CN217249769U - Centrifugal device and liquid-based film-making equipment - Google Patents

Centrifugal device and liquid-based film-making equipment Download PDF

Info

Publication number
CN217249769U
CN217249769U CN202123156666.0U CN202123156666U CN217249769U CN 217249769 U CN217249769 U CN 217249769U CN 202123156666 U CN202123156666 U CN 202123156666U CN 217249769 U CN217249769 U CN 217249769U
Authority
CN
China
Prior art keywords
pipetting
liquid
centrifuge
supernatant
driving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202123156666.0U
Other languages
Chinese (zh)
Inventor
刘剑
林冲
张安
李建洪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Reetoo Biotechnology Co Ltd
Original Assignee
Shenzhen Reetoo Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Reetoo Biotechnology Co Ltd filed Critical Shenzhen Reetoo Biotechnology Co Ltd
Priority to CN202123156666.0U priority Critical patent/CN217249769U/en
Application granted granted Critical
Publication of CN217249769U publication Critical patent/CN217249769U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Centrifugal Separators (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model is suitable for the field, and discloses a centrifugal device and liquid-based film-making equipment, wherein the centrifugal device comprises a centrifugal mechanism, a first liquid-transferring mechanism and a second liquid-transferring mechanism; the centrifugal mechanism is used for carrying out primary centrifugal treatment and secondary centrifugal treatment on the centrifugal tube loaded with the sample; the first liquid transferring mechanism and the second liquid transferring mechanism are arranged independently, the first liquid transferring mechanism is used for sucking the supernatant liquid after the first centrifugal treatment, and the second liquid transferring mechanism is used for sucking the supernatant liquid after the second centrifugal treatment. Through setting up two liquid-transfering mechanism, can be under the circumstances that does not increase the degree of difficulty of control program control, absorb twice through first liquid-transfering mechanism and second liquid-transfering mechanism with different absorption speed and handle the supernatant clean.

Description

Centrifugal device and liquid-based film-making equipment
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a centrifugal device and liquid-based film-making equipment.
Background
The liquid-based cytology examination adopts a liquid-based thin-layer cell detection system to detect cells and carry out cytological classification diagnosis. In-process at liquid-based sample film-making, carry out twice centrifugation usually, the supernatant is once drawn in every centrifugation, all absorb the supernatant with same imbibition mechanism after two centrifugation in the prior art, however, do so has an drawback, because the supernatant is just tentatively drawn in first centrifugation, so can absorb fast when absorbing, but need absorb all supernatants after the centrifugation of second time totally, the process that the supernatant was absorbed to the event second time is slower, consequently if absorb with an imbibition mechanism with same speed, it has the residue to handle the supernatant, if absorb with an imbibition mechanism with different speeds, undoubtedly need to go to realize through the control of procedure, increase program control's degree of difficulty. Therefore, there is a need to design a supernatant processing scheme that can process the supernatant cleanly and does not increase the difficulty of program control.
SUMMERY OF THE UTILITY MODEL
A first object of the present invention is to provide a centrifuge, which aims to solve the technical problems of unclean supernatant treatment and high difficulty of program control.
In order to achieve the above purpose, the utility model provides a scheme is: a centrifuge device comprising:
the centrifugal mechanism is used for carrying out primary centrifugal treatment and secondary centrifugal treatment on the centrifuge tube loaded with the sample;
the first liquid moving mechanism and the second liquid moving mechanism are arranged independently, the first liquid moving mechanism is used for sucking the supernatant after the first centrifugal treatment, and the second liquid moving mechanism is used for sucking the supernatant after the second centrifugal treatment.
Optionally, the centrifuge device further comprises a first effluent collection tank, and the first pipetting mechanism is used for sucking the supernatant and discharging the supernatant into the first effluent collection tank.
Optionally, the first pipetting mechanism comprises a first pipetting piece for pipetting a supernatant and a first driving device for driving the first pipetting piece, the first pipetting piece being a pipetting needle.
Optionally, the first pipetting mechanism comprises a first pipetting piece and a first driving device, the first pipetting piece is a pipetting tip; the first pipetting piece is detachably connected to the first driving device, and the first driving device is used for driving the first pipetting piece to move from the centrifugal mechanism to the first waste liquid recovery tank.
Optionally, the centrifugation apparatus further comprises a first carrier for carrying the first pipetting member and a first recovery assembly for recovering the first pipetting member, and the first driving apparatus is further for driving the first pipetting member to move from the first carrier to the centrifugation mechanism and for driving the first pipetting member to move from the first effluent collection well to the first recovery assembly.
Optionally, the second pipetting mechanism comprises a second pipetting member and a second driving device, the second pipetting member being a pipetting tip; the second pipetting piece is detachably connected to the second driving device, the first recovery assembly is further used for recovering the second pipetting piece, and the second driving device is used for driving the second pipetting piece to move to the first recovery assembly.
Optionally, the second pipetting mechanism is used for sucking the supernatant and discharging the supernatant into the first waste liquid recovery tank.
Optionally, the centrifuge further comprises a second effluent collection tank, and the second pipetting mechanism is used for sucking the supernatant and discharging the supernatant into the second effluent collection tank.
Optionally, the second pipetting mechanism comprises a second pipetting piece for pipetting a supernatant and a second driving device for driving the second pipetting piece, the second pipetting piece being a pipetting needle.
Optionally, the second pipetting mechanism comprises a second pipetting member and a second driving device, the second pipetting member being a pipetting tip; the second driving device is used for driving the second pipetting piece to move.
Optionally, the centrifuge device further comprises a second carrier for carrying the second pipetting member and a second recovery assembly for recovering the second pipetting member.
Optionally, the capacity of the first pipetting mechanism is greater than or equal to the capacity of the second pipetting mechanism.
A second object of the present invention is to provide a liquid-based tablet making apparatus, including the above-mentioned centrifugal device.
Compared with the prior art, the beneficial effects of the utility model reside in that:
the utility model provides a centrifugal device and liquid-based film-making equipment, wherein the centrifugal device comprises a centrifugal mechanism, a first liquid-transferring mechanism and a second liquid-transferring mechanism; the centrifugal mechanism is used for carrying out primary centrifugal treatment and secondary centrifugal treatment on the centrifugal tube loaded with the sample; the first liquid transferring mechanism and the second liquid transferring mechanism are arranged independently, the first liquid transferring mechanism is used for sucking the supernatant liquid after the first centrifugal treatment, and the second liquid transferring mechanism is used for sucking the supernatant liquid after the second centrifugal treatment. Through setting up two liquid moving mechanisms, can be under the condition of the degree of difficulty that does not increase control program control, absorb twice through first liquid moving mechanism and second liquid moving mechanism with different absorption rate and handle the supernatant clean.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
Fig. 1 is a schematic perspective view of a liquid-based film-making apparatus according to an embodiment of the present invention;
fig. 2 is a schematic perspective view of a part of liquid-based film-making equipment according to an embodiment of the present invention;
FIG. 3 is an enlarged schematic view at A in FIG. 2;
fig. 4 is a schematic plan view of a centrifugal apparatus according to an embodiment of the present invention;
fig. 5 is a schematic perspective view of a second recycling assembly according to a first embodiment of the present invention;
fig. 6 is a schematic plan view of a second driving device provided in accordance with a first embodiment of the present invention;
fig. 7 is a perspective view of a second carriage according to a first embodiment of the present invention;
fig. 8 is a schematic perspective view of a second pipetting device provided by an embodiment of the present invention;
fig. 9 is a schematic plan view of a centrifuge according to a fourth embodiment of the present invention;
fig. 10 is a schematic plan view of a liquid-based film-making apparatus provided by a sixth embodiment of the present invention.
The reference numbers illustrate:
100. a centrifugal device; 110. a centrifugal mechanism; 111. a bearing seat; 112. centrifuging the tube; 120. a first pipetting mechanism; 121. a first pipetting member; 122. a first driving device; 130. a second pipetting mechanism; 131. a second pipetting member; 1311. a jack; 132. a second driving device; 1321. a component is inserted and taken; 140. a first effluent recovery tank; 150. a second carrier; 151. a housing hole; 160. a second recovery assembly; 161. a separation frame; 1611. a limiting port; 162. a guide member; 170. a second effluent recovery tank;
200. liquid-based film making equipment; 210. a frame; 220. an elution and uniform mixing device; 230. a sedimentation dyeing device; 240. a soaking treatment device.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without making creative efforts belong to the protection scope of the present invention.
It should be noted that all the directional indicators (such as upper, lower, left, right, front, and rear … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture, if the specific posture is changed, the directional indicator is changed accordingly.
It will also be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or be indirectly connected to the other element through intervening elements.
In addition, the descriptions related to "first", "second", etc. in the present invention are for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicit ly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.
The first embodiment is as follows:
as shown in fig. 1-8, in order to achieve the above object, an embodiment of the present invention provides a solution: a centrifuge apparatus 100 includes a centrifuge mechanism 110, a first pipetting mechanism 120, and a second pipetting mechanism 130. The centrifuge mechanism 110 is used to perform a first centrifugation process and a second centrifugation process on a centrifuge tube 112 loaded with a sample. The first pipetting mechanism 120 and the second pipetting mechanism 130 are provided independently of each other, the first pipetting mechanism 120 is used for sucking the supernatant after the first centrifugation, and the second pipetting mechanism 130 is used for sucking the supernatant after the second centrifugation. Illustratively, the supernatant is a turbid liquid that is located on the upper layer of the cell sample after being centrifuged by the centrifugation mechanism 110. At the sample film-making in-process, only tentatively absorb the supernatant after the centrifugation for the first time, so can absorb fast when absorbing, but need absorb all supernatants totally after the centrifugation for the second time, so the process of absorbing the supernatant for the second time is slower, consequently if absorb with a imbibition mechanism with same speed, it can remain to handle the supernatant, if absorb with a imbibition mechanism with different speeds, undoubtedly need to go to realize through the control of procedure, increases program control's the degree of difficulty. Thus, the present application provides a centrifuge device 100 provided with two pipetting mechanisms for pipetting two supernatants at different rates, respectively. That is, the suction rate of the first pipetting mechanism 120 is faster than the suction rate of the second pipetting mechanism 130. And two liquid-transfering mechanisms are arranged, the start and stop of the two liquid-transfering mechanisms are only required to be controlled, the suction speed can be set in advance, the control is not required, and the control is relatively simple.
As shown in fig. 3 and 4, the centrifuge apparatus 100 further includes a first effluent collecting tank 140, and the first pipetting mechanism 120 is configured to aspirate and discharge the supernatant into the first effluent collecting tank 140. The first effluent collecting tank 140 is connected to a first storage container (not shown in the figure) through a first pipeline assembly (not shown in the figure), the pipeline assembly is further provided with a control valve assembly (not shown in the figure) for controlling the on-off of the pipeline and a first pump body (not shown in the figure) for providing power, and after the first pipetting mechanism 120 discharges the sucked supernatant to the first effluent collecting tank 140, the supernatant is transferred to the first effluent collecting tank 140 through the pipeline assembly.
As shown in fig. 3 and 4, as one embodiment, the first pipetting mechanism 120 includes a first pipetting member 121 for aspirating a supernatant and a first driving device 122 for driving the first pipetting member 121, and the first pipetting member 121 is a pipetting needle. Illustratively, the first pipetting device 121 of the present embodiment is a pipette needle, the pipette needle is mounted on the first driving device 122, the centrifugation mechanism 110 has a carrying seat 111, the carrying seat 111 has four carrying positions (not shown in the figure) for placing the centrifuge tube 112 with the sample, the first driving device 122 drives the first pipetting device 121 to extend into the centrifuge tube 112 to aspirate the supernatant, and drives the first pipetting device 121 to move to the first effluent collecting tank 140 for discharging. In the present embodiment, the first pipetting members 121 are provided in the same number as the carrying bits and in positions distributed corresponding to the carrying bits, that is, the four first pipetting members 121 are provided in the present embodiment, and the first driving device 122 can drive the four first pipetting members 121 to simultaneously aspirate the supernatant, so that the supernatant obtained by the first centrifugation can be processed at one time, thereby improving the work efficiency. Of course, in a specific application, the number of the first pipetting members 121 and the number of the carrying positions may be equal, for example, three carrying positions and three first pipetting members 121 corresponding to the carrying positions are provided, the number of the first pipetting members 121 is not limited in this application, and it is only necessary to ensure that one set of the first pipetting members 121 can aspirate the supernatant in the centrifuge tube 112 on the carrying seat 111 at one time. Of course, the number of the first pipetting members 121 may not be equal to the number of the loading positions, for example, only one first pipetting member 121 is provided, and the loading positions are provided with a plurality of first pipetting needles for pipetting a plurality of times. In addition, in order to avoid cross contamination, the first pipetting member 121 needs to be cleaned after being used once, the first pipetting member 121 is connected with the second storage container through the second pipeline assembly, and the second storage container stores a rinsing liquid, after the supernatant in the first waste liquid recovery tank 140 is transferred into the first storage container, the control valve assembly controls the first pipeline assembly to be disconnected, the rinsing liquid in the second storage container flows through the first pipetting needle through the second pipeline assembly, at this time, the inner wall of the first pipetting needle is cleaned, the rinsing liquid is discharged into the first waste liquid recovery tank 140, the outer wall of the first pipetting needle is cleaned, after the cleaning, the wastewater is discharged into the first storage container, and at this time, one cleaning process is completed.
As shown in fig. 1 and 3, the second pipetting mechanism 130 is used to aspirate and discharge a supernatant liquid into the first effluent collecting tank 140 as one embodiment. Illustratively, the first pipetting mechanism 120 and the second pipetting mechanism 130 share one waste liquid recovery tank, which can save space and is beneficial to realizing the miniaturization of the device.
As shown in fig. 1, 3, and 8, the second pipetting mechanism 130 includes a second pipetting member 131 and a second driving device 132, and the second pipetting member 131 is a pipetting tip; the second driving device 132 is used for driving the second pipetting member 131 to move. The second driving device 132 illustratively has an insertion component 1321 for inserting the pipetting tip, and the insertion component 1321 is inserted into the pipetting tip and drives the pipetting tip to move. The liquid transfer suction head is also called tip head, and the liquid transfer suction head is a disposable article and is recovered after being used. The top of the pipette tip is provided with a receptacle 1311 fitted with an insertion part 1321, and the insertion part 1321 is fitted with the receptacle 1311 to pick up the pipette tip. The liquid-transfering suction head is made of plastic material and has certain elasticity. The insertion part 1321 is tapered at its end and the insertion part 1321 has an outer diameter slightly larger than the diameter of the insertion hole 1311, so that the insertion part 1321 can be inserted into the insertion hole 1311 having a smaller diameter than the outer diameter of the insertion part 1321 by elasticity, and the insertion part 1321 can be detachably connected to the insertion hole 1311 of the pipette tip to enable the pipette tip to be inserted and detached.
As shown in fig. 3, 5 and 7, the centrifugation apparatus 100 further includes a second carriage 150 and a second recovery assembly 160, wherein the second carriage 150 is used for carrying the second pipetting member 131, and the second recovery assembly 160 is used for recovering the second pipetting member 131. The second recovery assembly 160 comprises a separating rack 161, a recovery box (not shown in the figure) and a guiding member 162, wherein the separating rack 161 is provided with a limiting opening 1611, and the limiting opening 1611 is used for limiting the pipette tips on the inserting component 1321 so as to separate the pipette tips from the inserting component 1321. The spacing port 1611 penetrates through the separation frame 161, the spacing port 1611 comprises a side opening and a spacing hole, the side opening is communicated with the spacing hole, the outer diameter of the inserting and taking component 1321 is smaller than the width of the side opening and smaller than the aperture of the spacing hole, so that the inserting and taking component 1321 can pass through the spacing port 1611, and the pipetting tip cannot pass through the spacing port 1611. Thereby separating the pipette tip from the insertion part 1321 and thus achieving the recovery of the pipette tip. This embodiment is equipped with two spacing mouths 1611, and has certain interval between two spacing mouths 1611, can dismantle the recovery to two liquid-transfering suction heads simultaneously, improve equipment's work efficiency. Of course, the number of spacing ports 1611 is not limited to two in a particular application, and may be three, or four, for example, as an alternative. The collection box is used to collect the second pipetting member 131 that has fallen, and the guide 162 guides the second pipetting member 131 separated from the inserting part 1321 to fall into the collection box. The second carrier 150 is provided with a plurality of accommodating holes 151 for accommodating pipettes, and the plurality of accommodating holes 151 are distributed in multiple rows and multiple columns.
As shown in fig. 1 and 3, the capacity of the first pipetting mechanism 120 is equal to or larger than the capacity of the second pipetting mechanism 130. The first pipetting means 120 pipettes the supernatant after the first centrifugation, and the second pipetting means 130 pipettes the supernatant after the second centrifugation for the preliminary pipetting, and for the further pipetting, so that the amount of the supernatant pipetted for the first time is theoretically more than or equal to the amount of the supernatant pipetted for the second time.
Example two:
the present embodiment differs from the first embodiment mainly in the structure of the first pipetting mechanism 120. The concrete body is as follows: in the first embodiment, the first pipetting member 121 is a pipette needle, and in the present embodiment, the first pipetting member 121 is a pipette tip.
As an embodiment, the first pipetting mechanism 120 includes a first pipetting member 121 and a first driving device 122, the first pipetting member 121 is a pipetting tip; the first pipetting member 121 is detachably connected to a first driving device 122, and the first driving device 122 is used for driving the first pipetting member 121 to move from the centrifugal mechanism 110 to the first effluent collecting tank 140. The first pipetting member 121 of this embodiment is a pipetting tip. The first transfer element 121 of the present embodiment is a disposable article similar in structure and shape to the second transfer element 131 of the first embodiment, and is collected after use. However, the first and second transfer elements 121, 131 may be of different sizes, i.e., the pipetting volume of the first transfer element 121 is greater than that of the second transfer element 131, and the pipette tip used for the first transfer element 121 may need to be placed in another holder.
In one embodiment, the centrifuge apparatus 100 further comprises a first carrier for carrying the first pipetting device 121 and a first recovery assembly for recovering the first pipetting device 121, and the first driving device 122 is further configured to drive the first pipetting device 121 to move from the first carrier to the centrifuge mechanism 110 and to drive the first pipetting device 121 to move from the first effluent collection well 140 to the first recovery assembly. In this embodiment, on the basis of the first embodiment, a first loading frame and a first recovery assembly are further disposed for placing and recovering the first pipetting device 121, and the specific structures of the first loading frame and the first recovery assembly are similar to the structures of the second loading frame 150 and the second recovery assembly 160 provided in the first embodiment, and only the structural design of the second loading frame 150 and the second recovery assembly 160 provided in the first embodiment needs to be performed, which is not described herein again.
In addition to the above differences, the centrifugal device 100 and the structure of the components thereof provided in the present embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.
Example three:
the difference between this embodiment and the second embodiment is mainly that the first pipetting member 121 and the second pipetting member 131 are both retrieved by the same retrieval assembly. The concrete expression is as follows:
as an embodiment, the second pipetting mechanism 130 comprises a second pipetting member 131 and a second driving device 132, the second pipetting member 131 being a pipetting tip; the second pipetting member 131 is detachably connected to a second driving device 132, the first recovery assembly is further used for recovering the second pipetting member 131, and the second driving device 132 is used for driving the second pipetting member 131 to move to the first recovery assembly. In this embodiment, the first transfer element 121 is a pipette tip and the second transfer element 131 is a pipette tip, and it should be noted that the first transfer element 121 and the second transfer element 131 in this embodiment have the same structure and shape, are disposable articles, and are collected after use. That is, it is equivalent to the first pipetting member 121 and the second pipetting member 131 being placed in the first carrier frame in the second embodiment without placing the second pipetting member 131 in a separate carrier frame. And the pipetting tips employed by the first pipetting member 121 and the second pipetting member 131 can be recovered using the first recovery assembly.
In addition to the above differences, the centrifugal device 100 and the structure of the components thereof provided in the present embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.
Example four:
as shown in fig. 9, the present embodiment is different from the first to third embodiments mainly in that the first pipetting mechanism 120 and the second pipetting mechanism 130 do not share one effluent collecting tank. The concrete expression is as follows:
in one embodiment, the centrifuge 100 further comprises a second effluent collecting tank 170, and the second pipetting mechanism 130 is used for pipetting and discharging the supernatant into the second effluent collecting tank 170. In the first to third embodiments, the first effluent collecting tank 140 is provided, that is, the first pipetting mechanism 120 and the second pipetting mechanism 130 share one effluent collecting tank, and the second effluent collecting tank 170 is added in the present embodiment, that is, the first pipetting mechanism 120 discharges the supernatant into the first effluent collecting tank 140, that is, the second pipetting mechanism 130 discharges the supernatant into the second effluent collecting tank 170. In the present embodiment, two effluent collecting baths are provided to avoid such a problem, considering that the interference between the first pipetting mechanism 120 and the second pipetting mechanism 130 may occur by sharing one effluent collecting bath.
In addition to the above differences, the centrifugal device 100 and the structure of the components thereof provided in the present embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.
Example five:
the difference between this embodiment and the first embodiment is mainly the structure of the second pipetting member 131. The concrete expression is as follows: in the first embodiment, the second pipetting member 131 is a pipetting tip, and in the present embodiment, the second pipetting member 131 is a pipetting needle.
As an embodiment, the second pipetting mechanism 130 includes a second pipetting member 131 for pipetting the supernatant and a second driving device 132 for driving the second pipetting member 131, and the second pipetting member 131 is a pipetting needle. For example, the second pipetting member 131 in the first to third embodiments uses a pipetting tip, in this embodiment, the second pipetting member 131 uses a pipetting needle, the specific structure of which is the same as that of the first pipetting member 121 in the first embodiment, and only the structural design of the first pipetting member 121 in the first embodiment needs to be performed, which is not described herein again.
In addition to the above differences, the centrifugal device 100 and the structure of the components thereof provided in the present embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.
Example six:
as shown in fig. 10, the present embodiment is different from the first to sixth embodiments mainly in the main body of protection. The concrete expression is as follows:
a second object of the present invention is to provide a liquid-based sheet manufacturing apparatus 200, including the above-mentioned centrifugal device 100. The liquid-based tableting equipment 200 includes an elution blending device 220, the above-mentioned centrifugal device 100, a sedimentation dyeing device 230, and a soaking treatment device. The elution and blending device 220 is used for eluting and blending the samples in the sample container; the centrifugal device 100 is used for centrifuging the sample after elution and mixing; the sedimentation dyeing device 230 is used for carrying out sedimentation and dyeing treatment on the centrifuged sample; the soaking device is used for soaking the dyed sample. The liquid-based sheet-making apparatus 200 further includes a frame 210, and the eluting and mixing device 220, the centrifuging device 100, the sedimentation dyeing device 230, and the soaking device are all disposed on the frame 210. The liquid-based slide making equipment 200 provided by the application can automatically realize the whole process of slide making, and comprises but is not limited to the steps of sample feeding, sample elution and uniform mixing, reagent adding, centrifugal treatment, sedimentation dyeing, soaking treatment, slide output and the like.
The application provides a liquid-based wafer manufacturing apparatus comprising the centrifugation device of the first to fifth embodiments, wherein the centrifugation device comprises a centrifugation mechanism, a first liquid-transferring mechanism and a second liquid-transferring mechanism; the centrifugal mechanism is used for carrying out primary centrifugal treatment and secondary centrifugal treatment on the centrifugal tube loaded with the sample; the first liquid transferring mechanism and the second liquid transferring mechanism are arranged independently, the first liquid transferring mechanism is used for sucking the supernatant liquid after the first centrifugal treatment, and the second liquid transferring mechanism is used for sucking the supernatant liquid after the second centrifugal treatment. By arranging the two pipetting mechanisms, the device can completely treat the supernatant by two times of suction by the first pipetting mechanism and the second pipetting mechanism at different suction rates without increasing the difficulty of control program control.
In addition to the above differences, the centrifugal device 100 and the structure of the components thereof provided in the present embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.
The above only be the preferred embodiment of the utility model discloses a not consequently restriction the utility model discloses a patent range, all are in the utility model discloses a conceive, utilize the equivalent structure transform of what the content was done in the description and the attached drawing, or direct/indirect application all is included in other relevant technical field the utility model discloses a patent protection within range.

Claims (13)

1. A centrifuge device, comprising:
the centrifugal mechanism is used for carrying out primary centrifugal treatment and secondary centrifugal treatment on the centrifuge tube loaded with the sample;
the first liquid moving mechanism and the second liquid moving mechanism are arranged independently, the first liquid moving mechanism is used for sucking the supernatant after the first centrifugal treatment, and the second liquid moving mechanism is used for sucking the supernatant after the second centrifugal treatment.
2. The centrifuge of claim 1, further comprising a first effluent collection basin, said first pipetting mechanism to aspirate and discharge supernatant into said first effluent collection basin.
3. The centrifuge of claim 2, wherein said first pipetting mechanism comprises a first pipetting member for aspirating supernatant and a first driving means for driving said first pipetting member, said first pipetting member being a pipetting needle.
4. The centrifuge of claim 2, wherein said first pipetting mechanism comprises a first pipetting member and a first drive means, said first pipetting member being a pipetting tip; the first pipetting piece is detachably connected to the first driving device, and the first driving device is used for driving the first pipetting piece to move from the centrifugal mechanism to the first waste liquid recovery tank.
5. The centrifuge of claim 4, further comprising a first carrier for carrying said first pipetting member and a first recovery assembly for recovering said first pipetting member, said first drive means further for driving said first pipetting member from said first carrier to said centrifuge mechanism and for driving said first pipetting member from said first effluent collection well to said first recovery assembly.
6. The centrifuge of claim 5, wherein said second pipetting mechanism comprises a second pipetting member and a second drive means, said second pipetting member being a pipetting tip; the second pipetting piece is detachably connected to the second driving device, the first recovery assembly is further used for recovering the second pipetting piece, and the second driving device is used for driving the second pipetting piece to move to the first recovery assembly.
7. The centrifuge of claim 2, wherein said second pipetting mechanism is configured to aspirate supernatant and discharge it into said first effluent collection well.
8. The centrifuge of claim 1, further comprising a second effluent collection tank, said second pipetting mechanism for aspirating supernatant and discharging into said second effluent collection tank.
9. A centrifugation device according to claim 7 or 8, characterized in that the second pipetting means comprise a second pipetting member for pipetting a supernatant and second driving means for driving the second pipetting member, the second pipetting member being a pipetting needle.
10. The centrifuge device of claim 7 or 8, wherein said second pipetting mechanism comprises a second pipetting member and a second drive means, the second pipetting member being a pipetting tip; the second driving device is used for driving the second pipetting piece to move.
11. The centrifuge of claim 10, further comprising a second carrier for carrying the second pipettes and a second recovery assembly for recovering the second pipettes.
12. The centrifuge of any of claims 1-8, wherein the capacity of said first pipetting mechanism is greater than or equal to the capacity of said second pipetting mechanism.
13. A liquid-based sheet making apparatus comprising a centrifuge device according to any of claims 1 to 12.
CN202123156666.0U 2021-12-15 2021-12-15 Centrifugal device and liquid-based film-making equipment Active CN217249769U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202123156666.0U CN217249769U (en) 2021-12-15 2021-12-15 Centrifugal device and liquid-based film-making equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202123156666.0U CN217249769U (en) 2021-12-15 2021-12-15 Centrifugal device and liquid-based film-making equipment

Publications (1)

Publication Number Publication Date
CN217249769U true CN217249769U (en) 2022-08-23

Family

ID=82888382

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202123156666.0U Active CN217249769U (en) 2021-12-15 2021-12-15 Centrifugal device and liquid-based film-making equipment

Country Status (1)

Country Link
CN (1) CN217249769U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023109914A1 (en) * 2021-12-15 2023-06-22 深圳市瑞图生物技术有限公司 Liquid-based slide preparation device and slide preparation method of sample

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023109914A1 (en) * 2021-12-15 2023-06-22 深圳市瑞图生物技术有限公司 Liquid-based slide preparation device and slide preparation method of sample

Similar Documents

Publication Publication Date Title
DE202018106740U1 (en) ChemiLuminescent
KR101201005B1 (en) Separation container, attachment and separation method
CN217249769U (en) Centrifugal device and liquid-based film-making equipment
CN115754323A (en) Automated diagnostic analyzer and method for operation of an automated diagnostic analyzer
EP2025418A1 (en) Automatic analyzer with pipette cleaning
CN102472695A (en) Nucleic acid extraction kit, nucleic acid extraction method, and nucleic acid extraction apparatus
CN203908840U (en) Microcomputer-controlled liquid-based cell sheet preparation dyeing system
CN211402409U (en) Full-automatic chemiluminescence immunoassay analyzer
CN115493900A (en) Liquid-based slide production apparatus and method for producing specimen
CN112920948A (en) Nucleic acid detection pretreatment instrument
CN108535068A (en) A kind of cytology DNA detections Sample preservation liquid pretreatment unit
KR101587975B1 (en) System and Controlling Method Forautomatic Cell Smear
CN217359218U (en) Liquid-based film-making equipment
US20090171246A1 (en) Method and Implement for Opening Hole in Soft Material
CN216025026U (en) Test tube separation output device
CN217385510U (en) Biochemical analyzer
CN212483096U (en) Liquid-based cell film-making dyeing all-in-one
CN113267396B (en) Cell film-making dyeing machine
CN114895047A (en) Sample analyzer
CN115468820A (en) Liquid-based sample treatment equipment
CN210613766U (en) Translation device of micro-fluidic sample processing equipment
CN113295856A (en) High-throughput virus detection device and application thereof in detection of new coronavirus
CN217359925U (en) Liquid-transfering suction head bears recovery unit and elution mixing device of dish
CN112961769A (en) Single-channel single-cell nucleic acid processing instrument
CN114414749B (en) Method for detecting bacterial count in liquid food and extraction equipment thereof

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant