CN214953559U - Rapid immunohistochemical detection equipment - Google Patents

Abstract

The utility model discloses a quick immunohistochemical check out test set, comprises a box bod, the box body includes cistern, slide glass fixed station, baffle, through-hole, takes out groove and unit groove, slide glass fixed station and cistern interval distribution are in the inside of box body, the baffle evenly sets up the inside at the slide glass fixed station, the through-hole has all been seted up to the both sides wall of slide glass fixed station, the through-hole is kept away from the one end of slide glass fixed station and is extended to the lateral wall of cistern, take out the groove and set up in the below of cistern, the utility model relates to a histochemical check out test set technical field. This quick immunohistochemical check out test set through being provided with a plurality of baffles, through-hole and slide glass fixed station, can be with the section location in the slide glass fixed station, and the through-hole of seting up is convenient for the liquid that flows out in the experimentation and accomplish the abluent liquid outflow after the test, does not accumulate and forms the dirt to the cleanliness of device has been promoted, is convenient for take out cleanly.

Description

Rapid immunohistochemical detection equipment

Technical Field

The utility model belongs to the technical field of the group ization check out test set, concretely relates to quick immunohistochemical check out test set.

Background

Immunohistochemical staining is widely used in biomedical research at present, is an irreplaceable diagnostic means in clinical cases, and is mainly based on the principle that an antigen is specifically combined with an antibody, and a chemical reaction is utilized to enable a color developing agent (fluorescein, enzyme, metal ions and isotopes) for marking the antibody to develop color so as to determine the antigens (polypeptides and proteins) in tissue cells, and the tissue cells are subjected to positioning, qualitative and quantitative research.

However, in the current experimental process, the reaction time is long, so that various methods for improving the experimental process appear in the development process of histochemistry, wherein the polymer (enzyme or protein) technology is particularly prominent, wherein the protein marker using magnetic beads as carriers has the characteristics of being attracted by magnetic force in addition to the function of polymer, and at present, the characteristic cannot be utilized in the incubation process of histochemistry, so that the magnetic beads as carriers cannot exert the greatest advantages. And in the experimental process, the sample needs to be continuously taken and placed for heating, cleaning and other operations, so that the problems of sample pollution, uneven reagent distribution and the like are caused.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a quick immunohistochemical check out test set to solve the current characteristic that can't utilize magnetic attraction and lead to using the magnetic bead to mark as unable its the biggest superiority of performance as the carrier, and experiment operation can cause the problem that the sample pollutes and reagent distributes unevenly in the experimentation.

In order to achieve the above object, the utility model provides a following technical scheme: a rapid immunohistochemical detection device comprises a box body, wherein the box body comprises a liquid tank, a glass slide fixing table, a partition plate, through holes, a drawing groove and unit grooves, the glass slide fixing table and the liquid tank are distributed in the box body at intervals, the partition plate is uniformly arranged in the glass slide fixing table, the through holes are formed in the two side walls of the glass slide fixing table, one end, away from the glass slide fixing table, of each through hole extends to the side wall of the liquid tank, the drawing groove is formed below the liquid tank, the top of the drawing groove is communicated with the bottom of the liquid tank, the unit grooves are formed in the side wall of the box body, a heating unit is arranged in each unit groove, a water tank mechanism is arranged in each drawing groove and comprises a water tank, a tank box and a first handle, the water tank is formed in the tank box and is movably connected with the drawing groove, an electromagnetic module is arranged on one side, away from the unit grooves, of the box body, the electromagnetic module is movably connected with the box body.

Preferably, the heating unit includes hot plate, second handle, baffle and temperature sensor, temperature sensor evenly distributed is at the roof of hot plate, temperature sensor and controller electric connection, the lateral wall and the baffle fixed connection of hot plate, baffle and unit groove looks block.

Preferably, the electromagnetic module comprises a die holder, an electromagnet and a magnetic bead groove, the electromagnet is fixedly installed at the top of the die holder and electrically connected with the controller, the magnetic bead groove is formed in the electromagnet, and the electromagnetic module is movably connected with the box body.

Preferably, the second handle is mounted on a side of the partition plate away from the heating plate.

Preferably, the first handle is fixedly installed on the outer side wall of the groove box.

Preferably, the magnetic beads are arranged in the magnetic bead grooves.

Preferably, the top wall of the box body is movably hinged with a box cover.

Compared with the prior art, the utility model, following beneficial effect has:

(1) this quick immunohistochemical check out test set, through being provided with a plurality of baffles, through-hole and slide glass fixed station, can be with section location in the slide glass fixed station, and the through-hole of seting up is convenient for the abluent liquid outflow after the experiment in-process flows and the completion test, do not accumulate and form the dirt, thereby the cleanliness of device has been promoted, and simultaneously, need abluent in the experiment in-process can directly wash on the slide glass fixed station, avoid a large amount of sections to wash simultaneously and cause the pollution, and the imbibition passes through the cistern and takes out the groove and arrange into the basin, be convenient for take out cleanly, also can prevent the dry piece of section with water in the experimentation, keep the humid environment of experiment.

(2) This quick immunohistochemical check out test set, through set up to dismantlement formula structure between with electromagnetic module and heating element and the box body, and the heating element is close apart from the slide glass fixed station, the rate of heating can promote, simultaneously when using arbitrary magnetic bead product, accessible electromagnetic module provides decurrent magnetic attraction, and can change magnetic force and magnetism frequency of inhaling and make magnetic bead mark product subside fast and the destination protein produces the reaction, and through control panel to the control of frequency, make it still keep appropriate relative motion, can be abundant with the destination protein collision and take place the reaction. Thereby allowing the reaction to be more rapid and accurate than conventional reactions with only heat.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic structural view of the box body of the present invention;

fig. 3 is a schematic structural view of the heating unit of the present invention;

fig. 4 is a schematic structural diagram of the electromagnetic module of the present invention;

FIG. 5 is a schematic structural view of the sink mechanism of the present invention;

in the figure: 1-box body, 11-liquid groove, 12-glass slide fixing table, 13-clapboard, 14-through hole, 15-drawing groove, 16-unit groove, 2-box cover, 3-display panel, 4-controller, 5-water groove mechanism, 51-water groove, 52-groove box, 53-first handle, 6-heating unit, 61-heating plate, 62-second handle, 63-clapboard, 64-temperature sensor, 7-electromagnetic module, 71-die holder, 72-electromagnet, 73-magnetic bead groove.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides the following technical solutions: a rapid immunohistochemical detection device comprises a box body 1, wherein the box body 1 comprises a liquid groove 11, a glass slide fixing table 12, a partition plate 13, through holes 14, a drawing groove 15 and unit grooves 16, the glass slide fixing table 12 and the liquid groove 11 are distributed in the box body 1 at intervals, the partition plate 13 is uniformly arranged in the glass slide fixing table 12, the through holes 14 are formed in two side walls of the glass slide fixing table 12, one end, far away from the glass slide fixing table 12, of each through hole 14 extends to the side wall of the liquid groove 11, the drawing groove 15 is arranged below the liquid groove 11, the top of the drawing groove 15 is communicated with the bottom of the liquid groove 11, the unit grooves 16 are formed in the side wall of the box body 1, a heating unit 6 is arranged in each unit groove 16, a water groove mechanism 5 is arranged in the drawing groove 15, each water groove mechanism 5 comprises a water groove 51, a groove box 52 and a first handle 53, the groove 51 is arranged in the groove box 52, and the drawing groove 15 are movably connected, the electromagnetic module 7 is arranged on one side of the box body 1 far away from the unit groove 16, the electromagnetic module 7 is movably connected with the box body 1, the heating unit 6 comprises a heating plate 61, a second handle 62, a partition plate 63 and a temperature sensor 64, the temperature sensor 64 is uniformly distributed on the top wall of the heating plate 61, the temperature sensor 64 is electrically connected with the controller 4, the side wall of the heating plate 61 is fixedly connected with the partition plate 63, the partition plate 63 is clamped with the unit groove 16, the electromagnetic module 7 comprises a die holder 71, an electromagnet 72 and a magnetic bead groove 73, the electromagnet 72 is fixedly arranged on the top of the die holder 71, the electromagnet 72 is electrically connected with the controller 4, the magnetic bead groove 73 is arranged inside the electromagnet 72, the electromagnetic module 7 is movably connected with the box body 1, the second handle 62 is arranged on one side of the partition plate 63 far away from the heating plate 61, the first handle 53 is fixedly arranged on the outer side wall of the box 52, and magnetic beads are arranged inside the magnetic bead groove 73, top wall activity hinge of box body 1 has lid 2, through being provided with a plurality of baffles 13, through-hole 14 and slide glass fixed station 12, can be with section location in slide glass fixed station 12, and the through-hole 14 of seting up is convenient for the abluent liquid outflow after the experiment process flows out and the completion test, do not accumulate and form the dirt, thereby the cleanliness of device has been promoted, and simultaneously, can directly wash on slide glass fixed station 12 when needing abluent in the experiment process, avoid a large amount of sections to wash simultaneously and cause the pollution, and the imbibition passes through cistern 11 and takes out in the groove 15 arranges into basin 51, be convenient for take out cleanly, also can add water in the experiment process and prevent the dry piece of section, keep the moist environment of experiment.

During operation, put the magnetic bead into magnetic bead groove 73 inside, then drive electromagnetic module 7 work through controller 4, make electromagnetic module 7 produce decurrent magnetic attraction, and change electromagnet 72 simultaneously, the magnetic force and the magnetism frequency of inhaling of magnetic bead, thereby make the product in the magnetic bead mark slice subside fast and the destination protein produces the reaction, at the in-process of control, through the control to electromagnet 72 magnetism frequency of inhaling, make the magnetic bead keep appropriate relative motion, thereby make magnetic force and the inside destination protein collision of section react, obtain more rapid and accurate result than conventional reaction, the operation precision of device has been promoted.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. A rapid immunohistochemical detection device, comprising a box body (1), characterized in that: the glass slide fixing platform is characterized in that the box body (1) comprises a liquid tank (11), a glass slide fixing platform (12), a partition plate (13), through holes (14), a drawing groove (15) and unit grooves (16), the glass slide fixing platform (12) and the liquid tank (11) are distributed in the box body (1) at intervals, the partition plate (13) is uniformly arranged in the glass slide fixing platform (12), the through holes (14) are formed in two side walls of the glass slide fixing platform (12), one end, far away from the glass slide fixing platform (12), of each through hole (14) extends to the side wall of the liquid tank (11), the drawing groove (15) is formed below the liquid tank (11), the top of the drawing groove (15) is communicated with the bottom of the liquid tank (11), the unit grooves (16) are formed in the side wall of the box body (1), a heating unit (6) is arranged in the unit grooves (16), and a water tank mechanism (5) is arranged in the drawing groove (15), the water tank mechanism (5) comprises a water tank (51), a tank box (52) and a first handle (53), wherein the water tank (51) is arranged inside the tank box (52), the tank box (52) is movably connected with a drawing groove (15), one side, far away from a unit groove (16), of the box body (1) is provided with an electromagnetic module (7), and the electromagnetic module (7) is movably connected with the box body (1).

2. A rapid immunohistochemical detection device according to claim 1, wherein: heating unit (6) are including hot plate (61), second handle (62), baffle and temperature sensor (64), temperature sensor (64) evenly distributed is at the roof of hot plate (61), temperature sensor (64) and controller (4) electric connection, the lateral wall and the baffle fixed connection of hot plate (61), baffle and unit groove (16) looks block.

3. A rapid immunohistochemical detection device according to claim 2, wherein: electromagnetic module (7) include die holder (71), electromagnet (72) and magnetic bead groove (73), electromagnet (72) fixed mounting is in the top of die holder (71), electromagnet (72) and controller (4) electric connection, magnetic bead groove (73) are seted up in electromagnet (72) inside, electromagnetic module (7) and box body (1) swing joint.

4. A rapid immunohistochemical detection device according to claim 3, wherein: the second handle (62) is arranged on one side of the partition board far away from the heating plate (61).

5. A rapid immunohistochemical detection device according to claim 4, wherein: the first handle (53) is fixedly arranged on the outer side wall of the groove box (52).

6. A rapid immunohistochemical detection device according to claim 5, wherein: magnetic beads are arranged in the magnetic bead grooves (73).

7. A rapid immunohistochemical detection device according to claim 6, wherein: the top wall of the box body (1) is movably hinged with a box cover (2).

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