CN216513833U - Virus detection pretreatment system - Google Patents
Virus detection pretreatment system Download PDFInfo
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- CN216513833U CN216513833U CN202122583587.1U CN202122583587U CN216513833U CN 216513833 U CN216513833 U CN 216513833U CN 202122583587 U CN202122583587 U CN 202122583587U CN 216513833 U CN216513833 U CN 216513833U
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- centrifuge tube
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- tube
- pretreatment system
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Abstract
The utility model relates to the technical field of automatic equipment, and discloses a virus detection pretreatment system which comprises a centrifuge tube array unit, a centrifuge tube cover opening and closing unit, a liquid transfer unit and a pore plate output unit, wherein the centrifuge tube array unit, the centrifuge tube cover opening and closing unit, the liquid transfer unit and the pore plate output unit are arranged on a rack, the centrifuge tube array unit comprises a disk rack and a centrifuge tube array arranged on the disk rack, a centrifuge tube clamping device is arranged on the rack above the centrifuge tube array unit, the centrifuge tube cover opening and closing unit comprises a centrifuge tube fixing device and a centrifuge tube cover opening and closing device, the liquid transfer unit comprises a gun head box and a liquid transfer device, the gun head box is internally provided with the gun head array, the pore plate output unit comprises a pore plate seat and a pore plate arranged on the pore plate seat, and the pore plate seat is arranged on a rotating shaft. According to the utility model, through reasonable layout, operations such as sampling and liquid injection are automatically completed, the working efficiency is improved, and the data accuracy is ensured.
Description
Technical Field
The utility model relates to the technical field of automation equipment, in particular to a virus detection pretreatment system.
Background
The virus nucleic acid detection process has very high danger and needs to be carried out in a high-grade biosafety cabinet. The operation process is from the input of reagent centrifuging tube, uncapping and get liquid, annotate liquid to orifice plate etc. and all need artifical repeated work, and not only work load is big, produces the cross contamination of sample and the confusion of data moreover easily, brings uncertain result for the testing process.
With the development of automation technology, the manual labor can be completely completed through automatic mechanical operation.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the problems and provides a virus detection pretreatment system which can automatically complete operations such as sampling, liquid injection and the like through reasonable layout, improve the working efficiency and ensure the data accuracy.
The technical scheme adopted by the utility model is as follows:
a virus detection pretreatment system is characterized by comprising a centrifuge tube array unit, a centrifuge tube cover opening and closing unit, a liquid transfer unit and an orifice plate output unit which are arranged on a rack, wherein the centrifuge tube array unit comprises a disk rack and a centrifuge tube array arranged on the disk rack, a centrifuge tube clamping device is arranged on the rack above the centrifuge tube array unit, the centrifuge tube cover opening and closing unit comprises a centrifuge tube fixing device and a centrifuge tube cover opening and closing device, the liquid transfer unit comprises a gun head box and a liquid transfer device, the gun head array is arranged in the gun head box, the orifice plate output unit comprises an orifice plate seat and an orifice plate arranged on the orifice plate seat, the orifice plate seat is arranged on a rotating shaft, the centrifuge tube array unit is clamped by the centrifuge tube clamping device and then sent to the centrifuge tube cover opening and closing unit, and the centrifuge tube cover opening and closing unit fixes a centrifuge tube through the centrifuge tube fixing device, the centrifuge tube is opened by the centrifuge tube cover opening and closing device, the pipetting unit takes out quantitative reagents from the centrifuge tube after matching with the gun head in the gun head box and then sends the quantitative reagents into the pore plate of the pore plate output unit, the centrifuge tube cover opening and closing unit closes the centrifuge tube, and the pore plate seat of the pore plate output unit rotates and then outputs the pore plate.
Further, the frame rear sets up the X axle slide rail, the device is got to the centrifuging tube clamp and all sets up on the X axle slide rail through Y axle slide rail and Z axle lift rail with liquid-moving device.
Further, centrifuging tube array unit includes a plurality of plate rail that set up side by side, sets up the centrifuging tube array on every plate rail, centrifuging tube presss from both sides to get the device and presss from both sides the back to remove to the centrifuging tube cover unit that opens and shuts to predetermined centrifuging tube.
Further, centrifuging tube fixing device sets up on horizontal track, centrifuging tube is opened and is closed the lid device and set up in horizontal track top, centrifuging tube fixing device, horizontal track and centrifuging tube are opened and are closed the lid device and be two, set up a centrifuging tube fixing device on every horizontal track, and two centrifuging tube are opened and are closed the lid device and set up between two horizontal tracks.
Further, set up the scanning head in the centrifuging tube fixing device, centrifuging tube is opened and is closed the lid device and when uncapping the centrifuging tube, scans with the rotatory a week of centrifuging tube.
Furthermore, the pipette tip boxes of the pipetting unit are multiple, a pipette tip array is arranged in each pipette tip box, and the number of the pipette tips in the pipette tip boxes is not less than the total number of the centrifuge tubes in the centrifuge tube array unit.
Further, one side of the gun head box is provided with a gun head discarding box.
Further, the orifice plate output unit comprises two orifice plate boxes arranged on the orifice plate seat and hole positions of the two orifice plate boxes, and the rotating shaft of the orifice plate seat drives the orifice plate seat to rotate outwards to the outside of the rack.
Further, the number of centrifuge tubes of the centrifuge tube array unit is 2 × 96, and the number of well plate holes of the well plate output unit is 2 × 96.
Further, the virus detection pretreatment system is installed in a biological safety cabinet.
The utility model has the beneficial effects that:
(1) high-efficiency pretreatment is realized, and 192 samples can be processed at one time;
(2) the potential safety hazard is reduced, and the working environment of the operators is improved.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention;
FIG. 2 is a partially enlarged schematic view of a centrifuge tube array unit;
FIG. 3 is a partially enlarged schematic view of the centrifuge tube cover opening and closing unit;
FIG. 4 is an enlarged partial schematic view of the pipetting unit;
FIG. 5 is an enlarged partial schematic view of an orifice plate output unit;
FIG. 6 is a schematic diagram of the construction of the biological safety cabinet.
Detailed Description
The following describes in detail a specific embodiment of the virus pretreatment system of the present invention with reference to the drawings.
Referring to fig. 1, the virus detection pretreatment system is arranged on a rack 1, and the height of the rack 1 is suitable for a worker to operate. Arrange in proper order from right side to left on frame 1 and set up centrifuging tube array unit 2, centrifuging tube open and shut and cover unit 3, move liquid unit 4 and orifice plate output unit 5.
Referring to fig. 2, the tube array unit 2 includes a tray 6 and an array of tubes 7 disposed on the tray 6, and a tube gripper 8 disposed on the rack 1 above the tube array unit 2. Centrifuge tube array unit 2 includes a plurality of plate rail 6 that set up side by side, sets up centrifuge tube array 7 on every plate rail 6, and centrifuge tube presss from both sides and gets device 8 and move to centrifuge tube opening and shutting cover unit 3 after pressing from both sides predetermined centrifuge tube. Only one tray 6 is shown in the figure, with a space on the left for placing another tray 6. The number of tubes in each tray 6 is 96, and the two trays 6 in the figure have 2 × 96 tubes.
The rear of the rack 1 is provided with an X-axis slide rail 9, and the centrifugal tube clamping device 8 is arranged on the X-axis slide rail 9 through a Y-axis slide rail 10 and a Z-axis lifting rail 11. The clamping jaws arranged on the Z-axis lifting rail 11 are used for clamping centrifugal tubes in the centrifugal tube array 7 and realizing displacement through the movement in the X-axis direction and the Y-axis direction.
Referring to fig. 3, centrifuge tube open/close cover unit 3 includes centrifuge tube fixing device 12 and centrifuge tube open/close cover device 13, and centrifuge tube fixing device 12 sets up on horizontal track 14, and centrifuge tube open/close cover device 13 sets up in horizontal track 14 top, and centrifuge tube fixing device 12, horizontal track 14 and centrifuge tube open/close cover device 13 are two, set up a centrifuge tube fixing device 12 on every horizontal track 14, and two centrifuge tube open/close cover devices 13 set up between two horizontal tracks 14.
In addition, set up scanning head 15 in centrifuging tube fixing device 12, centrifuging tube opening and shutting lid device 13 is when uncapping the centrifuging tube, scans the rotatory a week of centrifuging tube, and the data after the scanning is preserved through control platform, carries out data matching to the sample of every centrifuging tube.
The tube holder 12 is displaced on the horizontal rail 14 and receives the tube gripper 8 to feed the tube to the right. When moving to the intermediate position, scan and open and close the lid, when moving to the left position, make things convenient for the imbibition of liquid moving unit 4.
Referring to fig. 4, the pipetting unit 4 includes a plurality of gun head boxes 16 and a plurality of pipetting devices 17, an array of gun heads is arranged in the gun head box 16, the array of gun heads is arranged in each gun head box 16, and the number of gun heads in the gun head box 16 is not less than the total number of centrifuge tubes in the centrifuge tube array unit 2. I.e. the number of tips is not less than 2 x 96. The liquid transfer device 17 is arranged on an X-axis slide rail 9 behind the frame 1 through a Y-axis slide rail 10 and a Z-axis lifting rail 11, as with the centrifugal tube clamping device 8. The pipetting device 17 moves in the X-axis and Y-axis directions to displace and aspirate and transfer a sample.
In addition, a tip discard box (not shown) is provided on one side of the tip box 16 for collection of waste tips when replacing tips.
Referring to fig. 5, the orifice plate output unit 5 includes an orifice plate seat 18 and an orifice plate 19 disposed on the orifice plate seat 18, the orifice plate seat 18 is disposed on a rotating shaft 20, the orifice plate output unit 5 includes two orifice plate 19 boxes disposed on the orifice plate seat 18, the two orifice plate 19 boxes are located in the hole sites, and the rotating shaft 20 of the orifice plate seat 18 drives the orifice plate seat 18 to rotate outwards to the outside of the rack 1. The number of holes in the orifice plate 19 of the orifice plate output unit 5 is 2 × 96 in the figure.
Referring to fig. 6, the pretreatment system is in accordance with the standard and should operate in the biosafety cabinet 21, and the protection level of the biosafety cabinet 21 should be higher than the P2 level. When the orifice plate 19 is output by the orifice plate seat 18, the orifice plate 19 is extended from the front of the biological safety cabinet 21 and is moved out of the biological safety cabinet 21 to the next station.
The working process of the utility model is that the collected sample is arranged on a tray frame 6 of a centrifuge tube array 7, a centrifuge tube array unit 2 clamps the centrifuge tube by a centrifuge tube clamping device 8 and then sends the centrifuge tube to a centrifuge tube open-close cover unit 3, and the clamping sequence is appointed according to the program. Centrifugal tube open and close lid unit 3 passes through centrifugal tube fixing device 12 and fixes the back with the centrifugal tube, uncaps the centrifugal tube by centrifugal tube open and close lid device 13, waits to move the liquid. After the cover is opened, the bottle cap of the centrifugal tube is clamped by the rotary claw, and the cover is closed after liquid transfer is waited. After the pipette head is matched with the pipette head in the pipette head box 16, the pipetting unit 4 takes out quantitative reagent from the centrifuge tube and then sends the quantitative reagent to the orifice plate 19 of the orifice plate output unit 5, and meanwhile, the centrifuge tube cover closing unit 3 closes the centrifuge tube and sends the centrifuge tube back to the original position of the centrifuge tube array 7 after closing the centrifuge tube cover. After the orifice plate 19 is closed and sealed, the orifice plate 19 is output after being rotated by the orifice plate holder 18 of the orifice plate output unit 5.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. A virus detection pretreatment system is characterized in that: comprises a centrifuge tube array unit, a centrifuge tube cover opening and closing unit, a liquid transfer unit and an orifice plate output unit which are arranged on a rack, wherein the centrifuge tube array unit comprises a disk rack and a centrifuge tube array arranged on the disk rack, a centrifuge tube clamping device is arranged on the rack above the centrifuge tube array unit, the centrifuge tube cover opening and closing unit comprises a centrifuge tube fixing device and a centrifuge tube cover opening and closing device, the liquid transfer unit comprises a gun head box and a liquid transfer device, the gun head array is arranged in the gun head box, the orifice plate output unit comprises an orifice plate seat and an orifice plate arranged on the orifice plate seat, the orifice plate seat is arranged on a rotating shaft, the centrifuge tube array unit clamps the centrifuge tube by the centrifuge tube clamping device and then sends the centrifuge tube to the centrifuge tube cover opening and closing unit, the centrifuge tube cover opening and closing unit opens the centrifuge tube by the centrifuge tube cover opening and closing device after fixing the centrifuge tube by the centrifuge tube fixing device, after the pipette head is matched with the pipette head in the pipette head box, the pipette unit takes out quantitative reagent from the centrifuge tube and sends the quantitative reagent into the pore plate of the pore plate output unit, the centrifuge tube is covered by the centrifuge tube opening and closing unit, and the pore plate seat of the pore plate output unit rotates to output the pore plate.
2. The virus detection pretreatment system according to claim 1, wherein: the frame rear sets up the X axle slide rail, the centrifuging tube clamp is got the device and is all set up on the X axle slide rail through Y axle slide rail and Z axle lift rail with liquid-moving device.
3. The virus detection pretreatment system according to claim 2, wherein: the centrifuge tube array unit comprises a plurality of plate racks arranged side by side, centrifuge tube arrays are arranged on each plate rack, and the centrifuge tube clamping device clamps predetermined centrifuge tubes and then moves to the centrifuge tube cover opening and closing unit.
4. The virus detection pretreatment system according to claim 2, wherein: centrifuging tube fixing device sets up on horizontal track, centrifuging tube is opened and is closed the lid device and set up in horizontal track top, centrifuging tube fixing device, horizontal track and centrifuging tube are opened and are closed the lid device and be two, set up a centrifuging tube fixing device on every horizontal track, and two centrifuging tube are opened and are closed the lid device and set up between two horizontal tracks.
5. The virus detection pretreatment system according to claim 4, wherein: set up the scanning head in the centrifuging tube fixing device, centrifuging tube opening and shutting cover device is when uncapping the centrifuging tube, scans with the rotatory a week of centrifuging tube.
6. The virus detection pretreatment system according to claim 2, wherein: the pipette tip box of the pipetting unit is multiple, a pipette tip array is arranged in each pipette tip box, and the number of the pipette tips in the pipette tip boxes is not less than the total number of the centrifuge tubes in the centrifuge tube array unit.
7. The virus detection pretreatment system according to claim 6, wherein: and a gun head discarding box is arranged on one side of the gun head box.
8. The virus detection pretreatment system according to claim 2, wherein: the pore plate output unit comprises two pore plate boxes arranged on a pore plate seat and pore positions of the two pore plate boxes, and the rotating shaft of the pore plate seat drives the pore plate seat to rotate outwards to the outside of the rack.
9. The virus detection pretreatment system according to any one of claims 1 to 8, wherein: the number of centrifuge tubes of the centrifuge tube array unit is 2 × 96, and the number of the orifice plate holes of the orifice plate output unit is 2 × 96.
10. The virus detection pretreatment system according to any one of claims 1 to 8, wherein: the virus detection pretreatment system is arranged in the biological safety cabinet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122583587.1U CN216513833U (en) | 2021-10-26 | 2021-10-26 | Virus detection pretreatment system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122583587.1U CN216513833U (en) | 2021-10-26 | 2021-10-26 | Virus detection pretreatment system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216513833U true CN216513833U (en) | 2022-05-13 |
Family
ID=81524602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122583587.1U Active CN216513833U (en) | 2021-10-26 | 2021-10-26 | Virus detection pretreatment system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216513833U (en) |
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2021
- 2021-10-26 CN CN202122583587.1U patent/CN216513833U/en active Active
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