CN213337007U - Novel cell film-making manufacturing platform - Google Patents
Novel cell film-making manufacturing platform Download PDFInfo
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- CN213337007U CN213337007U CN202022188335.4U CN202022188335U CN213337007U CN 213337007 U CN213337007 U CN 213337007U CN 202022188335 U CN202022188335 U CN 202022188335U CN 213337007 U CN213337007 U CN 213337007U
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Abstract
The utility model discloses a novel cell slide manufacturing platform, which comprises a workbench, a first temporary storage device, a centrifugal device, a slide dyeing device, a second temporary storage device, a third temporary storage device, a first waste bucket, a second waste bucket, a first waste liquid groove and a second waste liquid groove; the first temporary storage device, the centrifugal device and the slide dyeing device are sequentially arranged on the workbench from left to right; the second temporary storage device is arranged on the workbench at the front side of the first temporary storage device; the third temporary storage device is arranged on the workbench at the front side of the slide dyeing device; the first waste barrel is arranged on the workbench between the second temporary storage device and the third temporary storage device; the second waste material barrel is arranged on the workbench at the right side of the third temporary storage device; the first waste liquid groove is arranged on the workbench between the centrifugal device and the second temporary storage device; the second waste liquid groove is arranged on the workbench at the rear side of the slide dyeing device. The utility model discloses realize accomplishing the cell film-making on same workstation, effectively shorten the film-making time, practice thrift the manpower, improved film-making efficiency.
Description
Technical Field
The utility model relates to a biological system appearance technical field especially relates to a novel cell film-making manufacturing bench.
Background
In the field of clinical medicine, the existence of pathological changes in a human body is often judged by observing cell slices of various tissues of the human body, and the cell slices are prepared by the following steps: sampling, centrifuging, smearing and dyeing, wherein each step is respectively carried out in a work area separated from each other, so that a cell sample needs to be transferred among a plurality of areas, and the time and the labor are consumed; at present, the cell film-making manufacturing installation that can accomplish sample in proper order and keep in, centrifugation, smear and dyeing step has not appeared on the market yet, based on this, the utility model discloses and research and development.
Accordingly, the prior art is deficient and needs improvement.
SUMMERY OF THE UTILITY MODEL
The utility model aims at overcoming the not enough of prior art, providing a novel cell film-making manufacturing platform.
The technical scheme of the utility model as follows:
a novel cell slide manufacturing station, comprising: the glass slide dyeing device comprises a workbench, a first temporary storage device, a centrifugal device, a glass slide dyeing device, a second temporary storage device, a third temporary storage device, a first waste barrel, a second waste barrel, a first waste liquid groove and a second waste liquid groove; the first temporary storage device, the centrifugal device and the slide dyeing device are sequentially arranged on the workbench from left to right, the first temporary storage device is used for temporarily storing a sample, the centrifugal device is used for realizing cell centrifugation, and the slide dyeing device is used for realizing slide dyeing; the second temporary storage device is arranged on the workbench at the front side of the first temporary storage device and is used for temporarily storing the sampling tube; the third temporary storage device is arranged on the workbench at the front side of the slide dyeing device and is used for temporarily storing the centrifuge tube; the first waste barrel is arranged on the workbench between the second temporary storage device and the third temporary storage device and is used for recovering waste sampling tubes; the second waste barrel is arranged on the workbench on the right side of the third temporary storage device and is used for recovering waste centrifuge tubes; the first waste liquid groove is arranged on the workbench between the centrifugal device and the second temporary storage device and is used for recovering sample waste liquid; and the second waste liquid groove is arranged on the workbench at the rear side of the slide dyeing device and is used for recovering dyeing waste liquid.
Further, the first temporary storage device comprises a first mounting frame arranged on the workbench, a sample tube rack detachably arranged on the first mounting frame, and a pressing plate rotatably arranged on the first mounting frame above the sample tube rack; the sample tube rack is provided with a plurality of sample tube holes, each sample tube hole is used for placing a sample bottle containing the sample, and the left side and the right side of the sample tube rack are respectively provided with a handle, so that the sample tube rack is convenient to transfer; sampling holes are formed in the positions, corresponding to the sample tube holes, of the pressing plate and used for being matched with a sample moving device to achieve positioning sampling;
the first mounting frame is provided with limiting devices on the left side and the right side of the pressing plate respectively, and each limiting device consists of a knob fixing block arranged on the first mounting frame and a knob rotatably arranged on the knob fixing block; when in use, the knob is twisted to realize the operation of pressing or releasing the pressing plate.
Further, the centrifugal device comprises a shell, a power mechanism, a rotating mechanism and a plurality of centrifugal pipe frames; the shell is arranged on the workbench on the right side of the first mounting frame, a centrifugal cavity is formed in the shell, the rotating mechanism is arranged in the centrifugal cavity, a plurality of centrifuge tube frames are rotatably arranged on the top of the rotating mechanism, a plurality of centrifuge tube holes are formed in each centrifuge tube frame, each centrifuge tube hole is used for placing a centrifuge tube, and the bottom of the rotating mechanism penetrates out of the shell downwards; the power mechanism is arranged below the shell, and the output end of the power mechanism is connected with the end part of the rotating mechanism, which is positioned outside the shell; the rotating mechanism comprises push-pull assemblies, push-pull pieces are arranged on the inner edge of each centrifuge tube rack, and the push-pull assemblies are used for pushing the push-pull pieces; when in use, the operation of pushing one of the push-pull sheets is realized through the action of the push-pull assembly;
the outer edge of the bottom of each centrifuge tube rack is provided with a gravity pressing block, and each centrifuge tube rack can automatically reset under the action of the gravity pressing block when the centrifugation work is finished;
the shell is provided with a cover plate accommodating groove, and a cover plate is arranged on the cover plate accommodating groove; the cover plate is provided with a grabbing groove for grabbing the cover plate; the apron in snatch groove one side and still be equipped with the observation window, the operating condition of being convenient for operator observation centrifugal chamber.
Furthermore, the rotating mechanism also comprises a rotating shaft, a rotating shaft pipe, a rotating shaft pressing ring, a fixing plate and a rotating plate; the rotating shaft is arranged in the centrifugal cavity, the rotating plate is arranged at the top of the rotating shaft, the rotating plate is uniformly provided with a plurality of mounting bins matched with the number of the centrifuge tube racks, and the centrifuge tube racks are rotatably mounted in the mounting bins; the rotating shaft pressing ring is arranged on the rotating shaft below the rotating plate; the rotating shaft tube is arranged on the rotating shaft below the rotating shaft pressing ring, and the rotating shaft tube is provided with the push-pull assembly; the fixing plate is arranged on the rotating shaft below the rotating shaft tube and is also connected with the shell to play a role of fixing and supporting; the bottom of the rotating shaft penetrates out of the shell downwards and is connected with the output end of the power mechanism;
the rotating plate is provided with a pressure pad above each centrifuge tube rack respectively, and plays a role in limiting the centrifuge tube racks; when in use, the pressure pad realizes the control of the swing direction and angle of the centrifugal tube rack in the centrifugal process.
Furthermore, the push-pull assembly comprises two push-pull devices arranged on two opposite sides of the rotating shaft pipe, a push block connected with the output ends of the two push-pull devices, and a push plate arranged on the push block; when the push plate is used, the push block pulls the push plate to move through the action of the push-pull device connected with the push block.
Furthermore, the power mechanism comprises a servo motor provided with an encoder, a driving wheel, a synchronous belt and a driven wheel; the driven wheel is fixedly arranged at the bottom of the rotating shaft, the servo motor is arranged on one side of the driven wheel, the driving wheel is connected to the output end of the servo motor, and the synchronous belt is arranged on the driving wheel and the driven wheel; when the synchronous belt type electric power transmission device is used, the servo motor pulls the driving wheel connected with the servo motor to rotate, the driving wheel pulls the driven wheel to rotate through the synchronous belt, and therefore the rotating shaft connected with the driven wheel is pulled by the driven wheel to rotate around the axis of the rotating shaft; furthermore, the power mechanism also comprises two fastening devices; two tight setting device respectively in the both sides of hold-in range install in the below of casing, and two tight setting device's position is adjustable, is used for adjusting the elasticity of hold-in range.
Further, the slide staining device comprises a plurality of slide staining components;
each of the slide staining assemblies includes:
the dyeing bottle is hollow, the bottom of the dyeing bottle is provided with an annular bulge and a rubber ring, and two opposite sides of the annular bulge are respectively extended with a lug;
the mounting seat is arranged on the workbench on the right side of the centrifugal device and used for placing a support plate;
the glass slide dyeing device comprises a carrier plate, a plurality of dyeing bottles and a plurality of dyeing pieces, wherein the carrier plate is provided with grooves which are arranged in an array manner and are used for accommodating glass slides, and two inner sides of each groove are provided with buckling positions for buckling annular raised bumps at the bottom of each dyeing bottle;
the annular suction nozzle is inserted into the bottom of the staining bottle and used for sucking staining solution on the slide;
wherein, the two sides of the carrier plate are provided with handles for transferring the carrier plate.
Further, the second temporary storage device comprises a second mounting frame arranged on the workbench at the front side of the first mounting frame and a sampling pipe frame detachably arranged on the second mounting frame; evenly be equipped with a plurality of sample tube holes on the sample tube support, each sample tube hole all is used for keeping in the sampling tube, just be equipped with the handle on the left and right sides of sample tube support respectively, the sample tube support's of being convenient for transfer.
Further, the third temporary storage device comprises a third mounting frame arranged on the workbench at the front side of the mounting seat and a temporary storage pipe frame arranged on the third mounting frame; the pipe support of keeping in is equipped with a plurality of pipe holes of keeping in, each the pipe hole of keeping in all is used for keeping in the centrifuging tube.
By adopting the scheme, the utility model discloses following beneficial effect has:
1. the combined design of the utility model realizes the cell slide of the temporary storage sample, the centrifugation, the smear and the dyeing steps on the same workbench, effectively shortens the slide time, saves the manpower and improves the slide efficiency;
2. the utility model realizes that the centrifuge tube is kept in an inclined state in the feeding process, ensures that the liquid injected into the centrifuge tube can flow into the centrifuge tube along the tube wall, has smooth feeding, is not easy to cause liquid oscillation, effectively avoids the cells from being dispersed in the upper liquid, effectively reduces the loss of the centrifuged cells, and has good use experience;
3. the utility model realizes the control of the swing direction and angle of the centrifuge tube in the centrifugation process, effectively avoids the damage of the centrifuge tube caused by collision, ensures the integrity of the centrifuge tube and has good centrifugation effect;
4. the encoder in the optimized scheme effectively ensures that the number of turns of the servo motor rotating during each operation is a fixed value, realizes the positioning function of the centrifuge tube rack, namely ensures that the centrifuge tube rack returns to the original position after each centrifugation, and realizes good positioning;
5. the application of the tightening device in the preferred scheme can effectively regulate and control the tightness of the synchronous belt, and ensure the transmission accuracy;
6. the application of pressure pad in the preferred scheme can guarantee that after the centrifugation, each centrifuge tube rack all is in the coplanar, when the centrifugation, does not harm each centrifuge tube rack when the centrifugation, and the face leanin for the synchronous slope of centrifuging tube, the bottom that is in the centrifuging tube behind the cell centrifugation.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
FIG. 1 is a three-dimensional structure of the present invention;
FIG. 2 is an enlarged view of FIG. 1 at A;
FIG. 3 is a perspective view of the centrifuge of the present invention;
fig. 4 is a three-dimensional structure view of the centrifugal device of the present invention with the housing and the power mechanism removed;
fig. 5 is a side view of the centrifugal device with the housing and the power mechanism removed;
FIG. 6 is a cross-sectional view taken at view A-A of FIG. 4;
FIG. 7 is a three-dimensional structure of the centrifuge device with the casing, the centrifuge tube rack, the centrifuge tube and the power mechanism removed;
fig. 8 is a three-dimensional structure diagram of the power mechanism in the centrifugal device of the present invention.
The objects, features and advantages of the present invention will be further described with reference to the accompanying drawings.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
In the description of the present invention, unless expressly stated or limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning permanently connected, detachably connected, or integral to one another; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
In the description of the present embodiment, the terms "upper", "lower", "left", "right", "front", "rear", and the like are used in the orientation or positional relationship shown in the drawings only for convenience of description and simplicity of operation, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and therefore should not be construed as limiting the present invention. Furthermore, the terms "first", "second", and "third" are used only for descriptive purposes and are not intended to have any special meaning.
Referring to fig. 1 to 8, the present invention provides a novel cell slide manufacturing platform, which comprises a workbench 1, a first temporary storage device, a centrifugal device, a slide dyeing device, a second temporary storage device, a third temporary storage device, a first waste tank 2, a second waste tank 3, a first waste liquid tank 4 and a second waste liquid tank 5; the first temporary storage device, the centrifugal device and the slide dyeing device are sequentially arranged on the workbench 1 from left to right, the first temporary storage device is used for temporarily storing samples, the centrifugal device is used for realizing cell centrifugation, and the slide dyeing device is used for realizing slide dyeing; the second temporary storage device is arranged on the workbench 1 at the front side of the first temporary storage device and is used for temporarily storing the sampling tube; the third temporary storage device is arranged on the workbench 1 at the front side of the slide dyeing device and is used for temporarily storing the centrifuge tube; the first waste barrel 2 is arranged on the workbench 1 between the second temporary storage device and the third temporary storage device and is used for recovering waste sampling tubes; the second waste barrel 3 is arranged on the workbench 1 at the right side of the third temporary storage device and is used for recovering waste centrifuge tubes; the first waste liquid groove 4 is arranged on the workbench 1 between the centrifugal device and the second temporary storage device and is used for recovering sample waste liquid; and the second waste liquid groove 5 is arranged on the workbench 1 at the rear side of the slide dyeing device and is used for recovering dyeing waste liquid.
In this embodiment, the first temporary storage device comprises a first mounting frame 6 arranged on the workbench 1, a sample tube rack 7 detachably arranged on the first mounting frame 6, and a pressing plate 8 rotatably arranged on the first mounting frame 6 above the sample tube rack 7; a plurality of sample tube holes are uniformly formed in the sample tube frame 7, each sample tube hole is used for placing a sample bottle containing a sample, and handles are respectively arranged on the left side and the right side of the sample tube frame 7, so that the sample tube frame 7 can be conveniently transferred; sampling holes are formed in the positions, corresponding to the sample tube holes, of the pressing plate 8 and used for being matched with a sample moving device to achieve positioning sampling;
further, first mounting bracket 6 in 8 left and right sides of clamp plate are equipped with stop device 9 respectively, each stop device 9 by install in knob fixed block on first mounting bracket 6 with rotatably install in knob on the knob fixed block constitutes, through the wrench movement during the use the knob comes to realize compressing tightly or releases clamp plate 8 to the spacing operation of realization to clamp plate 8.
In this embodiment, the centrifugal device includes a housing 10, a power mechanism, a rotating mechanism, and a plurality of centrifuge tube racks 11; the shell 10 is arranged on the workbench 1 on the right side of the first mounting frame 6, a centrifugal cavity is arranged in the shell 10, the rotating mechanism is arranged in the centrifugal cavity, a plurality of centrifuge tube frames 11 are rotatably arranged on the top of the rotating mechanism, a plurality of centrifuge tube holes are uniformly arranged on each centrifuge tube frame 11, each centrifuge tube hole is used for placing a centrifuge tube, and the bottom of the rotating mechanism penetrates out of the shell 10 downwards; the power mechanism is arranged below the shell 10, and the output end of the power mechanism is connected with the end part of the rotating mechanism, which is positioned outside the shell 10; the rotating mechanism comprises a push-pull assembly, a push-pull sheet 12 is arranged on the inner edge of each centrifuge tube rack 11, and the push-pull assembly is used for pushing the push-pull sheet 12; when the centrifugal liquid feeder is used, the push-pull piece 12 is pushed to push one of the push-pull pieces 12 through the action of the push-pull assembly, so that the push-pull piece 12 can drive the centrifugal pipe frame 11 connected with the push-pull piece to incline towards the inner side of the rotating mechanism, liquid injected into the centrifugal pipe can slowly flow into the centrifugal pipe along the pipe wall of the centrifugal pipe, the feeding is smooth, liquid oscillation is not easily caused, cells are prevented from being dispersed in each liquid layer, the loss of the centrifuged cells is reduced, and the practical use experience is good;
the rotating mechanism also comprises a rotating shaft 13, a rotating shaft pipe 14, a rotating shaft pressing ring 15, a fixing plate 16 and a rotating plate 17; the rotating shaft 13 is arranged in the centrifugal cavity, the rotating plate 17 is arranged at the top of the rotating shaft 13, the rotating plate 17 is uniformly provided with a plurality of mounting bins matched with the centrifuge tube racks 11 in number, and the centrifuge tube racks 11 are rotatably mounted in each mounting bin; the rotating shaft pressing ring 15 is arranged on the rotating shaft 13 below the rotating plate 17; the rotating shaft tube 14 is arranged on the rotating shaft 13 below the rotating shaft pressing ring 15, and the pushing and pulling assembly is arranged on the rotating shaft tube 14; the fixing plate 16 is disposed on the rotating shaft 13 below the rotating shaft tube 14, and the fixing plate 16 is further connected to the housing 10 to play a role of fixing and supporting; the bottom of the rotating shaft 13 penetrates out of the shell 10 downwards and is connected with the output end of the power mechanism;
the rotating plate 17 is provided with a pressure pad 18 above each centrifuge tube rack 11 respectively, and plays a role in limiting the centrifuge tube racks 11; when the centrifugal tube rack is used, the swing direction and angle of the centrifugal tube rack 11 in the centrifugal process are controlled through the pressure pad 18, collision between centrifugal tubes on the two oppositely arranged centrifugal tube racks 11 is effectively avoided, and the integrity of the centrifugal tubes is ensured;
the push-pull assembly comprises two push-pull devices 19 arranged on two opposite sides of the rotating shaft tube 14, a push block 20 connected with the output ends of the two push-pull devices 19, and a push plate 21 arranged on the push block 20; when in use, the push block 20 pulls the push plate 21 to move through the action of the push-pull device 19 connected with the push block, so that the push plate 21 can push and push the pull tab 12; specifically, the push-pull device 19 is a push-pull electromagnet;
the power mechanism comprises a servo motor 22 provided with an encoder, a driving wheel 23, a synchronous belt 24 and a driven wheel 25; the driven wheel 25 is fixedly arranged at the bottom of the rotating shaft 13, the servo motor 22 is arranged at one side of the driven wheel 25, the driving wheel 23 is connected to the output end of the servo motor 22, and the synchronous belt 24 is arranged on the driving wheel 23 and the driven wheel 25; when in use, the servo motor 22 pulls the driving wheel 23 connected with the servo motor to rotate, the driving wheel 23 pulls the driven wheel 25 to rotate through the synchronous belt 24, and therefore the rotating shaft 13 connected with the driven wheel 25 is pulled to rotate around the axis of the rotating shaft; further, the power mechanism further comprises two fastening devices 26; the two fastening devices 26 are respectively arranged below the shell 10 at two sides of the synchronous belt 24, and the positions of the two fastening devices 26 are adjustable, so that the tightness of the synchronous belt 24 can be adjusted, and the transmission accuracy is effectively ensured;
it is worth mentioning that the application of the encoder effectively ensures that the number of turns of the servo motor 22 in each working rotation is a fixed value, thereby ensuring that each centrifuge tube rack 11 returns to the initial position after completing the centrifugal processing and realizing the positioning function of the centrifuge tube rack 11;
the outer edge of the bottom of each centrifuge tube rack 11 is provided with a gravity pressing block 27, and when the centrifugation work is finished, each centrifuge tube rack 11 can automatically reset under the action of the gravity pressing block 27;
a cover plate accommodating groove is formed in the shell 10, and a cover plate 28 is arranged on the cover plate accommodating groove; a grabbing groove 29 is formed in the cover plate 28 and used for grabbing the cover plate 28; the cover plate 28 is further provided with an observation window 30 at one side of the grabbing groove 29, so that an operator can observe the working state in the centrifugal cavity conveniently;
the quantity of centrifuge tube rack 11 is four, and each evenly be equipped with twelve pipe holes on the centrifuge tube rack 11, it is corresponding, the quantity of installation storehouse also is four.
In the present embodiment, the slide staining apparatus includes several slide staining assemblies;
each of the slide staining assemblies includes:
the dyeing bottle is hollow, the bottom of the dyeing bottle is provided with an annular bulge and a rubber ring, and two opposite sides of the annular bulge are respectively extended with a lug;
a mounting seat 31, which is arranged on the workbench 1 at the right side of the centrifugal device, for placing a carrier plate 32;
the carrier plate 32 is provided with grooves 33 arranged in an array, the grooves 33 are used for accommodating glass slides, and two inner sides of each groove 33 are provided with buckling positions 34 used for buckling annular raised bumps at the bottom of the dyeing bottle;
the annular suction nozzle is inserted into the bottom of the staining bottle and used for sucking staining solution on the slide;
wherein, the two sides of the carrier plate 32 are provided with handles 35 for transferring the carrier plate 32;
preferably, the number of slide staining assemblies is two.
In this embodiment, the second temporary storage device comprises a second mounting frame 36 arranged on the workbench 1 at the front side of the first mounting frame 6 and a sampling pipe frame 37 detachably arranged on the second mounting frame 36; evenly be equipped with a plurality of sample tube holes on the sample tube support 37, each sample tube hole all is used for laying the sampling tube to the realization is to the temporary storage of sampling tube, just be equipped with the handle on the left and right sides of sample tube support 37 respectively, the sample tube support 37's of being convenient for transfer.
In this embodiment, the third temporary storage device includes a third mounting frame 38 disposed on the workbench 1 at the front side of the mounting seat 31 and a temporary storage pipe rack 39 disposed on the third mounting frame 38; be equipped with a plurality of temporary storage tube holes on the pipe support 39 of keeping in, each the temporary storage tube hole all is used for laying the centrifuging tube to the realization is to the temporary storage of centrifuging tube.
The utility model discloses working process and principle as follows: firstly, the cover plate 28 is opened, then the centrifuge tube temporarily stored on the temporarily-stored tube rack 39 is placed in the centrifuge tube hole of the centrifuge tube rack 11, and after the centrifuge tube is placed, the external sample moving device is inserted into the sampling tube, so that the combination of the sample moving device and the sampling tube is completed; then, driving the sampling tube to move above the sample tube rack 7 by using a sample moving device, and inserting the sampling tube into a sample bottle on the sample tube rack 7 for sampling; then, the sample moving device is used for driving the sampling tube to move to the upper part of the centrifuge tube rack 11, and the sampling tube is inserted into the centrifuge tube on the centrifuge tube rack 11, so that the sample in the sampling tube can be injected into the centrifuge tube; then, abandoning the used sampling tube on the sample moving device into the first waste material barrel 2, replacing the sampling tube with a new one, and repeating the sampling and sample injecting operations until all the centrifuge tubes are filled with samples, and at the moment, covering the cover plate 28; starting the servo motor 22, rotating the centrifuge tube rack 11 under the driving of the servo motor 22, and rotating the centrifuge tube along with the rotation of the centrifuge tube rack 11; the servo motor 22 stops after rotating to the preset number of turns of the encoder, the centrifugal processing of the centrifugal tube is completed, at the moment, the cover plate 28 is opened, and the centrifugal tube is taken out in sequence; then, the cell sample in the centrifugal tube is transferred to a slide, the slide is placed in a groove 33, a staining bottle is inserted into the groove 33 to rotate, a bump is clamped on a clamping position 34 of the groove 33, a rubber ring seals the space between the staining bottle and the slide, so that staining solution can be dripped into the slide, after sufficient staining, redundant staining solution is sucked away through a needle-shaped suction nozzle, and after multiple times of staining (staining with different colors), a cell slide can be obtained.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the combined design of the utility model realizes the cell slide of the temporary storage sample, the centrifugation, the smear and the dyeing steps on the same workbench, effectively shortens the slide time, saves the manpower and improves the slide efficiency;
2. the utility model realizes that the centrifuge tube is kept in an inclined state in the feeding process, ensures that the liquid injected into the centrifuge tube can flow into the centrifuge tube along the tube wall, has smooth feeding, is not easy to cause liquid oscillation, effectively avoids the cells from being dispersed in the upper liquid, effectively reduces the loss of the centrifuged cells, and has good use experience;
3. the utility model realizes the control of the swing direction and angle of the centrifuge tube in the centrifugation process, effectively avoids the damage of the centrifuge tube caused by collision, ensures the integrity of the centrifuge tube and has good centrifugation effect;
4. the encoder in the optimized scheme effectively ensures that the number of turns of the servo motor rotating during each operation is a fixed value, realizes the positioning function of the centrifuge tube rack, namely ensures that the centrifuge tube rack returns to the original position after each centrifugation, and realizes good positioning;
5. the application of the tightening device in the preferred scheme can effectively regulate and control the tightness of the synchronous belt, and ensure the transmission accuracy;
6. the application of pressure pad in the preferred scheme can guarantee that after the centrifugation, each centrifuge tube rack all is in the coplanar, when the centrifugation, does not harm each centrifuge tube rack when the centrifugation, and the face leanin for the synchronous slope of centrifuging tube, the bottom that is in the centrifuging tube behind the cell centrifugation.
The above description is only exemplary of the present invention and should not be construed as limiting the present invention, and any modifications, equivalents and improvements made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.
Claims (11)
1. A novel cell slide manufacturing station, comprising: the glass slide dyeing device comprises a workbench, a first temporary storage device, a centrifugal device, a glass slide dyeing device, a second temporary storage device, a third temporary storage device, a first waste barrel, a second waste barrel, a first waste liquid groove and a second waste liquid groove; the first temporary storage device, the centrifugal device and the slide dyeing device are sequentially arranged on the workbench from left to right, the first temporary storage device is used for temporarily storing a sample, the centrifugal device is used for realizing cell centrifugation, and the slide dyeing device is used for realizing slide dyeing; the second temporary storage device is arranged on the workbench at the front side of the first temporary storage device and is used for temporarily storing the sampling tube; the third temporary storage device is arranged on the workbench at the front side of the slide dyeing device and is used for temporarily storing the centrifuge tube; the first waste barrel is arranged on the workbench between the second temporary storage device and the third temporary storage device and is used for recovering waste sampling tubes; the second waste barrel is arranged on the workbench on the right side of the third temporary storage device and is used for recovering waste centrifuge tubes; the first waste liquid groove is arranged on the workbench between the centrifugal device and the second temporary storage device and is used for recovering sample waste liquid; and the second waste liquid groove is arranged on the workbench at the rear side of the slide dyeing device and is used for recovering dyeing waste liquid.
2. The novel cell slide manufacturing station according to claim 1, wherein the first temporary storage device comprises a first mounting frame arranged on the workbench, a sample tube frame detachably arranged on the first mounting frame, and a pressing plate rotatably arranged on the first mounting frame above the sample tube frame; the sample tube rack is provided with a plurality of sample tube holes, each sample tube hole is used for placing a sample bottle containing the sample, and the left side and the right side of the sample tube rack are respectively provided with a handle, so that the sample tube rack is convenient to transfer; sampling holes are formed in the positions, corresponding to the sample tube holes, of the pressing plate and used for being matched with a sample moving device to achieve positioning sampling;
the first mounting frame is provided with limiting devices on the left side and the right side of the pressing plate respectively, and each limiting device is composed of a knob fixing block arranged on the first mounting frame and a knob rotatably arranged on the knob fixing block.
3. The novel cell slide manufacturing table according to claim 2, wherein the centrifuge device comprises a housing, a power mechanism, a rotation mechanism, and a plurality of centrifuge tube racks; the shell is arranged on the workbench on the right side of the first mounting frame, a centrifugal cavity is formed in the shell, the rotating mechanism is arranged in the centrifugal cavity, a plurality of centrifuge tube frames are rotatably arranged on the top of the rotating mechanism, a plurality of centrifuge tube holes are formed in each centrifuge tube frame, each centrifuge tube hole is used for placing a centrifuge tube, and the bottom of the rotating mechanism penetrates out of the shell downwards; the power mechanism is arranged below the shell, and the output end of the power mechanism is connected with the end part of the rotating mechanism, which is positioned outside the shell; the rotating mechanism comprises push-pull assemblies, push-pull pieces are arranged on the inner edges of the centrifuge tube racks, and the push-pull assemblies are used for pushing the push-pull pieces.
4. The novel cell slide manufacturing table according to claim 3, wherein the rotating mechanism further comprises a rotating shaft, a rotating shaft tube, a rotating shaft pressing ring, a fixing plate and a rotating plate; the rotating shaft is arranged in the centrifugal cavity, the rotating plate is arranged at the top of the rotating shaft, the rotating plate is uniformly provided with a plurality of mounting bins matched with the number of the centrifuge tube racks, and the centrifuge tube racks are rotatably mounted in the mounting bins; the rotating shaft pressing ring is arranged on the rotating shaft below the rotating plate; the rotating shaft tube is arranged on the rotating shaft below the rotating shaft pressing ring, and the rotating shaft tube is provided with the push-pull assembly; the fixing plate is arranged on the rotating shaft below the rotating shaft tube and is also connected with the shell to play a role of fixing and supporting; the bottom of the rotating shaft penetrates out of the shell downwards and is connected with the output end of the power mechanism;
the rotor plate is equipped with the pressure pad respectively in each centrifuge tube rack top, to centrifuge tube rack plays a limiting displacement.
5. The novel cell slide manufacturing station according to claim 4, wherein the push-pull assembly comprises two push-pull devices disposed on opposite sides of the shaft tube, a push block connected to output ends of the two push-pull devices, and a push plate disposed on the push block.
6. The novel cell slide making table according to claim 4, wherein the power mechanism comprises a servo motor provided with an encoder, a driving wheel, a synchronous belt and a driven wheel; the driven wheel is fixedly installed at the bottom of the rotating shaft, the servo motor is installed on one side of the driven wheel, the driving wheel is connected to the output end of the servo motor, and the synchronous belt is installed on the driving wheel and the driven wheel.
7. The novel cytological slide preparation and manufacturing station of claim 1, wherein the slide staining apparatus comprises a plurality of slide staining assemblies;
each of the slide staining assemblies includes:
the dyeing bottle is hollow, the bottom of the dyeing bottle is provided with an annular bulge and a rubber ring, and two opposite sides of the annular bulge are respectively extended with a lug;
the mounting seat is arranged on the workbench on the right side of the centrifugal device and used for placing a support plate;
the glass slide dyeing device comprises a carrier plate, a plurality of dyeing bottles and a plurality of dyeing pieces, wherein the carrier plate is provided with grooves which are arranged in an array manner and are used for accommodating glass slides, and two inner sides of each groove are provided with buckling positions for buckling annular raised bumps at the bottom of each dyeing bottle;
the annular suction nozzle is inserted into the bottom of the staining bottle and used for sucking staining solution on the slide;
wherein, the two sides of the carrier plate are provided with handles for transferring the carrier plate.
8. The novel cell slide manufacturing station according to claim 2, wherein the second temporary storage device comprises a second mounting frame arranged on the workbench at the front side of the first mounting frame and a sampling tube frame detachably arranged on the second mounting frame; evenly be equipped with a plurality of sample tube holes on the sample tube support, each sample tube hole all is used for keeping in the sampling tube, just be equipped with the handle on the left and right sides of sample tube support respectively, the sample tube support's of being convenient for transfer.
9. The novel cell slide manufacturing table according to claim 3, wherein a gravity pressing block is arranged on the outer edge of the bottom of each centrifuge tube rack, and each centrifuge tube rack can automatically reset under the action of gravity of the gravity pressing block when the centrifugation work is completed;
the shell is provided with a cover plate accommodating groove, and a cover plate is arranged on the cover plate accommodating groove; the cover plate is provided with a grabbing groove for grabbing the cover plate; the apron in snatch groove one side and still be equipped with the observation window, the operating condition of being convenient for operator observation centrifugal chamber.
10. The novel cell slide manufacturing station according to claim 7, wherein the third buffer device comprises a third mounting frame disposed on the workbench at the front side of the mounting seat and a buffer tube frame disposed on the third mounting frame; the pipe support of keeping in is equipped with a plurality of pipe holes of keeping in, each the pipe hole of keeping in all is used for keeping in the centrifuging tube.
11. The novel cell slide manufacturing station of claim 6, wherein the power mechanism further comprises two tightening devices; two tight setting device respectively in the both sides of hold-in range install in the below of casing, and two tight setting device's position is adjustable, is used for adjusting the elasticity of hold-in range.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022188335.4U CN213337007U (en) | 2020-09-29 | 2020-09-29 | Novel cell film-making manufacturing platform |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022188335.4U CN213337007U (en) | 2020-09-29 | 2020-09-29 | Novel cell film-making manufacturing platform |
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| Publication Number | Publication Date |
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| CN213337007U true CN213337007U (en) | 2021-06-01 |
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|---|---|---|---|
| CN202022188335.4U Active CN213337007U (en) | 2020-09-29 | 2020-09-29 | Novel cell film-making manufacturing platform |
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| CN (1) | CN213337007U (en) |
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