CN217278397U - Full-automatic analytical equipment is used in small-size ELISA adsorption test - Google Patents

Full-automatic analytical equipment is used in small-size ELISA adsorption test Download PDF

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Publication number
CN217278397U
CN217278397U CN202220303290.7U CN202220303290U CN217278397U CN 217278397 U CN217278397 U CN 217278397U CN 202220303290 U CN202220303290 U CN 202220303290U CN 217278397 U CN217278397 U CN 217278397U
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full
square
axis slide
console
motor
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CN202220303290.7U
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李周敏
张丹丹
李帷帷
汤迪朋
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Jiangsu Xiangzhong Technology Co ltd
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Nanjing Xiangzhong Biotechnology Co ltd
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Abstract

The utility model provides a full-automatic analytical equipment is used in small-size ELISA adsorption test. Full-automatic analysis device for small-size enzyme-linked immunosorbent assay is including setting up the full-automatic analysis equipment in square safety cover, the bottom of square safety cover is equipped with the opening, full-automatic analysis equipment is including controlling the platform, it contacts with square safety cover to control the platform, the top of controlling the platform is equipped with back type frame, be equipped with motor one and motor two on the back type frame, the top fixed mounting who controls the platform has Contraband types to place the platform, Contraband types are placed the bench and are connected with the collection box. The utility model provides a full automatic analysis device is used in small-size ELISA adsorption test has convenient to use, can simply effectually realize upper and lower, left and right removal at the in-process of experiment, can accomplish full-automatic application of sample, and the reaction washs and detects etc. and simple convenient advantage is got up in the operation.

Description

Full-automatic analytical equipment is used in small-size ELISA adsorption test
Technical Field
The utility model belongs to the technical field of the analysis and detection, especially, relate to a full automatic analysis device is used in small-size ELISA adsorption test.
Background
Enzyme linked immunosorbent assay (ELISA) or microarray biochip is used as a method for measuring trace antigen and antibody, and is widely applied to food safety detection, clinical measurement and scientific research experiments due to high sensitivity, high specificity and low cost;
in the related technology, a dipterex bionic enzyme-linked immunosorbent assay method is disclosed, a dipterex molecularly imprinted polymer membrane is used as an artificial antibody to replace a biological antibody, and the bionic enzyme-linked immunosorbent assay method with high sensitivity to dipterex is established by utilizing the enzyme-linked immunosorbent assay principle, wherein the lowest detection limit of the method is 7 mu gL-1, which is greatly lower than the highest residual limit value, and the analysis time is greatly shortened (1.0 h shorter than the traditional biological immunoassay), so that the method is suitable for rapidly detecting dipterex, the prepared bionic antibody can be reused for more than 50 times, and the cost is greatly reduced; and the method has the advantages of simple pretreatment, high sensitivity and simple experimental operation, and is suitable for rapid detection of trichlorfon in various foods.
However, the above structure has disadvantages, and the omission, addition or wrong addition is easy to occur during the ELISA test process in the above structure, thereby affecting the test result.
Therefore, it is necessary to provide a new small-sized full-automatic analyzer for enzyme-linked immunosorbent assay to solve the above-mentioned problems.
SUMMERY OF THE UTILITY MODEL
The technical problem solved by the utility model is to provide a convenient to use, can simply effectually realize upper and lower, left and right removal at the in-process of experiment, can accomplish full-automatic application of sample, reaction, washing and detection etc. operate simple convenient small-size ELISA adsorption test and use full-automatic analytical equipment.
In order to solve the technical problem, the utility model provides a full-automatic analytical equipment for small-size ELISA adsorption test includes the full-automatic analytical equipment who sets up in square safety cover, the bottom of square safety cover is equipped with the opening, full-automatic analytical equipment is including the control platform, the control platform contacts with square safety cover, install the CCD camera in the square safety cover the top of control platform is equipped with back type frame, be equipped with motor one and motor two on the back type frame, the top of control platform is fixed and is installed Contraband type platform, Contraband type platform is connected with collection box, two case, reaction liquid-transfering machine group and formation of image detection unit, be equipped with lateral shifting mechanism and longitudinal movement mechanism on the control platform;
the transverse moving mechanism comprises a motor III, the motor III is fixedly installed at the top of the console, a transverse screw is fixedly installed on an output shaft of the motor III, two X-axis slide rails are fixedly installed at the top of the console, an X-axis slide rail is installed on the X-axis slide rails in a sliding mode, the top of the X-axis slide rail is fixedly connected with the clip-shaped frame, and one end, far away from the motor III, of the transverse screw is installed on the clip-shaped frame in a threaded mode;
the vertical moving mechanism comprises a pipettor installation unit, the pipettor installation unit is slidably installed on the clip frame, a plurality of pipette heads are arranged on the pipettor installation unit and located below the pipettor installation unit, a plurality of vertical connecting rods are arranged on the pipettor installation unit and adapted to the corresponding pipette heads, a transverse connecting plate is arranged above the pipettor installation unit and slidably installed on the clip frame, a plurality of convex columns are fixedly installed at the bottom of the transverse connecting plate, and the top ends of the vertical connecting rods are fixedly connected with the corresponding convex columns.
As a further scheme of the utility model, fixed mounting has longitudinal screw on the output shaft of motor one, the thread bush is equipped with internal thread sleeve one on the longitudinal screw one, one side and the transverse connection board fixed connection that transverse connection board is close to internal thread sleeve one, fixed mounting has longitudinal screw two on the output shaft of motor two, the thread bush is equipped with internal thread sleeve two on the output shaft of longitudinal screw two, one side and pipettor installation unit fixed connection that internal thread sleeve two is close to pipettor installation unit.
As a further scheme of the utility model, equal fixed mounting has Y axle slide rail on the both sides inner wall of time type frame, slidable mounting has Y axle slide on the Y axle slide rail, the both sides of pipettor installation unit respectively with two Y axle slide fixed connection.
As a further scheme of the utility model, set up threaded hole on the type frame returns, screw hole and horizontal screw rod threaded connection, the bottom fixed mounting who controls the platform has four supporting legs.
As a further scheme of the utility model, be equipped with square cabinet door on the square safety cover, square cabinet door passes through the hinge with square safety cover and articulates, fixed mounting has the door handle on the square cabinet door, be equipped with liquid crystal display and shift knob on the square safety cover.
Compared with the prior art, the utility model provides a full-automatic analytical equipment is used in small-size ELISA adsorption test has following beneficial effect:
1. the utility model discloses a set up the lateral shifting mechanism, the lateral shifting mechanism can simply effectually realize moving about in the ELISA adsorption test's process, can adjust the position of liquid-transfering gun head as required, realize application of sample and move liquid operation, avoid makeing mistakes;
2. the utility model discloses a set up longitudinal movement mechanism, longitudinal movement mechanism can simply effectual upper and lower position of removal liquid-transfering gun head, also can dismantle it as required, and convenient to use person operates.
3. The utility model discloses a CCD camera and liquid crystal display mutually support, can reach the imaging data processing effect, realize the reaction and the quantitative determination of the sample that awaits measuring then.
Drawings
In order to facilitate understanding for those skilled in the art, the present invention will be further described with reference to the accompanying drawings.
FIG. 1 is a schematic perspective view of a preferred embodiment of a small-sized full-automatic analyzer for ELISA according to the present invention;
FIG. 2 is a front sectional view of the present invention;
FIG. 3 is a schematic perspective view of a fully automatic analyzer of the present invention;
FIG. 4 is an enlarged schematic view of portion A of FIG. 3;
fig. 5 is a schematic left-view structural diagram of the central full-automatic analysis device of the present invention;
fig. 6 is a combined schematic view of a front view, a left side view and a right side view of the present invention;
fig. 7 is a schematic view of the top view of the square protective cover and the top view structure of the full-automatic analysis device of the present invention.
In the figure: 1. a square protective cover; 101. a square cabinet door; 102. a door handle; 103. a liquid crystal display screen; 104. a switch button; 2. a fully automatic analytical device; 201. a console; 202. a clip frame; 203. a first motor; 2031. a first longitudinal screw; 2032. a first internal thread sleeve; 204. A second motor; 2041. a second longitudinal screw; 2042. a second internal thread sleeve; 205. model Contraband placement table; 206. a collection box; 207. a storage box; 208. a reaction pipetting unit; 209. an imaging detection unit; 3. a third motor; 301. a transverse screw; 302. an X-axis slide rail; 303. an X-axis slide; 4. a pipettor mounting unit; 401. a pipette tip; 402. a vertical type connecting rod; 403. A transverse connecting plate; 404. a convex column.
Detailed Description
Please refer to fig. 1 to 7, wherein fig. 1 is a schematic perspective view of a preferred embodiment of a small-sized full-automatic analyzer for elisa according to the present invention; FIG. 2 is a front sectional view of the present invention; FIG. 3 is a schematic perspective view of a fully automatic analyzer of the present invention; FIG. 4 is an enlarged schematic view of portion A of FIG. 3; fig. 5 is a left side view schematic diagram of the full-automatic analyzer of the present invention; fig. 6 is a combined schematic view of a front view, a left side view and a right side view of the present invention; fig. 7 is a schematic top view of the square protective cover and a schematic top view structure of the fully automatic analysis device of the present invention. The full-automatic analysis device for the small enzyme-linked immunosorbent assay comprises a full-automatic analysis device 2 arranged in a square protective cover 1, a CCD camera is arranged in the square protective cover 1, is electrically connected with the liquid crystal display screen 103 through a lead, the bottom of the square protective cover 1 is provided with an opening, the full-automatic analysis device 2 comprises a control platform 201, the control platform 201 is contacted with the square protection cover 1, a first motor 203 and a second motor 204 are arranged on the rectangular frame 202, the top of the console 201 is fixedly provided with an Contraband type placing table 205, the Contraband type placing table 205 is connected with a collecting box 206, the collecting box 206 is used for storing waste pipette tips 401, two storing boxes 207, a reaction pipette unit 208 and an imaging detection unit 209, and a transverse moving mechanism and a longitudinal moving mechanism are arranged on the console 201;
the reaction pipetting unit 208 can adopt a 96-well elisa plate, the content of the 96-well elisa plate can be distributed in a rectangular array or not according to the array form, and the bottom of the 96-well elisa plate is provided with heating equipment for heating in the reaction process with the reagent to provide the temperature required by the reaction;
a light-emitting back plate is arranged below the imaging detection unit 209, and mainly photographs through a CCD (charge coupled device) to obtain images, and then a software extracts signals and provides a detection report;
the transverse moving mechanism comprises a motor III 3, the motor III 3 is fixedly installed at the top of the console 201, a transverse screw 301 is fixedly installed on an output shaft of the motor III 3, two X-axis slide rails 302 are fixedly installed at the top of the console 201, an X-axis slide rail 303 is installed on the X-axis slide rails 302 in a sliding manner, the top of the X-axis slide rail 303 is fixedly connected with the clip-shaped frame 202, and one end, far away from the motor III 3, of the transverse screw 301 is installed on the clip-shaped frame 202 in a threaded manner;
when an enzyme-linked immunosorbent assay is required, after corresponding steps are completely prepared, when a liquid dropping moving process is required, the motor III 3 is directly started, an output shaft of the motor III 3 drives the transverse screw 301 to rotate, the transverse screw 301 drives the clip-shaped frame 202 to move under the action of the threads, and under the combined action of the X-axis slide rail 302 and the X-axis slide rail 303, the transverse screw 301 can drive the clip-shaped frame 202 to move left and right;
the longitudinal movement mechanism comprises a pipettor installation unit 4, the pipettor installation unit 4 can be installed and used for 8-channel pipettors, the pipettor installation unit 4 is slidably installed on the clip frame 202, a plurality of pipette tips 401 are arranged on the pipettor installation unit 4, the pipette tips 401 are located below the pipettor installation unit 4, a plurality of vertical connecting rods 402 are arranged on the pipettor installation unit 4, the vertical connecting rods 402 are matched with the corresponding pipette tips 401, a transverse connecting plate 403 is arranged above the pipettor installation unit 4, the transverse connecting plate 403 is slidably installed on the clip frame 202, a plurality of convex columns 404 are fixedly installed at the bottom of the transverse connecting plate 403, and the top ends of the vertical connecting rods 402 are fixedly connected with the corresponding convex columns 404.
The automatic pipette installing device is characterized in that a first longitudinal screw 2031 is fixedly installed on an output shaft of the first motor 203, a first internal thread sleeve 2032 is sleeved on the first longitudinal screw 2031 in a threaded manner, one side, close to the transverse connecting plate 403, of the first internal thread sleeve 2032 is fixedly connected with the transverse connecting plate 403, a second longitudinal screw 2041 is fixedly installed on an output shaft of the second motor 204, a second internal thread sleeve 2042 is sleeved on an output shaft of the second longitudinal screw 2041 in a threaded manner, and one side, close to the pipette installing unit 4, of the second internal thread sleeve 2042 is fixedly connected with the pipette installing unit 4.
When the pipette head 401 on the pipette installation unit 4 moves up and down as required, the second motor 204 is directly started, the second motor 204 drives the second longitudinal screw 2041 to move, the second longitudinal screw 2041 drives the second internal thread sleeve 2042 to move, and then the pipette head 401 can move and change according to the up and down movement;
y-axis slide rails are fixedly mounted on the inner walls of the two sides of the clip-shaped frame 202, Y-axis slide rails are slidably mounted on the Y-axis slide rails, and the two sides of the pipettor mounting unit 4 are fixedly connected with the two Y-axis slide rails respectively.
If the pipette tip 401 needs to be detached, the first motor 203 is directly started, the first motor 203 drives the first longitudinal screw 2031 to move, the first longitudinal screw 2031 drives the first internal thread sleeve 2032 to move, the first internal thread sleeve 2032 drives the convex column 404 to move, the convex column 404 drives the vertical connecting rod 402 to move downwards, and then the pipette tip 401 can be pushed out to be detached.
Threaded holes are formed in the square frame 202 and are in threaded connection with the transverse screw 301, and four supporting legs are fixedly mounted at the bottom of the console 201.
The protective device is characterized in that a square cabinet door 101 is arranged on the square protective cover 1, the square cabinet door 101 is hinged to the square protective cover 1 through a hinge, a door handle 102 is fixedly mounted on the square cabinet door 101, and a liquid crystal display screen 103 and a switch button 104 are arranged on the square protective cover 1.
It should be noted that the device structure and the accompanying drawings of the present invention mainly describe the principle of the present invention, and in the design principle, the settings of the power mechanism, the power supply system, the control system, etc. of the device are not completely described, and on the premise that the skilled person understands the principle of the present invention, the details of the power mechanism, the power supply system, and the control system can be clearly known, the control mode of the application file is automatically controlled by the controller, and the control circuit of the controller can be realized by simple programming of the skilled person in the art;
the standard parts used in the method can be purchased from the market, and can be customized according to the description of the specification and the accompanying drawings, the specific connection mode of each part adopts conventional means such as mature bolts, rivets, welding and the like in the prior art, the machines, parts and equipment adopt conventional models in the prior art, and the structure and the principle of the parts known by the skilled person can be known by technical manuals or conventional experimental methods.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made herein without departing from the principles and spirit of the invention, and it is intended that in other related fields of technology, the scope of the invention be limited only by the claims and their equivalents, all of which are included within the scope of the present invention as defined in the appended claims.

Claims (5)

1. The full-automatic analysis device for the small enzyme-linked immunosorbent assay is characterized by comprising full-automatic analysis equipment arranged in a square protective cover, wherein an opening is formed in the bottom of the square protective cover, the full-automatic analysis equipment comprises a console, the console is in contact with the square protective cover, a CCD camera is arranged in the square protective cover, a clip-shaped frame is arranged above the console, a first motor and a second motor are arranged on the clip-shaped frame, an Contraband-type placing table is fixedly arranged at the top of the console, a collecting box, two storage boxes, a reaction liquid-transferring unit and an imaging detection unit are connected to the Contraband-type placing table, and a transverse moving mechanism and a longitudinal moving mechanism are arranged on the console;
the transverse moving mechanism comprises a motor III, the motor III is fixedly installed at the top of the console, a transverse screw is fixedly installed on an output shaft of the motor III, two X-axis slide rails are fixedly installed at the top of the console, an X-axis slide rail is installed on the X-axis slide rails in a sliding mode, the top of the X-axis slide rail is fixedly connected with the clip-shaped frame, and one end, far away from the motor III, of the transverse screw is installed on the clip-shaped frame in a threaded mode;
the vertical moving mechanism comprises a pipettor installation unit, the pipettor installation unit is slidably installed on the clip frame, a plurality of pipette heads are arranged on the pipettor installation unit and located below the pipettor installation unit, a plurality of vertical connecting rods are arranged on the pipettor installation unit and adapted to the corresponding pipette heads, a transverse connecting plate is arranged above the pipettor installation unit and slidably installed on the clip frame, a plurality of convex columns are fixedly installed at the bottom of the transverse connecting plate, and the top ends of the vertical connecting rods are fixedly connected with the corresponding convex columns.
2. The full-automatic analysis device for the small enzyme-linked immunosorbent assay according to claim 1, wherein a first longitudinal screw is fixedly mounted on an output shaft of the first motor, a first internal thread sleeve is sleeved on an upper thread of the first longitudinal screw, one side, close to the transverse connecting plate, of the first internal thread sleeve is fixedly connected with the transverse connecting plate, a second longitudinal screw is fixedly mounted on an output shaft of the second motor, a second internal thread sleeve is sleeved on an output shaft of the second longitudinal screw, and one side, close to the pipette mounting unit, of the second internal thread sleeve is fixedly connected with the pipette mounting unit.
3. The full-automatic analysis device for the small enzyme-linked immunosorbent assay according to claim 1, wherein the inner walls of the two sides of the rectangular frame are fixedly provided with Y-axis slide rails, the Y-axis slide rails are slidably provided with Y-axis slide ways, and the two sides of the pipette installation unit are respectively and fixedly connected with the two Y-axis slide ways.
4. The full-automatic analysis device for the small enzyme-linked immunosorbent assay according to claim 1, wherein the clip-shaped frame is provided with a threaded hole, the threaded hole is in threaded connection with the transverse screw, and the bottom of the console is fixedly provided with four support legs.
5. The device according to claim 1, wherein a square door is provided on the square protective cover, the square door is hinged to the square protective cover by a hinge, a door handle is fixedly mounted on the square door, and a liquid crystal display and a switch button are provided on the square protective cover.
CN202220303290.7U 2022-02-15 2022-02-15 Full-automatic analytical equipment is used in small-size ELISA adsorption test Active CN217278397U (en)

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CN202220303290.7U CN217278397U (en) 2022-02-15 2022-02-15 Full-automatic analytical equipment is used in small-size ELISA adsorption test

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Application Number Priority Date Filing Date Title
CN202220303290.7U CN217278397U (en) 2022-02-15 2022-02-15 Full-automatic analytical equipment is used in small-size ELISA adsorption test

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117706087A (en) * 2024-02-01 2024-03-15 山东益生种畜禽股份有限公司 Portable detection device for bursa mycoplasma MS-ONE

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117706087A (en) * 2024-02-01 2024-03-15 山东益生种畜禽股份有限公司 Portable detection device for bursa mycoplasma MS-ONE
CN117706087B (en) * 2024-02-01 2024-04-16 山东益生种畜禽股份有限公司 Portable detection device for bursa mycoplasma MS-ONE

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Effective date of registration: 20230726

Address after: Rooms 1204 and 1205, Building 1, No. 188 Fuchunjiang Road, High tech Zone, Suzhou City, Jiangsu Province, 215000

Patentee after: Jiangsu Xiangzhong Technology Co.,Ltd.

Address before: 210000 floor 6, building 2, Shuanglong Science Park, No. 1, Shuanglong street, Qinhuai District, Nanjing, Jiangsu Province

Patentee before: NANJING XIANGZHONG BIOTECHNOLOGY Co.,Ltd.