CN217709442U - A kind of nano fat separation, extraction, concentration and purification device - Google Patents

A kind of nano fat separation, extraction, concentration and purification device Download PDF

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CN217709442U
CN217709442U CN202221323103.8U CN202221323103U CN217709442U CN 217709442 U CN217709442 U CN 217709442U CN 202221323103 U CN202221323103 U CN 202221323103U CN 217709442 U CN217709442 U CN 217709442U
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fat
separation
suction
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tube
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李建宇
刘念
李莉
邱华蕊
艾芳芳
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Jiasite Medical Equipment Tianjin Co ltd
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Abstract

本实用新型涉及医疗器械技术领域,尤其涉及一种纳米脂肪的分离提取与浓缩纯化装置,其包括脂肪抽吸管、分离纯化管及负压抽吸装置,脂肪抽吸管位于分离纯化管上方且与分离纯化管之间通过鲁尔三通阀连通,分离纯化管内安装有过滤网筒,负压抽吸装置包括芯杆、活塞及负压抽吸接口,芯杆从分离纯化管底部伸入到过滤网筒内,且芯杆上部开设有吸气孔,活塞固装于芯杆顶部,负压抽吸接口位于芯杆底部且伸出分离纯化管。本实用新型提供的装置结构简单,体积小,重量轻,操作方便省力,制备的纳米活性脂肪具有纯度高、活性好的优势,能够减少注射时引起不良反应。

Figure 202221323103

The utility model relates to the technical field of medical devices, in particular to a device for separating, extracting, concentrating and purifying nano fat, which comprises a fat suction tube, a separation and purification tube and a negative pressure suction device, wherein the fat suction tube is located above the separation and purification tube and It is communicated with the separation and purification tube through a Luer three-way valve. The separation and purification tube is installed with a filter screen cartridge. The negative pressure suction device includes a core rod, a piston and a negative pressure suction interface. The core rod extends from the bottom of the separation and purification tube to the Inside the filter mesh cylinder, and the upper part of the core rod is provided with a suction hole, the piston is fixed on the top of the core rod, and the negative pressure suction interface is located at the bottom of the core rod and extends out of the separation and purification tube. The device provided by the utility model has the advantages of simple structure, small volume, light weight, convenient operation and labor saving, and the prepared nanometer active fat has the advantages of high purity and good activity, and can reduce adverse reactions caused during injection.

Figure 202221323103

Description

一种纳米脂肪的分离提取与浓缩纯化装置A device for separating, extracting, concentrating and purifying nano-fat

技术领域technical field

本实用新型涉及医疗器械技术领域,尤其涉及一种纳米脂肪的分离提取与浓缩纯化装置。The utility model relates to the technical field of medical devices, in particular to a device for separating, extracting, concentrating and purifying nano fat.

背景技术Background technique

纳米脂肪是将取出的脂肪进行初步提纯后,将已经成熟的脂肪细胞,也就是含有大颗粒油滴的脂肪细胞破坏掉,这一类脂肪填充后不易成活,并且大颗粒的油滴还容易引起肿胀等炎症反应。存留下的体积较小的脂肪细胞填充后成活率相比来说较高,纳米脂肪是微小颗粒的脂肪团通常其直径只有0.4-0.6mm,目前纳米脂肪被广泛的应用到脂肪移植领域。Nano-fat is to preliminarily purify the extracted fat, and then destroy the mature fat cells, that is, the fat cells containing large particles of oil droplets. This type of fat is not easy to survive after filling, and large particles of oil droplets are easy to cause Inflammatory reactions such as swelling. The remaining small fat cells have a relatively high survival rate after filling. Nanofat is a fat mass with tiny particles, usually with a diameter of only 0.4-0.6mm. At present, nanofat is widely used in the field of fat transplantation.

纳米脂肪细胞分离提取及浓缩纯化时,经常需要比较复杂的系统进行处理,系统结构比较复杂且笨重,操作程序也很繁复,提取成本比较高,效率低,而且提取的包含脂肪干细胞等活性脂肪组织纯度不高,活性较差,注射时容易引起不良反应。When separating, extracting, concentrating and purifying nano-adipocytes, a complex system is often required for processing. The system structure is complex and cumbersome, and the operating procedures are also very complicated. The extraction cost is relatively high and the efficiency is low, and the extracted active adipose tissue contains adipose stem cells. The purity is not high, the activity is poor, and it is easy to cause adverse reactions when injected.

实用新型内容Utility model content

本实用新型所要解决的技术问题是提供结构简单,体积小,重量轻,操作方便省力的一种纳米脂肪的分离提取与浓缩纯化装置,制备的纳米活性脂肪具有纯度高、活性好的优势,能够减少注射时引起不良反应。The technical problem to be solved by the utility model is to provide a nano-fat separation, extraction, concentration and purification device with simple structure, small volume, light weight, convenient operation and labor-saving. The prepared nano-active fat has the advantages of high purity and good activity, and can To reduce adverse reactions caused by injection.

本实用新型是通过以下技术方案予以实现:The utility model is realized through the following technical solutions:

一种纳米脂肪的分离提取与浓缩纯化装置,其包括脂肪抽吸管、分离纯化管及负压抽吸装置,所述脂肪抽吸管位于分离纯化管上方且与分离纯化管之间通过鲁尔三通阀连通,所述分离纯化管内安装有过滤网筒,所述负压抽吸装置包括芯杆、活塞及负压抽吸接口,所述芯杆从分离纯化管底部伸入到过滤网筒内,且芯杆上部开设有吸气孔,所述活塞固定安装于芯杆顶部,所述负压抽吸接口位于芯杆底部且伸出分离纯化管。A device for separating, extracting, concentrating and purifying nano-fat, which includes a fat suction tube, a separation and purification tube and a negative pressure suction device, the fat suction tube is located above the separation and purification tube and passes through a Luer tube between the separation and purification tube The three-way valve is connected, and a filter screen cylinder is installed in the separation and purification pipe. The negative pressure suction device includes a core rod, a piston and a negative pressure suction interface. The core rod extends from the bottom of the separation and purification pipe into the filter screen cylinder. Inside, and the upper part of the core rod is provided with a suction hole, the piston is fixedly installed on the top of the core rod, and the negative pressure suction port is located at the bottom of the core rod and extends out of the separation and purification tube.

进一步,脂肪抽吸管包括抽吸管体及抽吸管底座,所述抽吸管体上部开设有脂肪抽吸孔,抽吸管底座包括连接管及卡托,所述卡托卡装在鲁尔三通阀顶部,连接管固定穿过卡托并与抽吸管体及鲁尔三通阀连通。Further, the fat suction tube includes a suction tube body and a suction tube base, and the upper part of the suction tube body is provided with a fat suction hole, and the suction tube base includes a connecting tube and a card support, and the card support card is installed in the Lu The top of the Luer three-way valve, the connecting pipe is fixed through the card holder and communicated with the suction pipe body and the Luer three-way valve.

进一步,分离纯化管顶部设有收集口,底部固定安装有封板,所述鲁尔三通阀安装在分离纯化管的收集口上。Further, the top of the separation and purification pipe is provided with a collection port, and the bottom is fixedly installed with a sealing plate, and the Luer three-way valve is installed on the collection port of the separation and purification pipe.

进一步,芯杆在负压抽吸接口的上方固定安装有按手。Further, the core rod is fixedly installed with a presser handle above the negative pressure suction interface.

优化的,鲁尔三通阀设有鲁尔接口。Optimized, Luer 3-way valve with Luer connection.

优化的,负压抽吸接口为螺纹斜口。Optimized, the negative pressure suction port is a threaded oblique port.

优化的,脂肪抽吸孔为多个。Optimized, there are multiple liposuction holes.

本实用新型的有益效果Beneficial effects of the utility model

本实用新型提供的一种纳米脂肪的分离提取与浓缩纯化装置,具有如下优点:本装置结构简单,体积小,重量轻,操作方便省力,并且可在保留纳米脂肪组织活性的基础上进行高效的分离提取,并通过纯化与浓缩纳米脂肪提高其生物活性,减少其注射引起的不良反应,本装置制备的纳米脂肪具有纯度高、活性好的优势,适用于整形外科、关节外科等医疗领域的应用。The utility model provides a device for separating, extracting, concentrating and purifying nano-fat, which has the following advantages: the device is simple in structure, small in size, light in weight, easy to operate and labor-saving, and can carry out high-efficiency extraction on the basis of retaining the activity of nano-fat tissue. Separation and extraction, and by purifying and concentrating the nano-fat to improve its biological activity and reduce the adverse reactions caused by its injection, the nano-fat prepared by this device has the advantages of high purity and good activity, and is suitable for applications in medical fields such as plastic surgery and joint surgery .

附图说明Description of drawings

图1是本实用新型脂肪组织抽吸状态结构示意图;Fig. 1 is a schematic diagram of the structure of the adipose tissue suction state of the utility model;

图2是本实用新型脂肪组织对冲状态结构示意图;Fig. 2 is a schematic diagram of the structure of the hedging state of the adipose tissue of the present invention;

图中1.脂肪抽吸孔,2.抽吸管体,3.抽吸管底座,4.鲁尔三通阀,5.收集口,6.分离纯化管,7.过滤网筒,8.活塞,9.吸气孔,10.芯杆,11.封板,12.按手,13.负压抽吸接口,14.第一鲁尔注射器,15.第二鲁尔注射器,16.卡托,17.连接管。In the figure 1. Fat suction hole, 2. Suction tube body, 3. Suction tube base, 4. Luer three-way valve, 5. Collection port, 6. Separation and purification tube, 7. Filter mesh cylinder, 8. Piston, 9. Suction hole, 10. Core rod, 11. Seal plate, 12. Press hand, 13. Negative pressure suction port, 14. First Luer syringe, 15. Second Luer syringe, 16. Card Support, 17. Connect the pipe.

具体实施方式Detailed ways

一种纳米脂肪的分离提取与浓缩纯化装置,其包括脂肪抽吸管、分离纯化管6及负压抽吸装置,所述脂肪抽吸管位于分离纯化管上方且与分离纯化管之间通过鲁尔三通阀4连通,脂肪抽吸管可以进入人体脂肪组织,将脂肪组织抽出并通过鲁尔三通阀经脂肪组织送入分离纯化管内。A nano-fat separation, extraction and concentration purification device, which includes a fat suction tube, a separation and purification tube 6, and a negative pressure suction device, the fat suction tube is located above the separation and purification tube and passes through the separation and purification tube. The Luer three-way valve 4 is connected, and the fat suction tube can enter the fat tissue of the human body, and the fat tissue is drawn out and sent into the separation and purification tube through the fat tissue through the Luer three-way valve.

分离纯化管内安装有过滤网筒7,过滤网筒可以将分离纯化后的组织与分离出的液体油滴进行过滤分离。所述负压抽吸装置包括芯杆10、活塞8及负压抽吸接口13,所述芯杆从分离纯化管底部伸入到过滤网筒内,且芯杆上部开设有吸气孔9,所述活塞固定安装于芯杆顶部,所述负压抽吸接口位于芯杆底部且伸出分离纯化管。负压抽吸接口与负压泵(未示出)连通,可以将分离纯化管内抽成负压,方便将脂肪组织从人体内吸出沿着脂肪抽吸管及鲁尔三通阀进入到分离纯化管内进行分离提取及浓缩纯化。A filter screen cylinder 7 is installed in the separation and purification tube, and the filter screen cylinder can filter and separate the separated and purified tissue from the separated liquid oil droplets. The negative pressure suction device comprises a core rod 10, a piston 8 and a negative pressure suction interface 13, the core rod extends into the filter screen cylinder from the bottom of the separation and purification pipe, and the upper part of the core rod is provided with an air suction hole 9, The piston is fixedly installed on the top of the core rod, and the negative pressure suction port is located at the bottom of the core rod and extends out of the separation and purification tube. The negative pressure suction interface is connected with a negative pressure pump (not shown), and the separation and purification tube can be pumped into a negative pressure to facilitate the suction of fat tissue from the human body along the fat suction tube and Luer three-way valve into the separation and purification tube. Separation, extraction, concentration and purification are carried out in the tube.

进一步,脂肪抽吸管包括抽吸管体2及抽吸管底座3,所述抽吸管体上部开设有脂肪抽吸孔1,抽吸管底座包括连接管17及卡托16,所述卡托卡装在鲁尔三通阀顶部,连接管固定穿过卡托并与抽吸管体及鲁尔三通阀连通。卡托的设置既方便与鲁尔三通阀形成稳固连接,使脂肪组织顺利通过鲁尔三通阀进入到分离纯化管内,又方便抽吸完毕后快速将脂肪抽吸管从鲁尔三通阀取下,进行下一步的分离提取及浓缩纯化操作。抽吸管底座可以一体成型,制作安装方便,且结构稳固。Further, the fat suction tube includes a suction tube body 2 and a suction tube base 3, the upper part of the suction tube body is provided with a fat suction hole 1, and the suction tube base includes a connecting pipe 17 and a card holder 16, and the card holder The toca is installed on the top of the Luer three-way valve, and the connecting pipe is fixed through the card to communicate with the suction pipe body and the Luer three-way valve. The setting of Cato is convenient to form a stable connection with the Luer three-way valve, so that the adipose tissue can pass through the Luer three-way valve smoothly into the separation and purification tube, and it is also convenient to quickly remove the fat suction tube from the Luer three-way valve after the suction is completed. Take it off and proceed to the next step of separation, extraction, concentration and purification. The base of the suction pipe can be integrally formed, which is easy to manufacture and install, and has a stable structure.

进一步,分离纯化管顶部设有收集口5,底部固定安装有封板11,所述鲁尔三通阀安装在分离纯化管的收集口上,安装方便快捷,并且防止脂肪组织发生泄漏,封板的设置方便负压发生装置的固定安装。Further, the top of the separation and purification tube is provided with a collection port 5, and the bottom is fixedly equipped with a sealing plate 11. The Luer three-way valve is installed on the collection port of the separation and purification tube, which is convenient and quick to install, and prevents fat tissue from leaking. The setting facilitates the fixed installation of the negative pressure generating device.

进一步,芯杆在负压抽吸接口的上方固定安装有按手12,脂肪组织抽吸完毕,可以握住按手向上推压芯杆,使得活塞沿着过滤网筒向上运动,将脂肪组织推送至鲁尔三通阀内进行分离提取及浓缩纯化操作。Further, the core rod is fixedly installed with a pressing hand 12 above the negative pressure suction interface. After the fat tissue is sucked, you can hold the pressing hand and push the core rod upward, so that the piston moves upward along the filter cylinder to push the fat tissue To the Luer three-way valve for separation, extraction, concentration and purification operations.

优化的,鲁尔三通阀设有鲁尔接口,方便与脂肪抽吸管、分离纯化管及鲁尔注射器的快速连接与脱离。Optimized, the Luer three-way valve is equipped with a Luer interface, which is convenient for quick connection and disconnection with the fat suction tube, separation and purification tube and Luer syringe.

优化的,负压抽吸接口为螺纹斜口,方便与负压抽吸接口与负压泵的快速紧密连接,防止脱落或泄漏。The optimized negative pressure suction interface is a threaded oblique port, which is convenient for fast and tight connection with the negative pressure suction interface and the negative pressure pump to prevent falling off or leakage.

优化的,脂肪抽吸孔为多个,可以进一步加快脂肪抽吸速度。Optimized, there are multiple liposuction holes, which can further speed up the liposuction speed.

本实用新型保护的一种纳米脂肪的分离提取与浓缩纯化装置,需要对脂肪组织进行分离提取与浓缩纯化时,首先将脂肪抽吸管安装在鲁尔三通阀上,脂肪抽吸管顶部进入脂肪组织,鲁尔三通阀处于脂肪抽吸管与分离纯化管接通状态,然后负压抽吸接口与负压泵连通且负压泵工作,将分离纯化管内抽成负压状态,使脂肪组织快速从脂肪抽吸管通过鲁尔三通阀进入到分离纯化管内。然后负压泵停止工作,并将其与负压抽吸接口脱离,脂肪抽吸管从鲁尔三通阀上取下,再在鲁尔三通阀的两个鲁尔接头上分别安装第一鲁尔注射器14、第二鲁尔注射器15,通过鲁尔三通阀进行反复对冲,将脂肪颗粒进行机械乳化,产生的液体油滴经过滤网筒过滤祛除,从而获得浓缩纯化的纳米脂肪从鲁尔注射器中抽出即完成脂肪组织的分离提取与浓缩纯化操作。而分离后的液体油滴等废液在活塞的上方透过过滤网筒后下落又从活塞的下方进入到过滤网筒内,并从吸气孔进入到芯杆内,再沿着负压抽吸接口流出,负压抽吸接口底部可以放上废液收集瓶(未示出)对废液进行收集。The utility model protects a device for separating, extracting, concentrating and purifying nano-fat. When it is necessary to separate, extract, concentrate and purify adipose tissue, first install the fat suction tube on the Luer three-way valve, and the top of the fat suction tube enters the For adipose tissue, the Luer three-way valve is in the state where the fat suction tube is connected to the separation and purification tube, and then the negative pressure suction interface is connected to the negative pressure pump and the negative pressure pump works to pump the separation and purification tube into a negative pressure state to make the fat The tissue quickly enters the separation and purification tube from the liposuction tube through the Luer three-way valve. Then the negative pressure pump stops working, and it is separated from the negative pressure suction interface. The Luer syringe 14 and the second Luer syringe 15 are repeatedly flushed through the Luer three-way valve to mechanically emulsify the fat particles, and the resulting liquid oil droplets are filtered and removed through the filter cartridge, so as to obtain concentrated and purified nano-fat from Luer. The separation, extraction, concentration and purification of adipose tissue can be completed by pulling it out from the syringe. The separated liquid oil droplets and other waste liquids pass through the filter screen cylinder above the piston, and then fall into the filter screen cylinder from the bottom of the piston, and enter the core rod from the suction hole, and then pump along the negative pressure. The suction port flows out, and a waste liquid collection bottle (not shown) can be placed on the bottom of the negative pressure suction port to collect the waste liquid.

综上所述,本实用新型提供的一种纳米脂肪的分离提取与浓缩纯化装置,本装置结构简单,体积小,重量轻,操作方便省力,并且可在保留纳米脂肪组织活性的基础上进行高效的分离提取,并通过纯化与浓缩纳米脂肪提高其生物活性,减少其注射引起的不良反应,本装置制备的纳米脂肪具有纯度高、活性好的优势,适用于整形外科、关节外科等医疗领域的应用。In summary, the utility model provides a device for separating, extracting, concentrating and purifying nano-fat. The device is simple in structure, small in size, light in weight, easy to operate and labor-saving, and can perform high-efficiency on the basis of retaining the activity of nano-fat tissue. The separation and extraction of nano-fat can improve its biological activity through purification and concentration, and reduce the adverse reactions caused by its injection. The nano-fat prepared by this device has the advantages of high purity and good activity, and is suitable for plastic surgery, joint surgery and other medical fields. application.

以上所述仅为本实用新型的优选实施例而已,并不用于限制本实用新型,对于本领域的技术人员来说,本实用新型可以有各种更改和变化。凡在本实用新型的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本实用新型的保护范围之内。The above descriptions are only preferred embodiments of the utility model, and are not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.

Claims (7)

1. A separation of nanometer fat is drawed and is concentrated purification device which characterized in that: including fat suction tube, separation purification pipe and negative pressure suction device, the fat suction tube be located separation purification pipe top and with the separation purification between manage through luer three-way valve intercommunication, install the filter screen section of thick bamboo in the separation purification pipe, negative pressure suction device includes core bar, piston and negative pressure suction interface, the core bar stretches into in the filter screen section of thick bamboo from separation purification socle portion, and core bar upper portion has seted up the suction opening, piston fixed mounting is in the core bar top, negative pressure suction interface is located the core bar bottom and stretches out separation purification pipe.
2. The apparatus for separating, extracting, concentrating and purifying nano-fat as claimed in claim 1, wherein the fat suction tube comprises a suction tube body and a suction tube base, the upper portion of the suction tube body is provided with a fat suction hole, the suction tube base comprises a connection tube and a clamping holder, the clamping holder is clamped on the top of the luer three-way valve, and the connection tube fixedly passes through the clamping holder and is communicated with the suction tube body and the luer three-way valve.
3. The apparatus for separating, extracting, concentrating and purifying nano-fat according to claim 1, wherein the separation and purification tube has a collection port at the top and a sealing plate at the bottom, and the luer three-way valve is installed at the collection port of the separation and purification tube.
4. The device for separating, extracting, concentrating and purifying nano-fat according to claim 1, wherein the core rod is fixedly provided with a press hand above the negative pressure suction port.
5. The apparatus for separating, extracting, concentrating and purifying nano-fat according to claim 1, wherein the luer three-way valve is provided with a luer.
6. The device for separating, extracting, concentrating and purifying nano-fat according to claim 1, wherein the negative pressure suction port is a threaded beveled port.
7. The apparatus for separating, extracting, concentrating and purifying nano-fat according to claim 2, wherein the fat suction hole is plural.
CN202221323103.8U 2022-05-30 2022-05-30 A kind of nano fat separation, extraction, concentration and purification device Active CN217709442U (en)

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