CN218725874U - Nuclear type analysis dropping piece device - Google Patents

Nuclear type analysis dropping piece device Download PDF

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Publication number
CN218725874U
CN218725874U CN202223420893.4U CN202223420893U CN218725874U CN 218725874 U CN218725874 U CN 218725874U CN 202223420893 U CN202223420893 U CN 202223420893U CN 218725874 U CN218725874 U CN 218725874U
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Prior art keywords
dyeing
rack
wall
pipeline
glass slide
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CN202223420893.4U
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Chinese (zh)
Inventor
刘明录
张传鹏
强邦明
金海锋
冯建海
韩庆梅
许淼
李希鹏
李颖
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Shandong Research Institute Of Adult Cell Industry Technology Co ltd
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Shandong Research Institute Of Adult Cell Industry Technology Co ltd
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Abstract

The utility model discloses a karyotype analysis dropping device belongs to chromosome karyotype analysis technical field. Including washing dyeing platform, wash dyeing platform includes base and backup pad, and the upper portion of base is equipped with dyeing box, and the backup pad is vertical to be set up on dyeing box's a lateral wall, and one side inner wall that the backup pad was kept away from to dyeing box rotates and is equipped with the rack column spinner, and the outer wall of rack column spinner is equipped with the draw-in groove, and the joint has the slide glass rack in the draw-in groove, and one side inner wall that dyeing box and rack column spinner are relative is equipped with a plurality of evenly distributed's prism, and the one end of slide glass rack sets up on the prism. The utility model can simultaneously dye a plurality of slides; the reagent is added and removed directly through the opening and closing of the reagent bottle and the dyeing liquid switch valve, so that the operation time is reduced; by adjusting the inclination of the placing rack, the water flow strength can be adjusted, and the dyeing liquid can be washed away more quickly by inclined washing; the design of the reagent discharge port is beneficial to more uniform flushing and dyeing.

Description

Nuclear type analysis dropping piece device
Technical Field
The utility model relates to a karyotype analysis dropping device belongs to chromosome karyotype analysis technical field.
Background
The karyotype analysis is to take metaphase chromosomes as research objects, analyze, compare, sort and number the chromosomes by means of a banding technology according to the characteristics of the length, the position of a centromere, the proportion of long and short arms, the existence of satellite and the like of the chromosomes, and diagnose according to the variation condition of the chromosome structure and the number. Karyotyping can provide important basis for the study of cell genetic classification, genetic relationship between species, and chromosome number and structural variation.
The staining solution for karyotype analysis is mainly Giemsa staining solution which is most suitable for staining blood smear specimens, blood cells, plasmodium, rickettsia, bone marrow cells, spinal cord cells and the like. The chromosome is treated with protease, etc. before dyeing, and then dyed with Giemsa dye liquor, and the chromosome can be colored in a striation shape with different shades. Giemsa stain can stain the cell nucleus into purple red or blue purple, the cytoplasm into pink, and clear cell and chromosome images are shown under a light microscope.
Biological scientific research institutions need to make dyeing and wash slide glass samples in large quantities when carrying out chromosome karyotype analysis, but lack the equipment that can carry out a plurality of slide staining simultaneously in the market, and still have the dyeing operation process complicacy, operating time is long, wash with the dyeing inefficiency, wash with the poor problem of dyeing effect.
In view of the above, the prior art is obviously inconvenient and disadvantageous in practical use, and needs to be improved.
Disclosure of Invention
The to-be-solved technical problem of the utility model is to above not enough, provide one kind can be simultaneously to a plurality of slide staining, operating time weak point, wash and dye fast and wash with the effectual karyotype analysis of dyeing drip piece device.
An optimized scheme is that a nuclear type analysis dripping device comprises a washing and dyeing table, wherein the washing and dyeing table comprises a base and a supporting plate, a dyeing box is arranged at the upper part of the base, the supporting plate is vertically arranged on one side wall of the dyeing box, a plurality of uniformly distributed reagent bottles are arranged on the inner wall of the upper part of the supporting plate, a pipeline A is arranged at the bottom of each reagent bottle, a valve is arranged on each pipeline, the pipeline A is arranged in parallel through a pipeline B, and a spray head is communicated with the middle pipeline of the pipeline B;
the inner wall of one side of the dyeing box, which is far away from the supporting plate, is rotatably provided with a rotary column for placing a rack, the outer wall of the rotary column for placing the rack is provided with a clamping groove, and a slide placing rack is clamped in the clamping groove;
the inner wall of one side of the staining box opposite to the rotating column of the placing rack is provided with a plurality of prisms which are evenly distributed, and one end of the glass slide placing rack is arranged on the prisms.
Furthermore, the head of the glass slide placing frame is sleeved with a telescopic sleeve, the side wall opposite to the telescopic sleeve is provided with a groove, the head of the glass slide placing frame is provided with a convex block, and the convex block is arranged in the groove.
Furthermore, slide glass rack be equipped with a plurality of evenly distributed's rectangular hole, the length direction lateral wall of rectangular hole is equipped with the blend stop, the width direction bottom inner wall symmetry of rectangular hole is equipped with and blocks the piece.
Furthermore, the mouth of the spray head is arranged obliquely, and the oblique direction of the mouth of the spray head faces the glass slide placing rack.
Further, dyeing box's lateral wall bottom be equipped with the drain pipe, the inner chamber intercommunication setting of drain pipe and dyeing box, the head of drain pipe is equipped with the rubber buffer.
Furthermore, the upper surface of the telescopic sleeve is provided with an operating button.
The utility model adopts the above technical scheme after, compare with prior art, have following advantage:
1. the staining of a plurality of slides can be carried out simultaneously;
2. the reagent is added and removed directly through the opening and closing of the reagent bottle and the dyeing liquid switch valve, so that the operation time is reduced;
3. by adjusting the inclination of the placing rack, the water flow strength can be adjusted, and the dyeing liquid can be washed away more quickly by inclined washing; 4. the design of the reagent discharge port is beneficial to more uniform flushing and dyeing.
Drawings
FIG. 1 is a schematic structural diagram of a nuclear-type analysis droplet plate device of the present invention;
FIG. 2 is a schematic structural view of a washing and dyeing station of the nuclear type analysis dripping device of the present invention;
FIG. 3 is a schematic structural view of a rotary column of a rack of the nuclear type analysis plate dropping device of the present invention;
FIG. 4 is a schematic structural view of a slide holder of the nuclear-type slide analyzer of the present invention;
FIG. 5 is an enlarged schematic view of portion A of FIG. 4;
in the figure, 1-washing dyeing table, 2-base, 3-support plate, 4-dyeing box, 5-reagent bottle, 6-pipeline A, 7-valve, 8-pipeline B, 9-spray head, 10-rack rotating column, 11-clamping groove, 12-glass slide rack, 13-prism, 14-telescopic sleeve, 15-lug, 16-rectangular hole, 17-stop strip, 18-stop block, 19-liquid outlet pipe, 20-rubber plug and 21-operating button.
Detailed Description
In order to clearly understand the technical features, objects, and effects of the present invention, embodiments of the present invention will be described with reference to the accompanying drawings.
The embodiment is as shown in fig. 1, 2, 3, 4 and 5, the utility model provides a nuclear type analysis dropping piece device, which comprises a washing and dyeing table 1, wherein the washing and dyeing table 1 comprises a base 2 and a supporting plate 3, the upper part of the base 2 is provided with a dyeing box 4, the supporting plate 3 is vertically arranged on one side wall of the dyeing box 4, the inner wall of the upper part of the supporting plate 3 is provided with a plurality of uniformly distributed reagent bottles 5, the bottom of each reagent bottle 5 is provided with a pipeline A6, the pipeline is provided with a valve 7, the pipeline A6 is arranged in parallel through a pipeline B8, and the middle pipeline of the pipeline B8 is communicated with a spray head 9;
the inner wall of one side of the dyeing box 4, which is far away from the support plate 3, is rotatably provided with a rack rotating column 10, the outer wall of the rack rotating column 10 is provided with a clamping groove 11, and a glass slide rack 12 is clamped in the clamping groove 11;
the inner wall of one side of the staining box 4 opposite to the rack rotating column 10 is provided with a plurality of prisms 13 which are evenly distributed, and one end of the glass slide rack 12 is arranged on the prism 13.
The head of the glass slide placing frame 12 is sleeved with a telescopic sleeve 14, the side wall opposite to the telescopic sleeve 14 is provided with a groove, the head of the glass slide placing frame 12 is provided with a convex block 15, and the convex block 15 is arranged in the groove.
The glass slide placing rack 12 is provided with a plurality of uniformly distributed rectangular holes 16, the side walls of the rectangular holes 16 in the length direction are provided with barrier strips 17, and the inner walls of the bottoms of the rectangular holes 16 in the width direction are symmetrically provided with stop blocks 18.
The mouth of the nozzle 9 is inclined, and the inclined direction of the mouth of the nozzle 9 faces the glass slide placing rack 12.
Dyeing box 4's lateral wall bottom be equipped with drain pipe 19, the inner chamber intercommunication setting of drain pipe 19 and dyeing box 4, the head of drain pipe 19 is equipped with rubber buffer 20.
The upper surface of the telescopic sleeve 14 is provided with an operating button 21.
The utility model discloses a theory of operation:
placing the glass slide in the rectangular hole 16, wherein the position of the glass slide can be fixed and limited by the barrier strip 17 and the barrier block 18, then placing one end of the glass slide placing rack 12 in the clamping groove 11 of the placing rack rotary column 10, extending the length of the glass slide placing rack 12 by the telescopic sleeve 14 in a telescopic way, then placing the telescopic sleeve 14 on the prism 13, and controlling the angle of the glass slide placing rack 12 in this way; so as to control the washing and dyeing effect,
then adjust the reagent quantity of different reagent bottles 5 respectively through valve 7 of reagent bottle 5, then the reagent evenly sprays on the slide through shower nozzle 9, adjusts simultaneously flexible cover 14 in prismatic 13 position, makes things convenient for the slide to dip the degree of depth of dyeing box 4, is convenient for dye, then opens drain pipe 19's rubber buffer 20, and the drain pipe 19 discharge of reagent through dyeing box 4.
The foregoing is illustrative of the best mode of the invention, and details not described herein are within the common general knowledge of a person of ordinary skill in the art. The protection scope of the present invention is subject to the content of the claims, and any equivalent transformation based on the technical teaching of the present invention is also within the protection scope of the present invention.

Claims (6)

1. The karyotype analysis dripping device is characterized in that: the washing and dyeing device comprises a washing and dyeing table (1), wherein the washing and dyeing table (1) comprises a base (2) and a supporting plate (3), a dyeing box (4) is arranged on the upper part of the base (2), the supporting plate (3) is vertically arranged on one side wall of the dyeing box (4), a plurality of uniformly distributed reagent bottles (5) are arranged on the inner wall of the upper part of the supporting plate (3), a pipeline A (6) is arranged at the bottom of each reagent bottle (5), a valve (7) is arranged on each pipeline, the pipeline A (6) is arranged in parallel through a pipeline B (8), and a spray head (9) is communicated with the middle pipeline of the pipeline B (8);
a rack rotating column (10) is rotatably arranged on the inner wall of one side, away from the supporting plate (3), of the dyeing box (4), a clamping groove (11) is formed in the outer wall of the rack rotating column (10), and a glass slide rack (12) is clamped in the clamping groove (11);
a plurality of prisms (13) which are uniformly distributed are arranged on the inner wall of one side of the staining box (4) opposite to the rotary column (10) of the placing rack, and one end of the glass slide placing rack (12) is arranged on the prisms (13).
2. The karyotyping slide device according to claim 1, wherein: the head of the glass slide placing frame (12) is sleeved with a telescopic sleeve (14), the opposite side wall of the telescopic sleeve (14) is provided with a groove, the head of the glass slide placing frame (12) is provided with a convex block (15), and the convex block (15) is arranged in the groove.
3. The karyotyping slide device according to claim 1, wherein: the glass slide placing rack (12) is provided with a plurality of uniformly distributed rectangular holes (16), the side walls of the rectangular holes (16) in the length direction are provided with barrier strips (17), and the inner walls of the rectangular holes (16) in the bottom in the width direction are symmetrically provided with stop blocks (18).
4. The karyotyping slide device according to claim 1, wherein: the mouth of the spray head (9) is obliquely arranged, and the mouth of the spray head (9) is obliquely oriented to the glass slide placing rack (12).
5. The karyotyping slide device according to claim 1, wherein: the lateral wall bottom of dyeing box (4) be equipped with drain pipe (19), the inner chamber intercommunication setting of drain pipe (19) and dyeing box (4), the head of drain pipe (19) is equipped with rubber buffer (20).
6. The karyotyping titration device according to claim 2, wherein: the upper surface of the telescopic sleeve (14) is provided with an operating button (21).
CN202223420893.4U 2022-12-21 2022-12-21 Nuclear type analysis dropping piece device Active CN218725874U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223420893.4U CN218725874U (en) 2022-12-21 2022-12-21 Nuclear type analysis dropping piece device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223420893.4U CN218725874U (en) 2022-12-21 2022-12-21 Nuclear type analysis dropping piece device

Publications (1)

Publication Number Publication Date
CN218725874U true CN218725874U (en) 2023-03-24

Family

ID=85626058

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223420893.4U Active CN218725874U (en) 2022-12-21 2022-12-21 Nuclear type analysis dropping piece device

Country Status (1)

Country Link
CN (1) CN218725874U (en)

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