CN218404215U - Low pressure formula nucleic acid detection device - Google Patents
Low pressure formula nucleic acid detection device Download PDFInfo
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- CN218404215U CN218404215U CN202222578528.XU CN202222578528U CN218404215U CN 218404215 U CN218404215 U CN 218404215U CN 202222578528 U CN202222578528 U CN 202222578528U CN 218404215 U CN218404215 U CN 218404215U
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Abstract
The utility model discloses a low-pressure nucleic acid detecting device, which comprises a piston unit, a first sample storage unit provided with a sample storage groove and a second sample storage unit provided with a sample storage cavity; the amplification reagent and the nucleic acid sample can be placed in the sample storage groove, then the second sample storage unit in which the detection reagent is pre-stored is connected with the first sample storage unit, and due to the arrangement of the piston unit, the first sample storage unit is sealed, so that the amplification reaction between the nucleic acid sample and the amplification reagent is facilitated; after the amplification reaction is finished, moving the piston unit to enable the sample storage groove to be communicated with the sample storage cavity, and mixing the amplified nucleic acid sample with a detection reagent in the sample storage cavity to finish the detection reaction; in the process, the amplified nucleic acid sample and the detection reagent are mixed by changing the position of the piston unit, so that the condition of pressure mutation can be avoided, the peak value of internal pressure is reduced, the pollutants are not easy to seep out from the low-pressure nucleic acid detection device, and the safety is greatly improved.
Description
Technical Field
The utility model relates to a nucleic acid amplification detection area especially relates to a low pressure formula nucleic acid detection device.
Background
The nucleic acid amplification detection refers to a method of performing an amplification reaction on a collected nucleic acid sample and then detecting the amplified sample after the reaction. One of the detection means that is currently used is isothermal amplification technology, which can perform single-molecule nucleic acid detection at a constant and low temperature for only 30 min.
Currently, a mainstream nucleic acid detection device adopting a constant temperature amplification technology generally needs a worker to add an amplification reagent into a test tube filled with a nucleic acid sample, then a sealing cover closes an opening of the test tube, and after amplification is finished, the sealing cover is opened and test paper is put into the test tube, so that obviously, the risk of leakage of pollutants exists in the method; therefore, in the prior art, it is proposed to use a device to replace manual work, and to provide a pierceable sealing film at the opening of the test tube, and after the sealing film is pierced by the device, a test paper is added to the sealing film to complete the test.
Therefore, whether puncturing the sealing membrane by pure labor or by equipment, there is a risk of leakage of contaminants, and safety is low.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a low pressure formula nucleic acid detecting device solves among the prior art artifical uncap or puncture the problem that the detection means of seal membrane all has the risk that the pollutant was revealed through equipment.
To achieve the purpose, the utility model adopts the following technical proposal:
a low-pressure nucleic acid detecting apparatus includes a first sample storage unit and a second sample storage unit which are detachably connected; the first sample storage unit is provided with a sample storage groove, the second sample storage unit is internally provided with a sample storage cavity, and the wall of the sample storage cavity, which is close to the first sample storage unit, is provided with a first opening;
the second sample storage unit is movably provided with a piston unit for blocking the sample storage groove and the sample storage cavity; when the detection reaction is carried out, the piston unit can move along the direction close to the sample storage groove, so that the sample storage groove is communicated with the sample storage cavity.
Optionally, the piston unit includes a piston rod, a first baffle portion is disposed on the piston rod in a protruding manner, and a first sealing groove is disposed on a side wall surface of the first baffle portion; the inslot cover of first seal groove is equipped with first sealing washer, first sealing washer with the chamber wall butt of deposit kind cavity.
Optionally, a second opening is formed in the cavity wall of the sample storage cavity, which is far away from the first sample storage unit;
a sealing sleeve is sleeved at the second opening, a sealing hole is formed in the position, corresponding to the piston rod part, of the sealing sleeve, and a sealing bulge part is convexly arranged on the inner wall of the sealing hole; the piston rod part penetrates through the sealing hole to protrude out of the sample storage cavity, and the sealing bulge part is abutted to the piston rod part.
Optionally, the sealing kit includes a first sealing sleeve unit and a second sealing sleeve unit sleeved in the first sealing sleeve unit;
a second sealing groove is formed in the outer wall of the first sealing sleeve unit, a second sealing ring is sleeved on the second sealing groove, and the second sealing ring is abutted against the cavity wall of the sample storage cavity;
the sealing device is characterized in that a sealing and positioning part is convexly arranged on the inner wall of the first sealing sleeve unit, a positioning groove is formed in the outer wall of the second sealing sleeve unit, the positioning groove is embedded outside the sealing and positioning part, and the position, corresponding to the piston rod part, of the sealing hole is formed in the second sealing sleeve unit.
Optionally, a second baffle is further convexly arranged on the piston rod portion, and the second baffle is arranged in the sample storage cavity and abuts against the edge of the sealing hole.
Optionally, the second sample storage unit is detachably connected with a buffer base outside the second opening; the buffer base is provided with a buffer groove, and a buffer push block is convexly arranged at the position, corresponding to the piston rod part, of the groove bottom of the buffer groove;
when the buffer base is connected with the second sample storage unit, the piston rod part is pushed by the buffer push block along the direction far away from the sealing hole, and the sample storage cavity is communicated with the buffer groove.
Optionally, the second sample storage unit is provided with a buffer connecting portion extending outwards from one side of the second opening far away from the sample storage cavity; when the buffer base is connected with the second sample storage unit, the buffer base is sleeved in the buffer connecting part.
Optionally, a fourth seal groove is formed outside the buffer base, a fourth seal ring is sleeved in a groove of the fourth seal groove, and a fifth seal ring is arranged between the edge of the second opening and the buffer connecting part;
when the buffering base is connected with the second sample storage unit, the fourth sealing ring is abutted to the buffering connecting part, and the fifth sealing ring is pressed on the second sample storage unit by the buffering base.
Optionally, a third sealing groove is formed in the outer wall of the second sample storage unit, and a third sealing ring is sleeved on the third sealing groove;
and when the first sample storage unit and the second sample storage unit are used, the third sealing ring is abutted against the groove wall of the sample storage groove.
Optionally, an installation positioning portion is further convexly arranged on the outer wall of the second sample storage unit on one side of the third seal groove away from the first opening;
when the first sample storage unit is connected with the second sample storage unit, the notch edge of the sample storage groove is abutted to the installation positioning part.
Compared with the prior art, the utility model discloses following beneficial effect has:
the utility model provides a low pressure formula nucleic acid detecting device can put into the sample storage groove with amplification reagent and nucleic acid sample, then will store second sample storage unit and first sample storage unit connection that detect reagent in advance, because the setting of piston unit makes first sample storage unit sealed, is convenient for take place the amplification reaction between nucleic acid sample and the amplification reagent; after the amplification reaction is finished, moving the piston unit to enable the sample storage groove to be communicated with the sample storage cavity, and mixing the amplified nucleic acid sample with a detection reagent in the sample storage cavity to finish the detection reaction; in the process, the amplified nucleic acid sample and the detection reagent are mixed by changing the position of the piston unit, so that the condition of pressure mutation can be avoided, the peak value of internal pressure is reduced, the pollutants are not easy to seep out from the low-pressure nucleic acid detection device, and the safety is greatly improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the description below are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without inventive labor.
The structure, proportion, size and so on shown in the drawings of the present specification are only used to cooperate with the content disclosed in the specification for the understanding and reading of the people skilled in the art, and are not used to limit the limit conditions of the present invention, so that the present invention does not have the essential significance in the technology, and any structure modification, proportion relation change or size adjustment should still fall within the scope covered by the technical content disclosed in the present invention without affecting the function and the achievable by the present invention.
FIG. 1 is a schematic view of a first state structure of a low-pressure nucleic acid detecting apparatus according to an embodiment of the present invention;
FIG. 2 is a schematic diagram illustrating a second state of a low-pressure nucleic acid detecting apparatus according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a first cross-sectional structure of a low-pressure nucleic acid detecting apparatus according to an embodiment of the present invention;
FIG. 4 is an enlarged partial schematic view of FIG. 3 at A;
FIG. 5 is a partial enlarged view of FIG. 3 at B;
FIG. 6 is a schematic diagram of a second cross-sectional structure of a low-pressure nucleic acid detecting apparatus according to an embodiment of the present invention.
Illustration of the drawings: 10. a first sample storage unit; 11. a sample storage groove; 20. a second sample storage unit; 21. a sample storage cavity; 221. a first opening; 222. a second opening; 23. a third seal groove; 24. a buffer connection part; 25. installing a positioning part;
30. a piston unit; 31. a piston rod portion; 32. a first baffle portion; 33. a first seal groove; 34. a second baffle portion; 41. a first seal ring; 42. a second seal ring; 43. a third seal ring; 44. a fourth seal ring; 45. a fifth seal ring;
51. a first seal cartridge unit; 511. a second seal groove; 512. sealing the positioning part; 52. a second seal cartridge unit; 521. sealing the hole; 522. a seal boss; 523. positioning a groove; 60. a buffer base; 61. a buffer tank; 62. buffering the push block; 63. a fourth seal groove.
Detailed Description
In order to make the objects, features and advantages of the present invention more obvious and understandable, the drawings in the embodiments of the present invention are combined below to clearly and completely describe the technical solutions in the embodiments of the present invention, and obviously, the embodiments described below are only some embodiments of the present invention, but not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
In the description of the present invention, it should be understood that the terms "upper", "lower", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention. It should be noted that when one component is referred to as being "connected" to another component, it can be directly connected to the other component or intervening components may also be present.
The technical solution of the present invention is further explained by the following embodiments with reference to the drawings.
Please refer to fig. 1 to 6, fig. 1 is a schematic diagram of a first state structure of a low-voltage nucleic acid detecting device according to an embodiment of the present invention, fig. 2 is a schematic diagram of a second state structure of a low-voltage nucleic acid detecting device according to an embodiment of the present invention, fig. 3 is a schematic diagram of a first cross-sectional structure of a low-voltage nucleic acid detecting device according to an embodiment of the present invention, fig. 4 is a schematic diagram of a partially enlarged structure of fig. 3 at a, fig. 5 is a schematic diagram of a partially enlarged structure of fig. 3 at B, and fig. 6 is a schematic diagram of a second cross-sectional structure of a low-voltage nucleic acid detecting device according to an embodiment of the present invention.
The low-pressure nucleic acid detection device provided by the embodiment is applied to a nucleic acid amplification detection scene, can amplify and detect a nucleic acid sample, and has high safety because the structure is improved so that the nucleic acid sample is not easy to leak into the environment.
As shown in FIGS. 1 to 3, the low pressure type nucleic acid detecting apparatus of the present embodiment includes a first sample storage unit 10 and a second sample storage unit 20 detachably connected; the first sample storage unit 10 is provided with a sample storage groove 11, the second sample storage unit 20 is internally provided with a sample storage cavity 21, and the cavity wall of the sample storage cavity 21 close to the first sample storage unit 10 is provided with a first opening 221; the sample storage tank 11 is used for storing nucleic acid samples and amplification reagents, the sample storage cavity 21 is used for storing detection reagents, and correspondingly, a transparent observation window can be arranged on the wall surface of the second sample storage unit 20, so that a worker can observe color changes after detection reaction. In other alternative embodiments, the nucleic acid sample and the amplification reagent may be stored in the sample storage cavity 21, and the detection reagent may be stored in the sample storage tank 11 according to the variation of the usage scenario.
The second sample storage unit 20 is movably provided with a piston unit 30 for blocking the sample storage groove 11 and the sample storage cavity 21; wherein, when the detection reaction is performed, the piston unit 30 can move in a direction close to the sample storage tank 11, so that the sample storage tank 11 is communicated with the sample storage cavity 21.
Specifically, the amplification reagent and the nucleic acid sample can be put into the sample storage tank 11, and then the second sample storage unit 20 in which the detection reagent is pre-stored is connected with the first sample storage unit 10, due to the arrangement of the piston unit 30, the first sample storage unit 10 is sealed, so that the amplification reaction between the nucleic acid sample and the amplification reagent can be facilitated; after the amplification reaction is finished, moving the piston unit 30 to communicate the sample storage groove 11 with the sample storage cavity 21, and mixing the amplified nucleic acid sample with the detection reagent in the sample storage cavity 21 to complete the detection reaction; in the above process, the position of the piston unit 30 is changed to replace the mode of puncturing a sealing membrane in the prior art, so that the amplified nucleic acid sample and the detection reagent are mixed, the occurrence of pressure mutation can be avoided, the peak value of internal pressure is reduced, the pollutants are not easy to seep out from the low-pressure nucleic acid detection device, and the safety is greatly improved.
Further, as shown in fig. 3 and 4, the piston unit 30 includes a piston rod 31, a first baffle portion 32 is protruded from the piston rod 31, and a first sealing groove 33 is opened on a side wall surface of the first baffle portion 32; a first seal ring 41 is fitted in the first seal groove 33, and the first seal ring 41 abuts against the cavity wall of the sample storage cavity 21.
Specifically, when an amplification reaction is performed, the first sample storage unit 10 and the second sample storage unit 20 are connected, and the first baffle portion 32 abuts against the cavity wall of the sample storage cavity 21 via the first gasket 41 to seal the sample storage tank 11, thereby completing the amplification reaction between the amplification reagent and the nucleic acid sample in the sample storage tank 11; after the amplification reaction is completed, the first baffle portion 32 is moved out of the sample storage chamber 21 and protrudes from the first opening 221 by manually moving the piston rod portion 31, so that the amplified sample can flow into the sample storage chamber 21 from the sample storage tank 11. The first seal 41 is provided to improve the sealing between the sample storage tank 11 and the sample storage chamber 21.
In a specific embodiment, a second opening 222 is opened on the cavity wall of the sample storage cavity 21 away from the first sample storage unit 10; a sealing sleeve is sleeved at the second opening 222, a sealing hole 521 is formed in the position, corresponding to the piston rod portion 31, of the sealing sleeve, and a sealing protrusion 522 is convexly arranged on the inner wall of the sealing hole 521; the piston rod portion 31 protrudes from the sample storage chamber 21 through the seal hole 521, and the seal projection 522 abuts against the piston rod portion 31. Illustratively, when the detection reaction is performed, the plunger rod portion 31 is manually pushed out of the second opening 222 so that the first baffle portion 32 is moved out of the sample storage chamber 21 and protrudes out of the first opening 221 so that the amplified sample can flow from the sample storage tank 11 into the sample storage chamber 21. Wherein, by pushing the piston rod part 31 out of the second sample storage unit 20, the internal pressure variation can be reduced, so that the pressure transition of the amplified sample is smoother during the flow of the amplified sample from the sample storage tank 11 into the sample storage cavity 21.
In other alternative embodiments, the first sample storage unit 10 may be made of a transparent elastic material, and the first baffle portion 32 is provided with a protruding grabbing portion along a direction close to the first sample storage unit 10, so that a worker can indirectly grab the grabbing portion by pinching the first sample storage unit 10, so as to pull the first baffle portion 32 out of the first opening 221.
Further, as shown in fig. 3 and 5, the sealing kit includes a first sealing sleeve unit 51 and a second sealing sleeve unit 52 sleeved in the first sealing sleeve unit 51; a second sealing groove 511 is formed in the outer wall of the first seal sleeve unit 51, a second sealing ring 42 is sleeved on the second sealing groove 511, and the second sealing ring 42 is abutted against the cavity wall of the sample storage cavity 21; a sealing positioning portion 512 is convexly disposed on an inner wall of the first sealing sleeve unit 51, a positioning groove 523 is disposed on an outer wall of the second sealing sleeve unit 52, the positioning groove 523 is embedded outside the sealing positioning portion 512, and a position of the sealing hole 521 corresponding to the piston rod portion 31 is disposed on the second sealing sleeve unit 52. Through the arrangement, the sealing performance between the piston rod part 31 and the second opening 222 is enhanced, the structural complexity of the second sample storage unit 20 is reduced, and the manufacturing cost is reduced.
Further, as shown in fig. 5, the piston rod portion 31 is further provided with a second baffle portion 34 in a protruding manner, and the second baffle portion 34 is provided in the sample storage chamber 21 and abuts against the edge of the seal hole 521. Through the setting of second baffle 34, play the limiting displacement to piston rod portion 31 on the one hand, improved the stability of structure, on the other hand has improved the leakproofness, prevents that detect reagent from leaking from sealed hole 521.
Further, as shown in fig. 1, 2 and 6, the second sample storage unit 20 is detachably connected with a buffer base 60 outside the second opening 222; the buffer base 60 is provided with a buffer groove 61, and a buffer push block 62 is convexly arranged at the position of the groove bottom of the buffer groove 61 corresponding to the piston rod part 31.
Illustratively, when the buffer base 60 is connected to the second sample storage unit 20, the piston rod portion 31 is pushed by the buffer push block 62 in a direction away from the sealing hole 521, and the sample storage chamber 21 communicates with the buffer groove 61. By arranging the buffer base 60 to be a member for pushing the piston rod 31 for the last distance, when the buffer push block 62 completely pushes the piston rod 31 away from the seal hole 521, the detection sample can partially flow into the buffer groove 61, on one hand, the first baffle portion 32 is further pushed into the sample storage groove 11 to promote the mixing of the detection reagent and the amplified sample, on the other hand, the internal space of the low-pressure nucleic acid detection device is enlarged, so that the pressure is further reduced, and the leakage of the contaminant is effectively prevented.
Further, as shown in fig. 5, the second sample storage unit 20 is provided with a buffer connection portion 24 extending outward from a side of the second opening 222 away from the sample storage cavity 21; specifically, when the buffer base 60 is connected to the second sample storage unit 20, the buffer base 60 is sleeved in the buffer connecting portion 24, so that the sealing performance of the buffer groove 61 is effectively improved.
Further, as shown in fig. 6, a fourth seal groove 63 is formed outside the buffer base 60, a fourth seal ring 44 is sleeved in a groove of the fourth seal groove 63, and a fifth seal ring 45 is arranged between the edge of the second opening 222 and the buffer connecting portion 24; when the buffer base 60 is connected to the second sample storage unit 20, the fourth seal ring 44 abuts against the buffer connecting portion 24, the fifth seal ring 45 is pressed against the second sample storage unit 20 by the buffer base 60, and the sealing performance of the buffer groove 61 is further improved by the double seal arrangement of the fourth seal ring 44 and the fifth seal ring 45.
Further, as shown in fig. 4, a third sealing groove 23 is formed in the outer wall of the second sample storage unit 20, and a third sealing ring 43 is sleeved on the third sealing groove 23; specifically, when the first sample storage unit 10 and the second sample storage unit 20 are used, the third seal ring 43 abuts against the groove wall of the sample storage groove 11, and the sealing property between the first sample storage unit 10 and the second sample storage unit 20 is improved.
Further, as shown in fig. 4, on the side of the third sealing groove 23 away from the first opening 221, an installation positioning portion 25 is further protruded on the outer wall of the second sample storage unit 20; when the first sample storage unit 10 is connected with the second sample storage unit 20, the notch edge of the sample storage groove 11 is abutted with the installation positioning part 25, and the connection stability between the first sample storage unit 10 and the second sample storage unit 20 is improved.
In summary, the low-pressure nucleic acid detecting apparatus provided by this embodiment can complete amplification and detection of a nucleic acid sample under the premise of small internal pressure change, and has the advantages of difficult leakage of contaminants, high safety, stable structure, low manufacturing cost, and the like.
The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.
Claims (10)
1. A low-pressure nucleic acid detecting apparatus comprising a first sample storage unit (10) and a second sample storage unit (20) which are detachably connected; the first sample storage unit (10) is provided with a sample storage groove (11), the second sample storage unit (20) is internally provided with a sample storage cavity (21), and the cavity wall of the sample storage cavity (21) close to the first sample storage unit (10) is provided with a first opening (221);
the second sample storage unit (20) is movably provided with a piston unit (30) for blocking the sample storage groove (11) and the sample storage cavity (21); wherein, when the detection reaction is carried out, the piston unit (30) can move along the direction close to the sample storage groove (11) to enable the sample storage groove (11) to be communicated with the sample storage cavity (21).
2. The low pressure type nucleic acid detecting apparatus according to claim 1, wherein the piston unit (30) includes a piston rod portion (31), a first baffle portion (32) is protruded from the piston rod portion (31), and a first seal groove (33) is opened on a side wall surface of the first baffle portion (32); the inslot cover of first seal groove (33) is equipped with first sealing washer (41), first sealing washer (41) with the chamber wall butt of storing a kind cavity (21).
3. The low pressure type nucleic acid detecting device according to claim 2, wherein the sample storage chamber (21) has a second opening (222) formed on a wall thereof remote from the first sample storage unit (10);
a sealing sleeve is sleeved at the second opening (222), a sealing hole (521) is formed in the position, corresponding to the piston rod portion (31), of the sealing sleeve, and a sealing bulge (522) is arranged on the inner wall of the sealing hole (521) in a protruding mode; the piston rod part (31) passes through the sealing hole (521) and protrudes out of the sample storage cavity (21), and the sealing bulge part (522) is abutted against the piston rod part (31).
4. The low-pressure nucleic acid detecting device according to claim 3, wherein the sealing kit comprises a first sealing sleeve unit (51) and a second sealing sleeve unit (52) sleeved in the first sealing sleeve unit (51);
a second sealing groove (511) is formed in the outer wall of the first sealing sleeve unit (51), a second sealing ring (42) is sleeved on the second sealing groove (511), and the second sealing ring (42) is abutted to the cavity wall of the sample storage cavity (21);
the sealing device is characterized in that a sealing and positioning part (512) is convexly arranged on the inner wall of the first sealing sleeve unit (51), a positioning groove (523) is formed in the outer wall of the second sealing sleeve unit (52), the positioning groove (523) is embedded outside the sealing and positioning part (512), and the position, corresponding to the piston rod part (31), of the sealing hole (521) is arranged on the second sealing sleeve unit (52).
5. The low pressure type nucleic acid detecting apparatus according to claim 3, wherein a second baffle portion (34) is further protruded from the piston rod portion (31), and the second baffle portion (34) is provided in the sample storage chamber (21) and abuts against an edge of the seal hole (521).
6. The low pressure type nucleic acid detecting apparatus according to claim 3, wherein a buffer base (60) is detachably attached to the second sample storage unit (20) outside the second opening (222); the buffer base (60) is provided with a buffer groove (61), and a buffer push block (62) is convexly arranged at the position, corresponding to the piston rod part (31), of the groove bottom of the buffer groove (61);
when the buffer base (60) is connected with the second sample storage unit (20), the piston rod part (31) is pushed by the buffer push block (62) along the direction away from the sealing hole (521), and the sample storage cavity (21) is communicated with the buffer groove (61).
7. The low pressure type nucleic acid detecting device according to claim 6, wherein the second sample storage unit (20) is provided with a buffer connecting portion (24) extending outward from a side of the second opening (222) away from the sample storage chamber (21); when the buffer base (60) is connected with the second sample storage unit (20), the buffer base (60) is sleeved in the buffer connecting part (24).
8. The low pressure type nucleic acid detecting apparatus according to claim 7, wherein a fourth sealing groove (63) is formed outside the buffer base (60), a fourth sealing ring (44) is fitted in a groove of the fourth sealing groove (63), and a fifth sealing ring (45) is disposed between an edge of the second opening (222) and the buffer connecting portion (24);
when the buffer base (60) is connected with the second sample storage unit (20), the fourth sealing ring (44) is abutted against the buffer connecting part (24), and the fifth sealing ring (45) is pressed on the second sample storage unit (20) by the buffer base (60).
9. The low-pressure nucleic acid detecting device according to claim 1, wherein a third sealing groove (23) is formed in an outer wall of the second sample storage unit (20), and a third sealing ring (43) is sleeved on the third sealing groove (23);
when the first sample storage unit (10) and the second sample storage unit (20) are used, the third sealing ring (43) is abutted against the groove wall of the sample storage groove (11).
10. The low pressure type nucleic acid detecting apparatus according to claim 9, wherein an installation positioning portion (25) is further protruded from an outer wall of the second sample storage unit (20) on a side of the third seal groove (23) away from the first opening (221);
when the first sample storage unit (10) is connected with the second sample storage unit (20), the notch edge of the sample storage groove (11) is abutted against the installation positioning part (25).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222578528.XU CN218404215U (en) | 2022-09-28 | 2022-09-28 | Low pressure formula nucleic acid detection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222578528.XU CN218404215U (en) | 2022-09-28 | 2022-09-28 | Low pressure formula nucleic acid detection device |
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| CN218404215U true CN218404215U (en) | 2023-01-31 |
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| CN202222578528.XU Active CN218404215U (en) | 2022-09-28 | 2022-09-28 | Low pressure formula nucleic acid detection device |
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