tip anti-falling sleeve is sharp at the tip and the edge of the beveled needle point of the needle point anti-falling sleeve according to the using scene, namely the size of an animal heart and the thickness of a ventricular wall, so that the needle is beneficial to easily puncturing tissues, the beveled barb of the needle point anti-falling sleeve is consistent with the cutting angle of the beveled needle point, sharp treatment is not performed, and the barb serves as the barb of the anti-falling heart perfusion needle, and can be fixed on the inner wall of a ventricle without puncturing the tissues.
The distance between the rear positioning ring and the front end of the needle tube body is 3-7mm, the distance between the rear positioning ring and the tail end of the needle point anti-drop sleeve tube is 1-3mm, the rear positioning ring 13 is a metal or plastic circular ring, the outer diameter is 2-4mm, the rear positioning ring is larger than the outer diameter of the needle point anti-drop sleeve tube 11, the inner diameter of the rear positioning ring is consistent with the outer diameter of the needle tube body 12, the rear positioning ring is fixed on the needle tube body 12 and is positioned at the rear end of the needle point anti-drop sleeve tube 12 by 1-3mm (the distance is slightly larger than the wall of the heart chamber according to the wall of the heart chamber inserted into the heart of the animal).
The heart perfusion needle for the animal heart perfusion experiment is characterized in that the needle cylinder connecting base is a standard luer connector, is made of medical plastics or medical stainless steel materials, is similar to a standard syringe needle base, and can be directly connected with a 3.2mm luer connector of a common needle cylinder and a transfusion tube.
To sum up, the heart perfusion needle for the animal heart perfusion experiment adopts the anti-drop heart perfusion needle provided with the needle point anti-drop sleeve, the needle head tube body and the rear positioning ring, can keep fixed position after effectively penetrating into the ventricle, has certain anti-traction capacity and is not easy to drop; the perfusion tube can be flexibly fixed by adopting the fixing seat with the universal tube, so that the falling-off prevention heart perfusion needle is further prevented from falling off in the perfusion process, and the fixation of the falling-off prevention heart perfusion needle is assisted; the automatic and rapid liquid changing perfusion pump is adopted, so that the liquid changing operation in a perfusion experiment is simplified, and the problem of bubbles generated in manual liquid changing operation is solved; the failure rate of the heart perfusion experiment can be greatly reduced, the occupation of the experiment on the personnel time is greatly improved, and the experiment efficiency is greatly improved.
The above description has been made of specific embodiments of the present invention. It is to be understood that the invention is not limited to the particular embodiments described above, and that devices and structures not described in detail are understood to be implemented in a manner common in the art; various changes or modifications may be made by those skilled in the art within the scope of the appended claims without departing from the spirit of the invention.

Claims (9)

1. The utility model provides an animal heart perfusion experiment is with heart perfusion needle, its characterized in that contains anticreep heart perfusion syringe needle, syringe needle body, the cylinder connection base that connects gradually, the cover is equipped with needle point anticreep sleeve pipe on the anticreep heart perfusion syringe needle, the syringe needle body is close one side cover of anticreep heart perfusion syringe needle is equipped with the rear holding ring.
2. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 1, wherein the length of the needle head tube body is 10-100mm, the outer diameter is 0.4-1.5mm, and the outer diameter is consistent with the inner diameter of the needle point anti-drop sleeve.
3. The heart perfusion needle for the animal heart perfusion experiment as recited in claim 2, wherein the needle point anti-slip sleeve has a beveled needle point with a front end of 15 degrees to 30 degrees and a beveled barb with a tail end of 15 degrees to 30 degrees.
4. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 3, wherein the needle point anti-drop sleeve has a length of 1-2mm, an outer diameter of 0.8-2mm and an inner diameter of 0.4-1.5mm.
5. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 4, wherein the distance between the rear positioning ring and the front end of the needle head tube body is 3-7mm, and the distance between the rear positioning ring and the tail end of the needle point anti-drop sleeve is 1-3mm.
6. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 5, wherein the rear positioning ring has an outer diameter of 2-4mm and an inner diameter consistent with the outer diameter of the needle tube body.
7. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 6, wherein the rear positioning ring is a metal or plastic ring.
8. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 7, wherein the needle cylinder connection base is a standard luer connector.
9. The heart perfusion needle for animal heart perfusion experiments as claimed in claim 8, wherein the needle head tube body and the needle tip anti-drop sleeve are both made of medical stainless steel material, and the syringe connection base is made of medical plastic or medical stainless steel material.
CN202222757791.5U 2022-10-19 2022-10-19 Heart perfusion needle for animal heart perfusion experiment Active CN218870575U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222757791.5U CN218870575U (en) 2022-10-19 2022-10-19 Heart perfusion needle for animal heart perfusion experiment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222757791.5U CN218870575U (en) 2022-10-19 2022-10-19 Heart perfusion needle for animal heart perfusion experiment

Publications (1)

Publication Number Publication Date
CN218870575U true CN218870575U (en) 2023-04-18

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Application Number Title Priority Date Filing Date
CN202222757791.5U Active CN218870575U (en) 2022-10-19 2022-10-19 Heart perfusion needle for animal heart perfusion experiment

Country Status (1)

Country Link
CN (1) CN218870575U (en)

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