CN213824952U - Portable biological safety laboratory - Google Patents

Abstract

The utility model discloses a mobile biological safety laboratory, which comprises a compartment body, wherein the compartment body is a trailer-type compartment and adopts a semitrailer chassis, the lower end of the compartment body is provided with adjustable support legs for keeping the compartment body horizontal, one side of the compartment body is provided with a plurality of upper vehicle doors, the compartment body is provided with a plurality of externally-mounted sunshades and upper vehicle ladders corresponding to the upper vehicle doors, both sides of the compartment body are provided with side observation windows, the side observation windows are vehicle windows for negative pressure sealing, both lower ends of both sides of the compartment body are provided with skirt cabins, the tail end of the compartment body is provided with a backing camera and a rear landing ladder, the compartment body is internally provided with an experiment assembly for detection and experiment, the utility model can be used for the work of detection of emergency major biological safety events, accident sites, mass nucleic acid detection and the like, and the whole biological safety laboratory is flexible and convenient to move, the lifting loading and unloading are not needed, the use and maintenance cost is low, the space in the vehicle is large, the function partition is complete, and the working efficiency is high.

Description

Portable biological safety laboratory

Technical Field

The utility model relates to a biological assay laboratory environment technical field specifically is a portable biological safety laboratory.

Background

In the past experience of preventing and treating epidemic situations such as SARS, human infection avian influenza, pneumonia and the like, aiming at the pathogen on-site detection and large-scale nucleic acid detection work of epidemic situations outburst habitat, all levels of medical institutions face the problems that fixed facilities are not mobile, and outdoor collection facilities are not convenient and safe, and meanwhile, various mobile laboratories on the market have the defects of high manufacturing cost, complex structure, needing hoisting and deploying of shelter type equipment, and poor maneuverability and convenience.

In response to the above problems, a mobile biosafety laboratory is now being devised.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a portable biological safety laboratory to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme:

the utility model provides a portable biological safety laboratory, includes the railway carriage or compartment body, the railway carriage or compartment body is for the trailer carriage and adopt the semitrailer chassis, the lower extreme of the railway carriage or compartment body is equipped with makes the railway carriage or compartment body keep horizontally adjustable landing leg, one side of the railway carriage or compartment body is equipped with a plurality of doors of going up, be equipped with a plurality of outer hanging sunshade and the last ladder that go up that correspond with the door of going up on the railway carriage or compartment body, the both sides of the railway carriage or compartment body all are equipped with the side observation window, the side observation window is for being used for the sealed door window of negative pressure, the both sides lower extreme of the railway carriage or compartment body all is equipped with the skirt cabin, the both sides in skirt cabin all are equipped with the storing cabin that is used for placing battery, UPS, instrument, experimental provision of the railway carriage or compartment body, the internal experiment subassembly that is used for measuring and experiment that is equipped with.

As a further aspect of the present invention: the experimental assembly comprises an equipment room, a reagent preparation room, a buffer room, a sample preparation room, an amplification analysis room, a U-shaped partition and a decontamination room which are arranged in a box body in sequence, wherein a transverse partition is arranged between the sample preparation room and the amplification analysis room, an access door and a heat dissipation grid are arranged on the equipment room, a clean test table, a refrigerator, a clean workbench and an eye washer are arranged in the reagent preparation room, a blending instrument and a centrifugal machine are arranged on the clean test table, a clean test table and a biological safety cabinet are arranged in the sample preparation room, a plurality of nucleic acid extraction instruments are arranged on the clean test table in the sample preparation room, a floor transfer window positioned below the clean test table in the sample preparation room is arranged on one side of the box body, clean test tables are arranged on two sides in the amplification analysis room, and a plurality of fluorescence PCR amplification instruments are arranged on the clean test table in the amplification analysis room, the amplification analysis chamber is internally provided with a computer system, the decontamination room is internally provided with a clean test stand and an autoclave, the buffer room corresponds to the upper car door and is formed by a three-surface U-shaped partition and a compartment body, a negative-pressure airtight door, a wardrobe and a video monitoring center are arranged in the buffer room, a three-door interlocking system, an auxiliary door closing device and an access control system are arranged in the negative-pressure airtight door, the video monitoring center consists of a camera, a hard disk video recorder and a monitoring screen, the camera is respectively arranged in the reagent preparation chamber, the sample preparation chamber, the amplification analysis chamber and the decontamination chamber in a diagonal manner, the reagent preparation chamber, the sample preparation chamber, the amplification analysis chamber, the decontamination chamber and the buffer chamber are all relatively independent sealed spaces, working seats are arranged in the reagent preparation chamber, the sample preparation chamber, the amplification analysis chamber and the decontamination chamber.

As a further aspect of the present invention: the compartment body is made of a squirrel cage type steel-aluminum composite framework, an aluminum alloy inner plate and an aluminum alloy outer plate, a composite plate-making heat-insulation cabin body and a square cabin production process, a heat-insulation layer and an acid-base-resistant polymer composite material protection layer are arranged on the inner wall of the compartment body, and a PVC floor is arranged on the bottom surface inside the compartment body.

As a further aspect of the present invention: all be equipped with the pass-through box in horizontal wall and the U type wall, the pass-through box is the stainless steel pass-through box that has double door interlocking function, all be equipped with the ultraviolet lamp in the pass-through box.

As a further aspect of the present invention: the negative pressure system comprises a negative pressure device and a fresh air system which are respectively arranged at the bottom end and the top end of the reagent preparation chamber, the sample preparation chamber, the amplification analysis chamber, the decontamination chamber and the buffer chamber, and a filtering and sterilizing device and an air pressure control system are respectively arranged in the negative pressure device and the fresh air system.

As a further aspect of the present invention: the upper car door is provided with an expandable inflatable channel.

As a further aspect of the present invention: the compartment body is internally provided with an ultraviolet disinfection device, a time delay device, a smoke sensing alarm device, a temperature/humidity display device and a fire extinguisher.

As a further aspect of the present invention: the compartment body is internally provided with a safety monitoring system, and the safety monitoring system comprises video monitoring systems of all cabins, pressure monitoring and alarming systems of all cabins, a buffer zone three-door interlocking alarming system and an in-vehicle power supply monitoring and alarming system.

As a further aspect of the present invention: the compartment body is internally provided with a GPS positioning function, a voice talkback function, a cooling and heating air conditioning system and a lighting system.

As a further aspect of the present invention: the carriage body has two power supply modes of alternating current and direct current.

Compared with the prior art, the beneficial effects of the utility model are that:

the utility model discloses not only can be used to work such as the investigation of proruption major biosafety incident, accident scene, group nature nucleic acid detection, moreover the utility model discloses the carriage adopts semi-mounted chassis form, need not be equipped with special bearing truck or traction truck, and the accessible is bought public transport service and is satisfied, and whole flexible, it is convenient to remove, need not to lift by crane the loading and unloading, uses and the maintenance cost is low, and automobile body size is big with the car inner space, and the functional partitioning is complete, can easily satisfy 1500 ~ 3000 inspection requirements of day.

Drawings

Fig. 1 is a schematic diagram of a mobile biosafety laboratory in a right-view structure.

Fig. 2 is a left side view of a mobile biosafety laboratory.

Fig. 3 is a schematic top view of a mobile biosafety laboratory.

Fig. 4 is a rear view of a mobile biosafety laboratory.

Fig. 5 is a schematic structural diagram of a belt tractor in a mobile biological safety laboratory.

Wherein: 1. the system comprises a box body, 101, an equipment room, 1011, an access door, 1012, a heat dissipation grid, 102, a reagent preparation room, 1021, a refrigerator, 1022, a blending instrument, 1023, a centrifuge, 1024, a negative pressure device, 1025, an ultra-clean workbench, 103, a buffer room, 1031, a video monitoring center, 1032, a wardrobe, 104, a sample preparation room, 1041, an eye washer, 1042, a nucleic acid extraction instrument, 1043, a floor transfer window, 1044, a biological safety cabinet, 105, an amplification analysis room, 1051, a computer system, 1052, a work seat, 1053, a fluorescence PCR amplification instrument, 1054, a clean test bench, 106, a U-shaped partition, 1061, a transfer window, 1062, a negative pressure sealing door, 107, a decontamination room, 1071, an autoclave, 108, a transverse partition, 109, a skirt cabin, 110, a reversing camera, 111, a rear climbing ladder, 2, an external sunshade shed, 3, an upper door, 4, an upper ladder, 5 and supporting legs.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-5, in an embodiment of the present invention, a mobile biological safety laboratory includes a box body 1, wherein the box body 1 is a trailer-type box and employs a special semi-trailer chassis to meet traction requirements of a general tractor, such that the device can be moved more flexibly and conveniently, the lower end of the box body 1 is provided with adjustable legs 5 for keeping the box body 1 horizontal, one side of the box body 1 is provided with a plurality of upper vehicle doors 3, the box body 1 is provided with a plurality of externally-mounted shelters 2 and upper vehicle ladders 4 corresponding to the upper vehicle doors 3, two sides of the box body 1 are provided with side observation windows 1064, the side observation windows 1064 are special windows for negative pressure sealing, the lower ends of two sides of the box body 1 are provided with skirt cabins 109, two sides of the skirt cabins 109 are provided with storage cabins for placing storage batteries, UPSs, tools, accessories for experimental tests, the tail end of the carriage body 1 is provided with the reversing camera 110 and the rear overhead ladder 111, so that the carriage body 1 does not need to be provided with a special carrying truck or a traction truck, can be met by purchasing public transportation service, is flexible and flexible in whole, convenient to move, free of hoisting, loading and unloading, low in use and maintenance cost and convenient to use;

the utility model discloses a kit for detecting and analyzing nucleic acid in the human body, be equipped with the experimental subassembly that is used for detection and experiment in railway carriage or compartment 1, the experimental subassembly is including establishing equipment room 101, reagent preparation room 102, cushion room 103, sample preparation room 104, amplification analysis room 105, U type wall 106 and washing room 107 in the railway carriage or compartment 1 in proper order, be equipped with cross partition 108 between sample preparation room 104 and the amplification analysis room 105, be equipped with access door 1011 and heat dissipation grid 1012 on the equipment room 101, equipment room 101 adopts the sound insulation and heat insulation technique to handle, so can be convenient for equipment maintenance and heat dissipation, be equipped with clean test bench 1054, refrigerator 1021, superclean bench 1025 and eyewash ware 1041 in the reagent preparation room 102, be equipped with mixing appearance 1023 and centrifuge on clean test bench 1054, be equipped with clean test bench 1054 and biological safety cabinet 1044 in the sample preparation room 104, be equipped with a plurality of nucleic acid extraction appearance 1042 on clean test bench 1054 in the sample preparation room 104, a floor transfer window 1043 positioned below a clean test stand 1054 in the sample preparation chamber 104 is arranged on one side of the carriage body 1, so that a person inside and outside the vehicle can conveniently transfer a sample or sample, the clean test stands 1054 are arranged on two sides in the amplification analysis chamber 105, a plurality of fluorescent PCR amplification instruments 1053 are arranged on the clean test stands 1054 in the amplification analysis chamber 105, a computer system 1051 is arranged in the amplification analysis chamber 105, the clean test stands 1054 and an autoclave 1071 are arranged in the decontamination chamber 107, the buffer chamber 103 corresponds to the upper vehicle door 3, the buffer chamber 103 is enclosed by a three-sided U-shaped partition 106 and the carriage body 1, a negative pressure airtight door 1062, a wardrobe 1032 and a video monitoring center 1031 are arranged in the buffer chamber 103, a three-door interlocking system, an auxiliary door closing device and an entrance guard system are arranged in the negative pressure airtight door 1062, and the three-door interlocking system only allows 1 negative pressure airtight door 1062 to be opened, the access control system can only allow personnel to enter, and can be automatically closed when the personnel leave, the video monitoring center 1031 consists of a camera, a hard disk video recorder and a monitoring screen, the camera is diagonally and respectively arranged in a reagent preparation chamber 102, a sample preparation chamber 104, an amplification analysis chamber 105 and a decontamination chamber 107, the reagent preparation chamber 102, the sample preparation chamber 104, the amplification analysis chamber 105, the decontamination chamber 107 and the buffer chamber 103 are relatively independent sealed spaces, and working seats 1052 are arranged in the reagent preparation chamber 102, the sample preparation chamber 104, the amplification analysis chamber 105 and the decontamination chamber 107, so that the device can be used for work such as emergency major biological safety events, detection of accident sites, mass nucleic acid detection and the like, meanwhile, the size of a vehicle body and the space in the vehicle are large, the function partition is complete, and the inspection requirements of 1500-3000 parts per day can be easily met, the use is greatly convenient;

the compartment body 1 is made of a squirrel cage type steel-aluminum composite framework, an aluminum alloy inner plate and outer plate, a composite plate-making heat-insulation cabin body and a square cabin production process, the inner wall of the compartment body 1 is provided with a heat-insulation layer and an acid-base-resistant polymer composite material protection layer, so that the compartment body 1 has the characteristics of wear resistance, impact resistance, infiltration resistance, ultraviolet resistance, flame retardance and the like, and the inner bottom surface of the compartment body 1 is provided with a PVC floor, so that the bottom surface of the compartment body 1 is fireproof, antibacterial, wear-resistant and anti-skid;

a transfer window 1061 is arranged in each of the transverse partition 108 and the U-shaped partition 106, the transfer window 1061 is a stainless steel transfer window with a double-door interlocking function, and ultraviolet lamps are arranged in the transfer windows 1061;

negative pressure systems are arranged in the reagent preparation chamber 102, the sample preparation chamber 104, the amplification analysis chamber 105, the decontamination chamber 107 and the buffer chamber 103, the negative pressure systems comprise a negative pressure device 1024 and a fresh air system which are respectively arranged at the bottom end and the top end of the reagent preparation chamber 102, the sample preparation chamber 104, the amplification analysis chamber 105, the decontamination chamber 107 and the buffer chamber 103, a filtering and sterilizing device and an air pressure control system are arranged in the negative pressure device 1024 and the fresh air system, and a two-stage isolation mode is adopted in the carriage body 1, namely a biological safety cabinet 1044+ an isolation protective clothing + directional air flow management, so that air in the carriage body 1 flows to the biological safety cabinet arranged in the middle through the fresh air system and finally flows into a negative pressure exhaust system arranged at the lower part to be exhausted, the air flow turbulence is avoided, and further, the pollution air flow in the biological safety cabinet is prevented from flowing to the laboratory staff when the staff operates;

the upper vehicle door 3 is provided with an expandable inflatable channel, so that the device can be further expanded to be connected with other outdoor facilities such as research laboratories or mobile hospitals;

an ultraviolet disinfection device, a time delay device, a smoke alarm, a temperature/humidity display device and a fire extinguisher are arranged in the carriage body 1;

a safety monitoring system is arranged in the carriage body 1 and comprises video monitoring systems of all cabins, pressure monitoring and alarming systems of all cabins, a buffer zone three-door interlocking alarming system and an in-vehicle power supply monitoring and alarming system, so that the safety of the carriage body 1 can be enhanced;

the compartment body 1 is internally provided with a GPS positioning function, a voice talkback function, a cooling and heating air conditioning system and a lighting system, so that when an emergency situation occurs, the accurate position of the accident site can be quickly found, an emergency ambulance and emergency personnel can quickly and conveniently arrive at the site, meanwhile, the voice talkback function can enable workers in each compartment to communicate with each other and communicate conveniently, the cooling and heating air conditioning system meets the independent regulation requirement of each compartment environment, the height of the whole vehicle is ensured, the compartment body can be selectively provided with a parking cooling and heating air conditioner, all lamps of the lighting system adopt clean lamps, LED light sources and lighting switches to be independently controlled in each area, and the reagent preparation chamber 102, the sample preparation chamber 104, the amplification analysis chamber 105, the decontamination chamber 107 and the buffer chamber 103 are not lower than 300lx and meet the national standard requirement;

the compartment body 1 is provided with an alternating current power supply mode and a direct current power supply mode, the direct current power supply mode is directly provided by an auxiliary storage battery, the alternating current power supply mode can be provided by two modes, one mode is provided by a special external power supply and is provided with an electric interface, the other mode is provided by a vehicle-mounted generator, the generator needs to meet the voltage and power requirements of equipment in a cabin, and multiple paths of AC220V and DC24V power output sockets are reserved on the wall and a workbench of each working area.

The utility model discloses a theory of operation is: the utility model discloses not only can be used to work such as the investigation of proruption major biosafety incident, accident scene, group nature nucleic acid detection, moreover the utility model discloses the carriage adopts semi-mounted chassis form, need not be equipped with special bearing truck or traction truck, and the accessible is bought public transport service and is satisfied, and whole flexible, it is convenient to remove, need not to lift by crane the loading and unloading, uses and the maintenance cost is low, and automobile body size is big with the car inner space, and the functional partitioning is complete, can easily satisfy 1500 ~ 3000 inspection requirements of day.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. A portable biological safety laboratory, includes railway carriage or compartment body (1), its characterized in that: the carriage body (1) is a trailer carriage and adopts a semitrailer chassis, the lower end of the carriage body (1) is provided with an adjustable supporting leg (5) which enables the carriage body (1) to keep horizontal, a plurality of upper vehicle doors (3) are arranged on one side of the carriage body (1), a plurality of externally hung sunshades (2) and upper vehicle ladders (4) corresponding to the upper vehicle doors (3) are arranged on the carriage body (1), side observation windows (1064) are arranged on two sides of the carriage body (1), the side observation windows (1064) are vehicle windows for negative pressure sealing, skirt cabins (109) are arranged at the lower ends of two sides of the compartment body (1), storage cabins for placing storage batteries, UPS, tools, auxiliary equipment for experimental detection and accessories are arranged at two sides of each skirt cabin (109), the terminal of railway carriage or compartment body (1) is equipped with camera (110) and the back ladder (111) of ascending a roof of backing a car, be equipped with the experiment subassembly that is used for detecting and experiment in railway carriage or compartment body (1).

2. A mobile biosafety laboratory according to claim 1, further comprising: the experimental assembly comprises an equipment room (101), a reagent preparation room (102), a buffer room (103), a sample preparation room (104), an amplification analysis room (105), a U-shaped partition (106) and a decontamination room (107) which are sequentially arranged in a carriage body (1), wherein a transverse partition (108) is arranged between the sample preparation room (104) and the amplification analysis room (105), an access door (1011) and a heat dissipation grating (1012) are arranged on the equipment room (101), a clean test bench (1054), a refrigerator (1021), a super clean workbench (1025) and an eye washer (1041) are arranged in the reagent preparation room (102), a mixing instrument (1022) and a centrifugal machine (1023) are arranged on the clean test bench (1054), a clean test bench (1054) and a biological safety cabinet (1044) are arranged in the sample preparation room (104), a plurality of nucleic acid extractors (1042) are arranged on the clean test bench (1054) in the sample preparation room (104), one side of the chamber body (1) is provided with a floor transfer window (1043) located below a clean test bed (1054) in the sample preparation chamber (104), both sides of the interior of the amplification analysis chamber (105) are provided with the clean test beds (1054), the clean test beds (1054) in the amplification analysis chamber (105) are provided with a plurality of fluorescent PCR amplification instruments (1053), the amplification analysis chamber (105) is internally provided with a computer system (1051), the decontamination room (107) is internally provided with the clean test beds (1054) and a high-pressure sterilization pot (1071), the buffer room (103) corresponds to the upper vehicle door (3), the buffer room (103) is formed by enclosing a three-side U-shaped partition (106) and the chamber body (1), the buffer room (103) is internally provided with a negative pressure airtight door (1062), a changing cabinet (1032) and a video monitoring center (1031), and the negative pressure airtight door (1062) is internally provided with a three-door interlocking system, The system comprises an auxiliary door closing device and an access control system, wherein a video monitoring center (1031) is composed of a camera, a hard disk video recorder and a monitoring screen, the camera is diagonally and respectively installed in a reagent preparation chamber (102), a sample preparation chamber (104), an amplification analysis chamber (105) and a decontamination chamber (107), the reagent preparation chamber (102), the sample preparation chamber (104), the amplification analysis chamber (105), the decontamination chamber (107) and a buffer chamber (103) are relatively independent sealed spaces, and a working seat (1052) is arranged in each of the reagent preparation chamber (102), the sample preparation chamber (104), the amplification analysis chamber (105) and the decontamination chamber (107).

3. A mobile biosafety laboratory according to claim 1, further comprising: the box body (1) is made of a squirrel cage type steel-aluminum composite framework, an aluminum alloy inner plate and an aluminum alloy outer plate, a composite plate-making heat-insulation cabin body and a square cabin production process, a heat-insulation layer and an acid and alkali resistant polymer composite material protection layer are arranged on the inner wall of the box body (1), and a PVC floor is arranged on the bottom surface inside the box body (1).

4. A mobile biosafety laboratory according to claim 2, further comprising: all be equipped with pass-through windows (1061) in horizontal wall (108) and the U type wall (106), pass-through windows (1061) are the stainless steel pass-through windows that have the double-door interlocking function, all be equipped with the ultraviolet lamp in pass-through windows (1061).

5. A mobile biosafety laboratory according to claim 2, further comprising: all be equipped with negative pressure system in reagent preparation room (102), sample preparation room (104), amplification analysis room (105), washing and disappearing room (107) and buffering room (103), negative pressure system is including establishing negative pressure device (1024) and the new trend system in reagent preparation room (102), sample preparation room (104), amplification analysis room (105), washing and disappearing room (107) and buffering room (103) bottom and top respectively, all be equipped with in negative pressure device (1024) and the new trend system and filter and kill device and atmospheric pressure control system.

6. A mobile biosafety laboratory according to claim 1, further comprising: the upper vehicle door (3) is provided with an expandable inflatable channel.

7. A mobile biosafety laboratory according to claim 1, further comprising: an ultraviolet disinfection device, a time delay device, a smoke alarm, a temperature/humidity display device and a fire extinguisher are arranged in the carriage body (1).

8. A mobile biosafety laboratory according to claim 1, further comprising: the safety monitoring system is arranged in the carriage body (1) and comprises video monitoring systems of all cabins, pressure monitoring and alarming systems of all cabins, three-door interlocking alarming systems of a buffer area and a power monitoring and alarming system in the vehicle.

9. A mobile biosafety laboratory according to claim 1, further comprising: the compartment body (1) is internally provided with a GPS positioning function, a voice talkback function, a cooling and heating air conditioning system and a lighting system.

10. A mobile biosafety laboratory according to claim 1, further comprising: the carriage body (1) has two power supply modes of alternating current and direct current.

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