CN218232412U - Vertical nucleic acid detection heating device of single channel - Google Patents
Vertical nucleic acid detection heating device of single channel Download PDFInfo
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- CN218232412U CN218232412U CN202221836266.6U CN202221836266U CN218232412U CN 218232412 U CN218232412 U CN 218232412U CN 202221836266 U CN202221836266 U CN 202221836266U CN 218232412 U CN218232412 U CN 218232412U
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Abstract
The utility model relates to a nucleic acid testing constant temperature heating technology field, in particular to vertical nucleic acid testing heating device of single channel, including heating casing and spacing seat, the heating casing inner chamber is equipped with supporting seat, heat conductor, semiconductor refrigeration piece and fin, and the heat conductor, semiconductor refrigeration piece and fin are all installed on the supporting seat, and the semiconductor refrigeration piece is attached on a side of heat conductor, the fin is attached on a side that the heat conductor was kept away from to the semiconductor refrigeration piece, examines time measuring at nucleic acid, can put the nucleic acid micro-fluidic chip who is equipped with the nucleic acid sample in the heating cavity in the holding tank of spacing seat, places the back that finishes, for the circular telegram of semiconductor refrigeration piece, the semiconductor refrigeration piece starts the heating function and carries out automatic constant temperature heating to nucleic acid micro-fluidic chip, and then when cooling down again, the semiconductor refrigeration piece starts the refrigeration function, and the fin dispels the heat for the semiconductor refrigeration piece to can realize the temperature fast switch-over, improve the efficiency of nucleic acid testing.
Description
Technical Field
The utility model relates to a nucleic acid detects constant temperature heating technical field, in particular to vertical nucleic acid detection heating device of single channel.
Background
The nucleic acid detection is to find out whether the respiratory tract specimen, blood or feces of the patient have nucleic acid of the exogenous invading virus to determine whether the patient is infected by the virus;
the isothermal amplification technology of nucleic acid is a new auxiliary technology for in vitro detection, and is watched by more and more inspection and quarantine personnel. Compared with the traditional Polymerase Chain Reaction (PCR), the isothermal amplification method has the advantages of strong specificity, rapid detection, simple operation and the like, and is widely used for nucleic acid detection of bacteria and viruses. After the detection of the existing isothermal amplification detector is finished, the detection reagent is inconvenient to take out due to the high internal temperature, so that a detector can only take out after the internal temperature of the detector is naturally reduced to the room temperature range, and the detection efficiency of the detector is greatly reduced.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects of the prior art, the utility model aims to solve the technical problems that: the utility model provides a vertical nucleic acid detection heating device of single channel can realize the inside temperature switch of detecting instrument fast to improve nucleic acid detection efficiency.
In order to solve the technical problem, the utility model discloses a technical scheme be:
a single-channel vertical nucleic acid detection heating device comprises a heating shell and a limiting seat, wherein a supporting seat, a heat conductor, a semiconductor refrigerating sheet and a radiating sheet are arranged in an inner cavity of the heating shell, the heat conductor, the semiconductor refrigerating sheet and the radiating sheet are all arranged on the supporting seat, the semiconductor refrigerating sheet is attached to one side face of the heat conductor, and the radiating sheet is attached to one side face, far away from the heat conductor, of the semiconductor refrigerating sheet;
spacing seat inlays to be established on heating housing and spacing seat is located the heat conductor directly over, a side that the inside cavity of heat conductor and heat conductor are close to spacing seat has the opening, the one end of spacing seat extends to heating housing outside, the other end that the one end is relative of spacing seat extends heating housing inner chamber lid and establishes the opening part at the heat conductor, be equipped with the holding tank that is used for placing nucleic acid micro-fluidic chip on the spacing seat, the opening to the heat conductor inner chamber of holding tank and heat conductor is passed in proper order to the one end of nucleic acid micro-fluidic chip, the symmetry is equipped with the stopper respectively on nucleic acid micro-fluidic chip's the relative both sides face, be equipped with the spacing groove that is used for placing the stopper on the two relative cell walls of holding tank.
Furthermore, the supporting seat is installed in the inner cavity of the heating shell through four isolation columns, and the isolation columns are made of nylon.
Furthermore, grooves are formed in the other two opposite groove walls of the accommodating groove.
Further, the heat conductor is made of aluminum.
The beneficial effects of the utility model reside in that:
the utility model discloses when nucleic acid detects, can put the nucleic acid micro-fluidic chip that is equipped with the nucleic acid sample in the heating cavity in the holding tank of spacing seat, after placing, put the back that finishes, for the circular telegram of semiconductor refrigeration piece, semiconductor refrigeration piece starts the heating function and carries out automatic constant temperature heating to nucleic acid micro-fluidic chip, then when the cooling, semiconductor refrigeration piece starts the refrigeration function, the fin dispels the heat for the semiconductor refrigeration piece, thereby can realize the temperature fast switch-over, can take out nucleic acid micro-fluidic chip after the convenient detection finishes fast, improve the efficiency that nucleic acid detected.
Drawings
FIG. 1 is a schematic structural diagram of a single-channel vertical nucleic acid detecting and heating device according to the present invention;
FIG. 2 is a schematic view of a partial structure of a single-channel vertical heating device for nucleic acid detection according to the present invention;
FIG. 3 is a schematic view of a partial structure of a single-channel vertical nucleic acid detecting and heating device according to the present invention;
fig. 4 is a schematic structural diagram of a nucleic acid microfluidic chip of a single-channel vertical nucleic acid detection heating device according to the present invention;
description of reference numerals:
1. heating the shell; 2. a limiting seat; 21. accommodating grooves; 22. a limiting groove; 23. a groove; 3. a supporting seat; 4. a heat conductor; 5. a semiconductor refrigeration sheet; 6. a heat sink; 7. a nucleic acid microfluidic chip; 71. a limiting block; 8. and (4) isolating columns.
Detailed Description
In order to explain the technical content, the objects and the effects of the present invention in detail, the following description is made with reference to the accompanying drawings in combination with the embodiments.
Referring to fig. 1, the technical solution provided by the present invention is:
a single-channel vertical nucleic acid detection heating device comprises a heating shell and a limiting seat, wherein a supporting seat, a heat conductor, a semiconductor refrigerating sheet and a radiating fin are arranged in an inner cavity of the heating shell, the heat conductor, the semiconductor refrigerating sheet and the radiating fin are all arranged on the supporting seat, the semiconductor refrigerating sheet is attached to one side face of the heat conductor, and the radiating fin is attached to one side face, far away from the heat conductor, of the semiconductor refrigerating sheet;
spacing seat inlays to be established on heating housing and spacing seat is located the heat conductor directly over, a side that the inside cavity of heat conductor and heat conductor are close to spacing seat has the opening, the one end of spacing seat extends to heating housing outside, the other end that the one end is relative of spacing seat extends heating housing inner chamber lid and establishes the opening part at the heat conductor, be equipped with the holding tank that is used for placing nucleic acid micro-fluidic chip on the spacing seat, the opening to the heat conductor inner chamber of holding tank and heat conductor is passed in proper order to the one end of nucleic acid micro-fluidic chip, the symmetry is equipped with the stopper respectively on nucleic acid micro-fluidic chip's the relative both sides face, be equipped with the spacing groove that is used for placing the stopper on the two relative cell walls of holding tank.
From the above description, the beneficial effects of the utility model reside in that:
the utility model discloses when nucleic acid detects, can put the nucleic acid micro-fluidic chip that is equipped with the nucleic acid sample in the heating cavity in the holding tank of spacing seat, after placing, put the back that finishes, for the circular telegram of semiconductor refrigeration piece, semiconductor refrigeration piece starts the heating function and carries out automatic constant temperature heating to nucleic acid micro-fluidic chip, then when the cooling, semiconductor refrigeration piece starts the refrigeration function, the fin dispels the heat for the semiconductor refrigeration piece, thereby can realize the temperature fast switch-over, can take out nucleic acid micro-fluidic chip after the convenient detection finishes fast, improve the efficiency that nucleic acid detected.
Furthermore, the supporting seat is installed in the inner cavity of the heating shell through four isolation columns, and the isolation columns are made of nylon.
Furthermore, grooves are formed in the other two opposite groove walls of the accommodating groove.
From the above description, it can be known that the taking and placing of the nucleic acid microfluidic chip can be facilitated by providing the grooves on the other two opposite groove walls of the holding groove.
Furthermore, the heat conductor is made of aluminum.
Referring to fig. 1 to 4, a first embodiment of the present invention is:
referring to fig. 1 to 4, a single-channel vertical nucleic acid detecting and heating device includes a heating shell 1 and a limiting seat 2, wherein a supporting seat 3, a heat conductor 4, a semiconductor refrigerating sheet 5 and a heat sink 6 are arranged in an inner cavity of the heating shell 1, the heat conductor 4, the semiconductor refrigerating sheet 5 and the heat sink 6 are all mounted on the supporting seat 3, the semiconductor refrigerating sheet 5 is attached to one side surface of the heat conductor 4, and the heat sink 6 is attached to one side surface of the semiconductor refrigerating sheet 5 away from the heat conductor 4;
referring to fig. 1 to 4, the limiting seat 2 is embedded in the heating housing 1, the limiting seat 2 is located right above the heat conductor 4, the heat conductor 4 is hollow, an opening is formed in a side surface of the heat conductor 4 close to the limiting seat 2, one end of the limiting seat 2 extends to the outside of the heating housing 1, the other end of the limiting seat 2 opposite to the one end extends to an inner cavity of the heating housing 1 and covers the opening of the heat conductor 4, an accommodating groove 21 for accommodating the nucleic acid microfluidic chip 7 is formed in the limiting seat 2, one end of the nucleic acid microfluidic chip 7 sequentially passes through the accommodating groove 21 and the opening of the heat conductor 4 to the inner cavity of the heat conductor 4, limiting blocks 71 are symmetrically arranged on two opposite side surfaces of the nucleic acid microfluidic chip 7, and limiting grooves for accommodating the limiting blocks 71 are formed in two opposite groove walls of the accommodating groove 21.
Referring to fig. 1 to 3, the supporting base 3 is installed in the inner cavity of the heating casing 1 through four isolation pillars 8, and the isolation pillars 8 are made of nylon. The nylon support accommodating groove heating structure can isolate a heat source and a power supply, and the space reserved at the bottom can be used for fixing a power adapter; the nylon has excellent mechanical property, high mechanical strength, good toughness, good electrical insulation and heat resistance.
The other two opposite groove walls of the accommodating groove 21 are provided with grooves 23.
The heat conductor 4 is made of aluminum.
The nucleic acid microfluidic chip 7 is a microfluidic chip capable of carrying out nucleic acid sample reagent reaction in the prior art, and has the following specific structure: including detecting the piece, be equipped with the introduction port on detecting the piece, it still is equipped with a plurality of reaction zone still to detect the piece inner chamber, reaction solution has been placed in the reaction zone, reaction zone and introduction port intercommunication, after the introduction port was added to sample reagent, the sealed lid of accessible lived the introduction port lid sealed.
The working principle of the single-channel vertical nucleic acid detection heating device is as follows:
when a nucleic acid sample needs to be detected, the nucleic acid microfluidic chip 7 filled with the nucleic acid sample is placed in the holding groove 21 of the limiting seat 2, one end of the nucleic acid microfluidic chip 7 sequentially penetrates through the holding groove 21 and the opening of the heating body to the inner cavity of the heating body, the limiting block 71 and the end arranged on the nucleic acid microfluidic chip 7 are just clamped in the limiting grooves arranged on the two opposite groove walls of the holding groove 21, and the end without a reaction area on the nucleic acid microfluidic chip 7 can be fixed so as to be taken out after reaction;
after the nucleic acid sample is placed, the semiconductor refrigerating sheet 5 is electrified, the semiconductor refrigerating sheet 5 starts a heating function, the semiconductor refrigerating sheet 5 transfers the generated heat to the heat conductor 4, and the heat conductor 4 provides heat required by nucleic acid sample detection for heating the nucleic acid microfluidic chip 7 at a constant temperature; after the high-temperature heating stage is finished, the semiconductor refrigerating sheet 5 starts a refrigerating function, and the radiating fins 6 radiate heat to the semiconductor refrigerating sheet 5, so that the temperature can be quickly switched to a low-temperature state, and the nucleic acid micro-fluidic chip 7 can be quickly taken out;
after the reaction of the sample reagent is finished, the nucleic acid micro-fluidic chip 7 is taken out; the color of the reaction area can be observed by the staff through naked eyes so as to judge the detection result.
To sum up, the utility model provides a pair of vertical nucleic acid detection heating device of single channel can put the nucleic acid micro-fluidic chip who is equipped with the nucleic acid sample in the heating cavity in the holding tank of spacing seat, place the back that finishes, for the circular telegram of semiconductor refrigeration piece, semiconductor refrigeration piece starts the heating function and carries out automatic constant temperature heating to nucleic acid micro-fluidic chip, then when the cooling, semiconductor refrigeration piece starts the refrigeration function, the fin gives the semiconductor refrigeration piece heat dissipation, thereby can realize the temperature fast switch-over, conveniently detect can take out nucleic acid micro-fluidic chip fast after finishing, improve the efficiency that nucleic acid detected.
The above mentioned is only the embodiment of the present invention, and not the limitation of the patent scope of the present invention, all the equivalent transformations made by the contents of the specification and the drawings, or the direct or indirect application in the related technical field, are included in the patent protection scope of the present invention.
Claims (4)
1. A single-channel vertical nucleic acid detection heating device is characterized by comprising a heating shell and a limiting seat, wherein a supporting seat, a heat conductor, a semiconductor refrigerating sheet and a radiating sheet are arranged in an inner cavity of the heating shell, the heat conductor, the semiconductor refrigerating sheet and the radiating sheet are all arranged on the supporting seat, the semiconductor refrigerating sheet is attached to one side face of the heat conductor, and the radiating sheet is attached to one side face, far away from the heat conductor, of the semiconductor refrigerating sheet;
the spacing seat is embedded on the heating shell and is located directly over the heat conductor, a side face of the heat conductor close to the spacing seat is provided with an opening, one end of the spacing seat extends to the outside of the heating shell, the other end, opposite to one end of the spacing seat, extends to the inner cavity of the heating shell and covers the opening of the heat conductor, the spacing seat is provided with a containing groove used for containing the nucleic acid micro-fluidic chip, one end of the nucleic acid micro-fluidic chip sequentially penetrates through the containing groove and the opening of the heat conductor to the inner cavity of the heat conductor, the opposite side faces of the nucleic acid micro-fluidic chip are respectively and symmetrically provided with limiting blocks, and two opposite groove walls of the containing groove are provided with limiting grooves used for containing the limiting blocks.
2. The single-channel vertical nucleic acid detection heating device according to claim 1, wherein the support base is mounted in the inner cavity of the heating housing via four isolation pillars, and the isolation pillars are made of nylon.
3. The single-channel vertical nucleic acid detecting and heating device according to claim 1, wherein grooves are formed on the other two opposite walls of the accommodating chamber.
4. The single-channel vertical nucleic acid detection and heating device of claim 1, wherein the heat conductor is made of aluminum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221836266.6U CN218232412U (en) | 2022-07-15 | 2022-07-15 | Vertical nucleic acid detection heating device of single channel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221836266.6U CN218232412U (en) | 2022-07-15 | 2022-07-15 | Vertical nucleic acid detection heating device of single channel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218232412U true CN218232412U (en) | 2023-01-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221836266.6U Active CN218232412U (en) | 2022-07-15 | 2022-07-15 | Vertical nucleic acid detection heating device of single channel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218232412U (en) |
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2022
- 2022-07-15 CN CN202221836266.6U patent/CN218232412U/en active Active
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