CN217483971U - Full-automatic cell chromosome karyotype analysis slide preparation equipment - Google Patents
Full-automatic cell chromosome karyotype analysis slide preparation equipment Download PDFInfo
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- CN217483971U CN217483971U CN202221191027.XU CN202221191027U CN217483971U CN 217483971 U CN217483971 U CN 217483971U CN 202221191027 U CN202221191027 U CN 202221191027U CN 217483971 U CN217483971 U CN 217483971U
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Abstract
The utility model discloses a full-automatic cell chromosome karyotype analysis slide glass preparation equipment, including workstation, moving mechanism, inhale the piece head, atomizer, dropping liquid pipe and move a kind rifle, install the first Z axle slide and the second Z axle slide that can reciprocate on moving mechanism, both are connected with the motor respectively in order to realize independently removing, inhale the piece head, atomizer and dropping liquid pipe and install on first Z axle slide together, move a kind rifle and independently install on second Z axle slide. The utility model discloses a sign indicating number camera is swept to an axle control, inhale the film head, atomizer and dropping liquid pipe sweep the sign indicating number respectively, inhale the film and pendulum piece, ultrasonic atomization and drip stationary liquid, move the appearance rifle through another axle control and take a sample and drip the appearance, not only can simplify equipment structure, improve compact structure nature, can make the wet piece of atomizing moreover, drip stationary liquid and drip the operation of sample and link up inseparabler to can accelerate the dispersion velocity of sample and improve the degree of consistency, and improve the efficiency of slide glass preparation.
Description
Technical Field
The utility model relates to a trace sample technical field, concretely relates to cell chromosome karyotype analysis slide glass preparation equipment.
Background
Karyotyping of cell chromosomes is an important means for modern medical genetics research and clinical examination, and the cell chromosomes are uniformly and clearly displayed on a glass slide in a dripping mode, so that people can observe and identify differences of chromosome karyotypes through a microscope, and the preparation of the cell chromosome karyotyping glass slide is the basis for realizing the technology. The preparation of the cell chromosome karyotype analysis slide is generally carried out in a controllable constant temperature and humidity environment, for example, the temperature is generally 10-50 ℃, the humidity is generally 10% -90%, and the preparation method generally comprises the following steps of firstly arranging the slide, then dripping a fixing solution on the slide, then dripping a sample on the fixing solution, and completing the preparation when the sample is uniformly dispersed. In order to improve the dispersion speed and uniformity of the sample, people can carry out ultrasonic atomization on the slide glass to wet the slide glass before dripping the fixative. However, the existing equipment generally adopts a dispersive structure, namely, the sheet suction head, the atomizing spray head, the dropping liquid pipe and the sample moving gun are respectively and independently controlled and independently operated, so that the equipment structure is more complicated and not compact, the connection of the preparation process is not tight enough, the efficiency is lower, and the sample is not uniformly dispersed.
SUMMERY OF THE UTILITY MODEL
The utility model discloses to the shortcoming that prior art exists, provide a simple structure compactness, degree of automation height, preparation efficiency are higher, sample dispersion speed is faster, the higher full-automatic cell chromosome karyotype analysis slide glass preparation equipment of degree of consistency.
In order to solve the technical problem, the utility model adopts the following technical scheme: the utility model provides a full-automatic cell chromosome karyotype analysis slide glass preparation equipment, is including workstation, moving mechanism, inhale the slide head, atomizer, dropping liquid pipe and move a kind rifle (or refer to and move a kind pipe etc.), and moving mechanism installs on the workstation, and the slide glass puts on the workstation through the slide rack, inhales the slide head and is connected with evacuating device, and the dropping liquid pipe is connected with the reservoir (stores stationary liquid such as methyl alcohol and acetic acid mixed liquid), its characterized in that: install first Z axle slide and second Z axle slide that can reciprocate on moving mechanism, both are connected with the motor respectively in order to realize independently moving, inhale piece head, atomizer and dropping liquid pipe and install together on first Z axle slide in order to form the structure that can do synchronous motion, move a kind rifle and independently install in order to form the structure that can do independently moving on the second Z axle slide.
Furthermore, the moving mechanism comprises an X-axis mechanism and a Y-axis mechanism, a pair of Y-axis mechanisms are arranged on the workbench, and the X-axis mechanism is arranged on the Y-axis mechanism in a spanning mode to form a structure capable of moving along the Y-axis direction; an X-axis sliding seat capable of moving along the X-axis direction is arranged on the X-axis mechanism, a first vertical guide rail and a second vertical guide rail are arranged on the X-axis sliding seat, and a first Z-axis sliding seat and a second Z-axis sliding seat are respectively erected on the first guide rail and the second guide rail.
Furthermore, two motors are installed on the X-axis sliding seat through a motor box, the first Z-axis sliding seat is connected with one of the motors through a first synchronous belt, and the second Z-axis sliding seat is connected with the other motor through a second synchronous belt, so that the first Z-axis sliding seat and the second Z-axis sliding seat can move along the Z-axis direction respectively.
Furthermore, the scanning camera is arranged on the side surface of the X-axis sliding seat and close to the suction head, and the two-dimensional code on each glass slide is read through the scanning camera.
Further, a slide box is arranged on the workbench, and the slide box is close to the position for placing the slide rack and is positioned below the X-axis sliding seat. After the operation is started, the glass slides are sucked from the glass slide box through the glass suction head and placed on the glass slide rack one by one.
Furthermore, a sample rack and a pipette rack are arranged on the workbench, the sample rack and the pipette rack are arranged beside the glass rack side by side, the sample moving stroke can be reduced, the time is saved, a sample tube is placed through the sample rack, and a pipette is placed through the pipette rack.
Furthermore, each sample tube is provided with a two-dimensional code, each glass slide is also provided with a two-dimensional code, and the two-dimensional codes on the glass slides correspond to the two-dimensional codes on the sample tubes one by one. After sweeping the sign indicating number through sweeping the two-dimensional code of sign indicating number camera to each slide, the system can be automatic to correspond with the sample cell on the sample frame, and follow-up meeting control moves a appearance rifle and seeks corresponding sample cell automatically and take a sample to improve accuracy and efficiency.
Furthermore, a collecting box for collecting used straws is further arranged on the workbench, the collecting box is close to the straw rack and located below the second Z-axis sliding seat, and therefore the sample moving gun can clamp the next straw more quickly after discarding the used straw, the stroke can be reduced, and time can be saved.
Furthermore, the bottom end of the liquid dropping pipe is basically flush with the bottom end of the atomizing spray head, and the bottom end of the sheet suction head is lower than the bottom end of the atomizing spray head, so that the atomizing spray head and the liquid dropping pipe cannot touch the glass slide when the sheet suction head sucks the glass slide and puts down the glass slide.
The utility model discloses a sign indicating number camera is swept to a control, inhale the piece head, atomizer and dropping liquid pipe sweep the sign indicating number respectively, inhale the piece and pendulum the piece, ultrasonic atomization and drip the stationary liquid, move a kind rifle through another axle control and take a sample and drip appearance, so not only can simplify the structure of equipment, improve compact structure nature, and can make the wet piece of atomizing moreover, drip stationary liquid and drip the operation of sample and link up inseparabler, thereby can accelerate the dispersion velocity and the improvement degree of consistency of sample, and improve the efficiency of slide glass preparation. Meanwhile, manual swing is replaced by automatic swing of the suction head, so that the efficiency can be greatly improved.
Drawings
FIG. 1 is a view of the overall structure of the present invention;
FIG. 2 is an enlarged view of a portion of FIG. 1;
FIG. 3 is a front view of the present invention;
fig. 4 is a top view of the present invention.
In the figure, 1 is a workbench, 2 is a Y-axis mechanism, 3 is an X-axis mechanism, 4 is an X-axis slide, 5 is a first Z-axis slide, 6 is a code scanning camera, 7 is a film suction head, 8 is an atomizing nozzle, 9 is a dropping liquid pipe, 10 is a first guide rail, 11 is a first synchronous belt, 12 is a second guide rail, 13 is a second synchronous belt, 14 is a second Z-axis slide, 15 is a sample moving gun, 16 is a motor box, 17 is a liquid storage device, 18 is a slide rack, 19 is a slide glass, 20 is a slide box, 21 is a sample rack, 22 is a sample pipe, 23 is a suction pipe rack, 24 is a suction pipe, and 25 is a collection box.
Detailed Description
In the embodiment, referring to fig. 1-4, the full-automatic cell chromosome karyotype analysis slide glass preparation apparatus includes a workbench 1, a moving mechanism, a slide sucking head 7, an atomizing nozzle 8, a dropping liquid tube 9 and a sample moving gun 15, wherein the moving mechanism is installed on the workbench 1, a slide 19 is placed on the workbench 1 through a slide rack 18, the slide sucking head 7 is connected with a vacuum extractor to realize vacuum suction, the atomizing nozzle 8 is connected with a water supply mechanism to realize ultrasonic atomization, and the dropping liquid tube 9 is connected with a liquid reservoir 17; the moving mechanism is provided with a first Z-axis sliding seat 5 and a second Z-axis sliding seat 14 which can move up and down, the first Z-axis sliding seat 5 and the second Z-axis sliding seat 14 are respectively connected with a motor to realize independent movement, the sheet suction head 7, the atomizing nozzle 8 and the dropping liquid pipe 9 are arranged on the first Z-axis sliding seat 5 together to form a structure capable of moving synchronously, and the sample moving gun 15 is arranged on the second Z-axis sliding seat 14 independently to form a structure capable of moving independently.
The moving mechanism comprises an X-axis mechanism 3 and a Y-axis mechanism 2, a pair of Y-axis mechanisms 2 are arranged on the workbench 1, and the X-axis mechanism 3 is arranged on the Y-axis mechanisms 2 in a spanning mode to form a structure capable of moving along the Y-axis direction; an X-axis sliding base 4 capable of moving along the X-axis direction is arranged on the X-axis mechanism 3, a first vertical guide rail 10 and a second vertical guide rail 12 are arranged on the X-axis sliding base 4, and a first Z-axis sliding base 5 and a second Z-axis sliding base 14 are respectively erected on the first guide rail 10 and the second guide rail 12.
Two motors are arranged on the X-axis sliding base 4 through a motor box 16, the first Z-axis sliding base 4 is connected with one motor through a first synchronous belt 11, and the second Z-axis sliding base 14 is connected with the other motor through a second synchronous belt 13, so that the first Z-axis sliding base 5 and the second Z-axis sliding base 14 can respectively move along the Z-axis direction.
A scanning camera 6 is also included, the scanning camera 6 is arranged on the side surface of the X-axis sliding seat 4 and close to the suction head 7, and the two-dimensional code on each glass slide 19 is read through the scanning camera 6.
On the table 1 is arranged a slide magazine 20, which slide magazine 20 is located close to the position for placing the slide racks 18 and below the X-axis slide 4. The operation begins by first sucking slides 19 from the slide magazine 20 by the suction head 7 and placing them one by one on the slide racks 18, each rack 18 being able to hold 64 slides 19.
The sample rack 21 and the pipette rack 23 are arranged on the workbench 1, the sample rack 21 and the pipette rack 23 are arranged beside the slide rack 18 in parallel, so that the sample moving stroke can be reduced, the time is saved, the sample tube 22 is placed through the sample rack 21, and the pipette 24 is placed through the pipette rack 23.
Each sample tube 22 is provided with a two-dimensional code, each glass slide 19 is also provided with a two-dimensional code, and the two-dimensional codes on the glass slides 19 correspond to the two-dimensional codes on the sample tubes 22 one by one. After the two-dimensional code of each glass slide 19 is scanned by the code scanning camera 6, the system can automatically correspond to the sample tube 22 on the sample rack 21, and the sample moving gun 15 is controlled to automatically find the corresponding sample tube 22 for sampling, so that the accuracy and the efficiency are improved.
A collection box 25 for collecting used pipettes 24 is also arranged on the workbench 1, and the collection box 25 is close to the pipette rack 23 and is positioned below the second Z-axis slide carriage 14, so that the sample removing gun 15 can more quickly clamp a next pipette 24 after discarding the used pipette 24, the stroke can be reduced, and the time can be saved.
The bottom end of the dropping liquid tube 9 is basically flush with the bottom end of the atomizing nozzle 8, and the bottom end of the piece sucking head 7 is lower than the bottom end of the atomizing nozzle 8, so that the piece sucking head 7 can not touch the glass slide 19 by the atomizing nozzle 8 and the dropping liquid tube 9 when sucking the glass slide 19 and putting down the glass slide 19.
The equipment work flow is as follows: the sample tube 22 is manually scanned, the chip suction head 7 automatically takes and puts chips, the camera 6 is scanned automatically to scan chips, the atomizing nozzle 8 carries out ultrasonic atomization to wet chips, the dropping liquid tube 9 drops fixing liquid, and the sample moving gun 15 carries out sampling and dropping samples.
The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the scope of the invention, i.e. the present invention is intended to cover all equivalent variations and modifications within the scope of the present invention.
Claims (9)
1. The utility model provides a full-automatic cell chromosome karyotype analysis slide glass preparation equipment, is including workstation, moving mechanism, inhale the film head, atomizer, dropping liquid pipe and move a kind rifle, and moving mechanism installs on the workstation, and the slide glass puts on the workstation through the slide frame, inhales the film head and is connected with evacuating device, and the dropping liquid pipe is connected with reservoir, its characterized in that: install first Z axle slide and second Z axle slide that can reciprocate on moving mechanism, both are connected with the motor respectively in order to realize independently moving, inhale piece head, atomizer and dropping liquid pipe and install together on first Z axle slide in order to form the structure that can do synchronous motion, move a kind rifle and independently install in order to form the structure that can do independently moving on the second Z axle slide.
2. The fully automated cytokaryotyping slide preparation apparatus according to claim 1, wherein: the moving mechanism comprises an X-axis mechanism and a Y-axis mechanism, a pair of Y-axis mechanisms are arranged on the workbench, and the X-axis mechanism is arranged on the Y-axis mechanism in a spanning mode to form a structure capable of moving along the Y-axis direction; an X-axis sliding seat capable of moving along the X-axis direction is arranged on the X-axis mechanism, a first vertical guide rail and a second vertical guide rail are arranged on the X-axis sliding seat, and a first Z-axis sliding seat and a second Z-axis sliding seat are respectively erected on the first guide rail and the second guide rail.
3. The fully automated cytokaryotyping slide preparation apparatus according to claim 2, wherein: two motors are installed on the X-axis sliding seat through a motor box, the first Z-axis sliding seat is connected with one of the motors through a first synchronous belt, and the second Z-axis sliding seat is connected with the other motor through a second synchronous belt, so that the first Z-axis sliding seat and the second Z-axis sliding seat can move along the Z-axis direction respectively.
4. The fully automated cytokaryotyping slide preparation apparatus according to claim 2, wherein: the X-axis slide carriage is characterized by further comprising a code scanning camera, wherein the code scanning camera is installed on the side face of the X-axis slide carriage and is close to the suction piece head.
5. The fully automated cytokaryotyping slide preparation apparatus according to claim 2, wherein: the slide box is arranged on the workbench, is close to the position for placing the slide rack and is positioned below the X-axis slide seat.
6. The fully automated cytokaryotyping slide preparation apparatus according to claim 4, wherein: the sample rack and the pipette rack are arranged on the workbench and are arranged beside the slide rack in parallel, the sample tube is placed through the sample rack, and the pipette is placed through the pipette rack.
7. The fully automated cytokaryotyping slide preparation apparatus according to claim 6, wherein: each sample tube is provided with a two-dimensional code, each glass slide is also provided with a two-dimensional code, and the two-dimensional codes on the glass slides correspond to the two-dimensional codes on the sample tubes one by one.
8. The fully automated cytological karyotyping slide preparation apparatus of claim 6, wherein: and a collecting box for collecting used straws is also arranged on the workbench, and the collecting box is close to the straw rack and is positioned below the second Z-axis sliding seat.
9. The fully automated cytological karyotyping slide preparation apparatus of claim 1, wherein: the bottom end of the dropping liquid pipe is basically flush with the bottom end of the atomizing spray head, and the bottom end of the sheet sucking head is lower than the bottom end of the atomizing spray head.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221191027.XU CN217483971U (en) | 2022-05-18 | 2022-05-18 | Full-automatic cell chromosome karyotype analysis slide preparation equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221191027.XU CN217483971U (en) | 2022-05-18 | 2022-05-18 | Full-automatic cell chromosome karyotype analysis slide preparation equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217483971U true CN217483971U (en) | 2022-09-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221191027.XU Active CN217483971U (en) | 2022-05-18 | 2022-05-18 | Full-automatic cell chromosome karyotype analysis slide preparation equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217483971U (en) |
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2022
- 2022-05-18 CN CN202221191027.XU patent/CN217483971U/en active Active
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