CN216222456U - Marrow hemopoietic stem cell collector - Google Patents
Marrow hemopoietic stem cell collector Download PDFInfo
- Publication number
- CN216222456U CN216222456U CN202121634670.0U CN202121634670U CN216222456U CN 216222456 U CN216222456 U CN 216222456U CN 202121634670 U CN202121634670 U CN 202121634670U CN 216222456 U CN216222456 U CN 216222456U
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- China
- Prior art keywords
- hematopoietic stem
- stem cell
- injection
- outside
- marrow hematopoietic
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- Expired - Fee Related
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- 210000003995 blood forming stem cell Anatomy 0.000 title description 2
- 238000002347 injection Methods 0.000 claims abstract description 60
- 239000007924 injection Substances 0.000 claims abstract description 60
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims abstract description 35
- 210000001185 bone marrow Anatomy 0.000 claims abstract description 30
- 238000001914 filtration Methods 0.000 claims abstract description 18
- 238000010070 extrusion (rubber) Methods 0.000 claims description 16
- 238000001125 extrusion Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 abstract description 9
- 238000000605 extraction Methods 0.000 abstract description 2
- 239000008187 granular material Substances 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000007599 discharging Methods 0.000 description 2
- 230000000735 allogeneic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 238000011134 hematopoietic stem cell transplantation Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
Images
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The utility model discloses a bone marrow hematopoietic stem cell collector, which relates to the field of mechanical and medical instruments, and adopts the technical scheme that the collector comprises an injection tube, wherein a filtering mechanism is arranged outside the injection tube, and an injection mechanism is arranged inside the injection tube; filtering mechanism is including installing at the outside No. 12 syringe needles of injection tube, the outside of No. 12 syringe needles is provided with the connecting pipe, the outside of connecting pipe is provided with fixed pipe, the outside of fixed pipe is provided with No. 9 syringe needles, the inside of injection tube is seted up there is the whirl groove, through No. 12 syringe needles, the connecting pipe, the integration to No. 12 syringe needles and No. 9 syringe needles can be realized to the cooperation use of fixed pipe and No. 9 syringe needles, and then realize the double filtration to the large granule material in the marrow hematopoietic stem cell in the exhaust in-process to the marrow hematopoietic stem cell, and is more high-efficient, a large amount of manpowers are saved in extraction that need not relapse, also need the filter screen to filter simultaneously, guarantee the security and the high efficiency that marrow hematopoietic stem cell gathered.
Description
Technical Field
The utility model relates to the technical field of medical treatment, in particular to a bone marrow hematopoietic stem cell collector.
Background
Allogeneic hematopoietic stem cell transplantation is currently an important method for treating malignant hematological diseases. Hematopoietic stem cells may be collected from Bone Marrow (BM) and peripheral blood hematopoietic stem cells (PBSC) of a donor.
Currently, two methods are used clinically for filtration of bone marrow harvest: the first method is to use a special double-layer filter screen to filter bone tissues and fat particles in bone marrow blood through the filter screen; the second type uses a disposable syringe (10ml) to aspirate the bone marrow, first filtering with a 12 gauge needle into another 10ml syringe, then filtering with a 9 gauge needle into a blood bag.
In the traditional bone marrow hematopoietic stem cell collecting process, a filter screen needs to be continuously stirred to prevent the coagulation of bone marrow blood, but the bone marrow blood is easy to be polluted after being exposed in the air for a long time; the steps of sequentially extracting and filtering by using the No. 12 needle and the No. 9 needle are complicated, and the bone marrow blood is easy to splash when the needle is repeatedly turned over, so that a bone marrow hematopoietic stem cell collector is required
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the defect that the filtration is complicated in the process of collecting bone marrow hematopoietic stem cells in the prior art, and provides a bone marrow hematopoietic stem cell collector.
In order to achieve the purpose, the utility model adopts the following technical scheme:
the bone marrow hematopoietic stem cell collector comprises an injection cylinder, wherein a filtering mechanism is arranged outside the injection cylinder, and an injection mechanism is arranged inside the injection cylinder;
the filtering mechanism is including installing injection cylinder outside 12 syringe needles, the outside of 12 syringe needles is provided with the connecting pipe, the outside of connecting pipe is provided with fixed pipe, the outside of fixed pipe is provided with 9 syringe needles, the inside of injection cylinder is seted up there is the whirl groove.
The above technical solution further comprises:
the outside of injection tube is provided with the injection head, the injection head with the inside of 12 syringe needles closely laminates, the internally mounted of connecting pipe has rubber extrusion piece a, 12 syringe needles run through to the inside of connecting pipe, 12 syringe needles with the outside of rubber extrusion piece a closely laminates.
The inside mounting of fixed pipe has rubber extrusion block b, the connecting pipe is kept away from the one end of 12 # syringe needles runs through extremely the inside of fixed pipe, the connecting pipe with the outside of rubber extrusion block b closely laminates.
The fixed tube is tightly attached to the inside of the 9-gauge needle head.
The injection head is communicated with the interior of the injection tube, the interior of the injection tube is movably connected with a piston, an extrusion rod is arranged outside the piston, and an extrusion plate is arranged at one end, far away from the piston, of the extrusion rod.
The piston is tightly attached to the periphery of the interior of the injection tube, and the pressing plates are symmetrically arranged on the exterior of the injection tube.
Compared with the prior art, the utility model has the beneficial effects that:
according to the utility model, the 12-needle head and the 9-needle head can be integrated by matching the 12-needle head, the connecting pipe, the fixing pipe and the 9-needle head, so that the double filtration of large granular substances in the bone marrow hematopoietic stem cells is realized in the process of discharging the bone marrow hematopoietic stem cells, the efficiency is higher, a large amount of manpower is saved without repeated extraction, and meanwhile, a filter screen is not required for filtration, so that the safety and the efficiency of collecting the bone marrow hematopoietic stem cells are ensured.
In the utility model, the marrow hematopoietic stem cells discharged from the injection tube can be in a rotational flow shape through the rotational flow groove, so that large granular substances accumulated outside the injection head can move towards the periphery, and the collection efficiency of the marrow hematopoietic stem cells is improved.
Drawings
FIG. 1 is a schematic perspective view of a bone marrow hematopoietic stem cell collector according to the present invention;
FIG. 2 is a schematic view of the internal structure of the present invention;
FIG. 3 is a perspective view of the filter mechanism of the present invention;
FIG. 4 is a schematic view of the internal structure of the filter mechanism of the present invention;
FIG. 5 is an enlarged view of the structure at A in FIG. 3;
fig. 6 is an enlarged view of the structure at B in fig. 3.
In the figure: 1. an injection tube; 2. a piston; 3. a swirling flow groove; 4. an extrusion stem; 5. a pressing plate; 6. an injection head; 7. a needle head of No. 12; 8. a connecting pipe; 9. a fixed tube; 10. a 9 gauge needle; 11. a rubber extrusion block a; 12. a rubber extrusion block b; 13. and (5) pressing the plate.
Detailed Description
The technical solution of the present invention is further explained with reference to the accompanying drawings and specific embodiments.
Example one
As shown in the injection barrels 1-6, the electric bicycle motor detection device of the bone marrow hematopoietic stem cell collector comprises an injection barrel 1, wherein a filtering mechanism is arranged outside the injection barrel 1;
filtering mechanism is including installing No. 12 syringe needles 7 in injection tube 1 outside, the outside of No. 12 syringe needles 7 is provided with connecting pipe 8, the outside of connecting pipe 8 is provided with fixed pipe 9, the outside of fixed pipe 9 is provided with No. 9 syringe needles 10, whirl groove 3 has been seted up to the inside of injection tube 1, the outside of injection tube 1 is provided with injection head 6, the inside of injection head 6 and No. 12 syringe needles 7 closely laminates, the internally mounted of connecting pipe 8 has rubber extrusion piece a11, No. 12 syringe needles 7 run through to the inside of connecting pipe 8, No. 12 syringe needles 7 closely laminate with the outside of rubber extrusion piece a11 and, the internally mounted of fixed pipe 9 has rubber extrusion piece b12, the one end that No. 12 syringe needles 7 were kept away from to connecting pipe 8 runs through to the inside of fixed pipe 9, the outside of connecting pipe 8 and rubber extrusion piece b12 closely laminates, the inside of fixed pipe 9 and No. 9 syringe needles 10 closely laminates.
The bone marrow hematopoietic stem cell collector based on the first embodiment has the working principle that when in use, the needle head part of the needle head 7 of No. 12 is inserted into the connecting pipe 8, at the moment, the rubber extrusion block a11 can be propped against the outside of the needle head 7 of No. 12 to fix the needle head 7 of No. 12, then the needle head is plugged into the fixed pipe 9, at the moment, the elasticity of the rubber extrusion block b12 can fix the connecting pipe 8, finally, the needle head 10 of No. 9 is sleeved at the end part of the fixed pipe 9, so that the needle head 7 of No. 12 and the needle head 10 of No. 9 are integrated, in the process of discharging bone marrow hematopoietic stem cells, the bone marrow hematopoietic stem cells sequentially pass through the needle head 7 of No. 12, the connecting pipe 8, the fixed pipe 9 and the needle head 10 of No. 9 under the external pressure, then are discharged into a bone marrow bag through the needle head 10 of No. 9, and the needle heads 7 of No. 12 and 10 can filter residual large granular substances in the bone marrow hematopoietic stem cells, the secondary filtration of the marrow hematopoietic stem cells is realized, the filtration efficiency of the marrow hematopoietic stem cells is increased, and meanwhile, the No. 12 needle 7 and the No. 9 needle 10 can also be directly connected through a specially customized pipeline.
Example two
As shown in fig. 1-2, based on the first embodiment, an injection mechanism is disposed inside an injection tube 1, an injection head 6 is communicated with the inside of the injection tube 1, a piston 2 is movably connected inside the injection tube 1, an extrusion rod 4 is disposed outside the piston 2, an extrusion plate 13 is disposed at one end of the extrusion rod 4 far away from the piston 2, the piston 2 is tightly attached to the periphery of the inside of the injection tube 1, and pressing plates 5 are symmetrically disposed outside the injection tube 1.
Design like this in the embodiment, during the use, earlier inhale marrow hematopoietic stem cell into the inside of injection tube 1 through injection head 6, then cup joint 12 # syringe needle 7 to the top of injection head 6, press stripper plate 13 through the staff, injection tube 1 drives 4 downstream of stripper rod, stripper rod 4 drives piston 2 downstream, thereby discharge 1 inside marrow hematopoietic stem cell of injection tube through injection head 6, because whirl groove 3 is the heliciform, thereby at extruded process, make 1 inside marrow hematopoietic stem cell of injection tube be the whirl, and then make and pile up the outside large granular material of injection head 6 and move around towards, avoid blockking up injection head 6, the collection efficiency to marrow hematopoietic stem cell has been increased.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.
Claims (6)
1. The marrow hematopoietic stem cell collector comprises an injection tube (1), and is characterized in that a filtering mechanism is arranged outside the injection tube (1), and an injection mechanism is arranged inside the injection tube (1);
the filtering mechanism comprises a No. 12 needle (7) arranged outside the injection cylinder (1), a connecting pipe (8) is arranged outside the No. 12 needle (7), a fixed pipe (9) is arranged outside the connecting pipe (8), a No. 9 needle (10) is arranged outside the fixed pipe (9), and a swirl groove (3) is formed in the injection cylinder (1).
2. The bone marrow hematopoietic stem cell collector according to claim 1, wherein an injection head (6) is arranged outside the injection cylinder (1), the injection head (6) is closely attached to the inside of the 12-gauge needle (7), a rubber extrusion block a (11) is arranged inside the connecting pipe (8), the 12-gauge needle (7) penetrates into the connecting pipe (8), and the 12-gauge needle (7) is closely attached to the outside of the rubber extrusion block a (11).
3. The bone marrow hematopoietic stem cell collector of claim 1, characterized in that a rubber extrusion block b (12) is installed inside the fixed tube (9), one end of the connecting tube (8) far away from the 12-gauge needle (7) penetrates into the fixed tube (9), and the connecting tube (8) is tightly attached to the outside of the rubber extrusion block b (12).
4. The bone marrow hematopoietic stem cell collector of claim 1, wherein the fixing tube (9) is closely attached to the inside of the 9-gauge needle (10).
5. The bone marrow hematopoietic stem cell collector according to claim 2, characterized in that the injection head (6) is communicated with the interior of the injection cylinder (1), the interior of the injection cylinder (1) is movably connected with a piston (2), an extrusion rod (4) is arranged outside the piston (2), and an extrusion plate (13) is arranged at one end of the extrusion rod (4) far away from the piston (2).
6. The bone marrow hematopoietic stem cell collector of claim 5, characterized in that the piston (2) is closely attached to the inner periphery of the syringe (1), and the pressing plate (5) is symmetrically arranged on the outer part of the syringe (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121634670.0U CN216222456U (en) | 2021-07-19 | 2021-07-19 | Marrow hemopoietic stem cell collector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121634670.0U CN216222456U (en) | 2021-07-19 | 2021-07-19 | Marrow hemopoietic stem cell collector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216222456U true CN216222456U (en) | 2022-04-08 |
Family
ID=80980621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121634670.0U Expired - Fee Related CN216222456U (en) | 2021-07-19 | 2021-07-19 | Marrow hemopoietic stem cell collector |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216222456U (en) |
-
2021
- 2021-07-19 CN CN202121634670.0U patent/CN216222456U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220408 |