CN216062126U - Platelet-rich plasma extraction equipment - Google Patents

Abstract

The present invention relates to a platelet rich plasma extraction device, comprising: a clean air supply device configured to include a cabinet provided with an air filter and an air outlet; the push injection device is placed in the cabinet body, and air flow formed in the cabinet body flows through the outer surface of the push injection device, wherein the push injection device comprises a push injection main body and a push injection end driven by the push injection main body; the extraction device comprises a communicating piece, a first syringe and a second syringe which are communicated through the communicating piece; the bolus control device controls a bolus end of the bolus device through a bolus main body of the bolus device; the shooting device is used for sending the shot images to the injection control device after shooting the first injector; the injection control device controls the injection end of the injection device to push the first injector according to the image sent by the shooting device so that the content of the first injector is transferred into the second injector through the communicating piece, and therefore platelet-rich plasma is extracted from blood contained in the first injector.

Description

Platelet-rich plasma extraction equipment

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a platelet-rich plasma extraction device.

Background

After centrifugation, the blood is separated into a Platelet-Poor Plasma (PPP) layer, a Platelet-Rich Plasma (PRP) layer and a red blood cell layer from the top to the bottom. Among them, PRP has the effects of accelerating wound healing and repairing cartilage damage, reducing the formation of surgical scars and promoting cartilage regeneration, and thus is widely used in the medical field. However, in the prior art, PRP is usually extracted by two times of whole blood centrifugation, the first centrifugation is used for obtaining plasma including PPP and PRP, and the second centrifugation is used for obtaining PRP, and the extraction process is generally performed by medical personnel who are trained professionally and using a plurality of medical consumables such as test tubes and syringes, which has a problem of high requirement on operators. In addition, PRP is an intermediate layer after blood centrifugation and is easily disturbed, so even if the PRP is operated by a medical staff trained by professionals, the extraction quality of PRP is unstable and even extraction fails due to factors which are difficult to avoid, such as unstable holding.

Accordingly, there is a need in the art for an extraction device for extracting stable platelet rich plasma.

SUMMERY OF THE UTILITY MODEL

The present invention aims to provide a platelet rich plasma extraction device that can solve at least some of the above problems.

According to an aspect of the present invention, there is provided a platelet rich plasma extraction apparatus including: a clean air supply device configured to include a cabinet provided with an air filter and an air outlet to form an air flow from the air filter to the air outlet within the cabinet; a bolus device disposed within a cabinet of the clean air supply device and having an airflow formed within the cabinet flowing over an exterior surface of the bolus device, wherein the bolus device is configured to include a bolus body and a bolus end driven by the bolus body to move relative to the bolus body; an extraction device configured to include a communication member, a first syringe and a second syringe detachably and hermetically connected to both ends of the communication member to be communicated with each other through the communication member, wherein the extraction device is mounted to an outer surface of a bolus body of the bolus device and the first syringe abuts against a bolus end of the bolus device; the device comprises a bolus control device, a control device and a control device, wherein the bolus control device is in communication connection with a bolus body of the bolus device so as to control a bolus end of the bolus device through the bolus body of the bolus device; the shooting device is arranged on the inner side of the cabinet body of the clean air supply device, is opposite to the first injector and is in communication connection with the bolus control device so as to send the shot images to the bolus control device after shooting the first injector; the bolus control device controls a bolus end of the bolus device to push the first syringe to transfer the content of the first syringe into the second syringe through the communication piece according to the image sent by the shooting device, so that the platelet-rich plasma is extracted from the blood contained in the first syringe.

Compared with the prior art, the platelet-rich plasma extraction equipment has the advantages that the extraction device is fixed and pushed by the injection device, the labor intensity of workers is reduced, the extraction efficiency is improved, the stability of the extraction device in the extraction process is improved, and the injection end of the injection device can push the extraction device at a constant speed, so that the extraction stability is further improved. In addition, with the push injection device and the extraction device equipartition set up in clean air feeding device, guaranteed the cleanliness factor of extraction process to the microbial contamination risk in the extraction process has greatly been avoided. Finally, through communication connection's shooting device, controlling means and the main part of injecting, can be monitored according to the shooting of the first syringe of image pair that the shooting device sent by controlling means to the main part is injected in order to control to inject in the corresponding control, and then control and draw the process, has further alleviateed manual intervention, has improved and has drawed convenience and stability.

Preferably, the bolus control device is designed to control the push speed and/or the bolus time of the bolus end of the bolus device via the bolus body of the bolus device.

Preferably, the bolus control device is integrated within a bolus body of the bolus device.

Preferably, the first syringe is configured to be arranged in a vertical direction, and a projection of the camera on a vertical plane covers a projection of the first syringe on the vertical plane.

Preferably, a clamping piece for clamping the first injector is arranged on the outer surface of the injection main body of the injection device.

Preferably, the communication of the extraction device is configured as a three-way valve.

Preferably, the extraction device is configured to further include a waste liquid collection container, and the waste liquid collection container, the first syringe, and the second syringe are respectively connected to three ends of the three-way valve.

Preferably, an air volume control device electrically connected to the air filter is arranged on the outer side of the cabinet body.

Preferably, the clean air supply apparatus is configured to further include a cabinet door coupled to the cabinet, wherein the cabinet door is designed as a transparent door.

Additional features and advantages of the utility model will be set forth in part in the description which follows, and in part will be apparent to those having ordinary skill in the art upon examination of the following, or may be learned from the practice of the utility model.

Drawings

Embodiments of the utility model are described in detail below with reference to the attached drawing figures, wherein:

fig. 1 is a schematic diagram of a platelet rich plasma extraction device according to the present invention.

Description of reference numerals:

10-a platelet rich plasma extraction device; 11-clean air supply means; 111-a cabinet body; 112-a cabinet door; 113-air volume control device; 114-an air filter; 12-a bolus device; 121-bolus injection; 122-bolus end; 123-a clamp; 13-an extraction device; 131-a communication member; 132-a first syringe; 133-a second syringe; 134-a waste liquid collection container; 14-a bolus control device; 15-shooting device.

Detailed Description

Referring now to the drawings, an illustrative version of the disclosed platelet rich plasma extraction device will be described in detail. Although the drawings are provided to present some embodiments of the utility model, the drawings are not necessarily to scale of particular embodiments, and certain features may be exaggerated, removed, or partially sectioned to better illustrate and explain the present disclosure. The position of some components in the drawings can be adjusted according to actual requirements on the premise of not influencing the technical effect. The appearances of the phrase "in the drawings" or similar language in the specification are not necessarily referring to all drawings or examples.

Certain directional terms used hereinafter to describe the drawings, such as "inner", "outer", "above", "below", and other directional terms, will be understood to have their normal meaning and refer to those directions as they normally relate to when viewing the drawings. Unless otherwise indicated, the directional terms described herein are generally in accordance with conventional directions as understood by those skilled in the art.

The terms "first," "second," and the like, as used herein, do not denote any order, quantity, or importance, but rather are used to distinguish one element from another.

As used herein, the terms "joined," "connected," and the like, are intended to encompass both components which are indirectly joined together through intervening layers (e.g., adhesives, welds, etc.) or intermediate members (e.g., connectors, transitions, etc.), and components which are directly joined together without any intervening layers (e.g., adhesives, welds, etc.) or intermediate members (e.g., connectors, transitions, etc.).

Fig. 1 shows by way of example a platelet rich plasma extraction device 10 of the present invention. The platelet rich plasma extraction device 10 in this example can be used to extract PRP from blood and can reduce the risk of microbial infection while improving extraction stability during extraction. The platelet-rich plasma extraction apparatus 10 of the present invention may include a clean air supply device 11, a bolus device 12, an extraction device 13, a bolus control device 14, and a camera 15.

Specifically, the clean air supplying apparatus 11, such as an ultra clean bench, may include a cabinet 111, and the cabinet 111, such as the top of the cabinet 111, may be provided with an air filter 114 for filtering and sucking air and an air outlet which may be provided at the bottom of the cabinet 111, so that when the air filter 114 is powered on, a clean air flow, such as a vertical air flow, may be formed from the air filter 114 flowing through the inside of the cabinet 111 to flowing out from the air outlet. The air filter 114 and the air outlet may also be disposed on other opposite sides of the cabinet 111, so that the air filter 114 and the air outlet may form clean air flow flowing through the injection device 12 and the extraction device 13. An air volume control device 113 electrically connected to the air filter 114 may be provided at an outer side of the cabinet 111 to control a suction speed of the air filter 114 when power is applied, thereby controlling an air flow rate and an air flow volume of the vertical air flow passing through the inside of the cabinet 111. In addition, a front side, i.e., a side facing an operator, of the cabinet 111 may be provided with an operation opening, where a cabinet door 112 movable with respect to the cabinet 111 may be disposed, and the cabinet door 112 may cooperate with the cabinet 111 to close or open an inner space of the cabinet 111. Preferably, the cabinet door 112 may be a transparent door such as a glass door, so that an operator outside the cabinet 111 may observe the extraction condition inside the cabinet via the glass door when the cabinet door 112 moves relative to the cabinet 111 to close the cabinet 111, thereby improving convenience in use. It should be noted that the supporting structure such as the rollers and the like which can be disposed at the bottom of the cabinet 111 can refer to the clean air supplying apparatus 11 in the related art, and will not be described in the present embodiment.

The injection device 12 may be disposed in the cabinet 111 of the clean air supply device 11, so that the air flow formed in the cabinet 111 of the clean air supply device 11 can flow over the outer surface of the injection device 12, thereby forming a clean and sterile operating environment around the injection device 12. Accordingly, the projection of air filter 114 onto a horizontal plane should cover the projection of bolus 12 onto a horizontal plane. Bolus device 12 may include a bolus body 121 and a bolus end 122. Wherein bolus body 121 of bolus device 12 may include at least a motor and a drive mechanism coupled to the motor and bolus end 122 of bolus device 12 such that movement of the motor is transmitted to bolus end 122 via the drive mechanism to cause bolus body 121 to drive bolus end 122 to move relative to bolus body 121. In addition, a holder 123 for holding the extraction device 13 may be formed on an outer surface of the bolus body 121 of the bolus device 12, and the bolus end 122 of the bolus device 12 may be movable relative to the holder 123. Alternatively, the clamping member 123 may be designed as a clamping claw or a clamping groove.

The bolus control device 14 may be in wired communication with the bolus body 121 of the bolus device 12, such as a motor, such as a universal serial bus connection, or in an untrusted communication connection, such as a bluetooth connection, for controlling the start and stop of the bolus end 122 of the bolus device 12, or for further controlling the bolus rate and/or bolus time of the bolus end 122 of the bolus device 12. Alternatively, the bolus control device 14 may be disposed inside or outside the cabinet 111 of the clean air supply device 11 as a separate structure from the bolus device 12. Preferably, the bolus control device 14 may be integrated within the bolus body 121 of the bolus device 12, thereby reducing the footprint within the cabinet 111 of the clean air supply 11. Alternatively, bolus control device 14 may include a circuit board structure built into bolus body 121 of bolus device 12 and a display and control buttons electrically connected to the circuit board and located on an outer surface of bolus body 121 of bolus device 12. Alternatively, the bolus device 12 may be a bolus pump.

The extracting apparatus 13 may include a communication member 131, and a first syringe 132 and a second syringe 133 detachably and hermetically connected to both ends of the communication member 131 to communicate with each other through the communication member 131. The conical head of the first syringe 132 may be connected to a needle assembly to collect the desired blood, and then the first syringe 132 with the blood therein may be centrifuged to stratify the components of the blood in the first syringe 132. The components in first syringe 132 are then transferred in layers to second syringe 133 as needed to extract the desired PRP from the components in first syringe 132.

Alternatively, the communication member 131 may be a three-way valve, and the extraction device 13 may further include a waste liquid collection container 134 such as a waste liquid collection bag, so that three ends of the three-way valve may be connected to the waste liquid collection container 134, the first syringe 132, and the second syringe 133, respectively. Accordingly, the three-way valve may include a three-way spool provided with a passage and a rotary piston that can control the rotation of the three-way spool, and by controlling the rotary piston to different positions, two of three structures connected to the three-way valve may be communicated, such as communicating the waste liquid collection container 134 with the first syringe 132, or communicating the waste liquid collection container 134 with the second syringe 133, or communicating the first syringe 132 with the second syringe 133, as desired.

Here, the extracting device 13 may be installed on the outer surface of the bolus body 121 of the bolus device 12, so that the clean air flow formed in the cabinet 111 of the clean air supplying device 11 also flows through the extracting device 13, thereby the whole extracting action of the extracting device 13 is performed in a clean and sterile operating environment. Furthermore, the plunger of the first syringe 132 may abut the bolus end 122 of the bolus device 12, such that when the bolus end 122 of the bolus device 12 is driven, it pushes the plunger of the first syringe 132 in motion, causing the contents of the first syringe 132 to be pushed out of the first syringe 132 and transferred via the communication member 131 into the second syringe 133 or the waste fluid collection container 134. During this process, no manual bolus is required, greatly reducing the manual labor intensity required, and the stability of the extraction process can be greatly improved via a constant speed push of the bolus end 122 of the bolus device 12.

The photographing device 15 is disposed inside the cabinet 111 of the clean air supplying device 11 to be disposed opposite to the first syringe 132 to be able to photograph the first syringe 132. The camera 15 may be in wired communication connection or wireless communication connection with the bolus control device 14, so as to send the captured image obtained by capturing the first injector 132 to the bolus control device 14, and the bolus control device 14 analyzes the extraction process based on the received image information and the preset algorithm, so as to control the motor in the bolus device 12, and then control the pushing of the bolus end 122 of the bolus device 12 to the first injector 132.

Alternatively, the first syringe 132 is arranged along the vertical direction, the highest point of the camera 15 in the vertical direction is not lower than the first syringe 132 and the lowest point of the camera 15 in the vertical direction is not higher than the first syringe 132, that is, the projection of the camera 15 on the vertical plane covers the projection of the first syringe 132 on the vertical plane, so that the camera 15 can horizontally shoot the first syringe 132 without tilting the scale on the first syringe 132, and the accurate judgment of the extraction process by the bolus control device 14 for the analysis of the shot image can be facilitated.

Illustratively, the conical head of the first syringe 132 is held down and the opening of the second syringe 133 is held in a left facing arrangement, as shown. A first syringe 132 having a volume of 30 ml may be selected and the first syringe 132 removed from the three-way valve to collect a desired volume of blood, such as 30 ml, and another, sized, and trimmed syringe may be selected to draw in the same volume of water. The conical heads of the first syringe 132 and the balancing syringe are sealed and then placed into centrifugal tubes of a centrifuge with matched sizes, and the centrifuge is carried out for 10 minutes at the rotation speed of 3500 rpm, at the moment, the blood in the centrifuged first syringe 132 is layered into PPP, PRP and red blood cells from top to bottom.

The air filter 114 of the clean air supply device 11 is opened to form a vertical clean air flow, the cabinet door 112 of the clean air supply device 11 is opened, the centrifuged first syringe 132 is mounted to the bolus device 12 located in the cabinet 111 of the clean air supply device 11, and the first syringe 132 is clamped by the clamp 123 of the bolus device 12 and fixed with respect to the bolus main body 121 of the bolus device 12. Then, the three-way valve, the second syringe 133 and the waste liquid collecting container 134 are placed in the cabinet 111 of the clean air supplying apparatus 11, the waste liquid collecting container 134 and the second syringe 133 are connected to both ends of the three-way valve, respectively, and the waste liquid collecting container 134 and the second syringe 133 are conducted to close the port thereof to be connected to the first syringe 132, and the three-way valve is connected to the first syringe 132 in this posture, thereby completing the mounting of the extracting apparatus 13 to the pushing apparatus 12.

Then, before the extraction action starts, the shooting device 15 is turned on to shoot the first injector 132, and the shot image is sent to the bolus control device 14, and the bolus control device 14 can determine the scale of the plunger of the first injector 132 and the position and the volume of each component in different colors or gray scales according to different colors or gray scales in the image, and determine the bolus volume according to the obtained volume. If the lowest layer of red blood cells in first syringe 132 is determined to be 13.5 ml, bolus control device 14 may determine that the bolus has a volume of 12.5 ml.

The camera 15 shoots the first syringe 132 in real time or periodically, adjusts the three-way valve to connect the first syringe 132 with the waste liquid collecting container 134 and disconnect the first syringe 132 from the second syringe 133, controls the bolus control device 14 to activate the bolus device 12, and closes the cabinet door 112 of the clean air supply device 11. The bolus end 122 of the bolus device 12 pushes the plunger of the first syringe 132 to transfer the red blood cells in the first syringe 132 into the waste fluid collection container 134 until the bolus control device 14 determines from the image from the camera 15 that the plunger of the first syringe 132 has been pushed to the designated scale, the bolus control device 14 controls the bolus device 12 to stop, at which time only PPP and PRP are stored in the first syringe 132, and only 1 ml of red blood cell layer is left as a mixing segment with PRP and is regarded as PRP.

The cabinet door 112 of the clean air supply apparatus 11 is opened, and the first syringe 132 is detached from the three-way valve and removed from the holder 123 of the bolus apparatus 12, thereby taking the first syringe 132 out of the clean air supply apparatus 11. Then, the first syringe 132 is centrifuged at 3500 rpm for 10 minutes, and the contents of the first syringe 132 after the second centrifugation are separated into PPP and PRP from top to bottom.

The second centrifuged first syringe 132 is clamped by the clamp 123 of the bolus device 12 and fixed to the bolus body 121 of the bolus device 12. Next, the first syringe 132 is connected to a three-way valve connected to the waste liquid collection container 134 and the second syringe 133, and the three-way valve is rotated to connect the first syringe 132 and the second syringe 133 and disconnect the first syringe 132 and the second syringe 133 from the waste liquid collection container 134.

The bolus control device 14 determines the scale of the plunger of the first syringe 132 according to the image captured by the capturing device 15, and calculates the average platelet recovery rate of 70% according to the separation technology level, so that PRP 4-5 times as large as that of the platelet rich plasma enrichment system needs to be prepared, and the bolus control device 14 can set the volume of PRP to be bolus-injected to 4.67 ml. The push injection device 12 is controlled by the push injection control device 14 to be started, and the cabinet door 112 of the clean air supply device 11 is closed. The bolus end 122 of the bolus device 12 pushes the plunger of the first injector 132 to transfer the PRP in the first injector 132 to the second injector 133 until the bolus control device 14 determines from the image from the camera 15 that the plunger of the first injector 132 has been pushed to the designated scale, and the bolus control device 14 controls the bolus device 12 to stop, at which time only PPP is stored in the first injector 132 and the PR P in the first injector 132 is transferred to the second injector 133. The extraction of the PRP can be completed by opening the cabinet door 112 of the clean air supplying apparatus 11, detaching the second syringe 133 from the three-way valve and sealing or connecting the needle assembly.

In yet another example, the extraction action is the same as in the previous example from the preparation phase until the transfer of the layer of red blood cells in the first syringe 132 into the waste collection container 134. After the layer of red blood cells in the first syringe 132 is transferred to the waste liquid collection container 134, the first syringe 132 and the second syringe 133 are connected to each other by the rotary three-way valve, and disconnected from the waste liquid collection container 134. The bolus end 122 of the bolus 12 may then be controlled directly by the bolus control device 14 to continue pushing the first syringe 132, while transferring 4.67 milliliters of PRP in the first syringe 132 into the second syringe 133. The extraction of the PRP can be completed by opening the cabinet door 112 of the clean air supplying apparatus 11, detaching the second syringe 133 from the three-way valve and sealing or connecting the needle assembly.

It should be understood that any combination of the operation steps of the extraction device in this embodiment to extract PRP should fall within the protection scope of the present invention.

It should be understood that although the description is in terms of various embodiments, not every embodiment includes only a single embodiment, and such description is for clarity purposes only, and those skilled in the art will recognize that the embodiments described herein may be combined as suitable to form other embodiments, as will be appreciated by those skilled in the art.

The above description is only an exemplary embodiment of the present invention, and is not intended to limit the scope of the present invention. Any equivalent alterations, modifications and combinations can be made by those skilled in the art without departing from the spirit and principles of the utility model.

Claims (9)

1. A platelet rich plasma extraction device (10), the platelet rich plasma extraction device (10) comprising:

a clean air supply device (11) configured to include a cabinet (111), the cabinet (111) being provided with an air filter (114) and an outlet to form an airflow from the air filter (114) to the outlet within the cabinet (111);

a bolus device (12) placed within a cabinet (111) of the clean air supply device (11) and an airflow formed within the cabinet (111) flows over an outer surface of the bolus device (12), wherein the bolus device (12) is configured to include a bolus body (121) and a bolus end (122) driven by the bolus body (121) to move relative to the bolus body (121);

an extraction device (13) configured to include a communication member (131), a first syringe (132) and a second syringe (133) detachably and hermetically connected to both ends of the communication member (131) to be conducted to each other through the communication member (131), wherein the extraction device (13) is mounted to an outer surface of a bolus body (121) of the bolus device (12) and the first syringe (132) abuts against a bolus end (122) of the bolus device (12);

a bolus control device (14) communicatively coupled with a bolus body (121) of the bolus device (12) to control a bolus end (122) of the bolus device (12) via the bolus body (121) of the bolus device (12);

a photographing device (15) disposed inside a cabinet (111) of the clean air supply device (11) and opposite to the first syringe (132) and communicatively connected with the bolus control device (14) to transmit a photographed image to the bolus control device (14) after photographing the first syringe (132);

wherein the bolus control device (14) controls the bolus end (122) of the bolus device (12) to push the first syringe (132) to transfer the content of the first syringe (132) into the second syringe (133) through the communication piece (131) according to the image sent by the shooting device (15), so as to extract platelet-rich plasma from the blood contained in the first syringe (132).

2. Platelet-rich plasma extraction device (10) according to claim 1, wherein the bolus control means (14) is designed to control the bolus speed and/or the bolus time of a bolus end (122) of the bolus device (12) via a bolus body (121) of the bolus device (12).

3. The platelet rich plasma extraction device (10) of claim 2, wherein the bolus control device (14) is integrated within a bolus body (121) of the bolus device (12).

4. The platelet-rich plasma extraction apparatus (10) according to claim 1, wherein the first syringe (132) is configured to be arranged in a vertical direction, and a projection of the camera (15) on a vertical plane covers a projection of the first syringe (132) on the vertical plane.

5. The platelet rich plasma extraction device (10) of claim 1, wherein a holder (123) for holding the first syringe (132) is provided on an outer surface of the bolus body (121) of the bolus device (12).

6. The platelet rich plasma extraction apparatus (10) of claim 1, wherein the communication (131) of the extraction device (13) is configured as a three-way valve.

7. The platelet-rich plasma extraction apparatus (10) according to claim 6, wherein the extraction device (13) is configured to further include a waste liquid collection container (134), the first syringe (132), and the second syringe (133) being respectively connected to three ends of the three-way valve.

8. The platelet rich plasma extraction device (10) according to claim 1, wherein an air volume control means (113) electrically connected to the air filter (114) is provided to an outside of the cabinet (111).

9. The platelet-rich plasma extraction apparatus (10) according to claim 1, wherein the clean air supply device (11) is configured to further comprise a cabinet door (112) cooperating with the cabinet body (111), wherein the cabinet door (112) is designed as a transparent door.

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