CN215745175U - Multifunctional thrombin rinsing tank - Google Patents

Multifunctional thrombin rinsing tank Download PDF

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Publication number
CN215745175U
CN215745175U CN202121427674.1U CN202121427674U CN215745175U CN 215745175 U CN215745175 U CN 215745175U CN 202121427674 U CN202121427674 U CN 202121427674U CN 215745175 U CN215745175 U CN 215745175U
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China
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tank body
rinsing
liquid
tank
thrombin
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CN202121427674.1U
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Chinese (zh)
Inventor
方翱
张理火
周涛
李兆勇
张军东
吴剑英
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Shanghai Haohai Biological Technology Co ltd
Shanghai Jianhua Fine Biological Products Co ltd
Shanghai Likangrui Bioengineering Co ltd
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Shanghai Haohai Biological Technology Co ltd
Shanghai Jianhua Fine Biological Products Co ltd
Shanghai Likangrui Bioengineering Co ltd
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Application filed by Shanghai Haohai Biological Technology Co ltd, Shanghai Jianhua Fine Biological Products Co ltd, Shanghai Likangrui Bioengineering Co ltd filed Critical Shanghai Haohai Biological Technology Co ltd
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Abstract

The utility model discloses a multifunctional thrombin rinsing tank which comprises a tank body, a stirring device and a support frame; a manhole is arranged at the top of the tank body, and a tank cover is arranged on the manhole; the stirring device is arranged in the tank body and is opposite to the manhole; the supporting frame is connected to the bottom of the tank body and used for supporting the tank body to be stable; a spraying device is arranged on the inner side of the tank body; a liquid inlet for filling rinsing liquid is formed in the top of the tank body; the top of the tank body is also provided with a plurality of liquid clamping interfaces; a liquid outlet for discharging rinsing liquid is arranged at the lower part of the side surface of the tank body; a discharge hole is formed in the bottom of the tank body; the tank body is also provided with a temperature sensor interface and a pH meter interface; a weighing device is arranged on the support frame; a rotating wheel for discharging the rinsing liquid in the tank body is arranged in the liquid outlet. The rinsing tank disclosed by the utility model is simple in structure, can realize multiple times of rinsing by single equipment, shortens the production line, and improves the space utilization rate and the production efficiency.

Description

Multifunctional thrombin rinsing tank
Technical Field
The utility model relates to the technical field of pharmaceutical equipment, in particular to a multifunctional thrombin rinsing tank, and particularly relates to a thrombin barium salt precipitation rinsing tank.
Background
The rinsing tank is a common equipment for pharmaceutical production, and mainly stirs materials by a stirring shaft driven by a motor, and quickly mixes the sediment with the rinsing liquid by adding the rinsing liquid to remove impurities contained in the sediment.
The existing rinsing process generally adopts a mode of rinsing and precipitating for many times, and the mode needs a plurality of devices, has complex process and large occupied space of equipment; and the rinsed precipitate is separated from the rinsing liquid, so that the precipitate loss and the incomplete removal of the rinsing liquid are easily caused, and the yield and the rinsing effect are influenced.
The barium salt is precipitated and rinsed and then enters a redissolution process, for example, the precipitation weight, temperature and pH are difficult to control, which is not beneficial to redissolution and the quality of a final product.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a multifunctional thrombin rinsing tank, which is used for realizing multiple rinsing by using the same equipment and solving the problems of loss, incomplete separation, difficulty in controlling the weight, temperature and pH of a rinsing system and the like during the separation of a rinsed precipitate and a rinsing liquid.
The rinsing tank disclosed by the utility model is simple in structure, can realize multiple times of rinsing by single equipment, shortens the production line, and improves the space utilization rate and the production efficiency.
The utility model is realized by the following technical scheme:
a multifunctional thrombin rinsing tank is characterized by comprising a tank body, a stirring device and a support frame; a manhole is arranged at the top of the tank body; a tank cover is arranged on the manhole; the stirring device is arranged in the tank body and is opposite to the manhole; the support frame is connected to the bottom of the tank body and used for supporting the tank body to be stable; a spraying device is arranged on the inner side of the tank body; a liquid inlet for filling rinsing liquid is formed in the top of the tank body; the top of the tank body is also provided with a plurality of liquid clamping interfaces; a liquid outlet for discharging rinsing liquid is formed in the lower part of the side surface of the tank body; a discharge hole is formed in the bottom of the tank body; the tank body is also provided with a temperature sensor interface and a pH meter interface; the support frame is provided with a weighing device; and a rotating wheel for discharging the rinsing liquid in the tank body is arranged in the liquid outlet. Specifically, the stirring device is used for fully stirring and rinsing the rinsing object when the thrombin precipitation rinsing is carried out. Specifically, the multifunctional thrombin rinsing tank disclosed by the utility model has the functions of washing impurities, removing supernatant, separating out materials and controlling the weight, temperature and pH of a product, is beneficial to the quality control of the product, realizes multiple times of rinsing by using single equipment, shortens a production line, and improves the space utilization rate and the production efficiency. Preferably, the number of the support frames is three, the three support frames are fixedly arranged at the bottom of the tank body in a triangular shape, and the support effect on the tank body (namely the whole rinsing tank) is achieved. The weighing device is used for weighing the whole rinsing tank, the coefficient of the weighing device is reset to zero when rinsing is carried out, and then rinsing materials (sediment) and rinsing liquid are added. The spraying device is used for spraying cleaning liquid to clean the interior of the tank body before rinsing. The manhole is arranged on one side of the top of the tank body, and the stirring device is arranged on the other side of the top of the tank body and is opposite to the manhole.
Furthermore, the manhole is connected with the tank cover through a hinge, a flange surface, a sealing ring and a fixing nut. The manhole refers to a perforated structure for people to get in and out of equipment for installation, maintenance and safety inspection. In particular, the manhole is used for feeding materials into the rinsing tank when the rinsing tank is in operation.
Furthermore, the stirring device comprises a variable frequency motor, a transmission shaft and a stirring paddle; the variable frequency motor fixed set up with the top of the jar body, the transmission shaft rotate and set up in the jar body, the one end of transmission shaft is connected on the variable frequency motor, the other end extends to in the jar body and with the stirring rake is connected. Inverter motor be used for the drive the transmission shaft rotates, the transmission shaft drive the stirring rake rotates, makes rinsing material (sediment) in the jar body carry out abundant rinsing.
Furthermore, a plurality of the liquid clamping ports are respectively used for connecting a filter (respirator), a pressure gauge or a safety valve.
Further, the top of the tank body is also provided with an observation window.
Furthermore, a lighting lamp is arranged in the observation window. The rinsing materials in the tank body can be clearly seen through the observation window and the illuminating lamp.
Further, a jacket is arranged around the outside of the tank body; the jacket is provided with a water filling port for adding water between the tank body and the jacket. Specifically, the clamping sleeve is arranged outside the tank body and is wrapped; on one hand, the jacket can protect the tank body; on the other hand, hot water or cooling water can be filled between the jacket and the tank body according to the requirement of the temperature during rinsing, and the material liquid in the tank body and the pipe body can be heated or cooled, so that the effect of auxiliary adjustment of the rinsing temperature is achieved. Preferably, the jacket can be made of stainless steel.
Further, the rotating wheel comprises a liquid suction pipe, a liquid discharge pipe and a rotating wheel; the liquid suction pipe is connected to the liquid discharge pipe and communicated with the liquid discharge pipe; the pipette is arranged in the tank body and is used for sucking rinsing liquid in the tank body; the liquid discharge pipe is rotatably arranged on the tank body and the clamping sleeve; the rotating wheel is connected to the liquid discharge pipe and is positioned on the outer side of the jacket. Specifically, when rinse liquid is added, the rotating wheel is rotated to enable the orifice of the pipette to face upwards, so that the rinse liquid enters the pipette and exhausts air in the pipette; when stirring and rinsing, the rotating wheel is rotated to enable the orifice of the liquid suction pipe to face downwards, so that the phenomenon that rinsing matters (namely sediment) or air enter the liquid suction pipe during stirring is avoided; when rinse liquid is discharged after rinsing is finished, the rotating wheel is rotated to enable the pipe orifice of the liquid suction pipe to be positioned on the surface of a rinsed object (namely a sediment) without contacting with the sediment, then a valve outside the tank body is opened, and supernatant liquid is discharged by utilizing a siphon principle; during the supernatant fluid discharge period, the positions of the liquid level in the tank body, the sediment and the pipette nozzle are observed through the observation window and the illuminating lamp, and the pipette is adjusted by continuously rotating the rotating wheel, so that the nozzle is prevented from exposing the liquid level and entering air until no supernatant fluid is discharged. The liquid suction pipe and the liquid discharge pipe can be made of stainless steel 316.
Compared with the prior art, the multifunctional thrombin rinsing tank has the beneficial effects that:
(1) the multifunctional thrombin rinsing tank is simple in structure; this multi-functional fibrin ferment rinsing jar drops into sediment (rinsing thing) and rinsing liquid, accomplishes the rinsing back, from the discharge of liquid outlet discharge supernatant of jar body side lower part, remains the sediment of tank bottoms, drops into the rinsing liquid from the inlet department again, and rinsing many times so realizes single equipment rinsing many times, has shortened production line, has improved space utilization and production efficiency.
(2) According to the multifunctional thrombin rinsing tank, the rotating wheel is arranged in the liquid outlet at the lower part of the side surface of the tank body, the rotating wheel comprises the liquid suction pipe, the liquid discharge pipe and the rotating wheel, and rinsing liquid can be discharged as much as possible by rotating the rotating wheel to adjust the position of the pipe orifice of the liquid suction pipe in the tank body without losing sediment at the bottom of the tank body.
(3) The multifunctional thrombin rinsing tank has the function of controlling the weight, the temperature and the pH of a rinsing system, and is more beneficial to the production of the next procedure and the quality control of a final product.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic diagram of the multi-functional thrombin rinse tank of the present invention;
FIG. 2 is a top view of the multi-functional thrombin rinse tank of the present invention.
In the figure: 1 tank body, 2 stirring devices, 3 support frames, 4 manholes, 5 tank covers, 6 spraying devices, 7 liquid inlets, 8 liquid clamping ports, 9 liquid discharging ports, 10 material discharging ports, 11 temperature sensor ports, 12pH meter ports, 13 weighing devices, 14 rotating wheels, 15 observation windows, 16 clamping sleeves, 21 variable frequency motors, 22 transmission shafts, 23 stirring paddles, 141 pipette, 142 liquid discharging pipes, 143 rotating wheels and 144 valves.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the utility model, its application, or uses. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
As shown in fig. 1-2, the multifunctional thrombin rinsing tank is characterized by comprising a tank body 1, a stirring device 2 and three support frames 3; a manhole 4 is arranged on one side of the top of the tank body 1; a tank cover 5 is arranged on the manhole 4 (the manhole 4 is connected with the tank cover 5 through a hinge, a flange surface, a sealing ring and a fixing nut); the stirring device 2 is arranged at the other side of the tank body 1, and the stirring device 2 and the manhole 4 are oppositely arranged; the support frame 3 is fixedly connected to the bottom of the tank body 1 and is used for supporting the tank body 1 to be stable; a spraying device 6 is arranged on the inner side of the tank body 1; a liquid inlet 7 for filling rinsing liquid is formed in the top of the tank body 1; the top of the tank body 1 is also provided with a plurality of liquid clamping ports 8 (the liquid clamping ports 8 are used for connecting a filter, a pressure gauge or a safety valve and the like); a liquid outlet 9 for discharging rinsing liquid is arranged at the lower part of the side surface of the tank body 1; a discharge hole 10 is formed in the bottom of the tank body 1; the tank body 1 is also provided with a temperature sensor interface 11 and a pH meter interface 12; the supporting frame 3 is provided with a weighing device 13; a rotating wheel 14 for discharging the rinsing liquid in the tank body 1 is arranged in the liquid outlet 9.
8. Preferably, the multifunctional thrombin rinsing tank further comprises an observation window 15, wherein the observation window 15 is arranged at the top of the tank body 1, and an illuminating lamp is further arranged in the observation window 15. Preferably, a jacket 16 is further arranged outside the tank body 1, the jacket 16 is arranged around the side surface of the tank body 1, and a water injection port for adding water between the tank body 1 and the jacket is arranged on the jacket 16. In the multifunctional thrombin rinsing tank of the embodiment 1, the stirring device 2 comprises a variable frequency motor 21, a transmission shaft 22 and a stirring paddle 23; variable frequency motor 21 fixed set up with the top of jar body 1, transmission shaft 22 rotate and set up in jar body 1, the one end of transmission shaft 22 is connected on variable frequency motor 21, the other end extend to jar body 1 in and with stirring rake 23 is connected.
As shown in fig. 1, the above-mentioned rotation wheel 14 includes a liquid suction pipe 141, a liquid discharge pipe 142 and a rotation wheel 143; the liquid suction pipe 141 is connected to and communicated with the liquid discharge pipe 142; the pipette 141 is arranged inside the tank body 1, and the pipette 141 is used for sucking the rinsing liquid in the tank body 1; the drain pipe 142 is rotatably arranged on the tank body 1 and the jacket 16; the runner 143 is connected to the drain pipe 142 and located outside the jacket 16.
When the multifunctional thrombin rinsing tank is actually used, the operation process is as follows:
(1) when in use, firstly, acid/alkali injection water is sprayed into the tank body 1 through the spraying device 6, and the tank body 1 is cleaned;
(2) after the cleaning in the step (1), introducing steam into the tank body 1 for sterilization, and after the sterilization, recovering the temperature in the tank body 1 to the room temperature;
(3) putting the material (sediment) to be rinsed into the tank body 1 from the manhole 4, and then adding rinsing liquid into the tank body 1 from the liquid inlet 7 (or adding the rinsing liquid from the discharge port 10 at the bottom of the tank body 1 to avoid generating foam); then, the variable frequency motor 21 is started to drive the stirring paddle 23 to rotate, so that the precipitate and the rinsing liquid are uniformly mixed and are fully rinsed; after rinsing, the variable frequency motor 21 is closed, standing is carried out for natural sedimentation and layering, and supernatant of the upper layer and sediment of the lower layer are formed;
(4) by rotating the rotating wheel 143 so that the pipette 141 is on the sedimentation surface without contacting the sediment, the valve 144 outside the rotating wheel 143 is opened to discharge the supernatant in the tank 1 out of the tank 1 through the pipette 141 and the drain pipe 142; continuously adjusting the position of the orifice of the pipette 141 during the period of discharging the supernatant liquid to avoid exposing the liquid level of the supernatant liquid and keep the orifice of the liquid washing tube 141 not in contact with the sediment; the supernatant in the tank body 1 is completely discharged through the siphon action; when the position of the pipette 141 is adjusted by the rotating wheel 143, the illumination lamp can be turned on to observe the sediment and the supernatant in the tank body 1 through the observation window 15, so that the pipe orifice of the liquid washing pipe 141 does not leak the supernatant liquid level and is not contacted with the sediment;
(5) the weight of the rinsing system is controlled by the weighing device 13; the temperature of the rinsing system is controlled by connecting a temperature sensor in the interface of the temperature sensor 11 and heating water or cooling water into the jacket 16; a pH meter is connected into a pH meter interface 12 to monitor the pH value of the rinsing system; when the temperature sensor detects that the temperature of the rinsing system is lower, hot water can be filled between the jacket 16 and the tank body 1 from a water filling port on the jacket 16 to assist in raising the temperature of the rinsing system; otherwise, when the rinsing temperature is higher, cooling water is added; when the pH value of the rinsing system is monitored to be higher, a proper amount of dilute hydrochloric acid can be added into the tank body 1 through the manhole 4, so that the rinsing system is kept neutral; otherwise, when the pH value of the rinsing system is monitored to be lower, a proper amount of sodium hydroxide solution can be added into the tank body 1 through the manhole 4, so that the rinsing system is kept neutral;
(6) after rinsing, the precipitate is transferred from the discharge port 10 to the next process, i.e., the precipitate rinsing process is completed.
The multifunctional thrombin rinsing tank disclosed by the utility model realizes multiple times of rinsing by using the same equipment and solves the problems of loss, incomplete separation, difficulty in controlling the weight, temperature and pH of a rinsing system and the like when a rinsed precipitate is separated from a rinsing liquid.
The above-mentioned preferred embodiments of the present invention are provided for illustration only and not for the purpose of limiting the utility model. Obvious variations or modifications of the present invention are within the scope of the present invention.

Claims (8)

1. A multifunctional thrombin rinsing tank is characterized by comprising a tank body (1), a stirring device (2) and a support frame (3); a manhole (4) is arranged at the top of the tank body (1); a tank cover (5) is arranged on the manhole (4); the stirring device (2) is arranged in the tank body (1), and the stirring device (2) and the manhole (4) are oppositely arranged; the support frame (3) is connected to the bottom of the tank body (1) and is used for supporting the tank body (1) to be stable; a spraying device (6) is arranged on the inner side of the tank body (1); a liquid inlet (7) for filling rinsing liquid is formed in the top of the tank body (1); the top of the tank body (1) is also provided with a plurality of liquid clamping interfaces (8); a liquid outlet (9) for discharging rinsing liquid is formed in the lower part of the side surface of the tank body (1); a discharge hole (10) is formed in the bottom of the tank body (1); the tank body (1) is also provided with a temperature sensor interface (11) and a pH meter interface (12); the supporting frame (3) is provided with a weighing device (13); a rotating wheel (14) for discharging the rinsing liquid in the tank body (1) is arranged in the liquid discharging port (9).
2. The multifunctional thrombin rinsing tank as claimed in claim 1, wherein the manhole (4) is connected with the tank cover (5) through a hinge, a flange face, a sealing ring and a fixing nut.
3. The multifunctional thrombin rinsing tank as claimed in claim 1, wherein the stirring device (2) comprises a variable frequency motor (21), a transmission shaft (22) and a stirring paddle (23); inverter motor (21) fixed set up in the top of the jar body (1), transmission shaft (22) rotate and set up in the jar body (1), the one end of transmission shaft (22) is connected on inverter motor (21), the other end extends to in the jar body (1) and with stirring rake (23) are connected.
4. The multifunctional thrombin rinsing pot as claimed in claim 1, wherein said liquid interfaces (8) are respectively used for connecting a filter, a pressure gauge or a safety valve.
5. The multifunctional thrombin rinsing pot according to claim 1, wherein a viewing window (15) is further arranged at the top of the pot body (1).
6. The multifunctional thrombin rinsing pot according to claim 5, wherein an illuminating lamp is arranged in the observation window (15).
7. The multifunctional thrombin rinsing pot according to claim 1, wherein a jacket (16) is arranged around the outside of the pot body (1); the jacket (16) is provided with a water filling port for adding water between the tank body (1) and the jacket (16).
8. The multifunctional thrombin rinsing pot according to claim 7, wherein the rotating wheel (14) comprises a pipette (141), a drain pipe (142) and a rotating wheel (143); the liquid suction pipe (141) is connected to the liquid discharge pipe (142) and communicated with the liquid discharge pipe; the pipette (141) is arranged inside the tank body (1), and the pipette (141) is used for sucking rinsing liquid in the tank body (1); the liquid discharge pipe (142) is rotatably arranged on the tank body (1) and the jacket (16); the rotating wheel (143) is connected to the drain pipe (142) and is positioned outside the jacket (16).
CN202121427674.1U 2021-06-25 2021-06-25 Multifunctional thrombin rinsing tank Active CN215745175U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121427674.1U CN215745175U (en) 2021-06-25 2021-06-25 Multifunctional thrombin rinsing tank

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121427674.1U CN215745175U (en) 2021-06-25 2021-06-25 Multifunctional thrombin rinsing tank

Publications (1)

Publication Number Publication Date
CN215745175U true CN215745175U (en) 2022-02-08

Family

ID=80102260

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121427674.1U Active CN215745175U (en) 2021-06-25 2021-06-25 Multifunctional thrombin rinsing tank

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Country Link
CN (1) CN215745175U (en)

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