CN218860755U - Embryo culture viewing device - Google Patents
Embryo culture viewing device Download PDFInfo
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- CN218860755U CN218860755U CN202222349154.4U CN202222349154U CN218860755U CN 218860755 U CN218860755 U CN 218860755U CN 202222349154 U CN202222349154 U CN 202222349154U CN 218860755 U CN218860755 U CN 218860755U
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
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Abstract
The utility model relates to a cultivate and observe technical field, disclose an embryo culture viewing device, embryo culture viewing device includes casing, culture box body, cultivates carousel, rotation module, micro-imaging module and humidification module, the utility model discloses set up and cultivate carousel and removal module, drive the culture dish through rotation carousel and rotate observation window position, image through micro-imaging module to configuration humidification module, humidification module can provide the wet-type culture for culture box body for whole device possesses the condition of dry-type wet-type culture, satisfies different cultivation demands.
Description
Technical Field
The utility model relates to a cultivate and observe technical field, especially relate to an embryo culture viewing device.
Background
In the field of assisted reproduction technology, selection of the embryo with the best activity for implantation requires in vitro culture and observation of the embryo, which is a necessary task for clinical microscopy and is extremely difficult for the operator. In order to realize in-vitro observation of embryos in the technical field of assisted reproduction, a culture environment which can provide temperature, humidity and gas concentration required by embryo culture is required, microscopic observation imaging is carried out on the embryos under the condition of not damaging the culture environment of the embryos, and unnecessary damage to the embryos caused by the change of the culture environment caused by the microscopic observation operation of the embryos is avoided.
At present, in the field of assisted reproduction, embryos are cultured in vitro through a large box-type culture device or a desktop culture device, the culture device can provide good temperature and gas environment for embryo in vitro culture, but an operator needs to carry out microscopic observation on the embryos like a doctor, and during the microscopic observation of the embryos, the operator needs to transfer the embryos in the culture device to the bottom of a microscope to observe and judge the development condition of the embryos. In the microscopic observation operation, the embryo culture observation device can only realize dry culture or wet culture, and cannot meet various requirements of customers, and if two culture modes are needed, two devices need to be purchased, so that the cost is high.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing an embryo culture viewing device can support dry culture, also can carry out wet culture's embryo culture viewing device.
In order to solve the technical problem, the utility model provides an embryo culture viewing device, include:
a housing having a viewing chamber therein;
the culture box body is arranged in the observation cavity and is provided with an observation window;
the culture rotating disc is rotatably arranged in the culture box body, and a plurality of culture dishes corresponding to the observation windows are arranged on the culture rotating disc along the circumferential direction of the culture rotating disc;
the rotating module is arranged in the observation chamber, is connected with the culture turntable and is used for driving the culture turntable to rotate;
the microscopic imaging module is arranged in the observation chamber and is used for imaging the culture sample in the culture box body through the observation window;
the humidification module is installed in the observation chamber and communicated with the culture box body.
According to the utility model discloses an embryo culture viewing device has following beneficial effect at least:
the culture box is provided with a culture box body and a rotating module, and the rotating module drives a rotating turntable in the culture box body to rotate so that an embryo sample on the rotating turntable is transferred to an observation window for observation by a microscopic imaging module, wherein the initial culture state of the culture box body is dry culture, and the air humidity in the culture box body is low so as to meet the requirement of the dry culture; when wet culture is needed, the humidification module humidifies the gas introduced into the culture box body, so that the humidity in the culture box body is improved, and the wet culture of embryos is further met; the utility model discloses a cultivate viewing device can two kinds of cultivation methods, has practiced thrift the cost.
According to some embodiments of the present invention, the culture dish includes a container body, the container body is provided with an operation cavity with an upward opening, a culture groove with an upward opening is arranged in the operation cavity, the culture groove includes a groove bottom surface and a drainage inclined surface, the lower end of the drainage inclined surface is connected with the groove bottom surface, the upper end of the drainage inclined surface extends obliquely towards the outside direction of the culture groove, the groove bottom surface is provided with at least two culture micro-cavities with upward openings, a culture channel is arranged between the culture micro-cavities, and the culture micro-cavities are communicated with the culture groove;
an injection groove and an injection channel are arranged in the operation cavity, one end of the injection channel is communicated with the culture micro-cavity through the culture groove, and a connecting port of the injection channel connected with the culture groove is equal to or larger than a connecting port of the injection channel connected with the injection groove.
According to some embodiments of the present invention, the bottom surface of the culture box body is provided with a connecting hole, and the rotating module is connected with the culture turntable through the connecting hole; the top surface of the culture box body is provided with a bin opening for the culture dish to pass through.
According to some embodiments of the utility model, the casing be provided with the door of opening that the door corresponds.
According to some embodiments of the utility model, the rotation module is rotating electrical machines and rotatory piece, the rotating electrical machines install in observe the chamber wall of cavity, the pivot of rotating electrical machines with rotatory piece is connected, rotatory piece with cultivate the centre of a circle regional connection of carousel.
According to some embodiments of the invention, the microscopic imaging module comprises:
a mounting bracket mounted to the moving module;
the collecting lens module is mounted at one end of the mounting bracket;
the light source module is connected with the condenser lens module;
the objective lens module is arranged at the other end of the mounting bracket;
the tube mirror module is arranged at the other end of the mounting bracket;
the focusing module is connected with the objective lens module;
the condenser lens module, the observation window, the objective lens module and the tube lens module are sequentially arranged from top to bottom along the same vertical line.
According to some embodiments of the utility model, still include the mobile module, the mobile module install in observe the cavity, micro-imaging module install in the mobile module, the mobile module is used for driving micro-imaging module removes.
According to some embodiments of the invention, the mobile module comprises:
the mobile motor is arranged on the wall of the observation cavity;
the linear module is arranged on the wall of the observation chamber and is connected with the mobile motor;
and the moving sliding block is arranged on the linear module, and the microscopic imaging module is arranged on the moving sliding block.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by the practice of the invention.
Drawings
FIG. 1 is a schematic structural diagram of an embryo culture observation device provided by an embodiment of the present invention;
FIG. 2 is a schematic diagram of the internal structure of an embryo culture observation device provided by an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a microscopic imaging module provided in an embodiment of the present invention;
FIG. 4 is a schematic view of a structure of a culture turntable according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of a back structure of an embryo culture observation device according to an embodiment of the present invention;
reference numerals are as follows:
1. a housing; 1a, a main interactive window; 1b, an instrument state detection window; 1c, an instrument status indicator light; 1d, a bin gate opening button; 1e, a forced opening button of the bin gate; 1f, a chamber gas concentration monitoring port; 1g, opening a bin gate; 1h, a first replacement bin gate; 1i, a second replacement bin gate; 2. a culture box body; 2a, an observation window; 2b, a bin opening; 3. a culture turntable; 4. a rotation module; 5. a microscopic imaging module; 5a, mounting a bracket; 5b, a condenser module; 5c, a light source module; 5d, an objective lens module; 5e, a tube mirror module; 5f, a focusing module; 6. a moving module; 66. a humidifying module; 8. a secondary expansion module; 8a, an air path interface; 8b, a communication interface; 8c and a data interface.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In the description of the present application, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, merely for convenience of description and simplicity of description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be construed as limiting the present application.
In the description of the present application, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood in a specific case by those of ordinary skill in the art.
The embryo culture observation device of the present invention, which is suitable for cell culture, particularly for embryo culture, is described with reference to fig. 1 to 5.
Referring to fig. 1 and 2, an embryo culture observation device according to a preferred embodiment of the present invention includes a housing 1, a culture box body 2, a culture turntable 3, a rotation module 4, a micro-imaging module 5 and a humidification module, wherein the housing 1 has an observation chamber therein; the culture box body 2 is arranged in the observation cavity, and the culture box body 2 is provided with an observation window 2a; the culture rotating disc 3 is rotatably arranged in the culture box body 2, and a plurality of culture dishes corresponding to the observation windows 2a are arranged on the culture rotating disc 3 along the circumferential direction; the rotating module 4 is arranged in the observation chamber, and the rotating module 4 is connected with the culture turntable 3 and used for driving the culture turntable 3 to rotate; the microscopic imaging module 5 is arranged in the observation chamber, and the microscopic imaging module 5 is used for imaging the culture sample in the culture box body 2 through the observation window 2a; the humidification module is installed in observing the cavity, humidification module with cultivate the box body intercommunication.
It should be noted that the culture box body is provided with an air inlet and an air outlet communicated with the interior of the culture box body.
The utility model discloses embryo culture viewing device that preferred embodiment provided sets up cultivates carousel 3 and moving module 6, drives the culture dish through rotatory carousel and rotates observation window 2a position, images through microscopic imaging module 5.
Referring to fig. 2, the embryo culture observation device according to the preferred embodiment of the present invention further includes a humidification module 66, and the humidification module 66 includes a humidification bottle and a heating and heat preservation module which are connected in sequence; the casing 1 is provided with a first replacement bin gate 1h corresponding to the humidification bottle.
Specifically, when wet culture is to be realized, an internal air path system does not need to be modified, and the humidification module is connected to the air inlet of the culture box body 2, so that wet culture can be realized. The humidifying bottle of the humidifying module can be replaced through the first replacement bin gate 1h.
The utility model discloses a humidification module also can set up to improve culture apparatus internal environment humidity through the evaporation of water in the humidification basin at the inside humidification basin that increases of culture apparatus.
Referring to fig. 5, the embryo culture observation device according to the preferred embodiment of the present invention further includes an auxiliary expansion module 8 disposed at the back of the embryo culture observation device and composed of a gas path interface 8a, a communication interface 8b and a data interface 8 c. The air path interface 8a is positioned at the back, and the air path interface 8a comprises an auxiliary module air inlet and an auxiliary module air outlet which are respectively connected with the air path system, is connected with the auxiliary module through a pipeline and can supply air for the external auxiliary module. And communication data exchange between the main module and the auxiliary module is realized for the communication interface 8 b. The data interface 8c can transmit data information acquired by the camera of the secondary module to the upper computer system of the primary module, so as to acquire and store image data of the secondary module.
In some embodiments of the utility model, the bottom surface of the culture box body 2 is provided with a connecting hole, and the rotating module 4 is connected with the culture turntable 3 through the connecting hole; the top surface of the culture box body 2 is provided with a bin opening 2b for the culture dish to pass through. Specifically, the hatch 2b may be opened directly, and then the culture dish may be placed in the culture container body 2.
In some embodiments of the present invention, the housing 1 is provided with an opening door 1g corresponding to the door opening 2b. The opening bin door 1g corresponds to the bin opening 2b, and the bin opening 2b can be opened by directly opening the opening bin door 1g.
The utility model discloses an in some embodiments, rotation module 4 is rotating electrical machines and rotatory piece, and the rotating electrical machines is installed in the chamber wall of observing the cavity, and the pivot and the rotatory piece of rotating electrical machines are connected, and rotatory piece is connected with the centre of a circle region of cultivateing carousel 3.
In some embodiments of the present invention, the microscopic imaging module 5 includes a mounting bracket 5a, a condenser module 5b, a light source module 5c, an objective lens module 5d, a tube lens module 5e, and a focusing module 5f, and the mounting bracket 5a is mounted on the moving module 6; the condenser module 5b is mounted at one end of the mounting bracket 5 a; the light source module 5c is connected with the condenser module 5 b; the objective lens module 5d is mounted at the other end of the mounting bracket 5 a; the tube mirror module 5e is arranged at the other end of the mounting bracket 5 a; the focusing module 5f is connected with the objective lens module 5 d; wherein, condenser module 5b, observation window 2a, objective module 5d and tube lens module 5e set gradually along same vertical line top-down.
According to some embodiments of the utility model, still include the mobile module, the mobile module install in observe the cavity, micro-imaging module install in the mobile module, the mobile module is used for driving micro-imaging module removes.
It is specific, set up the cultivation carousel and with the removal module, drive the culture dish through rotatory carousel and rotate the observation window position, form images through micro-imaging module, simultaneously because the possible position of culture dish does not align completely with observation window's central point, can drive micro-imaging module through the removal module and remove, make micro-imaging module align with the culture dish, consequently, the cultivation carousel only need rotate once at every turn, will need look over the culture dish and shift to observation window department, the rotational frequency of cultivation carousel has been reduced, and then reduce the vibrations to the embryo.
In some embodiments of the present invention, the moving module 6 includes a moving motor, a linear module and a moving slider, and the moving motor is installed on the cavity wall of the observation cavity; the linear module is arranged on the wall of the observation cavity and is connected with the mobile motor; the movable sliding block is arranged on the linear module, and the microscopic imaging module 5 is arranged on the movable sliding block.
It should be noted that the linear module is a linear moving module in the market, and the description thereof is omitted here.
The utility model discloses an in some embodiments, casing 1 still is provided with main mutual window 1a, instrument state detection window 1b, instrument state pilot lamp 1c, door open button 1d, door force open button 1e and the gaseous concentration monitoring mouth of bin 1f respectively.
The utility model discloses in the example, casing 1 is provided with the second that is used for changing the filter and changes door 1i, when the filter need be changed, can directly open the second and change door 1i and change.
In addition, the main interactive window adopts a touch screen scheme, so that a user can realize the operations of setting instrument parameters, adding and taking out culture dishes, looking up image information in the embryo culture process and the like through the main interactive window, and the related required operations in the embryo culture process of the user are met.
Furthermore, the instrument state detection window is used for displaying the information of the concentration, the temperature and the humidity of the real-time gas in the current culture device, so that a user can conveniently and visually monitor the real-time data information in the culture device.
Furthermore, the instrument state indicator is used for indicating instrument state information, and the state information of the current instrument of the user is prompted through different colors and flashing states, for example, the green breathing lamp indicates that the instrument is in a normal working state at present, and red light indicates that alarm information exists in the current instrument.
Furthermore, the bin gate opening button is used for opening the bin gate in a normal state, when the instrument state indicating lamp is in a normally green state, the bin gate is opened after the bin gate opening button is pressed down, and the bin gate is in an invalid state after the bin gate opening button is pressed down in other time.
Further, the door forced opening button is used for forcibly opening the door in an emergency state, for example, the door forced opening button cannot be used for opening the door when an instrument fails or the instrument is powered off and cannot be used for related operations.
The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and substitutions can be made without departing from the technical principle of the present invention, and these modifications and substitutions should also be regarded as the protection scope of the present invention.
Claims (8)
1. An embryo culture viewing device, comprising:
a housing having a viewing chamber therein;
the culture box body is arranged in the observation cavity and is provided with an observation window;
the culture rotating disc is rotatably arranged inside the culture box body and is provided with a plurality of culture dish positions corresponding to the observation windows along the circumferential direction;
the rotating module is arranged in the observation chamber, is connected with the culture turntable and is used for driving the culture turntable to rotate;
the microscopic imaging module is arranged in the observation chamber and is used for imaging the culture sample in the culture box body through the observation window;
the humidification module is arranged in the observation chamber and communicated with the culture box body.
2. The embryo culture observation apparatus of claim 1, wherein: the bottom surface of the culture box body is provided with a connecting hole, and the rotating module is connected with the culture turntable through the connecting hole; the top surface of the culture box body is provided with a bin opening for the culture dish to pass through.
3. The embryo culture observing apparatus according to claim 2, wherein: the shell is provided with an opening bin door corresponding to the bin opening.
4. The embryo culture observing apparatus according to claim 1, wherein: the rotating module comprises a rotating motor and a rotating block, the rotating motor is installed on the wall of the observation chamber, a rotating shaft of the rotating motor is connected with the rotating block, and the rotating block is connected with the circle center area of the culture turntable.
5. The embryo culture observing apparatus according to claim 1, wherein: the microscope imaging device is characterized by further comprising a moving module, wherein the moving module is installed in the observation cavity, the microscope imaging module is installed in the moving module, and the moving module is used for driving the microscope imaging module to move.
6. The embryo culture observing apparatus according to claim 5, wherein: the microscopic imaging module includes:
a mounting bracket mounted to the mobile module;
the collecting lens module is mounted at one end of the mounting bracket;
the light source module is connected with the condenser lens module;
the objective lens module is arranged at the other end of the mounting bracket;
the tube mirror module is arranged at the other end of the mounting bracket;
the focusing module is connected with the objective lens module;
the condenser lens module, the observation window, the objective lens module and the tube lens module are sequentially arranged from top to bottom along the same vertical line.
7. The embryo culture observation apparatus of claim 6, wherein: the moving module includes:
the mobile motor is arranged on the wall of the observation cavity;
the linear module is arranged on the wall of the observation chamber and is connected with the mobile motor;
and the moving sliding block is arranged on the linear module, and the microscopic imaging module is arranged on the moving sliding block.
8. The embryo culture observing apparatus according to claim 1, wherein: the shell is provided with a main interaction window, an instrument state detection window, an instrument state indicator lamp, a bin gate opening button, a bin gate forced opening button and a bin gas concentration monitoring port.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222349154.4U CN218860755U (en) | 2022-09-02 | 2022-09-02 | Embryo culture viewing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222349154.4U CN218860755U (en) | 2022-09-02 | 2022-09-02 | Embryo culture viewing device |
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| CN218860755U true CN218860755U (en) | 2023-04-14 |
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| CN202222349154.4U Active CN218860755U (en) | 2022-09-02 | 2022-09-02 | Embryo culture viewing device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024046258A1 (en) * | 2022-09-02 | 2024-03-07 | 广州市华粤行医疗科技有限公司 | Medium culture observation apparatus and gas path control method therefor |
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2022
- 2022-09-02 CN CN202222349154.4U patent/CN218860755U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024046258A1 (en) * | 2022-09-02 | 2024-03-07 | 广州市华粤行医疗科技有限公司 | Medium culture observation apparatus and gas path control method therefor |
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