CN214472808U - Objective lens mounting structure, optical system and sample analyzer - Google Patents

Objective lens mounting structure, optical system and sample analyzer Download PDF

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Publication number
CN214472808U
CN214472808U CN202023008977.8U CN202023008977U CN214472808U CN 214472808 U CN214472808 U CN 214472808U CN 202023008977 U CN202023008977 U CN 202023008977U CN 214472808 U CN214472808 U CN 214472808U
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objective lens
reference surface
sample
lens mounting
mounting reference
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CN202023008977.8U
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徐家宏
林冲
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Shenzhen Reetoo Biotechnology Co Ltd
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Shenzhen Reetoo Biotechnology Co Ltd
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Abstract

The application relates to an objective lens mounting structure, an optical system and a sample analyzer, wherein an objective lens bearing assembly for mounting an objective lens is provided with different mounting reference surfaces, and the distance from a first mounting reference surface to a sample to be measured is larger. The first objective lens mounting reference surface is used for mounting a first objective lens with larger magnification, the second objective lens mounting reference surface is used for mounting a second objective lens with smaller magnification, and the first objective lens and the second objective lens are mounted in a parallel manner. Through the scheme, when the sample to be detected is scanned by adopting the lower-power objective lens, because the distance between the mounting position of the higher-power objective lens and the sample to be detected is larger, the collision between the higher-power objective lens and the sample to be detected or a sample bearing part can be effectively avoided, the conditions that the objective lens is damaged, the sample to be detected is damaged or a slide is broken and the like are avoided, and the working reliability is higher.

Description

Objective lens mounting structure, optical system and sample analyzer
Technical Field
The present application relates to the field of optical technologies, and in particular, to an objective lens mounting structure, an optical system, and a sample analyzer.
Background
An Optical Microscope (OM) is an Optical instrument that uses the Optical principle to magnify and image a minute object that cannot be resolved by human eyes, so as to extract information on a minute structure. The objective lens is the most important component for determining the performance of the microscope, and is called an objective lens or an objective lens because the objective lens needs to be close to an observed object when in use; the magnification of the objective lens is proportional to its length, the larger the magnification of the objective lens, the longer the objective lens. In the use process of the optical microscope, the objective lenses with different magnifications are often needed to be adopted to observe the object at the same time, which requires that the same optical microscope is simultaneously provided with the high-power objective lens with larger magnification and the low-power objective lens with smaller magnification.
Traditional high low power objective mounting structure has carousel formula and block, and the carousel formula adopts steel ball and shrinkage pool cooperation location, rotates the objective of corresponding multiple to the top of observing the object through rotating the carousel when needs use, but the carousel formula can not satisfy the high application of central location requirement at high low power objective, and takes place wearing and tearing easily and influence positioning accuracy. Although the high-low power objective lenses are designed according to a uniform parfocal distance (i.e. the distance from the mounting end surface of the objective lens to the surface of the sample), due to the length difference between the high-low power objective lenses, the high-low power objective lenses are easily interfered with the sample or a sample bearing member during low-power scanning, and the conditions of damage of the objective lenses, damage of the sample or breakage of the slide glass occur. Therefore, the conventional objective lens mounting structure has a disadvantage of poor operational reliability.
SUMMERY OF THE UTILITY MODEL
In view of the above, it is necessary to provide an objective lens mounting structure, an optical system, and a sample analyzer, which are capable of solving the problem of poor operational reliability of the conventional objective lens mounting structure.
An objective lens mounting structure comprising: an objective lens bearing assembly having a first objective lens mounting datum surface and a second objective lens mounting datum surface; a first objective lens fixedly arranged on the first objective lens mounting reference surface; the magnification of the second objective lens is smaller than that of the first objective lens, the second objective lens and the first objective lens are arranged in parallel, and the second objective lens is fixedly arranged on a second objective lens mounting reference surface; the first objective lens mounting reference surface and the second objective lens mounting reference surface are parallel to each other, and the distance between the first objective lens mounting reference surface and a sample to be measured is larger than the distance between the second objective lens mounting reference surface and the sample to be measured.
In one embodiment, the objective lens mounting structure further comprises an actuator, the objective lens carrying assembly being connected to the actuator.
In one embodiment, the transmission mechanism comprises a motor, a coupling and a screw rod, the motor is connected with the coupling, the coupling is connected with the screw rod, and the screw rod is connected with the objective lens bearing assembly.
In one embodiment, the transmission mechanism further comprises a reduction gearbox, the motor is connected with the reduction gearbox, and the reduction gearbox is connected with the coupling.
In one embodiment, the actuator further includes a guide rail disposed in a direction perpendicular to the first objective lens mounting reference plane, the objective lens bearing assembly being disposed on the guide rail.
In one embodiment, the height of the first objective lens mounting reference surface from the sample to be measured is at least 0.5 mm greater than the height of the second objective lens mounting reference surface from the sample to be measured, or the height of the first objective lens mounting reference surface from the sample to be measured is 1 mm greater than the height of the second objective lens mounting reference surface from the sample to be measured.
In one embodiment, the number of the first objective lenses is two or more.
In one embodiment, the objective lens mounting structure further comprises a third objective lens, the objective lens bearing assembly further comprises a third objective lens mounting reference surface, the third objective lens mounting reference surface and the second objective lens mounting reference surface are parallel to each other, the height from the second objective lens mounting reference surface to the sample to be measured is greater than the height from the third objective lens mounting reference surface to the sample to be measured, the magnification of the third objective lens is less than that of the second objective lens, the third objective lens, the first objective lens and the second objective lens are arranged in parallel, and the third objective lens is fixedly arranged on the third objective lens mounting reference surface.
An optical system comprising the objective lens mounting structure described above.
A sample analyzer includes an optical system and a sample detection system, the optical system being coupled to the sample detection system.
Above-mentioned objective mounting structure, optical system and sample analysis appearance for the objective bearing component of objective installation is provided with different installation reference surfaces, and wherein, the distance of first installation reference surface apart from the sample that awaits measuring is great. The first objective lens mounting reference surface is used for mounting a first objective lens with larger magnification, the second objective lens mounting reference surface is used for mounting a second objective lens with smaller magnification, and the first objective lens and the second objective lens are mounted in a parallel manner. Through the scheme, when the sample to be detected is scanned by adopting the lower-power objective lens, because the distance between the mounting position of the higher-power objective lens and the sample to be detected is larger, the collision between the higher-power objective lens and the sample or a sample bearing part can be effectively avoided, the situations that the objective lens is damaged, the sample is damaged or a glass slide is broken and the like are avoided, and the working reliability is higher.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments or the conventional technologies of the present application, the drawings used in the descriptions of the embodiments or the conventional technologies will be briefly introduced below, it is obvious that the drawings in the following descriptions are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic view of an objective lens mounting structure according to an embodiment;
FIG. 2 is a schematic view of an objective lens mounting structure in another embodiment;
FIG. 3 is a schematic front view of an objective lens mounting structure according to an embodiment;
FIG. 4 is a schematic rear view of an objective lens mounting structure according to an embodiment;
fig. 5 is a perspective view of an objective lens mounting structure according to an embodiment.
Detailed Description
To facilitate an understanding of the present application, the present application will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present application are illustrated in the accompanying drawings. This application may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Referring to fig. 1, an objective lens mounting structure includes: an objective lens bearing assembly 10 having a first objective lens mounting reference surface 11 and a second objective lens mounting reference surface 12; a first objective lens 20 fixedly provided on the first objective lens mounting reference surface 11; the magnification of the second objective lens 30 is smaller than that of the first objective lens 20, the second objective lens 30 and the first objective lens 20 are arranged in parallel, the second objective lens 30 is fixedly arranged on a second objective lens mounting reference surface 12, the first objective lens mounting reference surface 11 and the second objective lens mounting reference surface 12 are parallel to each other, and the height of the first objective lens mounting reference surface 11 from a sample to be measured is larger than the height of the second objective lens mounting reference surface 12 from the sample to be measured.
Specifically, the objective lens bearing assembly 10 is an assembly for mounting an objective lens, and the objective lens bearing assembly 10 of the present embodiment has two different objective lens mounting reference surfaces, namely a first objective lens mounting reference surface 11 and a second objective lens mounting reference surface 12. In the actual objective lens design, the same parfocal design (generally 45 mm or 60 mm) needs to be performed on the first objective lens 20 and the second objective lens 30, that is, the distance from the first objective lens mounting reference surface 11 corresponding to the first objective lens 20 to the surface of the sample to be measured is the same as the distance from the second objective lens mounting reference surface 12 corresponding to the second objective lens 30 to the surface of the sample to be measured. However, for the first objective lens 20 with a large magnification, the corresponding length is also higher than that of the second objective lens 30 with a small magnification, and when the second objective lens 30 is used for observation, the distance from the first objective lens 20 to the sample to be measured is far smaller than that from the second objective lens 30 to the sample to be measured, and if the second objective lens 30 is used for scanning, the first objective lens 20 is easily contacted with the sample to be measured or the slide, so that the situations of damage of the objective lens, damage of the sample to be measured, fracture of the slide, and the like occur.
The distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured, that is, the distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured. In this embodiment, the mounting reference surfaces of the first objective lens 20 and the second objective lens 30 are respectively arranged, facing and perpendicular to the direction of the first objective lens mounting reference surface 11, and the first mounting reference surface of the first objective lens 20 is higher than the second mounting reference surface of the second objective lens 30, so that when the second objective lens 30 is used, the distance from the first objective lens 20 to the sample to be measured is increased, and further, when the low-power scanning is performed, the possibility that the first objective lens 20 contacts with the sample to be measured or the slide is reduced, and further, the situations that the objective lens is damaged, the sample to be measured is damaged, or the slide is broken are avoided.
It should be noted that the direction facing and perpendicular to the first objective lens mounting reference surface 11 is not exclusive, and differs depending on the direction in which the first objective lens 20 and the second objective lens 30 observe the sample to be measured. For example, in one embodiment, if the first objective lens 20 and the second objective lens 30 both perform the observation of the sample to be measured through the direction perpendicular to the horizontal plane, the corresponding first objective lens mounting reference surface 11 and the corresponding second objective lens mounting reference surface are parallel to the horizontal plane, and the direction facing and perpendicular to the first objective lens mounting reference surface 11 is the direction perpendicular to the horizontal plane. It can be understood that, in other embodiments, if the direction in which the sample to be detected needs to be observed is not perpendicular to the horizontal plane, the direction facing and perpendicular to the first objective lens installation reference surface 11 may also be a direction forming other included angles with the horizontal plane, or even a direction parallel to the horizontal plane, as long as it can be ensured that the distance from the first objective lens installation reference surface 11 to the sample to be detected is greater than the distance from the second objective lens installation reference surface to the sample to be detected, so that the high power objective lens has a suitable distance from the surface of the sample to be detected during the scanning of the low power objective lens, and the contact can be avoided.
Referring to fig. 2, in one embodiment, the objective lens mounting structure further includes an actuator 40, and the objective lens bearing assembly 10 is connected to the actuator 40.
Specifically, in the present embodiment, since the first objective lens 20 with a larger magnification is installed higher in the direction facing and perpendicular to the first objective lens installation reference surface 11, so that the first objective lens installation reference surface 11 is inconsistent with the second objective lens installation reference surface 12, in order to ensure the accuracy of the detection of the sample to be detected, the first objective lens 20 and the second objective lens 30 need to be controlled to observe on the reference surface at the same distance from the sample to be detected. Therefore, in the present embodiment, the objective lens mounting structure further includes a transmission mechanism 40, the transmission mechanism 40 is connected to the objective lens bearing assembly 10, and when the first objective lens 20 is used for observation, the objective lens bearing assembly 10 can be moved by a certain distance through the transmission mechanism 40, so that the height of the first objective lens mounting reference surface 11 reaches the height of the second objective lens mounting reference surface 12 when the second objective lens 30 is used, thereby achieving the effect of observing the sample wafer on the same reference surface by the first objective lens 20 and the second objective lens 30 respectively.
In order to facilitate understanding of the embodiments of the present application, the following explanation is made with reference to the direction facing and perpendicular to the first objective lens mounting reference surface 11 as the direction perpendicular to the horizontal plane, and accordingly, when the height of the first objective lens mounting reference surface 11 from the horizontal plane is greater than the height of the second objective lens mounting reference surface from the horizontal plane, the first objective lens mounting reference surface 11 needs to be controlled to descend by the actuator 40 when performing observation by using the first objective lens 20.
It is understood that, in one embodiment, in order to avoid taking too much time for the first objective mounting reference surface 11 to descend and affecting the scanning efficiency of the optical system using this structure, in one embodiment, the time required for the first objective mounting reference surface 11 to descend to the same height as the second objective mounting reference surface 12 when the second objective 30 is used for observation can be reduced by increasing the transmission rate of the transmission mechanism 40, and in particular, the time can be realized by using a motor with strong driving capability, and the like.
It should be noted that the specific form of the transmission mechanism 40 is not exclusive, and referring to fig. 3-5, in one embodiment, the transmission mechanism 40 includes a motor 41, a coupling 43, and a lead screw 44, the motor 41 is connected to the coupling 43, the coupling 43 is connected to the lead screw 44, and the lead screw 44 is connected to the objective lens carrier assembly 10.
Specifically, the coupling 43 is a transitional coupling commonly used in mechanical transmissions to absorb vibration and compensate for radial and angular misalignment. The lead screw 44, i.e. a ball screw, is a device for converting a rotary motion into a linear motion, or converting a linear motion into a rotary motion, and in this embodiment, the lead screw 44 is used to convert a rotary motion into a linear motion, so that the objective lens bearing assembly 10 connected thereto moves in a vertical direction, and since it has a small frictional resistance, it is possible to realize precise motion control of the objective lens bearing assembly 10. In the embodiment, the motor 41 is driven to control the movement of the objective lens bearing assembly 10, and when a user needs to observe a sample by using the first objective lens 20, the motor 41 is turned on. The motor 41 transmits power to the screw rod 44 through the coupling 43 to drive the screw rod 44 to rotate, the screw rod 44 further drives the objective lens bearing assembly 10 to move downwards along the vertical direction, and finally the first objective lens mounting reference surface 11 is lowered to the same position height as the original first objective lens mounting reference surface 11, so that the user uses the first objective lens 20 to realize sample observation.
Further, referring to fig. 3-5, in an embodiment, the transmission mechanism 40 further includes a reduction box 42, the motor 41 is connected to the reduction box 42, and the reduction box 42 is connected to the coupling 43.
Specifically, the reduction gearbox 42, i.e., reducer, is an independent component consisting of a gear drive, a worm drive, and a gear-worm drive enclosed within a rigid housing, and functions to match rotational speed and transmit torque between the prime mover and the work machine or actuator. In the embodiment, the reduction gearbox 42 is further arranged between the motor 41 and the coupling 43, the output torque can be increased while the speed is reduced through the reduction gearbox 42, the inertia of the load is reduced while the speed is reduced, and the driving reliability of the transmission mechanism 40 is effectively improved.
Further, referring to fig. 3-5, in one embodiment, the driving mechanism 40 further includes a guide rail 45, the guide rail 45 is along a direction perpendicular to the first objective mounting reference plane 11, and the objective lens supporting assembly 10 is disposed on the guide rail 45.
Specifically, the direction perpendicular to the first objective lens mounting reference surface 11 may be a direction perpendicular to a horizontal plane. Guide rail 45 is a groove or ridge made of metal or other material that can receive, hold, guide and reduce friction of a moving device or apparatus. Longitudinal grooves or ridges on the surface of the guide rails 45 are used to guide, secure, machine parts, special equipment, instruments, etc., and this embodiment is used to guide the objective lens carrier assembly 10. The guide rail is also called as a slide rail, a linear guide rail and a linear slide rail, is used in the linear reciprocating motion occasion, has higher rated load than a linear bearing, can bear certain torque, and can realize high-precision linear motion under the condition of high load.
It should be noted that, in one embodiment, there are two guide rails 45, and the two guide rails 45 are oppositely arranged in a direction perpendicular to the horizontal plane, and the objective lens mounting assembly is arranged on the guide rails 45, and can move up and down along the guide rails 45 under the action of the screw 44, thereby realizing the height position adjustment of the first objective lens mounting reference surface 11.
In one embodiment, the number of the first objective lenses 20 is two or more.
Specifically, in this embodiment, the same objective lens mounting structure is provided with a plurality of first objective lenses 20, and the magnification factor of each first objective lens 20 is greater than that of the second objective lens 30, that is, the same objective lens mounting structure is provided with a plurality of objective lenses with a larger magnification factor, so as to meet the requirement that a user needs to use a plurality of high-power objective lenses. It should be noted that the magnifications of the first objective lenses 20 may be different from each other, and as long as the magnifications are larger than that of the second objective lens 30, the magnifications may be set on the same first objective lens mounting reference surface 11, and it is ensured that the second objective lens 30 does not contact with the sample or the slide to be measured during scanning.
Further, in an embodiment, the objective lens mounting structure further includes a third objective lens, the objective lens bearing assembly 10 further has a third objective lens mounting reference surface, the third objective lens mounting reference surface and the second objective lens mounting reference surface 12 are parallel to each other, a height of the second objective lens mounting reference surface 12 from the sample to be measured is greater than a height of the third objective lens mounting reference surface from the sample to be measured, an amplification factor of the third objective lens is smaller than that of the second objective lens, the third objective lens, the first objective lens 20 and the second objective lens 30 are arranged in parallel, and the third objective lens is fixedly arranged on the third objective lens mounting reference surface.
Specifically, in this embodiment, the objective bearing assembly 10 can simultaneously mount three objectives with different high magnifications, and the height of the correspondingly high mounting reference surface of the objective with a low magnification is also low, so that when the use requirement of the user on multiple objectives is met, the objective with a low magnification can be prevented from being scanned, the objective with a high magnification cannot be contacted with a sample to be detected or a slide.
It should be noted that, in other embodiments, four or more objective lens mounting reference surfaces may be disposed on the objective lens bearing assembly 10, as long as the height of the objective lens mounting reference surface corresponding to the objective lens with smaller magnification from the horizontal plane is also correspondingly smaller (or the distance of the objective lens mounting reference surface corresponding to the objective lens with smaller magnification from the sample to be tested is also correspondingly smaller), so as to ensure that the objective lens with higher magnification does not contact with the sample to be tested or the slide when the objective lens with lower magnification is used for scanning.
In one embodiment, the height of the first objective mounting reference surface 11 from the sample to be measured is at least 0.5 mm greater than the height of the second objective mounting reference surface 12 from the sample to be measured.
Specifically, a direction facing and perpendicular to the first objective lens mounting reference surface 11 is taken as a perpendicular-to-horizontal plane direction as an example. In an actual optical system, the flatness of the slide and the height distance of the sample to be measured are both very small, and the maximum distance is not more than 0.5 mm, so that when the first objective lens mounting reference surface 11 and the second objective lens mounting reference surface 12 are actually designed, the height of the first objective lens mounting reference surface 11 is only required to be designed to be higher than the height of the first objective lens mounting reference surface 11 by more than 0.5 mm, and the first objective lens 20 can be ensured not to contact with the sample wafer or the slide during low power lens scanning. Therefore, in the present embodiment, the height of the first objective lens mounting reference surface 11 from the horizontal plane can be designed to be at least 0.5 mm greater than the height of the second objective lens mounting reference surface 12 from the horizontal plane.
Further, in one embodiment, the difference in height between the first objective mounting reference surface 11 and the second objective mounting reference surface 12 cannot be infinite, and in one embodiment, may be greater than 0.5 mm and less than 10 mm, subject to limitations such as the length of the objective lens, the parfocal distance, and the size of the objective lens bearing assembly 10. It is understood that, in other embodiments, the distance may be greater than 10 mm, etc., as long as the distance is greater than 0.5 mm and meets the design requirements of the optical system to which the objective lens mounting structure is applied.
In one embodiment, the height of the first objective mounting reference surface 11 from the sample to be measured is greater than the height of the second objective mounting reference surface 12 from the sample to be measured by 1 mm.
Specifically, a direction facing and perpendicular to the first objective lens mounting reference surface 11 is taken as a perpendicular-to-horizontal plane direction as an example. In this embodiment, the height of the first objective lens mounting reference surface 11 from the horizontal plane is designed to be greater than the height of the second objective lens mounting reference surface 12 from the horizontal plane by 1 mm, that is, in the objective lens mounting assembly, the first objective lens mounting reference surface 11 is disposed 1 mm above the second objective lens mounting reference surface 12, and this distance can not only meet the requirement of the above embodiment that the distance is greater than 0.5 mm, but also avoid the scanning efficiency being affected by too large distance.
It should be noted that the specific structure of the objective lens bearing assembly 10 is not exclusive, and in one embodiment, the objective lens bearing structure is a moving plate which is connected to the transmission mechanism 40, specifically arranged on the guide rail 45 of the transmission mechanism 40, and connected with the screw 44, and can move up and down along the guide rail 45 under the driving of the motor 41 of the transmission mechanism 40.
In the objective lens mounting structure, the objective lens bearing component 10 for mounting the objective lens is provided with different mounting reference surfaces, wherein the distance from the first mounting reference surface to the sample to be measured is larger. The first objective lens mounting reference surface 11 is used for mounting the first objective lens 20 with larger magnification, the second objective lens mounting reference surface 12 is used for mounting the second objective lens 30 with smaller magnification, and the first objective lens 20 and the second objective lens 30 are mounted in parallel. Through the scheme, when the sample to be tested is scanned by adopting the lower-power objective lens, the distance between the mounting position of the higher-power objective lens and the sample to be tested is larger, so that the collision between the higher-power objective lens and the sample to be tested or a sample bearing part can be effectively avoided, the conditions that the objective lens is damaged, the sample to be tested is damaged or a glass slide is broken and the like are avoided, and the working reliability is higher.
An optical system comprises the objective lens mounting structure.
Specifically, as shown in the above embodiments and the accompanying drawings, the objective lens mounting structure can be applied to an optical system (e.g. an optical microscope) to ensure that a high power objective lens does not contact with a sample or a slide to be measured when the optical system performs scanning of a low power objective lens, thereby effectively ensuring the use reliability of the optical system. The objective lens mounting structure specifically comprises an objective lens bearing assembly 10 having a first objective lens mounting reference surface 11 and a second objective lens mounting reference surface 12; a first objective lens 20 fixedly provided on the first objective lens mounting reference surface 11; the magnification of the second objective lens 30 is smaller than that of the first objective lens 20, the second objective lens 30 and the first objective lens 20 are arranged in parallel, the second objective lens 30 is fixedly arranged on a second objective lens mounting reference surface 12, the first objective lens mounting reference surface 11 and the second objective lens mounting reference surface 12 are parallel to each other, and the height of the first objective lens mounting reference surface 11 from a sample to be measured is larger than the height of the second objective lens mounting reference surface 12 from the sample to be measured.
The objective lens bearing assembly 10 is an assembly for mounting an objective lens, and the objective lens bearing assembly 10 of the present embodiment has two different objective lens mounting reference surfaces, namely a first objective lens mounting reference surface 11 and a second objective lens mounting reference surface 12. In the actual objective lens design, the same parfocal design (generally 45 mm or 60 mm) needs to be performed on the first objective lens 20 and the second objective lens 30, that is, the distance from the first objective lens mounting reference surface 11 corresponding to the first objective lens 20 to the surface of the sample to be measured is the same as the distance from the second objective lens mounting reference surface 12 corresponding to the second objective lens 30 to the surface of the sample to be measured. However, for the first objective lens 20 with a large magnification, the corresponding length is also higher than that of the second objective lens 30 with a small magnification, and when the second objective lens 30 is used for observation, the distance from the first objective lens 20 to the sample to be measured is far smaller than that from the second objective lens 30 to the sample to be measured, and if the second objective lens 30 is used for scanning, the first objective lens 20 is easily contacted with the sample to be measured or the slide, so that the situations of damage of the objective lens, damage of the sample to be measured, fracture of the slide, and the like occur.
The distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured, that is, the distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured. In this embodiment, the mounting reference surfaces of the first objective lens 20 and the second objective lens 30 are respectively arranged, facing and perpendicular to the direction of the first objective lens mounting reference surface 11, and the first mounting reference surface of the first objective lens 20 is higher than the second mounting reference surface of the second objective lens 30, so that when the second objective lens 30 is used, the distance from the first objective lens 20 to the sample to be measured is increased, and further, when the low-power scanning is performed, the possibility that the first objective lens 20 contacts with the sample to be measured or the slide is reduced, and further, the situations that the objective lens is damaged, the sample to be measured is damaged, or the slide is broken are avoided.
In the optical system, the objective lens bearing assembly 10 for mounting the objective lens is provided with different mounting reference surfaces, wherein the distance from the first mounting reference surface to the sample to be measured is larger. The first objective lens mounting reference surface 11 is used for mounting the first objective lens 20 with larger magnification, the second objective lens mounting reference surface 12 is used for mounting the second objective lens 30 with smaller magnification, and the first objective lens 20 and the second objective lens 30 are mounted in parallel. Through the scheme, when the sample to be tested is scanned by adopting the lower-power objective lens, the distance between the mounting position of the higher-power objective lens and the sample to be tested is larger, so that the collision between the higher-power objective lens and the sample to be tested or a sample bearing part can be effectively avoided, the conditions that the objective lens is damaged, the sample to be tested is damaged or a glass slide is broken and the like are avoided, and the working reliability is higher.
A sample analyzer comprises an optical system and a sample detection system, wherein the optical system is connected with the sample detection system. The sample detecting system can be used to detect and analyze information such as components of a sample to be detected, the optical system can be used to magnify and observe the sample to be detected, the objective lens mounting structure in the optical system is specifically as described in the above embodiments and shown in the drawings, the objective lens bearing assembly 10 has two different objective lens mounting reference surfaces, namely, a first objective lens mounting reference surface 11 and a second objective lens mounting reference surface 12. In the actual objective lens design, the same parfocal design (generally 45 mm or 60 mm) needs to be performed on the first objective lens 20 and the second objective lens 30, that is, the distance from the first objective lens mounting reference surface 11 corresponding to the first objective lens 20 to the surface of the sample to be measured is the same as the distance from the second objective lens mounting reference surface 12 corresponding to the second objective lens 30 to the surface of the sample to be measured. However, for the first objective lens 20 with a large magnification, the corresponding length is also higher than that of the second objective lens 30 with a small magnification, and when the second objective lens 30 is used for observation, the distance from the first objective lens 20 to the sample to be measured is far smaller than that from the second objective lens 30 to the sample to be measured, and if the second objective lens 30 is used for scanning, the first objective lens 20 is easily contacted with the sample to be measured or the slide, so that the situations of damage of the objective lens, damage of the sample to be measured, fracture of the slide, and the like occur.
The distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured, that is, the distance from the first objective lens installation reference surface 11 to the sample to be measured is greater than the distance from the second objective lens installation reference surface 12 to the sample to be measured. In this embodiment, the mounting reference surfaces of the first objective lens 20 and the second objective lens 30 are respectively arranged, facing and perpendicular to the direction of the first objective lens mounting reference surface 11, and the first mounting reference surface of the first objective lens 20 is higher than the second mounting reference surface of the second objective lens 30, so that when the second objective lens 30 is used, the distance from the first objective lens 20 to the sample to be measured is increased, and further, when the low-power scanning is performed, the possibility that the first objective lens 20 contacts with the sample to be measured or the slide is reduced, and further, the situations that the objective lens is damaged, the sample to be measured is damaged, or the slide is broken are avoided.
In the sample analyzer, the objective lens bearing assembly 10 for mounting the objective lens in the optical system is provided with different mounting reference surfaces, wherein the first mounting reference surface has a larger distance from the sample to be measured. The first objective lens mounting reference surface 11 is used for mounting the first objective lens 20 with larger magnification, the second objective lens mounting reference surface 12 is used for mounting the second objective lens 30 with smaller magnification, and the first objective lens 20 and the second objective lens 30 are mounted in parallel. Through the scheme, when the sample to be tested is scanned by adopting the lower-power objective lens, the distance between the mounting position of the higher-power objective lens and the sample to be tested is larger, so that the collision between the higher-power objective lens and the sample to be tested or a sample bearing part can be effectively avoided, the conditions that the objective lens is damaged, the sample to be tested is damaged or a glass slide is broken and the like are avoided, and the working reliability is higher.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. An objective lens mounting structure, comprising:
an objective lens bearing assembly having a first objective lens mounting datum surface and a second objective lens mounting datum surface;
a first objective lens fixedly arranged on the first objective lens mounting reference surface;
the magnification of the second objective lens is smaller than that of the first objective lens, the second objective lens and the first objective lens are arranged in parallel, and the second objective lens is fixedly arranged on a second objective lens mounting reference surface;
the first objective lens mounting reference surface and the second objective lens mounting reference surface are parallel to each other, and the distance between the first objective lens mounting reference surface and a sample to be measured is larger than the distance between the second objective lens mounting reference surface and the sample to be measured.
2. An objective lens mounting structure as claimed in claim 1, further comprising a transmission mechanism to which the objective lens carrying assembly is connected.
3. An objective lens mounting structure as claimed in claim 2, wherein the transmission mechanism includes a motor, a coupling, and a lead screw, the motor being connected to the coupling, the coupling being connected to the lead screw, the lead screw being connected to the objective lens bearing assembly.
4. An objective lens mounting structure as claimed in claim 3, wherein the transmission mechanism further comprises a reduction gearbox, the motor is connected with the reduction gearbox, and the reduction gearbox is connected with the coupling.
5. An objective lens mounting structure according to claim 3, wherein the actuator further includes a guide rail provided in a direction perpendicular to the first objective lens mounting reference surface, the objective lens bearing assembly being provided to the guide rail.
6. An objective lens mounting structure as claimed in any one of claims 1 to 5, wherein the first objective lens mounting reference surface is at least 0.5 mm higher than the second objective lens mounting reference surface from the sample to be measured, or
The height from the first objective lens installation reference surface to the sample to be measured is larger than the height from the second objective lens installation reference surface to the sample to be measured by 1 mm.
7. The objective lens mounting structure according to claim 1, wherein the number of the first objective lenses is two or more.
8. An objective lens mounting structure according to claim 1, further comprising a third objective lens, wherein the objective lens bearing assembly further has a third objective lens mounting reference surface, the third objective lens mounting reference surface and the second objective lens mounting reference surface are parallel to each other, a height of the second objective lens mounting reference surface from a sample to be measured is larger than a height of the third objective lens mounting reference surface from the sample to be measured, an amplification factor of the third objective lens is smaller than an amplification factor of the second objective lens, the third objective lens, the first objective lens and the second objective lens are arranged in parallel, and the third objective lens is fixedly arranged on the third objective lens mounting reference surface.
9. An optical system comprising the objective lens mounting structure of any one of claims 1 to 8.
10. A sample analyzer comprising the optical system of claim 9 and a sample detection system, the optical system being coupled to the sample detection system.
CN202023008977.8U 2020-12-15 2020-12-15 Objective lens mounting structure, optical system and sample analyzer Active CN214472808U (en)

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CN202023008977.8U CN214472808U (en) 2020-12-15 2020-12-15 Objective lens mounting structure, optical system and sample analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
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CN214472808U true CN214472808U (en) 2021-10-22

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