CN214986234U - Automatic packaging system of kit for detection - Google Patents

Automatic packaging system of kit for detection Download PDF

Info

Publication number
CN214986234U
CN214986234U CN202121278475.9U CN202121278475U CN214986234U CN 214986234 U CN214986234 U CN 214986234U CN 202121278475 U CN202121278475 U CN 202121278475U CN 214986234 U CN214986234 U CN 214986234U
Authority
CN
China
Prior art keywords
reagent
sample adding
packaging system
base
automatic packaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202121278475.9U
Other languages
Chinese (zh)
Inventor
王勤
宋倩
徐文飞
叶盛
郑祥钊
王昕�
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Lifereal Biotechnology Co ltd
Original Assignee
Hangzhou Lifereal Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Lifereal Biotechnology Co ltd filed Critical Hangzhou Lifereal Biotechnology Co ltd
Priority to CN202121278475.9U priority Critical patent/CN214986234U/en
Application granted granted Critical
Publication of CN214986234U publication Critical patent/CN214986234U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model discloses an automatic packaging system of a detection kit, which comprises a base, a rotating platform and a sample adding needle tray with a notch; a linear displacement module is arranged on the base; a plurality of stations are distributed on the circumference of the rotating platform along the rotating direction, a plurality of reagent box placing blocks are arranged on the rotating platform, and reagent boxes with plungers are arranged in the reagent box placing blocks; a cam is arranged in the rotating platform; sample adding needles are uniformly distributed on the sample adding needle tray; the height of the sample adding needle corresponds to the position of the sample adding needle; a reagent injection module is arranged on the base; three grooves are sequentially arranged on the circumferential surface of the side edge of the cam from top to bottom, the three grooves respectively correspond to the three plungers of the kit, and the depth of each groove corresponds to the circumferential angle of the groove. The invention improves the gene detection kit with the plunger, and has the advantages of relatively higher packaging efficiency, relatively lower production cost and no limitation on the application and popularization of the gene detection kit.

Description

Automatic packaging system of kit for detection
Technical Field
The utility model relates to a medical science check out test set technical field, especially an automatic packaging system of kit for detection.
Background
The gene detection is a technology for detecting DNA through blood, other body fluids or cells, which is to take oral mucosa cells or other tissue cells dropped by a detected person, amplify the gene information, detect DNA molecular information in the cells of the detected person through specific equipment, predict the risk of the body suffering from diseases, analyze various gene conditions contained in the cells, enable people to know the own gene information, and avoid or delay the occurrence of the diseases by improving the living environment and the living habits of the people.
Since a sample used in gene detection is a biological tissue cell, it is necessary to detect a gene by performing steps such as lysis, washing, amplification, etc. on the cell and then detecting the gene by optical detection. Because different treatments are involved in each step, the sample is generally required to be treated in different steps through a plurality of devices, the detection is troublesome, and the sample is sometimes required to be transferred to different carriers when different steps are carried out, so that pollution is easily introduced in the process, and the detection precision is influenced. In order to overcome these problems, a gene detection kit is proposed, which has the following structure: comprises a box body, wherein a cracking zone and a cleaning zone which are separated by a plunger (121) are respectively arranged in the box body from top to bottom, a reaction zone is arranged below the cleaning zone, and the number of the cleaning zones is 1 or more; the plunger (121) is horizontally arranged, a plunger hole (1211) in the vertical direction is formed in the plunger (121), and a spring (122) is arranged at one end of the plunger (121). The specific contents of the kit can be found in a patent-gene detection kit with patent publication No. CN 206872836U. Based on the ingenious setting of gene detection kit, it can be used for the gene detection of integration, can not only break away from the dependence of gene detection to a large amount of equipment, promotes detection efficiency, can avoid introducing the pollution in the testing process moreover, promotes and detects the precision.
The kit needs to use a matched reagent packaging system in the reagent packaging production process, and is used for injecting and packaging the reagent into the kit.
Traditional reagent packaging system is only applicable to ordinary kit, because this gene detect reagent box inside is equipped with the plunger, it can't be directly by the simple injection reagent of application of sample equipment to lead to traditional reagent packaging system can't effectually apply to this gene detect reagent box's reagent encapsulation, influence this gene detect reagent box's encapsulation efficiency, thereby restricted its production output, improved its manufacturing cost, finally influenced this gene detect reagent box's application and popularization.
Therefore, the traditional reagent packaging system has the problems that the traditional reagent packaging system is not suitable for a gene detection kit with a plunger, the packaging efficiency is influenced, the production cost is improved, and the application and popularization are limited.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an automatic packaging system of kit for detection. The utility model discloses make the improvement to the gene detection kit who takes the plunger, can be applicable to its automatic encapsulation well, have that encapsulation efficiency is higher relatively, manufacturing cost is lower relatively, can not restrict the advantage of gene detection kit application and popularization.
The technical scheme of the utility model: an automatic packaging system of a kit for detection comprises a base, a rotating platform arranged on the base and a sample adding needle tray with a notch arranged above the rotating platform; the base is provided with a linear displacement module for driving the sample adding needle tray to move up and down; a plurality of stations are distributed on the circumference of the rotating table along the rotating direction, a plurality of reagent box placing blocks corresponding to the stations are arranged on the rotating table, and a reagent box with three plungers can be placed in each reagent box placing block; a cam is arranged in the rotating platform; sample adding needles corresponding to the positions of the reagent boxes are uniformly distributed on the sample adding needle tray; the height of each sample adding needle corresponds to the position of the sample adding needle; a reagent injection module connected with the sample adding needle is arranged on the base; three grooves are sequentially arranged on the circumferential surface of the side edge of the cam from top to bottom, the three grooves respectively correspond to the three plungers of the kit, and the depth of each groove corresponds to the circumferential angle of the groove.
In the automatic packaging system for a test kit, the groove comprises a deepest part with the deepest depth, a shallowest part with the shallowest depth and a transition part between the deepest part and the shallowest part; when the reagent box moves to a station at the deepest part of the groove, the plunger is popped up by the spring, so that a channel in the reagent box is closed, and the reagent and the sample adding needle cannot pass through the channel; when the reagent box moves to the position where the groove is the shallowest, the plunger is pushed by the cam, so that a channel in the reagent box is opened, and the reagent and the sample adding needle can penetrate into the channel.
In the automatic packaging system of the detection kit, the heights of the sampling needles, the kit and the cam at the same station correspond to each other, the cam controls the opening and closing conditions of the plunger in the kit at the station, and then the sampling needles with the corresponding heights are used for injecting the reagents with the corresponding levels.
In the automatic reagent packaging system in the reagent box, the rotary table comprises a rotary motor fixed on the base, a rotary driving motor connected with the rotary motor and a rotary table arranged on the rotary motor; the reagent box placing blocks are uniformly arranged on the rotary disc; the rotary motor drives the rotary table to rotate clockwise, and the rotary motor rotates the reagent box from the current station to the next station once.
In the automatic packaging system of the detection kit, the base is provided with a waste liquid cup mounting bracket positioned outside the rotating table; a plurality of waste liquid cup mounting holes are uniformly formed in the waste liquid cup mounting bracket; waste liquid cup mounting hole is used for placing waste liquid and collects the cup, and staff's accessible waste liquid is collected cup and is collected the liquid that application of sample needle syringe needle department dropped in real time, prevents that it from polluting this system's table surface.
In the automatic packaging system of the detection kit, the base is provided with an emergency stop switch for emergency power off and an online interface for connecting a computer.
In the automatic packaging system of the detection kit, the reagent injection module comprises a plurality of sample containers, and an injection pump and an infusion tube which are connected with the sample containers; the infusion tube is respectively connected with the sample container and the injection pump through infusion tube joints; the transfusion tube is connected with the sample adding needle through a pipeline joint.
The automatic packaging system of the detection kit is also provided with a temperature control module; the temperature control module comprises a temperature control module, a sampling needle adjusting block arranged on a sampling needle tray, a heating wire wound on the sampling needle, a circuit board for the sampling needle and a plurality of temperature probes, wherein the circuit board is arranged on the sampling needle tray and connected with the heating wire, and the temperature probes are connected with the temperature control module; the temperature probes are respectively arranged at the sample adding needle and the sample container; the sample container is provided with a heating device connected with the temperature control module; the circuit board for the sample adding needle is used for connecting the heating wire and the temperature probe, so that the assembly and disassembly are convenient; the temperature control probe acquires the current temperature in real time, and the temperature control module controls the heating devices such as the heating wires according to the current temperature and the preset temperature.
In the automatic packaging system of the kit for detection, the sampling needle adjusting block can adjust the vertical height and the horizontal position of the sampling needle, so that the sampling needle can be accurately aligned with the kit.
In the automatic packaging system of the detection kit, a linear displacement module driving motor is arranged above the linear displacement module; the linear displacement module can be a device capable of moving up and down and can adopt hydraulic, pneumatic, chain, gear and other transmission modes.
Compared with the prior art, the utility model provides an automatic packaging system of a detect-used kit that is applied to the gene detection kit of taking the plunger specially, this system drives the rotatory revolving stage of kit through setting up, fix the cam that laminates and correspond with the kit inside the revolving stage, still set up the application of sample needle that highly differs and can go up and down on the revolving stage, when the kit rotated to corresponding station, recess on the cam pushed the plunger in the reagent box or did not push in (the open and shut state of its plunger of different stations is different) to make the passageway in the reagent box communicate or close with the plunger hole on the plunger, the application of sample needle that corresponds to the height descends to the lowest and carries out the reagent application of sample after getting into the reagent box, then the revolving stage drives the kit and gets into next station and carries out the application of sample; the packaging system completely conforms to the characteristic that the opening and closing of the interior of the gene detection kit with the plunger are controlled by the plunger, and the plunger in the kit is automatically opened and closed and the corresponding reagent is filled through the mutual matching of the cam, the rotating table and the sample adding needle, so that the automatic packaging is realized, and the packaging efficiency is higher compared with that of the traditional packaging system; adopt the utility model discloses take the gene detect reagent box of plunger to carry out automatic encapsulation, its encapsulation efficiency is higher back, and corresponding just can improve its production scale, has reduced manufacturing cost on the whole, and bigger production scale and relative lower cost of generation make this gene detect reagent box can be better promote and use, bring bigger economic benefits.
Therefore, the utility model discloses make the improvement to the gene detection kit who takes the plunger, can be applicable to its automatic encapsulation well, have that encapsulation efficiency is higher relatively, manufacturing cost is lower relatively, can not restrict the advantage of gene detection kit application and popularization.
Drawings
FIG. 1 is a schematic structural diagram of an automatic packaging system of the present invention;
FIG. 2 is an enlarged view at A in FIG. 1;
FIG. 3 is an enlarged view at B in FIG. 1;
FIG. 4 is an enlarged view at C of FIG. 1;
fig. 5 is a schematic diagram of the opening and closing of the plunger of the reagent kit of the present invention;
figure 6 is a schematic view of the reagent filling line of the present invention;
FIG. 7 is a schematic diagram of the reagent encapsulation process in the kit of the present invention.
The labels in the figures are: 1-sample adding needle tray, 2-sample adding needle, 21-pipeline joint, 3-sample adding needle adjusting block, 4-sample adding needle circuit board, 5-linear displacement module, 6-linear displacement module driving motor, 7-temperature control module, 8-sample container, 81-infusion tube, 811-infusion tube joint, 9-injection pump, 10-rotary table, 101-kit placing block, 11-rotary table, 12-kit, 121-plunger, 1211-plunger hole, 122-spring, 123-channel, 13-cam, 14-waste liquid cup mounting bracket, 15-emergency stop switch, 16-online interface and 17-base.
Detailed Description
The following description is made with reference to the accompanying drawings and examples, but not to be construed as limiting the invention.
Examples are given. An automatic packaging system of a kit for detection, as shown in fig. 1-7, comprises a base 17, a rotating platform 10 arranged on the base 17 and a sample adding needle tray 1 with a notch arranged above the rotating platform 10; the base 17 is provided with a linear displacement module 5 for driving the sample adding needle tray 1 to move up and down; a plurality of stations are distributed on the circumference of the rotary table 10 along the rotation direction, a plurality of reagent kit placing blocks 101 corresponding to the stations are arranged on the rotary table 10, and a reagent kit 12 with three plungers 121 can be placed in each reagent kit placing block 101; a cam 13 is arranged in the rotating platform 10; sample adding needles 2 corresponding to the positions of the reagent boxes 12 are uniformly distributed on the sample adding needle tray 1; the height of each sample adding needle 2 corresponds to the position of the sample adding needle; a reagent injection module connected with the sample adding needle 2 is arranged on the base 17; three grooves are sequentially arranged on the circumferential surface of the side edge of the cam 13 from top to bottom, the three grooves respectively correspond to the three plungers 121 of the reagent kit 12, and the depth of each groove corresponds to the circumferential angle of the groove.
The groove comprises a deepest part with the deepest depth, a shallowest part with the shallowest depth and a transition part between the deepest part and the shallowest part; when the reagent box 12 moves to the station at the deepest part of the groove, the plunger 121 is ejected by the spring, so that the channel 123 in the reagent box 12 is closed, and the reagent and the sample adding needle 2 cannot pass through the channel 123; when the reagent cartridge 12 is moved to the position where the recess is at its lowest, the plunger 121 is pushed by the cam, which causes the channel 123 in the reagent cartridge 12 to open and the reagent and the loading needle 2 can penetrate into the channel 123.
The height of the sampling needle 2, the reagent box 12 and the cam 13 on the same station are all corresponding to each other, the cam 13 controls the opening and closing condition of the plunger 121 in the reagent box 12 under the station, and then the sampling needle 2 with the corresponding height injects the reagent with the corresponding level.
The rotating platform 10 comprises a rotating motor fixed on the base 17, a rotating driving motor connected with the rotating motor and a rotating disk 11 arranged on the rotating motor; the reagent box placing blocks 101 are uniformly arranged on the rotary disc 11; the rotary motor drives the rotary table to rotate clockwise, and the rotary motor rotates the reagent kit 12 from the current station to the next station once.
The base 17 is provided with a waste liquid cup mounting bracket 14 positioned outside the rotating platform 10; a plurality of waste liquid cup mounting holes are uniformly formed in the waste liquid cup mounting bracket 14; the waste liquid cup mounting hole is used for placing a waste liquid collecting cup.
The base 17 is provided with an emergency stop switch 15 for emergency power-off and an online interface 16 for connecting a computer.
The reagent injection module comprises a plurality of sample containers 8, an injection pump 9 connected with the sample containers 8 and an infusion tube 81; the infusion tube 81 is respectively connected with the sample container 8 and the injection pump 9 through an infusion tube joint 811; the infusion tube 81 is connected with the sample adding needle 2 through the pipeline joint 21.
A temperature control module is arranged; the temperature control module comprises a temperature control module 7, a sampling needle adjusting block 3 arranged on a sampling needle tray 1, a heating wire wound on the sampling needle 2, a circuit board 4 for the sampling needle and arranged on the sampling needle tray 1 and connected with the heating wire, and a plurality of temperature probes connected with the temperature control module 7; the temperature probes are respectively arranged at the sample adding needle 2 and the sample container 8; the sample container 8 is provided with a heating device connected with the temperature control module 7; the circuit board 4 for the sample adding needle is used for connecting the heating wire and the temperature probe, so that the disassembly and the assembly are convenient; the temperature control probe acquires the current temperature in real time, and the temperature control module 7 controls the heating devices such as the heating wires according to the current temperature and the preset temperature.
The sampling needle adjusting block 3 can adjust the vertical height and the horizontal position of the sampling needle 2.
A linear displacement module driving motor 6 is arranged above the linear displacement module 5; the linear displacement module 5 is a device capable of moving up and down and consists of a linear guide rail and a ball screw.

Claims (8)

1. An automatic packaging system of a kit for detection is characterized in that: comprises a base (17), a rotating platform (10) arranged on the base (17) and a sample adding needle tray (1) with a gap arranged above the rotating platform (10); the base (17) is provided with a linear displacement module (5) for driving the sample adding needle tray (1) to move up and down; a plurality of stations are distributed on the circumference of the rotary table (10) along the rotation direction, a plurality of reagent kit placing blocks (101) corresponding to the stations are arranged on the rotary table (10), and a reagent kit (12) with three plungers (121) can be placed in each reagent kit placing block (101); a cam (13) is arranged in the rotating platform (10); sample adding needles (2) corresponding to the positions of the reagent boxes (12) are uniformly distributed on the sample adding needle tray (1); the height of each sample adding needle (2) corresponds to the position of the sample adding needle; a reagent injection module connected with the sample adding needle (2) is arranged on the base (17); three grooves are sequentially arranged on the circumferential surface of the side edge of the cam (13) from top to bottom, the three grooves respectively correspond to the three plungers (121) of the reagent kit (12), and the depth of each groove corresponds to the circumferential angle of the groove.
2. The automatic packaging system for a test kit according to claim 1, wherein: the grooves include a deepest depth, a shallowest depth and a transition therebetween.
3. The automatic packaging system for a test kit according to claim 1, wherein: the rotating table (10) comprises a rotating motor arranged on the base (17), a rotating driving motor connected with the rotating motor and a rotating disc (11) arranged on the rotating motor; the reagent box placing blocks (101) are uniformly arranged on the rotary disc (11).
4. The automatic packaging system for a test kit according to claim 1, wherein: a waste liquid cup mounting bracket (14) positioned outside the rotating platform (10) is arranged on the base (17); a plurality of waste liquid cup mounting holes are uniformly formed in the waste liquid cup mounting support (14).
5. The automatic packaging system for a test kit according to claim 1, wherein: the base (17) is provided with an emergency stop switch (15) for emergency power-off and an online interface (16) for connecting a computer.
6. The automatic packaging system for a test kit according to claim 1, wherein: the reagent injection module comprises a plurality of sample containers (8), an injection pump (9) connected with the sample containers (8) and an infusion tube (81); the infusion tube (81) is respectively connected with the sample container (8) and the injection pump (9) through an infusion tube joint (811); the infusion tube (81) is connected with the sample adding needle (2) through a pipeline joint (21).
7. The automatic packaging system for a test kit according to claim 1, wherein: a temperature control module is arranged; the temperature control module comprises a temperature control module (7), a sampling needle adjusting block (3) arranged on a sampling needle tray (1), a heating wire wound on the sampling needle (2), a circuit board (4) for the sampling needle, which is arranged on the sampling needle tray (1) and connected with the heating wire, and a plurality of temperature probes connected with the temperature control module (7); the temperature probes are respectively arranged at the sampling needle (2) and the sample container (8).
8. The automatic packaging system for a test kit according to claim 1, wherein: and a linear displacement module driving motor (6) is arranged on the linear displacement module (5) arranged on the base (17).
CN202121278475.9U 2021-06-09 2021-06-09 Automatic packaging system of kit for detection Active CN214986234U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121278475.9U CN214986234U (en) 2021-06-09 2021-06-09 Automatic packaging system of kit for detection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121278475.9U CN214986234U (en) 2021-06-09 2021-06-09 Automatic packaging system of kit for detection

Publications (1)

Publication Number Publication Date
CN214986234U true CN214986234U (en) 2021-12-03

Family

ID=79130817

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121278475.9U Active CN214986234U (en) 2021-06-09 2021-06-09 Automatic packaging system of kit for detection

Country Status (1)

Country Link
CN (1) CN214986234U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113443184A (en) * 2021-06-09 2021-09-28 杭州遂真生物技术有限公司 Automatic reagent packaging system in reagent box and packaging method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113443184A (en) * 2021-06-09 2021-09-28 杭州遂真生物技术有限公司 Automatic reagent packaging system in reagent box and packaging method thereof

Similar Documents

Publication Publication Date Title
CN107290562B (en) A kind of automatic sample handling system for the detection of sample cell high throughput
US5151184A (en) Fluid collecting and dispensing system
US5262049A (en) Fluid collecting and dispensing system
CN214986234U (en) Automatic packaging system of kit for detection
WO2022110575A1 (en) Luminescence measurement device and method capable of continuous measurement of multiple reaction cups
CN104459174B (en) A kind of Portable type full-automatic biochemistry analyzer
CN201152848Y (en) Bionic intelligent type blood rheogeniometer
WO2022110574A1 (en) Liquid injection and suction device for measurement chamber
CN109406801A (en) Sample analyser and its sample collection and distribution method
CN101806810A (en) Multi-reagent needle biochemistry analyzer
CN102033133A (en) Automatic precision loading device
CN106980025A (en) The former test tube automatic sampling apparatus in Three Degree Of Freedom multitube position
CN108333381A (en) A kind of digestion instrument automatic sampling device
CN106811405A (en) The liquid-way system and its reagent delivery method of gene sequencer
CN106428659A (en) Multi-position medicine dispenser
CN113443184B (en) Automatic packaging system and method for reagents in reagent box
CN205176041U (en) Excrement and urine autoanalyzer
CN112098666B (en) Cleaning system for full-automatic chemiluminescence immunoassay analyzer
CN205941131U (en) Machinery cantilever and use cell film -making preprocessor of this structure
CN217466952U (en) Full-automatic thrombelastogram instrument
CN105910962A (en) Full-automatic in-vitro transdermal vertical dispersion testing device
CN207133304U (en) A kind of automatic sample handling system for the detection of sample cell high flux
CN215297150U (en) Multi-reaction-cup continuous measurement light-emitting measurement device
CN213032560U (en) Test tube storage device capable of intelligently identifying test tubes
CN102890159A (en) Sampling system for automatically identifying samples and sampling method for sampling system

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant