CN214609226U

CN214609226U - Portable temperature control device for detecting virus nucleic acid by RPA technology

Info

Publication number: CN214609226U
Application number: CN202120844377.0U
Authority: CN
Inventors: 刘少卿
Original assignee: Jiangsu Genesmile Precision Medical Technology Co ltd
Current assignee: Jiangsu Genesmile Precision Medical Technology Co ltd
Priority date: 2021-04-22
Filing date: 2021-04-22
Publication date: 2021-11-05
Anticipated expiration: 2031-04-22

Abstract

The utility model discloses a portable temperature control device for detecting virus nucleic acid by RPA technology, which comprises a box body and a box cover, wherein a sample placing frame is arranged in the box body, a sample bottle placing cavity with a plurality of stations is arranged on the sample placing frame, a refrigeration component is arranged in the box body, and the refrigeration component is used for keeping a sample bottle placed in the sample bottle placing cavity at a constant temperature; case lid one side axial rotation sets up in the top of box, and the top of case lid is provided with the display screen between two parties, and the display screen integration is on setting up the inside circuit board of case lid, and the circuit board is assembled and is used for gathering refrigeration subassembly temperature data and transmits to the display screen and show, adjust refrigeration subassembly's power supply. The utility model discloses a portable RPA technique detects temperature control device of virus nucleic acid has solved because this in-process of putting into the sample bottle repeatedly, hardly keeps the inside temperature of insulation can, and the mode of this kind of refrigeration transmission is smaller to energy consumption, and the maintenance of inside temperature is more convenient.

Description

Portable temperature control device for detecting virus nucleic acid by RPA technology

Technical Field

The utility model relates to a portable temperature control device for RPA technology detection of viral nucleic acid.

Background

The collected samples need to be transported for on-site accounting and then detected by using equipment. And certain conditions are also required for sample storage: the sample which can be detected within 24 hours can be stored at 4C; the sample which can not be detected within 24 hours is preserved at-70 ℃ or below (if the preservation condition of-70 ℃ is not available, the sample is preserved in a refrigerator at-20 ℃).

According to patent No. CN02020567465.6, a temperature control system of a nucleic acid detecting apparatus for detecting a reaction liquid is disclosed, the temperature control system comprising a plurality of temperature controllers, a pump, a plurality of reagent tanks, and flow channels connecting the plurality of reagent tanks, the pump being configured to drive the reaction liquid to flow through the flow channels so as to be alternatively accommodated in the plurality of reagent tanks; the temperature controllers correspondingly regulate the temperature of the reagent tanks to be at a denaturation temperature, an annealing temperature or an extension temperature; the reaction solution can be cyclically and sequentially contained in the plurality of reagent vessels having the denaturing temperature, the annealing temperature, and the extension temperature to perform a temperature-controlled cycle including the denaturing reaction, the annealing reaction, and the extension reaction. Different reagent tanks have preset reaction temperature, and the reaction liquid circularly and sequentially reacts in each reagent tank, so that the temperature change interval of the traditional temperature control system is saved, and the reaction time of PCR is shortened. Moreover, the reagent tank occupies a small space, and is advantageous for miniaturization of the nucleic acid detecting apparatus.

And the on-spot sample of gathering is gathered one by one, places the sample bottle in the incubator after the collection and carries out the constant temperature and deposit, but in this in-process of putting into the sample bottle repeatedly, because the interval time is shorter, consequently hardly keeps the inside temperature of incubator.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a portable RPA technique detects temperature control device of virus nucleic acid for this in-process of putting into the sample bottle repeatedly is solved, because the interval time is than short, consequently hardly keeps the problem of the inside temperature of insulation can.

In order to achieve the above object, the present invention provides the following technical solutions: a portable temperature control device for detecting virus nucleic acid by RPA technology comprises:

the sample bottle storage device comprises a box body, wherein a sample placing frame is arranged in the box body, a sample bottle placing cavity with a plurality of stations is formed in the sample placing frame, and a refrigerating assembly is arranged in the box body and is used for keeping a sample bottle placed in the sample bottle placing cavity at a constant temperature;

the case lid, case lid one side axial rotate set up in the top of box, the top of case lid is provided with the display screen between two parties, the display screen integrated in set up in on the inside circuit board of case lid, the circuit board assembled be used for gathering refrigeration subassembly temperature data and transmit extremely the display screen shows, adjusts refrigeration subassembly's power supply.

Preferably, the front face of the box cover is symmetrically and axially provided with a clamping plate in a rotating mode, and the front face of the box body is symmetrically provided with clamping grooves matched with the clamping plate in a clamping mode.

Preferably, the refrigeration assembly comprises a heat insulation plate and a refrigeration pipe, the heat insulation plate is arranged inside the box body and forms a refrigeration cavity with the bottom of the inner side of the box body, and the refrigeration pipe is arranged on the outer wall of one side of the refrigeration cavity of the heat insulation plate groove.

Preferably, the sample rack includes heat preservation panel and heat dissipation vest limit, the heat dissipation vest limit is pegged graft in the boring hole that the heat insulating board top was seted up and is extended to the refrigeration intracavity, the sample bottle place the chamber by the round hole that the heat insulating panel top was seted up and set up in the heat insulating panel to heat insulating board one side distributes and about the side lamella board that the circular hole circumference array distributes constitutes.

Preferably, the heat insulation panel is provided with a heat dissipation waistcoat column facing the heat insulation plate, the heat dissipation waistcoat column is located between every four circular holes, and the heat dissipation waistcoat column is inserted into a boring hole formed in the top of the heat insulation panel and extends into the refrigeration cavity.

Preferably, the bottom of the inner side of the sample bottle placing cavity is provided with a pressing type rebounder.

Preferably, the sample bottle placing cavity is axially and rotatably provided with a sealing cover, and the outer wall of the sealing cover, which faces one side of the port of the sample bottle placing cavity, is provided with a heat-insulating sealing ring.

Preferably, a temperature detector is arranged on the heat preservation panel and used for detecting the temperature of the space where the radiating waistcoat column and the radiating waistcoat edge are located and transmitting collected data to the circuit board.

Preferably, a storage battery is arranged in the box cover and used for supplying power to the circuit board and the refrigeration assembly, a USB interface and a power switch are arranged on the side edge of the box cover, the USB interface is assembled to be directly connected with commercial power to supplement the power supply for the storage battery, and the power switch is used for controlling the circuit to be switched on and switched off.

Preferably, the outer walls of two opposite sides of the box body are respectively connected with nylon braces.

In the technical scheme, the utility model provides a pair of portable RPA technical detection virus nucleic acid's temperature control device possesses beneficial effect: set up the bottom at the box with refrigeration subassembly, then transmit the air conditioning of making the intracavity to the upper strata utilizing heat dissipation vest post and heat dissipation vest limit to, then cool down in the space between sample rack and heat insulating board, and the sample bottle is then placed the chamber through single sample bottle and is placed, has solved because this in-process of putting into the sample bottle repeatedly, hardly keeps the inside temperature of insulation can. And the refrigeration mode and the cooling transmission mode have low energy consumption, the internal temperature is convenient to maintain, the power loss caused by the fact that the circuit board needs to repeatedly adjust the output power for keeping constant temperature is avoided, and the service life of the equipment is prolonged.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings can be obtained by those skilled in the art according to these drawings.

FIG. 1 is a schematic structural diagram of a closed state of a portable temperature control device for detecting viral nucleic acid by RPA technology according to an embodiment of the present invention;

fig. 2 is a schematic structural diagram of an open state of a temperature control device for detecting viral nucleic acid by using the portable RPA technology according to an embodiment of the present invention;

fig. 3 is a schematic structural view of a sample rack provided in an embodiment of the present invention;

fig. 4 is a schematic view showing an internal structure of a box according to an embodiment of the present invention;

fig. 5 is a schematic cross-sectional structure view of a sample bottle placing cavity provided in an embodiment of the present invention;

fig. 6 is an assembly structure diagram of the refrigeration assembly and the sample placing rack provided by the embodiment of the present invention.

Description of reference numerals:

1. a box body; 2. a sample placing rack; 43. a heat-insulating panel; 431. a heat dissipating vest post; 44. a heat dissipation waistcoat skirt; 21. a buckle plate; 22. a fastening groove; 3. a sample bottle placement chamber; 31. a side flap plate; 32. a press type rebounder; 33. sealing the cover; 4. a refrigeration assembly; 41. a heat insulation plate; 42. a refrigeration pipe; 5. a display screen; 7. a box cover; 100. a refrigeration cavity.

Detailed Description

In order to make the technical solution of the present invention better understood by those skilled in the art, the present invention will be further described in detail with reference to the accompanying drawings.

As shown in fig. 1-6, a portable temperature control device for detecting viral nucleic acid by RPA technology comprises a box 1 and a box cover 7, wherein one side of the box cover 7 is axially and rotatably disposed on the top of the box 1. In the scheme, refrigeration component 4 sets up in the bottom of box 1, then utilizes heat dissipation vest post 431 and heat dissipation vest limit 44 to transmit the air conditioning of making in the refrigeration chamber 100 to the upper strata, then cools down in the space between sample rack 2 and heat insulating board 41, and the sample bottle is then placed the chamber through single sample bottle and is carried out 3 and place, has solved because this in-process of putting into the sample bottle repeatedly, hardly keeps the inside temperature of insulation can. And the refrigeration mode and the cooling transmission mode have low energy consumption, the internal temperature is convenient to maintain, and the power loss caused by the fact that the circuit board needs to repeatedly adjust the output power for keeping constant temperature is avoided.

Furthermore, in the technical scheme provided by the utility model, the sample placing rack 2 is placed inside the box body 1, the refrigeration component 4 is positioned below the sample placing rack 2, the sample bottle placing cavity 3 with a plurality of stations is arranged on the sample placing rack 2, the sample bottle placing cavity 3 is cooled by the refrigeration component 4, thereby ensuring that the sample inside can be kept in a constant temperature environment of-4 ℃,

in the embodiment, the refrigerating assembly 4 comprises a heat insulation plate 41 and a refrigerating pipe 42, as can be seen from fig. 4, the heat insulation plate 41 is installed inside the cabinet 1 and forms the refrigerating chamber 100 with the bottom of the inside of the cabinet 1, and the refrigerating pipe 42 is installed on the outer wall of the heat insulation plate 41 on the side of the refrigerating chamber 100. The refrigerant pipe 42 operates to cool down the inside of the refrigerant chamber 100 so that the temperature inside the refrigerant chamber 100 reaches a predetermined temperature.

Further, in the above scheme, the sample placing rack 2 includes a heat preservation panel 43 and a heat dissipation waistcoat skirt 44. As can be seen from fig. 6, the heat dissipating waistcoat skirt 44 is inserted into a bored hole formed in the top of the heat shield 41 and extends into the refrigeration cavity 100. Similarly, the heat insulation panel 43 is provided with heat dissipation waistcoat columns 431 facing the heat insulation plate 41, the heat dissipation waistcoat columns 431 are located between every four round holes, and the heat dissipation waistcoat columns 431 are inserted into the bored holes formed in the top of the heat insulation panel 43 and extend into the refrigeration cavity 100. Due to the temperature conductivity of the metal, the temperature of the refrigeration cavity 100 can be quickly transferred to the heat dissipation waistcoat column 431 and the heat dissipation waistcoat edge 44, so that the temperature of the space between the heat insulation panel 43 and the heat insulation plate 41 is quickly reduced to-4 ℃, and the temperature is kept constant.

In the above embodiment, as can be seen from fig. 5, the sample bottle placing chamber 3 is composed of a circular hole formed in the top of the heat insulating panel 43 and side flap plates 31 disposed on the heat insulating panel 43 and distributed toward the heat insulating plate 41 and distributed in a circumferential array around the circular hole. The sample inserted into the sample bottle placing cavity 3 can be stored in the constant-temperature environment of-4 ℃, and the temperature is slowly diffused in the repeated opening process because each sample bottle placing cavity 3 is independent. Further, a cover 33 is hinged on the top of each sample bottle placing cavity 3, and the transparent material of the cover 33 can directly observe whether the sample bottle placing cavity 3 is used for placing a sample bottle.

It should be noted that the depth of the sample bottle placing cavity 3 is the same as the length of the sample bottle, so as to facilitate taking of the sample bottle, as can be seen from fig. 5, the bottom of the inner side of the sample bottle placing cavity 3 is provided with the pressing type rebounder 32, and the length of the telescopic column at the output end of the pressing type rebounder 32 is changed by pressing the sample bottle, so that the sample bottle can be completely located in the sample bottle placing cavity 3, and the sealing cover 33 is convenient for sealing; or to eject a portion of the sample bottle receiving chamber 3 for grasping (the push type rebounder 32 is prior art and therefore not disclosed in detail in this application).

As a further technical solution provided by the present invention, as can be known from fig. 1, the display screen 5 is disposed at the top of the box cover 7 in the middle, the display screen 5 is integrated on the circuit board disposed inside the box cover 7, and the box cover 7 is further provided with a storage battery, and the storage battery is used for providing power for the refrigeration of the refrigeration pipe 42, the circuit board operates, and the temperature detector installed on the thermal insulation panel 43 and used for detecting the temperature of the space between the thermal insulation panel 43 and the thermal insulation board 41 (the side of the box cover 7 is provided with a USB interface, which can be directly connected with 220V commercial power to supplement power for the storage battery), and the circuit board in the solution is assembled to collect the temperature data of the refrigeration component 4 and transmit the data to the display screen 5 for displaying, and adjusting the power of the refrigeration component 4. In short, the circuit board receives the data detected by the temperature detector, then transmits the data to the display screen 5 to display the temperature, and then calculates and coordinates the power supplied to the cooling tube 42, so that the cooling tube 42 is cooled.

It should be noted that the electronic components and circuit combinations in the above-mentioned embodiments are all common technical knowledge known to those skilled in the art, and therefore, are not disclosed in detail in the present application.

While certain exemplary embodiments of the present invention have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that the described embodiments may be modified in various different ways without departing from the spirit and scope of the present invention. Accordingly, the drawings and description are illustrative in nature and should not be construed as limiting the scope of the invention.

Claims

1. A portable temperature control device for detecting virus nucleic acid by RPA technology, which is characterized by comprising:

the sample bottle storage device comprises a box body (1), wherein a sample placing frame (2) is arranged in the box body (1), a sample bottle placing cavity (3) with a plurality of stations is formed in the sample placing frame (2), a refrigerating assembly (4) is arranged in the box body (1), and the refrigerating assembly (4) is used for keeping a sample bottle placed in the sample bottle placing cavity (3) at a constant temperature;

case lid (7), case lid (7) one side axial rotate set up in the top of box (1), the top of case lid (7) is provided with display screen (5) between two parties, display screen (5) integrated in set up in on the inside circuit board of case lid (7), the circuit board is assembled and is used for gathering refrigeration subassembly (4) temperature data and transmit to the power supply of display screen (5) demonstration, regulation refrigeration subassembly (4).

2. The portable temperature control device for detecting viral nucleic acid by RPA technology according to claim 1, wherein said cover (7) has a snap plate (21) symmetrically and axially rotatably disposed on the front surface thereof, and said cover (1) has snap grooves (22) symmetrically disposed on the front surface thereof for snap-fitting with said snap plate (21).

3. The portable temperature control device for detecting virus nucleic acid by RPA technology according to claim 1, wherein said refrigeration component (4) includes a thermal insulation board (41) and a refrigeration tube (42), said thermal insulation board (41) is installed inside said cabinet (1) and forms a refrigeration cavity (100) with the bottom of the inner side of said cabinet (1), said refrigeration tube (42) is installed on the outer wall of the thermal insulation board (41) facing to the refrigeration cavity (100).

4. The portable temperature control device for detecting viral nucleic acid by RPA technology according to claim 1, wherein said sample holder (2) comprises a heat-insulating panel (43) and a heat-dissipating waistcoat (44), said heat-dissipating waistcoat (44) is inserted into a bore hole formed on the top of the heat-insulating panel (41) and extends into the refrigeration cavity (100), said sample bottle holding cavity (3) is composed of a round hole formed on the top of the heat-insulating panel (43) and side flaps (31) disposed on the heat-insulating panel (43) and distributed to one side of the heat-insulating panel (41) and distributed in a circumferential array around the round hole.

5. The portable temperature control device for detecting viral nucleic acid by RPA technology as claimed in claim 4, wherein said thermal insulation panel (43) is provided with heat dissipation waistcoat columns (431) facing said thermal insulation board (41), said heat dissipation waistcoat columns (431) are located between every four said circular holes, said heat dissipation waistcoat columns (431) are inserted into the bored holes formed at the top of said thermal insulation panel (43) and extend into said refrigeration cavity (100).

6. The portable temperature control device for detecting virus nucleic acid by RPA technology as claimed in claim 4, wherein the bottom inside the sample bottle placing cavity (3) is provided with a press type rebounder (32).

7. The portable temperature control device for detecting viral nucleic acid by RPA technology according to claim 4, wherein said sample bottle placing cavity (3) is axially and rotatably provided with a cover (33), and the outer wall of said cover (33) facing to the side of the port of said sample bottle placing cavity (3) is provided with a heat-insulating sealing ring.

8. The portable temperature control device for detecting virus nucleic acid by RPA technology according to claim 4, wherein said thermal insulation panel (43) is provided with a temperature detector for detecting the temperature of the space where the thermal waistcoat column (431) and the thermal waistcoat skirt (44) are located and transmitting the collected data to the circuit board.

9. The portable temperature control device for detecting viral nucleic acid by RPA technology according to claim 1, wherein said case cover (7) has a storage battery inside, said storage battery is used to supply power to said circuit board and said refrigeration component (4), said case cover (7) has a USB interface and a power switch on its side, said USB interface is assembled to be directly connected to the commercial power to supplement the power to said storage battery, said power switch is used to control the circuit to open and close.

10. The portable temperature control device for detecting viral nucleic acid by RPA technology as claimed in claim 1, wherein the outer walls of two opposite sides of said box (1) are respectively connected with nylon braces.