CN216208534U - Optical laser chemiluminescence detection system - Google Patents
Optical laser chemiluminescence detection system Download PDFInfo
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- CN216208534U CN216208534U CN202122490172.XU CN202122490172U CN216208534U CN 216208534 U CN216208534 U CN 216208534U CN 202122490172 U CN202122490172 U CN 202122490172U CN 216208534 U CN216208534 U CN 216208534U
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- 238000002038 chemiluminescence detection Methods 0.000 title claims abstract description 15
- 230000003287 optical effect Effects 0.000 title claims description 12
- 238000001514 detection method Methods 0.000 claims abstract description 34
- 230000033001 locomotion Effects 0.000 claims abstract description 19
- 230000001360 synchronised effect Effects 0.000 claims abstract description 17
- 238000000504 luminescence detection Methods 0.000 claims abstract description 13
- 239000011148 porous material Substances 0.000 claims abstract description 12
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 6
- 229910052710 silicon Inorganic materials 0.000 claims description 6
- 239000010703 silicon Substances 0.000 claims description 6
- 230000005284 excitation Effects 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model discloses a light laser chemiluminescence detection system.A warm bath unit is arranged at the upper part of a support mechanism, and the entrance and exit of the warm bath unit are realized through a front-back movement mechanism; the pore plate is arranged in the warm bath unit; the light-emitting detection moving unit is provided with two vertical supporting frames which are arranged at two sides of the warm bath unit, a horizontal unit moving plate is arranged between the vertical supporting frames, two ends of the horizontal unit moving plate are respectively provided with a rotating shaft, a synchronous belt is arranged on the rotating shafts, and the lower part of the horizontal unit moving plate is provided with a horizontal sliding rail; the luminescence detection unit drives the luminescence detection unit to horizontally move left and right through a synchronous belt and a horizontal sliding rail of the luminescence detection moving unit, and the luminescence detection unit is provided with an exciter and a detector. The utility model aims to realize flexible movement and positioning of a sample on the premise of realizing constant temperature control for reducing the pollution of the sample to be detected, so that the sample introduction and detection are smoother and more compact, the automation degree of a detection module is improved, and the detection period is shortened.
Description
Technical Field
The utility model relates to the technical field of immunodiagnosis detection systems, in particular to a light-activated chemiluminescence detection system.
Background
At present, immunoassay is an important means of clinical diagnosis, and the mainstream immunoassay method is a chemiluminescence method, has the characteristics of sensitivity, stability and the like, and is widely applied to clinical detection. The chemiluminescence detection means has obvious advantages compared with immunoassay, but the existing light-activated chemiluminescence detection still has a lot of problems, such as unreasonable temperature control of a detection sample, influence on detection precision, incapability of realizing rapid and flexible movement of the sample and long waiting time of laser detection.
SUMMERY OF THE UTILITY MODEL
The utility model aims to realize flexible movement and positioning of a sample on the premise of realizing constant temperature control for reducing the pollution of the sample to be detected, so that the sample introduction and detection are smoother and more compact, the automation degree of a detection module is improved, and the detection period is shortened.
In order to achieve the purpose, the utility model is realized by the following technical scheme:
an optical laser chemiluminescence detection system, comprising:
the supporting mechanism is arranged at the bottom of the detection system;
the temperature bath unit is arranged at the upper part of the supporting mechanism and realizes the warehousing and the delivery of the temperature bath unit through a front-back movement mechanism;
the pore plate is arranged in the warm bath unit and comprises a plurality of transverse and longitudinal pores;
the light-emitting detection moving unit is provided with two vertical supporting frames which are arranged at two sides of the warm bath unit, a horizontal unit moving plate is arranged between the vertical supporting frames, two ends of the horizontal unit moving plate are respectively provided with a rotating shaft, a synchronous belt is arranged on the rotating shafts, and the lower part of the horizontal unit moving plate is provided with a horizontal sliding rail;
the light-emitting detection unit is driven by a synchronous belt and a horizontal sliding rail of the light-emitting detection moving unit to horizontally move left and right, the light-emitting detection unit is provided with an exciter and a detector, and laser emitted by the exciter can be emitted into a corresponding hole of the pore plate through the movement of the light-emitting detection moving unit. The detector receives the optical signal generated after the sample to be detected is excited, and collects the received optical signal.
Optionally, the front-back movement mechanism comprises a rotating shaft fixedly arranged on the supporting mechanism, and a synchronous belt fixedly connected to the bottom of the temperature bath unit, and the synchronous belt drives the temperature bath unit to move back and forth through rotation of the rotating shaft.
Optionally, a front and rear sliding guide rail clamping strip is further arranged at the bottom of the warm bath unit, and the front and rear sliding guide rail clamping strip is clamped on a sliding guide rail fixed on the surface of the supporting mechanism to slide in a front and rear directional mode.
Optionally, the light-emitting detection unit includes a transmitter housing, a transmission window is disposed at the bottom of the transmitter housing, the transmitter is longitudinally disposed in the transmitter housing, a fixed sliding plate is disposed on the rear end face of the transmitter housing, a horizontal sliding rail clamping strip is disposed on the back of the fixed sliding plate, and a fixed block fixedly connected to the synchronous belt is disposed on the upper portion of the fixed sliding plate.
Optionally, the detector comprises a single photon counter, a photomultiplier tube, a silicon photo cell, or a silicon photodiode.
Optionally, a lens is further disposed at the front end of the detector.
Optionally, the exciter can emit red exciting light of 600-700 nm.
The technical scheme of the utility model has the following advantages:
according to the light-activated chemical detection system provided by the embodiment, the temperature bath unit can provide a constant temperature bath, so that manual operation is reduced; in addition, further, through the reasonable setting of each part structure, make the compact structure of system, the water bath unit is through setting up stable removal around the hold-in range realization of lower part, and detecting element realizes the level through setting up in the hold-in range of upper portion again and controls stable removal, combines together through horizontal motion and orifice plate module seesaw for advance a kind and detect more smoothly inseparable, improved detecting module's degree of automation, shortened detection cycle.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic structural diagram of a laser detection module according to the present invention;
FIG. 3 is a schematic diagram of the structure of an orifice plate support module according to the present invention;
FIG. 4 is a schematic view of the reading unit structure of the present invention.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
Example 1
The present embodiment provides a light-activated chemiluminescence detection system, as shown in fig. 1 to 4, including: the device comprises a supporting mechanism 1 arranged at the bottom of the detection system and a temperature bath unit 2 arranged at the upper part of the supporting mechanism, wherein the temperature bath unit 2 realizes the warehousing and the warehousing of the temperature bath unit through a front-back movement mechanism; the pore plate 21 is arranged in the warm bath unit 2 and comprises a plurality of transverse and longitudinal pores; the luminescence detection moving unit 3 is provided with two vertical supporting frames 31, the supporting frames 31 are arranged at two sides of the warm bath unit 2, a horizontal unit moving plate 39 is arranged between the vertical supporting frames 31, rotating shafts are respectively arranged at two ends of the horizontal unit moving plate 39, a synchronous belt 22 is arranged on the horizontal unit moving plate, and a horizontal sliding rail 35 is arranged at the lower part of the horizontal unit moving plate 39; the luminescence detection unit 4 drives the luminescence detection unit to move horizontally left and right through a synchronous belt 36 and a horizontal sliding rail 35 of the luminescence detection moving unit 3, the luminescence detection unit 4 is provided with an exciter 41 and a detector 42, and laser emitted by the exciter 41 can be emitted into a corresponding hole of the orifice plate 21 through the movement of the luminescence detection moving unit 3. The detector receives an optical signal generated after a sample to be detected is excited, and collects the received optical signal; the power box 5 is provided at the rear of the detector.
The back and forth movement mechanism comprises a rotating shaft fixedly arranged on the supporting mechanism 1 and a synchronous belt 22 fixedly connected with the bottom of the temperature bath unit 2, and the synchronous belt 22 drives the temperature bath unit 2 to move back and forth through the rotation of the rotating shaft.
The bottom of the warm bath unit 2 is also provided with a front and back sliding guide rail clamping strip which is clamped on a sliding guide rail 23 fixed on the surface of the supporting mechanism 1 to slide in a front and back directional manner. The front-back movement unit drives the temperature bath unit 2 to move front and back, and the pore plate is conveyed to the luminescence detection unit to be read in the front-back direction.
The light-emitting detection unit comprises an emitter shell 43, a transmission window is arranged at the bottom of the emitter shell 43, an exciter 41 is longitudinally arranged in the emitter shell 43, a fixed sliding plate 39 is arranged on the rear end face of the emitter shell 43, a horizontal sliding rail clamping strip is arranged on the back of the fixed sliding plate, and a fixed block 38 fixedly connected with a synchronous belt is arranged on the upper portion of the fixed sliding plate 39. The device is used for receiving optical signals generated after a sample to be detected is excited and collecting and processing the received optical signals;
the exciter 32 in the embodiment can emit red exciting light of 600-700 nm. The detector 34 comprises a single photon counter, photomultiplier tube, silicon photocell, or silicon photodiode.
When the device works, a sample to be subjected to temperature bath is placed in any hole of the pore plate 21, the pore plate is placed on the temperature bath unit 2, the temperature bath unit 2 is moved into a bin by the front-back movement mechanism, after the temperature bath is finished, the temperature bath unit 2 moves back and forth to find the hole position of the sample to be detected by exciting the horizontal movement of the detection device, the sample to be detected is excited by the exciter 32 of the reading device, and the detection unit performs photon counting.
Furthermore, a lens can be arranged at the front end of the detector.
The detection mode of the utility model combines the horizontal movement of the luminescence detection moving unit with the front and back movement of the orifice plate module, so that the sample introduction and the detection are smoother and more compact.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the utility model.
Claims (7)
1. An optical laser chemiluminescence detection system, comprising:
the supporting mechanism is arranged at the bottom of the detection system;
the temperature bath unit is arranged at the upper part of the supporting mechanism and realizes the warehousing and the delivery of the temperature bath unit through a front-back movement mechanism;
the pore plate is arranged in the warm bath unit and comprises a plurality of transverse and longitudinal pores;
the light-emitting detection moving unit is provided with two vertical supporting frames which are arranged at two sides of the warm bath unit, a horizontal unit moving plate is arranged between the vertical supporting frames, two ends of the horizontal unit moving plate are respectively provided with a rotating shaft, a synchronous belt is arranged on the rotating shafts, and the lower part of the horizontal unit moving plate is provided with a horizontal sliding rail;
the light-emitting detection unit is driven by a synchronous belt and a horizontal sliding rail of the light-emitting detection moving unit to move horizontally, the light-emitting detection unit is provided with an exciter and a detector, laser emitted by the exciter can be emitted into a corresponding hole of the pore plate through the movement of the light-emitting detection moving unit, and the detector receives light signals generated after a sample to be detected is excited and collects the received light signals.
2. The optical laser chemiluminescence detection system of claim 1, wherein the forward and backward movement mechanism comprises a rotation shaft fixedly arranged on the support mechanism, and a synchronous belt fixedly connected with the bottom of the temperature bath unit, and the synchronous belt drives the temperature bath unit to move forward and backward through rotation of the rotation shaft.
3. The optical laser chemiluminescence detection system of claim 2, wherein a front and rear sliding guide rail clamping strip is further arranged at the bottom of the warm bath unit and clamped on a sliding guide rail fixed on the surface of the support mechanism to realize front and rear directional sliding.
4. The photo-laser chemiluminescence detection system according to claim 1, wherein the luminescence detection unit comprises an emitter housing, the bottom of the emitter housing is provided with an emission window, the emitter is longitudinally and fixedly arranged in the emitter housing, a fixed sliding plate is arranged on the rear end face of the emitter housing, a horizontal sliding rail clamping strip is arranged on the back of the fixed sliding plate, and a fixed block fixedly connected with the synchronous belt is arranged on the upper portion of the fixed sliding plate.
5. The photo-laser chemiluminescence detection system of claim 1, wherein the detector comprises a single photon counter, a photomultiplier tube, a silicon photo cell, or a silicon photodiode.
6. The photo-laser chemiluminescence detection system according to claim 1, further comprising a lens at the front end of the detector.
7. The photo-laser chemiluminescence detection system according to claim 1, wherein the exciter is capable of emitting 600-700 nm red excitation light.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122490172.XU CN216208534U (en) | 2021-10-15 | 2021-10-15 | Optical laser chemiluminescence detection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122490172.XU CN216208534U (en) | 2021-10-15 | 2021-10-15 | Optical laser chemiluminescence detection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216208534U true CN216208534U (en) | 2022-04-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122490172.XU Ceased CN216208534U (en) | 2021-10-15 | 2021-10-15 | Optical laser chemiluminescence detection system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216208534U (en) |
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2021
- 2021-10-15 CN CN202122490172.XU patent/CN216208534U/en not_active Ceased
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
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| IW01 | Full invalidation of patent right |
Decision date of declaring invalidation: 20230303 Decision number of declaring invalidation: 560019 Granted publication date: 20220405 |