CN218521257U - PCR automatic sampling system - Google Patents

Abstract

The utility model provides a PCR automatic sampling system, which comprises a bearing unit, wherein the bearing unit is provided with a bearing position for bearing a sample container; further comprising: the conveying device comprises a first driving unit, a first bracket and a conveying belt, wherein the first driving unit is used for driving the conveying belt to move circularly on the first bracket; a plurality of bearing units are dispersedly arranged on the conveyor belt; the position sensor is used for detecting whether the sample container on the bearing unit reaches a sampling position; the fixing device is used for fixing the sample container moved to the sampling position; the opening and closing cover device is arranged on the upper side of the sampling position and is used for opening and closing the cover of the sample container. The utility model has the advantages of automation, high sampling efficiency and the like.

Description

PCR automatic sampling system

Technical Field

The utility model relates to a PCR detects, in particular to automatic sampling system of PCR.

Background

At present, in the control of the new coronavirus epidemic situation, the detection amount of nucleic acid samples is huge, and the operation of each tube of samples is as follows: the inspector unscrews the cover, then uses the pipette to take a sample and add the sample to the lysate, finally covers the cover and screws, and the same operation is carried out for the next sample. To avoid cross contamination between samples (positive samples), only one tube of sample can be opened at a time, and after the sample is taken and the cover is closed, the next sample is opened. This mode of operation has several disadvantages, such as:

1. the sampling efficiency is low, each sample needs to be opened and closed manually, the working efficiency is low, and the requirement of mass detection cannot be met;

2. the security is poor, because need artifical intervention, inevitably brings the pollution of uncapping in-process.

SUMMERY OF THE UTILITY MODEL

For solving the not enough among the above-mentioned prior art scheme, the utility model provides an automatic sampling system of PCR.

The utility model aims at realizing through the following technical scheme:

the PCR automatic sampling system comprises a bearing unit, wherein the bearing unit is provided with a bearing position for bearing a sample container; the PCR automated sampling system further comprises:

the conveying device comprises a first driving unit, a first bracket and a conveying belt, wherein the first driving unit is used for driving the conveying belt to move circularly on the first bracket; a plurality of bearing units are dispersedly arranged on the conveyor belt;

a position sensor for detecting whether a sample container on the carrying unit reaches a sampling position;

a fixing device for fixing the sample container moved to the sampling position;

and the opening and closing cover device is arranged on the upper side of the sampling position and is used for opening and closing the cover of the sample container.

Compared with the prior art, the utility model discloses the beneficial effect who has does:

1. the sampling efficiency is high;

the sample container moves to a sampling position along with the conveyor belt, and the steps of fixing, opening and closing the cover are all carried out automatically without manual intervention, so that the sampling efficiency is obviously improved;

the fixing device and the cover opening and closing device are specifically designed, so that the sample container at the sampling position can be accurately fixed, the cover opening and closing are utilized to realize the sampling function, and the sampling efficiency is further improved;

2. the safety is good;

in the automatic sampling process, manual intervention is not needed, cross contamination is avoided, and safety is improved.

Drawings

The disclosure of the present invention will become more readily understood with reference to the accompanying drawings. As is readily understood by those skilled in the art: these drawings are only intended to illustrate the technical solution of the present invention and are not intended to limit the scope of the present invention. In the figure:

fig. 1 is a schematic structural diagram of an automatic sampling system for PCR according to an embodiment of the present invention.

Detailed Description

Fig. 1 and the following description depict alternative embodiments of the invention to teach those skilled in the art how to make and reproduce the invention. For explaining the technical solution of the present invention, some conventional aspects have been simplified or omitted. Those skilled in the art will appreciate variations or substitutions from these embodiments that will be within the scope of the invention. Those skilled in the art will appreciate that the features described below can be combined in various ways to form multiple variations of the invention. Accordingly, the present invention is not limited to the following alternative embodiments, but is only limited by the claims and their equivalents.

Example 1:

fig. 1 schematically shows a schematic structural diagram of a PCR automated sampling system according to an embodiment of the present invention, and as shown in fig. 1, the PCR automated sampling system includes:

the carrying unit 11 is provided with carrying positions for carrying the sample containers, for example, one carrying position is arranged on each carrying unit 11;

the conveying device comprises a first driving unit, a first bracket and a conveying belt 21, wherein the first driving unit is used for driving the conveying belt 21 to move circularly on the first bracket; a plurality of carrying units 11 are dispersedly disposed on the conveyor belt 21; the transmission device is the prior art, and the specific structure and the working mode are not described again;

a position sensor for detecting whether a sample container on the carrying unit 11 reaches a sampling position;

a fixing device for fixing the sample container moved to the sampling position;

and the cover opening and closing device is arranged on the upper side of the sampling position and is used for opening and closing the cover of the sample container.

In order to automatically control the movement of the conveyor belt 21 (carrying unit 11), further, the PCR automated sampling system further comprises:

and the controller controls whether to close the first driving unit according to the signal of the position sensor, and if the position sensor detects the bearing unit 11, the controller controls the first driving unit to stop working, so that the bearing unit 11 is accurately positioned at the sampling position.

In order to automatically fix the sample container at the sampling position against rotation, further, the fixing device comprises:

the first moving unit and the first clamping unit are driven by the first moving unit to move to and retreat from the sampling position, and the first clamping unit is used for fixing the sample container.

In order to improve the working reliability, further, the first moving unit adopts a rotary operation structure and comprises a motor and a rotary arm driven by the motor, and the first clamping unit is arranged on the rotary arm; alternatively, the first and second electrodes may be,

the first moving unit adopts a linear operation structure and comprises a first cylinder, a first telescopic arm and a first guide unit, wherein the first cylinder drives the first telescopic arm, the first guide unit drives the first cylinder, the first clamping unit is arranged on the first telescopic arm, and the first telescopic arm moves linearly along the first guide unit.

In order to reduce the structural complexity, further, the switch cover device comprises:

the second driving unit is used for driving the second clamping unit to rotate;

a second clamping unit for fixing a cover of the sample container;

and the second moving unit is used for driving the second clamping to move up and down.

In order to drive the second clamping unit to automatically move up and down in the opening and closing cover, further, the second moving unit includes:

the second cylinder and a second telescopic arm driven by the second cylinder, the second driving unit drives the second cylinder to rotate, and the second clamping unit is fixed on the second telescopic arm.

In order to accurately open and close the cover, further, the opening and closing cover device further includes:

and a second guide unit, such as a guide, through which the second telescopic arm passes, such that the second telescopic arm can only vertically move up and down along the second guide unit.

In order to prevent the cover from being excessively rotated, further, the opening and closing cover device further includes:

a torque detection unit for detecting a rotational torque of the second driving unit.

Example 2:

according to the utility model discloses the application example of PCR automatic sampling system in nucleic acid detection of embodiment 1.

In this application example, as shown in fig. 1, the PCR automated sampling system includes:

each carrying unit 11 has only one carrying position for carrying a sample container;

in the conveying device, a first driving unit adopts a motor, and a plurality of bearing units 11 are arranged on an annular conveying belt 21 at equal intervals;

a position sensor, which uses a photoelectric switch, and is used for detecting whether the sample container on the bearing unit 11 reaches a sampling position;

the controller controls whether to close the first driving unit according to the signal of the position sensor, and when the position sensor detects the bearing unit 11, the controller controls the first driving unit to stop working, so that the bearing unit 11 (sample container) is accurately positioned at a sampling position;

in the fixing device, a first moving unit adopts a linear motion structure, namely comprises a first air cylinder, a first telescopic arm driven by the first air cylinder and a first guide unit, wherein the first guide unit adopts a guide piece, and the first telescopic arm penetrates through a guide hole of the guide piece, so that the first telescopic arm can only linearly move in the horizontal direction; the first clamping unit adopts an electric clamping jaw and is arranged at the end part of the first telescopic arm, and the moving direction of the clamping jaw is vertical to the first telescopic arm; under the drive of a first air cylinder, the first telescopic arm moves linearly along the first guide unit, so that the first clamping unit moves to and exits from the sampling position;

in the cover opening and closing device, a second driving unit, a second moving unit and a second clamping unit are movably arranged from top to bottom and are positioned at the upper side of the sampling position; the second moving unit comprises a second cylinder, a second telescopic arm driven by the second cylinder and a second guide unit, the second guide unit adopts a guide piece, and the second telescopic arm penetrates through a guide hole of the guide piece, so that the second telescopic arm can only linearly move in the vertical direction; the second driving unit adopts a motor to drive the second cylinder and the second telescopic arm to rotate, the second telescopic arm is arranged on the second guide unit, and the second clamping unit adopts an electric clamping jaw and is fixed at the bottom end of the second telescopic arm; the torque detection unit is used for detecting the rotation torque of the second driving unit.

The working mode of the PCR automatic sampling system of this embodiment is:

the position sensor detects in real time, and when the carrying unit 11 reaches the detection position, the controller controls the first driving unit to stop working, so that the carrying unit 11 is accurately positioned at the detection position;

the first cylinder drives the first telescopic arm to linearly extend along the horizontal direction, so that the first clamping unit is positioned at a sampling position, and a sample container is accurately clamped;

the second cylinder drives the second telescopic arm to vertically move downwards along the second guide unit, so that the second clamping unit is positioned at a sampling position and clamps a cover of the sample container, and the cover is fixed on the sample container through threads;

the second driving unit drives the second air cylinder, the second telescopic arm and the second clamping unit to rotate in the forward direction, so that the cover is driven to rotate in the forward direction; meanwhile, the second cylinder drives the second telescopic arm to move upwards, so that the cover is separated from the sample container, and the cover opening is completed;

sampling the sample by using a pipette;

the second cylinder drives the second telescopic arm to move downwards, so that the cover is contacted with the top end of the sample container;

the second driving unit drives the second air cylinder, the second telescopic arm and the second clamping unit to rotate reversely, meanwhile, the second air cylinder drives the second telescopic arm to move downwards continuously, so that the cover is driven to rotate reversely at the top end of the sample container, the torque detection unit detects the rotation torque of the second driving unit, when a set value is reached, the second driving unit stops, and the cover is fixed on the sample container again at the moment, and the cover closing is completed.

It can be seen from this embodiment that the sample is realized along with the removal of conveyer belt 21, the detection of position, the fixed of sample container, uncap and close the lid all is automatic, need not artificial intervention, has improved sample efficiency and security.

Example 3:

according to the utility model discloses embodiment 1's PCR automatic sampling system's application example is different from embodiment 2:

first mobile unit adopts rotatory operation structure, including motor and its driven swinging boom, and first clamping unit adopts electronic clamping jaw, sets up on the first swinging boom, the moving direction of clamping jaw is on a parallel with the axis direction of first flexible arm.

Claims (10)

1. A PCR automated sampling system, comprising a carrying unit having carrying positions for carrying sample containers; characterized in that, the PCR automatic sampling system further comprises:

   the conveying device comprises a first driving unit, a first bracket and a conveying belt, wherein the first driving unit is used for driving the conveying belt to move circularly on the first bracket; a plurality of bearing units are dispersedly arranged on the conveyor belt;

   a position sensor for detecting whether a sample container on the carrier unit reaches a sampling position;

   a fixing device for fixing the sample container moved to the sampling position;

   and the opening and closing cover device is arranged on the upper side of the sampling position and is used for opening and closing the cover of the sample container.
2. 2. The PCR automated sampling system of claim 1, further comprising:

   a controller controlling whether to turn off the first driving unit according to a signal of the position sensor.
3. 3. The PCR automated sampling system of claim 1, wherein the fixture comprises:

   the first moving unit and the first clamping unit are driven by the first moving unit to move to and retreat from the sampling position, and the first clamping unit is used for fixing the sample container.
4. 4. The PCR automated sampling system of claim 3, wherein the first moving unit adopts a rotary operation structure and comprises a motor and a rotary arm driven by the motor, and the first clamping unit is arranged on the rotary arm; alternatively, the first and second electrodes may be,

   the first moving unit adopts a linear operation structure and comprises a first cylinder, a first telescopic arm and a first guide unit, wherein the first cylinder drives the first telescopic arm, the first guide unit drives the first cylinder, the first clamping unit is arranged on the first telescopic arm, and the first telescopic arm moves linearly along the first guide unit.
5. 5. The PCR automated sampling system of claim 1, wherein the switch cover device comprises:

   the second driving unit is used for driving the second clamping unit to rotate;

   a second clamping unit for fixing a cover of the sample container;

   and the second moving unit is used for driving the second clamping to move up and down.
6. 6. The PCR automated sampling system of claim 5, wherein the second mobile unit comprises:

   the second cylinder and a second telescopic arm driven by the second cylinder, the second driving unit drives the second cylinder to rotate, and the second clamping unit is fixed on the second telescopic arm.
7. 7. The PCR automated sampling system of claim 6, wherein the switch cover device further comprises:

   and the second telescopic arm moves up and down along the second guide unit.
8. 8. The PCR automated sampling system of claim 7, wherein the second guide unit has a guide hole allowing the second telescopic arm to pass through.
9. 9. The PCR automated sampling system of claim 5, wherein the switch cover device further comprises:

   a torque detection unit for detecting a rotational torque of the second driving unit.
10. 10. The PCR automated sampling system of claim 5, wherein the first and second drive units employ motors.

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