CN213994358U

CN213994358U - Companion formula sterilization apparatus

Info

Publication number: CN213994358U
Application number: CN202022890258.7U
Authority: CN
Inventors: 陈皓; 蒋雷
Original assignee: Innovel Intelligent Technology Suzhou Co Ltd
Current assignee: Innovel Intelligent Technology Suzhou Co Ltd
Priority date: 2020-12-03
Filing date: 2020-12-03
Publication date: 2021-08-20
Anticipated expiration: 2030-12-03

Abstract

The utility model relates to the technical field of biological medicine preparation, in particular to a concomitant sterilization device, which comprises a protective gasket, a protective cover and a movable base, wherein a culture container is arranged at the middle part of the upper end of the movable base, the protective cover is arranged at the part of the upper end of the movable base, which is close to the outer part of the culture container, the protective gasket is arranged at the part of the upper end of the inner part of the protective cover, the protective cover is jointed and sealed with the movable base, the culture container is placed inside, the sterilization is convenient, the internal sealing of the sterilization device is realized, the sterilization process sterilization link is ensured, sterilization media are prevented from entering the cell culture container, the movement, the installation and the replacement are convenient, the sterilized protective cover and the sealing and protecting pad are connected into a whole, the disassembly and the replacement between the movable base are convenient, the installation is simple, the installation is reliable, the modularized design is suitable for batch production, the automatic mass cell culture is suitable, the sterilization and the residual discharge time in the traditional production mode is greatly reduced, the efficiency of parallel production in the automated production process is improved, and the whole effect is good.

Description

Companion formula sterilization apparatus

Technical Field

The utility model relates to a biological medicine preparation technical field specifically is an adjoint sterilization apparatus.

Background

The preparation of biological medicines is in a rapid development stage at present, and novel cellular immune medicines such as CAR-T, TCR-T and the like are about to be put into large-scale use. In the process of cell culture, a sterilization link exists, and meanwhile, in the process of cell culture, air needs to be exchanged between the inside and the outside of the cell culture container, so that a sterilization medium enters the cell culture container along with air exchange, and cell culture is influenced. Currently, there is no technical solution available on the market for preventing the sterilization medium from entering into the cell culture vessel during the automated, large-scale cell culture process, and therefore a concomitant sterilization device is needed to improve the above problems.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an adjoint sterilization apparatus to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme:

the utility model provides an attendant formula sterilization apparatus, includes protective gasket, protective cover and removes the base, it is equipped with the culture container to remove the department in the middle of the base upper end, it is equipped with the protective cover to remove the base upper end near the outside department of culture container, the inside upper end of protective cover is equipped with protective gasket near culture container department.

Preferably, the protective gasket and the protective cover are bonded together.

Preferably, the protective cover is attached to and sealed with the movable base.

Preferably, the protective gasket is of an integrally formed structure.

Preferably, the protective cover is of an integrally formed structure.

Preferably, the culture container is connected with the protective cover and the movable base in a sleeved mode.

Preferably, the mobile base is connected with the robot in a clamping mode.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses in, through the protection gasket that sets up, the sealed portion of culture vessel mouth adopts integrated into one piece's protection gasket to seal, and the protection gasket has good profile modeling adaptability, can guarantee to seal.

2. The utility model discloses in, through the protective cover that sets up, the sealed part of culture vessel body adopts integrated into one piece's protective cover to seal, can effectually cut off sterilization medium and get into culture vessel, can guarantee to seal, and the installation is changed conveniently.

3. The utility model discloses in, through the removal base that sets up, the protective cover is sealed with the removal base laminating, and the inside is placed to the culture container, and it is convenient to disinfect, realizes sterilizing equipment's inside seal, and the guarantee prevents that the sterilization medium from getting into the cell culture container in the production process sterilization link, removes and installs the change convenience, removes the centre gripping between base and the robot and connects, is fit for automatic operation, the full automatic operation of the robot of being convenient for, and the resource consumption is reduced, improve equipment inner space, resource utilization.

4. The utility model discloses the protective cover and the sealed protection pad of well sterilization are linked into an organic whole, and remove between the base and tear open and trade the convenience to can guarantee that the simple installation is reliable, the modular design is applicable to batch production, is fit for automatic big batch cell culture, and the traditional mode of production that significantly reduces is sterilized and is arranged incomplete time, improves the efficiency of parallel production in the automated production process greatly.

Drawings

FIG. 1 is an overall structure diagram of the present invention;

fig. 2 is an internal structure diagram of the present invention.

In the figure: 1. a protective pad; 2. a protective cover; 3. moving the base; 4. a culture vessel.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative work belong to the protection scope of the present invention based on the embodiments of the present invention.

In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. Several embodiments of the invention are given in the accompanying drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1-2, the present invention provides a technical solution:

the utility model provides an adjoint sterilization apparatus, including protective gasket 1, protective cover 2 and removal base 3, it is equipped with culture container 4 to remove 3 upper ends middle departments of base, it is equipped with protective cover 2 to remove 3 upper ends of base near culture container 4 outside departments, culture container 4 and protective cover 2, it connects to remove to cup joint between the base 3, protective cover 2 is the integrated into one piece structure, protective cover 2 is sealed with removing 3 laminating of base, the inside upper end of protective cover 2 is close to culture container 4 departments and is equipped with protective gasket 1, protective gasket 1 is the integrated into one piece structure, bonding connection between protective gasket 1 and the protective cover 2.

The utility model discloses work flow: firstly, through the arranged protective gasket 1, the sealing part of the mouth of the culture container 4 is sealed by the integrally formed protective gasket 1, the protective gasket 1 has good profiling adaptability and can ensure sealing, through the arranged protective cover 2, the sealing part of the bottle body of the culture container 4 is sealed by the integrally formed protective cover 2, the sterilization medium can be effectively prevented from entering the culture container 4, the sealing can be ensured, the installation and the replacement are convenient, through the arranged movable base 3, the protective cover 2 is in fit sealing with the movable base 3, the culture container 4 is placed inside, the sterilization is convenient, the internal sealing of the sterilization device is realized, the sterilization process sterilization link in the production process is ensured, the sterilization medium is prevented from entering the cell culture container, the moving, the installation and the replacement are convenient, the movable base 3 is in clamping connection with a robot, the automatic operation is suitable, and the full-automatic operation of the robot is convenient, the utility model has the advantages of reduce and consume the resource, improve equipment inner space, resource utilization, the protective cover 2 and the sealed protection pad 1 of sterilization are linked into an organic whole, and remove between the base 3 and tear open and trade the convenience, and can guarantee that the simple installation is reliable, the modularized design is applicable to batch production, be fit for automatic big batch cell culture, sterilization and row's incomplete time in the traditional production mode that significantly reduces, improve the efficiency of parallel production in the automated production process greatly, overall structure is simple, effectual, and stability and practicality are higher.

Examples

When carrying out an application, the robot is put into the culture container 4 that has disinfected and sterilized and is removed base 3, snatch protective cover 2 again, put into on removing base 3 protective cover 2, culture container 4 is kept apart inside sterilization apparatus this moment, the sterilization medium can't get into inside the blake bottle through the filter paper above culture container 4, the robot snatchs and removes base 3, remove whole device to required position environment, the outside sprays vaporific hydrogen peroxide and carries out the sterilization, then the robot snatchs and removes base 3, remove whole device to required position environment, the robot takes off protective cover 2, snatch culture container 4 to required position, accomplish the disinfection of whole culture container 4 transfer process, prevent effectively that the sterilization medium from getting into culture container 4 and influencing cell growth.

And whole device can adopt arbitrary mobile mode, not only is limited to the robot and snatchs the removal, and the protective cover 2 outward appearance of sterilization can optimize according to the demand and design into arbitrary form, arbitrary colour and transparency, and protective pad 1 can optimize according to the demand and become to select arbitrary suitable material and arbitrary suitable shape, removes base 3 and protective cover 2 and can cultivate container demand optimal design into arbitrary shape according to the difference, and container 4, the cultivation bag consumptive material are cultivateed to applicable different outward appearances.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides an companion's sterilization apparatus, includes protective gasket (1), protective cover (2) and removes base (3), its characterized in that: remove base (3) upper end middle department and be equipped with culture container (4), it is close to culture container (4) outside department and is equipped with protective cover (2) to remove base (3) upper end, the inside upper end of protective cover (2) is close to culture container (4) department and is equipped with protective gasket (1).

2. The concomitant sterilization apparatus according to claim 1, wherein: the protective gasket (1) and the protective cover (2) are connected in an adhesive mode.

3. The concomitant sterilization apparatus according to claim 1, wherein: the protective cover (2) is attached to the movable base (3) in a sealing mode.

4. The concomitant sterilization apparatus according to claim 1, wherein: the protective gasket (1) is of an integrally formed structure.

5. The concomitant sterilization apparatus according to claim 1, wherein: the protective cover (2) is of an integrally formed structure.

6. The concomitant sterilization apparatus according to claim 1, wherein: the culture container (4) is connected with the protective cover (2) and the movable base (3) in a sleeved mode.

7. The concomitant sterilization apparatus according to claim 1, wherein: the movable base (3) is connected with the robot in a clamping mode.