CN213829130U - A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece - Google Patents
A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece Download PDFInfo
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- CN213829130U CN213829130U CN202022810791.8U CN202022810791U CN213829130U CN 213829130 U CN213829130 U CN 213829130U CN 202022810791 U CN202022810791 U CN 202022810791U CN 213829130 U CN213829130 U CN 213829130U
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Abstract
The utility model provides a cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece, the device is fixed the umbilical cord on the objective table through the recess in the bearing structure, adopts the resilience cutting structure who takes latticed blade as the main to cut the umbilical cord, once presses down and can accomplish the cutting, can obtain the high quality umbilical cord tissue of even size, shear plane rule rapidly in the short time, and in view of the cutting time shortens greatly, has avoided the serious loss of umbilical cord tissue liquid, has effectively improved the survival rate of cell, has further guaranteed the later stage stem cell acquisition volume; meanwhile, the ejecting structure is further arranged in the device, and in the rebounding process after the grid-shaped blade is cut, the protrusions of the ejecting structure can eject the umbilical cord tissues in the grid gaps of the corresponding grid-shaped blade, so that the cut umbilical cord tissues are prevented from being jammed in the grid gaps and cannot be taken out, the waste of the umbilical cord tissues is reduced, and the cut samples are fully utilized.
Description
Technical Field
The utility model relates to a biological sample draws technical field, especially relates to a cutting device that is arranged in umbilical cord mesenchymal stem cell culture in-process umbilical cord tissue piece.
Background
The tissue adherence method for obtaining Mesenchymal Stem Cells (MSC) from umbilical cord tissue is a conventional technology, and the operation flow of the technology is as follows: the umbilical cord tissue is cut into a plurality of segments of 3-5cm, arteries and veins in the umbilical cord are torn off, and the umbilical cord tissue is manually cut into pieces and attached to the wall.
In the method, the umbilical cord tissue is only sheared by using common surgical scissors, and in the shearing process, the umbilical cord is tougher compared with other tissues, is not easy to fix and slides easily, so that the shearing surface is irregular, and the sheared umbilical cord tissue is not uniform in size; and the operation is labor-consuming and long in time, so that the umbilical cord tissue fluid loss is serious in the shearing process, cells are easy to inactivate, and the later-stage stem cell obtaining amount is seriously influenced.
SUMMERY OF THE UTILITY MODEL
In view of the above shortcoming of the prior art, the utility model aims at providing a simple operation, cutting efficiency height and can obtain the cutting device of umbilical cord tissue piece in the umbilical cord mesenchymal stem cell culture process of high quality umbilical cord tissue.
The utility model discloses by following technical scheme implement: a cutting device for umbilical cord tissue pieces during umbilical cord mesenchymal stem cell culture, the device comprising:
an object stage;
the supporting structure is arranged above the objective table and comprises two side plates and a top plate, the two side plates and the top plate are integrated to form a n-shaped bending plate, the bottoms of the two side plates are provided with grooves, and the top plate is provided with a round hole; and
the cutting structure comprises a pressure plate, a straight rod, a spring and a latticed blade, wherein the straight rod is inserted into the round hole of the top plate, the pressure plate is arranged at the top end of the straight rod, the spring is sleeved on the outer side of the straight rod between the pressure plate and the top plate, and the latticed blade is fixed at the bottom end of the straight rod.
Further, the height dimension of the groove at the bottom of the side plate of the supporting structure is smaller than the height of the umbilical cord.
Further, the distance between the grooves at the bottoms of the two side plates of the supporting structure is smaller than the length of the umbilical cord.
Furthermore, vertical bar-shaped through holes are formed in the two side plates of the supporting structure, T-shaped sliding blocks corresponding to the bar-shaped through holes are connected to the two ends of the latticed blade, and the T-shaped sliding blocks penetrate through the bar-shaped through holes.
Furthermore, the supporting structure is detachably connected with the object stage.
Further, the length and the width of the grid gap formed by the grid-shaped blade are both 1 mm.
Further, the mesh blade comprises a 304 stainless steel blade.
Further, the device further comprises an ejection structure, the ejection structure comprises a flat plate and a plurality of protrusions, the flat plate is fixed in the supporting structure and located above the latticed blades, the flat plate is provided with round holes so that the straight rod can penetrate through the round holes, and the protrusions are arranged on the lower surface of the flat plate and correspond to the latticed blades in a one-to-one mode.
Furthermore, the flat plate is fixedly connected with a top plate of the supporting structure through a hollow cylinder, and the straight rod is movably inserted in the hollow cylinder.
Further, the protrusions of the ejection structures include cylindrical protrusions and/or prismatic protrusions.
As mentioned above, the utility model has the advantages that:
the utility model provides a cutting device that is arranged in umbilical cord tissue piece among umbilical cord mesenchymal stem cell culture process, the device is fixed the umbilical cord on the objective table through the recess in the bearing structure, adopts the resilience cutting structure who takes latticed blade as the main to cut the umbilical cord, once presses down and can accomplish the cutting, can obtain the high quality umbilical cord tissue of even size, shear plane rule rapidly in the short time, and in view of the cutting time shortens greatly, has avoided the serious loss of umbilical cord tissue liquid, has effectively improved the survival rate of cell, has further guaranteed the later stage stem cell acquisition volume; meanwhile, the ejecting structure is further arranged in the device, and in the rebounding process after the grid-shaped blade is cut, the protrusions of the ejecting structure can eject the umbilical cord tissues in the grid gaps of the corresponding grid-shaped blade, so that the cut umbilical cord tissues are prevented from being jammed in the grid gaps and cannot be taken out, the waste of the umbilical cord tissues is reduced, and the cut samples are fully utilized.
Drawings
Fig. 1 is a schematic structural diagram of a cutting device for umbilical cord tissue mass during umbilical cord mesenchymal stem cell culture according to an embodiment of the present invention.
Fig. 2 is a simplified schematic illustration of a support structure top plate according to an embodiment of the present invention.
Fig. 3 is a simplified schematic illustration of a side panel of a support structure according to an embodiment of the present invention.
Fig. 4 shows a simplified plan view of a grid blade disclosed in an embodiment of the present invention.
Fig. 5 is a schematic diagram illustrating the grid voids of a grid blade corresponding to protrusions of an ejection structure in accordance with an embodiment of the present invention.
The reference numbers illustrate:
the object stage 1, the umbilical cord 2, the supporting structure 3, the side plate 31, the groove 311, the strip-shaped through hole 312, the top plate 32, the top plate circular hole 321, the cutting structure 4, the pressure plate 41, the straight rod 42, the spring 43, the grid-shaped blade 44, the grid gap 441, the T-shaped sliding block 5, the ejection structure 6, the flat plate 61, the flat plate circular hole 611, the hollow cylinder 612 and the protrusion 62.
Detailed Description
The following description of the embodiments of the present invention is provided for illustrative purposes, and other advantages and effects of the present invention will be apparent to those skilled in the art from the disclosure herein. The present application is capable of other and different embodiments and its several details are capable of modifications and/or changes in various respects, all without departing from the spirit of the present application. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict.
Please refer to fig. 1 to 5. It should be understood that the drawings provided in the embodiments of the present application are only for illustrating the basic concept of the present invention, and although only the components related to the present invention are shown in the drawings rather than being drawn according to the number, shape and size of the components in actual implementation, the form, quantity and proportion of the components in actual implementation may be changed at will, and the layout of the components may be more complicated. The structure, ratio, size and the like shown in the drawings are only used for matching with the content disclosed in the specification, so that those skilled in the art can understand and read the content, and do not limit the limit conditions that the present application can be implemented, so that the essence of the technology is not existed, and any structural modification, ratio relationship change or size adjustment should still fall within the scope that the technical content disclosed in the present application can cover without affecting the efficacy and the achievable purpose of the present invention.
The specific implementation mode is as follows:
the embodiment provides a cutting device for umbilical cord tissue blocks in an umbilical cord mesenchymal stem cell culture process, a schematic structural diagram of which is shown in fig. 1, the device comprising:
the object stage 1 is used for placing the umbilical cord 2;
the supporting structure 3 is arranged above the objective table 1, and comprises two side plates 31 and a top plate 32, the two side plates 31 and the top plate 32 form a n-shaped bending plate as a whole, the bottoms of the two side plates 31 are both provided with a groove 311 for fixing the umbilical cord 2, and the top plate 32 is provided with a round hole 321 as shown in fig. 2 and 3; and
the cutting structure 4, the cutting structure 4 includes a pressing plate 41, a straight rod 42, a spring 43 and a grid-shaped blade 44, wherein the straight rod 42 is inserted into the circular hole 321 of the top plate 32, the pressing plate 41 is disposed at the top end of the straight rod 42, the spring 43 is sleeved outside the straight rod 42 between the pressing plate 41 and the top plate 32, the grid-shaped blade 44 is fixed at the bottom end of the straight rod 42, and the structure of the grid-shaped blade 44 is as shown in fig. 4.
This device is fixed in on objective table 1 through recess 311 among the bearing structure 3 with navel cord 2, adopts and uses latticed blade 44 to cut the navel cord for 4 cutting structures that kick-backs of giving first place to, once presses and to accomplish the cutting, can obtain the high quality navel cord tissue that the size is even, the shear plane rule rapidly in the short time, and shorten greatly in view of cutting time, avoided the serious loss of navel cord tissue liquid, effectively improved the survival rate of cell, further guaranteed later stage stem cell acquisition volume.
As an example, the height dimension h of the recess 311 at the bottom of the side plate 31 of the support structure 3 is smaller than the height of the umbilical cord 2.
As an example, the distance a between the grooves 311 at the bottom of the two side plates 31 of the support structure 3 is smaller than the length of the umbilical cord 2.
It should be noted that, the size of each groove 311 and the distance between two grooves 311 need to be set according to the size of the umbilical cord 2, and when the height of the groove is smaller than the height of the umbilical cord 2 and the distance is smaller than the length of the umbilical cord 2, the two ends of the umbilical cord 2 can be tightly fixed on the objective table 1, so that the umbilical cord 2 is not easy to move, and the subsequent cutting process is facilitated.
As an example, two side plates 31 of the supporting structure 3 are each provided with a vertical strip-shaped through hole 312, two ends of the grid-shaped blade 44 are each connected with a T-shaped slider 5 corresponding to the strip-shaped through hole 312, and the T-shaped slider 5 passes through the strip-shaped through holes 312 to limit the moving range of the grid-shaped blade 44.
It should be noted that, the two ends of the grid-shaped blade 44 are further limited by the design of the slider-through hole, so that the grid-shaped blade can be effectively ensured to move only along a vertical path in the pressing and rebounding processes, and the cutting effect is prevented from being influenced by the movement in other directions.
By way of example, the support structure 3 is detachably connected to the object table 1.
As an example, the length b and the width c of the lattice voids 441 formed by the lattice-shaped blade 44 are both 1 mm.
By way of example, the mesh blade 44 comprises a 304 stainless steel blade.
It should be noted that the total number of the lattice and the total size of the lattice blades 44 are set according to the size of the umbilical cord 2 and the actual cutting requirement, and are not described herein.
As an example, the device further includes an ejection structure 6, the ejection structure 6 includes a flat plate 61 and a plurality of protrusions 62, the flat plate 61 is fixed in the support structure 3 and located above the grid-shaped blades 44, the flat plate 61 is provided with a circular hole 611 for the straight rod 42 to pass through, the plurality of protrusions 62 are disposed on the lower surface of the flat plate 61, and are in one-to-one correspondence with the grid gaps formed by the grid-shaped blades 44, and are used for ejecting the umbilical cord tissues cut in the grid gaps 441, and the correspondence is shown in fig. 5.
By arranging the ejection structure 6, in the rebounding process after the grid-shaped blade 44 is cut, the protrusion 62 of the ejection structure 6 is used for ejecting the umbilical cord tissue in the grid gap 441 of the corresponding grid-shaped blade 44, so that the cut umbilical cord tissue is prevented from being stuck in the grid gap 441 and cannot be taken out, the waste of the umbilical cord tissue can be effectively reduced, and the cut sample can be fully utilized.
As an example, the flat plate 61 is fixedly connected to the top plate 32 of the supporting structure 3 through a hollow cylinder 612, and the straight rod 42 is movably inserted in the hollow cylinder 612.
As an example, the protrusions 62 of the ejection structure 6 include cylindrical protrusions and/or prismatic protrusions.
It should be noted that the protrusion 62 has a cylindrical structure, so that during the process of ejecting the umbilical cord tissue, the contact surface between the protrusion 62 and the umbilical cord tissue is a plane, thereby ensuring the integrity of the ejected umbilical cord tissue and avoiding the umbilical cord tissue from being unnecessarily damaged due to sharp contact, as shown in fig. 5, in which the protrusion 62 has a cylindrical shape.
It should be noted that, when using the device, firstly, the umbilical cord 2 is fixed on the object stage 1 by using the two grooves 311 of the supporting structure 3, the pressing plate 41 is pressed to make the grid-shaped blade 44 driven by the straight rod 42 move downwards to cut the umbilical cord 2, the grid-shaped blade 44 is brought back to the original position by the springback action generated by the spring 43 after the cutting, during the springback process, the protrusion 62 of the ejecting structure 6 ejects the cut umbilical cord tissue in the grid gap 441 of the corresponding grid-shaped blade 44, and finally, the high-quality cut umbilical cord tissue can be collected.
To sum up, the utility model provides a cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece, the device is fixed the umbilical cord on the objective table through the recess in the bearing structure, adopts the resilience cutting structure who takes latticed blade as the main to cut the umbilical cord, once presses and can accomplish the cutting, can obtain the high quality umbilical cord tissue of even size, shear plane rule rapidly in the short time, and in view of the cutting time shortens greatly, has avoided the serious loss of umbilical cord tissue liquid, has effectively improved the survival rate of cell, has further guaranteed the later stage stem cell acquisition volume; meanwhile, the ejecting structure is further arranged in the device, and in the rebounding process after the grid-shaped blade is cut, the protrusions of the ejecting structure can eject the umbilical cord tissues in the grid gaps of the corresponding grid-shaped blade, so that the cut umbilical cord tissues are prevented from being jammed in the grid gaps and cannot be taken out, the waste of the umbilical cord tissues is reduced, and the cut samples are fully utilized. Therefore, the utility model effectively overcomes various defects in the prior art and has high industrial utilization value.
The above embodiments are merely exemplary to illustrate the structure and efficacy of the present invention, and are not intended to limit the present invention. Modifications and variations can be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which may be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
Claims (10)
1. A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece, its characterized in that, the device includes:
an object stage;
the supporting structure is arranged above the objective table and comprises two side plates and a top plate, the two side plates and the top plate are integrated to form a n-shaped bending plate, the bottoms of the two side plates are provided with grooves, and the top plate is provided with a round hole; and
the cutting structure comprises a pressure plate, a straight rod, a spring and a latticed blade, wherein the straight rod is inserted into the round hole of the top plate, the pressure plate is arranged at the top end of the straight rod, the spring is sleeved on the outer side of the straight rod between the pressure plate and the top plate, and the latticed blade is fixed at the bottom end of the straight rod.
2. The apparatus for cutting umbilical cord tissue mass during umbilical cord mesenchymal stem cell culture according to claim 1, wherein the bottom groove of the side plate of the support structure has a height dimension smaller than the height of the umbilical cord.
3. The apparatus for cutting umbilical cord tissue mass during umbilical cord mesenchymal stem cell culture according to claim 1, wherein the distance between the grooves at the bottom of the two side plates of the support structure is less than the length of the umbilical cord.
4. The device for cutting the umbilical cord tissue block in the umbilical cord mesenchymal stem cell culture process according to claim 1, wherein two side plates of the support structure are both provided with a vertical strip-shaped through hole, two ends of the latticed blade are both connected with a T-shaped sliding block corresponding to the strip-shaped through hole, and the T-shaped sliding block penetrates through the strip-shaped through hole.
5. The device for cutting the umbilical cord tissue mass in the umbilical cord mesenchymal stem cell culture process according to claim 1, wherein the support structure is detachably connected with the stage.
6. The apparatus for cutting umbilical cord tissue mass during umbilical cord mesenchymal stem cell culture according to claim 1, wherein the length and width of the mesh gap formed by the mesh-shaped blades are both 1 mm.
7. The apparatus for cutting umbilical cord tissue mass during culture of umbilical cord mesenchymal stem cells according to claim 1, wherein the mesh-shaped blade comprises a 304 stainless steel blade.
8. The device for cutting the umbilical cord tissue mass in the umbilical cord mesenchymal stem cell culture process according to claim 1, wherein the device further comprises an ejection structure, the ejection structure comprises a flat plate and a plurality of protrusions, the flat plate is fixed in the support structure and located above the grid-shaped blades, the flat plate is provided with round holes so that the straight rod can pass through, and the plurality of protrusions are arranged on the lower surface of the flat plate and correspond to grid gaps formed by the grid-shaped blades one by one.
9. The device for cutting the umbilical cord tissue mass in the umbilical cord mesenchymal stem cell culture process according to claim 8, wherein the flat plate is fixedly connected with the top plate of the support structure through a hollow cylinder, and the straight rod is movably inserted into the hollow cylinder.
10. The apparatus for cutting umbilical cord tissue pieces during culture of umbilical cord mesenchymal stem cells according to claim 8, wherein the protrusions of the ejection structure comprise cylindrical protrusions and/or prismatic protrusions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022810791.8U CN213829130U (en) | 2020-11-26 | 2020-11-26 | A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022810791.8U CN213829130U (en) | 2020-11-26 | 2020-11-26 | A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece |
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| CN213829130U true CN213829130U (en) | 2021-07-30 |
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| CN202022810791.8U Active CN213829130U (en) | 2020-11-26 | 2020-11-26 | A cutting device that is arranged in umbilical cord mesenchymal stem cell culture process umbilical cord tissue piece |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113967931A (en) * | 2021-10-20 | 2022-01-25 | 张斌 | Umbilical cord tissue cutting machine |
| CN115804856A (en) * | 2023-02-08 | 2023-03-17 | 天津长和生物技术有限公司 | Instrument degassing unit after umbilical cord tissue cutting |
| CN116296687A (en) * | 2023-03-31 | 2023-06-23 | 中国中医科学院医学实验中心 | Tissue sample preparation device and application thereof |
-
2020
- 2020-11-26 CN CN202022810791.8U patent/CN213829130U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113967931A (en) * | 2021-10-20 | 2022-01-25 | 张斌 | Umbilical cord tissue cutting machine |
| CN115804856A (en) * | 2023-02-08 | 2023-03-17 | 天津长和生物技术有限公司 | Instrument degassing unit after umbilical cord tissue cutting |
| CN116296687A (en) * | 2023-03-31 | 2023-06-23 | 中国中医科学院医学实验中心 | Tissue sample preparation device and application thereof |
| CN116296687B (en) * | 2023-03-31 | 2024-09-10 | 中国中医科学院医学实验中心 | Tissue sample preparation device and application thereof |
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