CN213283561U - Big mouse brain stereotaxic apparatus convenient to adjust fixedly - Google Patents
Big mouse brain stereotaxic apparatus convenient to adjust fixedly Download PDFInfo
- Publication number
- CN213283561U CN213283561U CN202021599206.8U CN202021599206U CN213283561U CN 213283561 U CN213283561 U CN 213283561U CN 202021599206 U CN202021599206 U CN 202021599206U CN 213283561 U CN213283561 U CN 213283561U
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- plate
- fixing
- adjusting
- sliding
- adjusting screw
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- 210000004556 brain Anatomy 0.000 title claims abstract description 26
- 241000699666 Mus <mouse, genus> Species 0.000 claims description 23
- 230000007246 mechanism Effects 0.000 claims description 7
- 210000004283 incisor Anatomy 0.000 claims description 6
- 241000699670 Mus sp. Species 0.000 claims description 3
- 230000002457 bidirectional effect Effects 0.000 claims description 3
- 210000000613 ear canal Anatomy 0.000 claims description 3
- 230000005012 migration Effects 0.000 abstract description 2
- 238000013508 migration Methods 0.000 abstract description 2
- 241000700159 Rattus Species 0.000 description 9
- 210000005036 nerve Anatomy 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 238000011160 research Methods 0.000 description 4
- 238000010171 animal model Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000011705 epilepsy animal model Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000001178 neural stem cell Anatomy 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
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Abstract
The utility model discloses a big mouse brain stereotaxic apparatus convenient to adjust fixedly, including the bed plate, the up end of bed plate is equipped with the loading board, the one end of loading board is equipped with the regulation frame of adjusting the loading board height, be equipped with first spout on two inside walls of regulation frame, two sliding connection has the sliding plate between the first spout. The utility model discloses a set up big mouse loading board on the bed plate, set up the first adjusting screw on the fixed frame through the regulation, the height of convenient regulation loading board, and set up the fine setting fixed plate that can finely tune the lateral distance on the loading board, detain and finely tune the handle, make the fine setting fixed plate carry out lateral shifting, and adjust the ear pole that the symmetry setting can two-way migration be used for fixed big mouse duct through adjusting the third adjusting screw, through the door tooth of adjusting the fixed big mouse of second adjusting screw, make the fixed of big mouse brain swift, and adjust conveniently, the precision is high.
Description
Technical Field
The utility model relates to a scientific research equipment technical field specifically is a big mouse brain stereotaxic apparatus convenient to adjust fixedly.
Background
The brain stereotaxic apparatus, also called a brain fixing device, determines the position of some nerve structures under the cortex by using a three-dimensional coordinate system defined by a mark or other reference points outside the skull so as to carry out directional stimulation, damage, medicine injection, electric potential guidance and other researches on the nerve structures under the condition of non-direct-view exposure. The animal brain stereotaxic apparatus is important research equipment in the fields of nerve anatomy, nerve physiology, neuropharmacology, neurosurgery and the like, is used for performing directional injection, stimulation, damage, electric potential guidance and other operations on a nerve structure, and can be used for the researches of cerebral hemorrhage animal model establishment, Parkinson's disease animal model establishment, epilepsy animal model establishment, intracerebral tumor model establishment, learning and memory, intracerebral neural stem cell transplantation, cerebral ischemia and the like.
At present, the conventional rat and mouse brain stereotaxic instrument is inconvenient to operate and often needs multiple persons to assist in completing when the rat and mouse brain cranium is fixed, the conventional rat and mouse brain stereotaxic instrument is inconvenient to adjust and low in accuracy, the accuracy of an experiment is easily reduced, and the experiment process is influenced, so that the rat and mouse brain stereotaxic instrument convenient to adjust and fix is provided.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a big mouse brain stereotaxic apparatus convenient to adjust fixedly to solve the problem that provides among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
the utility model provides a big mouse brain stereotaxic apparatus convenient to adjust fixedly, includes the bed plate, the up end of bed plate is equipped with the loading board, the one end of loading board is equipped with the regulation frame of adjusting the loading board height, be equipped with first spout on two inside walls of regulation frame, two sliding connection has the sliding plate between the first spout, one end of loading board and one side fixed connection of sliding plate, the up end threaded connection of regulation frame has first adjusting screw, the lower extreme of first adjusting screw and the up end of sliding plate rotate to be connected, the other end that lies in the loading board on the bed plate is equipped with door tooth fixed establishment, be equipped with the duct fixed establishment in the middle of the up end of bed plate of the fixed big mouse's duct, the up end of loading board is equipped with the fine setting fixed plate that can follow the loading board direction and remove.
As a further aspect of the present invention: the door tooth fixing mechanism comprises a clamping plate fixing seat, a fixing clamping plate is arranged on one side face of the clamping plate fixing seat, a notch is formed in one side face of the fixing clamping plate, a movable clamping plate is arranged in the notch, a second adjusting screw is arranged on the upper end face of the clamping plate fixing seat, the lower end of the second adjusting screw is rotatably connected with the upper end face of the movable clamping plate,
as a further aspect of the present invention: the ear canal fixing mechanism comprises ear rods and ear rod fixing seats which are symmetrically arranged, one end of each ear rod is fixedly connected with one side face of each ear rod fixing seat, a second chute is arranged in the middle of the upper end face of the base plate, a lead screw is arranged in the second chute, the two ends of the lead screw are respectively connected onto the two side walls of the base plate through bearings in a rotating manner, one end of the lead screw penetrates through the side wall of the base plate and extends outwards and is connected with a third adjusting screw, the lower ends of the two ear rod fixing seats are connected with sliding blocks, and the two sliding blocks are respectively in threaded connection with the two ends of the lead screw,
as a further aspect of the present invention: the screw rod is a bidirectional threaded rod.
As a further aspect of the present invention: the up end of loading board is equipped with the rectangular channel, the fine setting fixed plate slides and sets up in the rectangular channel, one side of fine setting fixed plate is equipped with the fine setting handle, be equipped with the fine setting mouth on the lateral wall of rectangular channel, the one end of fine setting handle runs through the fine setting mouth of rectangular channel and outwards extends.
As a further aspect of the present invention: the upper end face of the fine adjustment fixing plate is also provided with a plurality of groups of fixing bandages for fixing mice.
Compared with the prior art, the utility model has the advantages of following several aspects:
the utility model discloses a set up big mouse loading board on the bed plate, set up the first adjusting screw on the fixed frame through the regulation, the height of convenient regulation loading board, and set up the fine setting fixed plate that can finely tune the lateral distance on the loading board, detain and finely tune the handle, make the fine setting fixed plate carry out lateral shifting, and adjust the ear pole that the symmetry setting can two-way migration be used for fixed big mouse duct through adjusting the third adjusting screw, through the door tooth of adjusting the fixed big mouse of second adjusting screw, make the fixed of big mouse brain swift, and adjust conveniently, the precision is high.
Drawings
Fig. 1 is a schematic structural diagram of a rat brain stereotaxic apparatus convenient for adjustment and fixation.
Fig. 2 is a schematic sectional structure view of a base plate in a rat brain stereotaxic apparatus convenient for adjustment and fixation.
Fig. 3 is a schematic top view of a bearing plate in the rat brain stereotaxic apparatus convenient for adjustment and fixation.
In the figure: 1. a base plate; 2. an adjusting frame; 3. a first adjusting screw; 4. a sliding plate; 5. a first chute; 6. an ear stem; 7. fixing the clamping plate; 8. a movable splint; 9. a second adjusting screw; 10. a splint fixing seat; 11. a carrier plate; 12. an ear rod fixing seat; 13. a third adjusting screw; 14. a second chute; 15. finely adjusting the fixing plate; 16. a slider; 17. a screw rod; 18. a bearing; 19. a rectangular groove; 20. fixing a bandage; 21. finely adjusting the handle; 22. the mouth is finely adjusted.
Detailed Description
The technical solution of the present patent will be described in further detail with reference to the following embodiments.
Referring to fig. 1-3, a rat brain stereotaxic apparatus convenient to adjust and fix includes a base plate 1, a bearing plate 11 is disposed on an upper end surface of the base plate 1, an adjusting frame 2 for adjusting the height of the bearing plate 11 is disposed at one end of the bearing plate 11, first sliding chutes 5 are disposed on two inner side walls of the adjusting frame 2, a sliding plate 4 is slidably connected between the two first sliding chutes 5, one end of the bearing plate 11 is fixedly connected with one side of the sliding plate 4, a first adjusting screw 3 is threadedly connected to the upper end surface of the adjusting frame 2, a lower end of the first adjusting screw 3 is rotatably connected with the upper end surface of the sliding plate 4, and when the first adjusting screw 3 is rotated, the first adjusting screw 3 and the adjusting frame 2 move relatively, so as to drive the sliding plate 4 to move up and down, and further drive the bearing plate 11 to move up and; the other end that lies in loading board 11 on the bed plate 1 is equipped with incisor teeth fixed establishment, is equipped with the duct fixed establishment of the duct of fixed big mouse in the middle of the up end of bed plate 1, and the up end of loading board 11 is equipped with the fine setting fixed plate 15 that can follow the removal of loading board 11 direction.
Incisor teeth fixed establishment includes splint fixing base 10, be equipped with solid fixed splint 7 on the side of splint fixing base 10, splint fixing base 10 is located solid fixed splint 7 side and is equipped with the notch, and be equipped with movable splint 8 in the notch, the up end of splint fixing base 10 is equipped with second adjusting screw 9, the lower extreme of second adjusting screw 9 and the up end of movable splint 8 rotate to be connected, during the use, place the mouth of big mouse on solid fixed splint 7, rotate second adjusting screw 9, make movable splint 8 be close to or keep away from to solid fixed splint 7, thereby make movable splint 8 and solid fixed splint 7 centre gripping incisor teeth of big mouse.
The ear canal fixing mechanism comprises ear rods 6 and ear rod fixing seats 12 which are symmetrically arranged, one ends of the ear rods 6 are fixedly connected with one side faces of the ear rod fixing seats 12, a second sliding groove 14 is formed in the middle of the upper end face of the base plate 1, lead screws 17 are arranged in the second sliding groove 14, two ends of each lead screw 17 are rotatably connected to two side walls of the base plate 1 through bearings 18 respectively, one end of each lead screw 17 penetrates through the side wall of the base plate 1 to extend outwards and is connected with a third adjusting screw 13, the lower ends of the two ear rod fixing seats 12 are connected with sliders 16, and the two sliders 16 are respectively in threaded connection with two ends of each lead screw 17; the screw rod 17 is a bidirectional threaded rod; when rotating third adjusting screw 13, lead screw 17 then rotates for two sliders 16 on the lead screw 17 are close to each other or keep away from, thereby drive ear post 6 on the ear post fixing base 12 and fix the centre gripping, convenient operation to big mouse's duct.
The up end of loading board 11 is equipped with rectangular channel 19, fine setting fixed plate 15 slides and sets up in rectangular channel 19, one side of fine setting fixed plate 15 is equipped with fine setting handle 21, be equipped with fine setting mouth 22 on the lateral wall of rectangular channel 19, fine setting mouth 22 that rectangular channel 19 was run through to the one end of fine setting handle 21 outwards extends, detain fine setting handle 21, make fine setting fixed plate 15 carry out lateral shifting in rectangular channel 19, make the position of big mouse can with the ear pole, and incisor tooth fixed establishment corresponds.
The upper end surface of the fine adjustment fixing plate 15 is also provided with a plurality of groups of fixing bandages 20 for fixing rats and mice.
The utility model discloses a theory of operation is: the utility model discloses a set up big mouse loading board 11 on the bed plate 1, set up first adjusting screw 3 on the fixed frame through the regulation, convenient regulation loading board 11's height, and set up fine setting fixed plate 15 that can finely tune transverse distance on loading board 11, fine setting handle 21 is detained, make fine setting fixed plate 15 carry out lateral shifting, and adjust the ear pole 6 that the symmetry setting can two-way movement be used for fixed big mouse duct through adjusting third adjusting screw 13, through adjusting the incisor tooth of the fixed big mouse of second adjusting screw 9, make the fixed of big mouse brain swift, and adjust conveniently, the precision is high.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
Although the preferred embodiments of the present patent have been described in detail, the present patent is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present patent within the knowledge of those skilled in the art.
Claims (6)
1. The big and small mouse brain stereotaxic apparatus convenient to adjust and fix is characterized by comprising a base plate (1), wherein a bearing plate (11) is arranged on the upper end face of the base plate (1), an adjusting frame (2) for adjusting the height of the bearing plate (11) is arranged at one end of the bearing plate (11), first sliding grooves (5) are formed in two inner side walls of the adjusting frame (2), a sliding plate (4) is connected between the two first sliding grooves (5) in a sliding manner, one end of the bearing plate (11) is fixedly connected with one side of the sliding plate (4), a first adjusting screw (3) is in threaded connection with the upper end face of the adjusting frame (2), the lower end of the first adjusting screw (3) is rotatably connected with the upper end face of the sliding plate (4), a door tooth fixing mechanism is arranged at the other end, located on the bearing plate (11), of the base plate (1), a auditory canal fixing mechanism for fixing auditory canals of big mice is arranged in the middle of the, the upper end face of the bearing plate (11) is provided with a fine adjustment fixing plate (15) which can move along the direction of the bearing plate (11).
2. The rat brain stereotaxic apparatus convenient to adjust and fix according to claim 1, wherein the incisor fixing mechanism comprises a clamp plate fixing seat (10), a fixing clamp plate (7) is arranged on one side surface of the clamp plate fixing seat (10), a notch is formed in one side surface of the fixing clamp plate (7) of the clamp plate fixing seat (10), a movable clamp plate (8) is arranged in the notch, a second adjusting screw (9) is arranged on the upper end surface of the clamp plate fixing seat (10), and the lower end of the second adjusting screw (9) is rotatably connected with the upper end surface of the movable clamp plate (8).
3. The rat brain stereotaxic apparatus according to claim 1, it is characterized in that the ear canal fixing mechanism comprises an ear rod (6) and an ear rod fixing seat (12) which are symmetrically arranged, one end of the ear rod (6) is fixedly connected with one side surface of the ear rod fixing seat (12), a second sliding groove (14) is arranged in the middle of the upper end surface of the base plate (1), a screw rod (17) is arranged in the second sliding groove (14), two ends of the screw rod (17) are respectively and rotatably connected on two side walls of the base plate (1) through bearings (18), one end of the screw rod (17) penetrates through the side wall of the base plate (1) and extends outwards, and are connected with a third adjusting screw (13), the lower ends of the two ear rod fixing seats (12) are connected with sliding blocks (16), and the two sliding blocks (16) are respectively in threaded connection with the two ends of a screw rod (17).
4. The rat brain stereotaxic apparatus convenient for adjustment and fixation according to claim 3, wherein the screw rod (17) is a bidirectional screw rod.
5. The rat brain stereotaxic apparatus convenient to adjust and fix according to claim 1, wherein a rectangular groove (19) is formed in an upper end face of the bearing plate (11), the fine adjustment fixing plate (15) is slidably disposed in the rectangular groove (19), a fine adjustment handle (21) is disposed on one side of the fine adjustment fixing plate (15), a fine adjustment opening (22) is formed in a side wall of the rectangular groove (19), and one end of the fine adjustment handle (21) penetrates through the fine adjustment opening (22) of the rectangular groove (19) and extends outwards.
6. The rat brain stereotaxic apparatus convenient for adjustment and fixation according to claim 5, wherein the upper end surface of the fine adjustment fixing plate (15) is further provided with a plurality of groups of fixing bandages (20).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021599206.8U CN213283561U (en) | 2020-08-04 | 2020-08-04 | Big mouse brain stereotaxic apparatus convenient to adjust fixedly |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021599206.8U CN213283561U (en) | 2020-08-04 | 2020-08-04 | Big mouse brain stereotaxic apparatus convenient to adjust fixedly |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213283561U true CN213283561U (en) | 2021-05-28 |
Family
ID=76023287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021599206.8U Expired - Fee Related CN213283561U (en) | 2020-08-04 | 2020-08-04 | Big mouse brain stereotaxic apparatus convenient to adjust fixedly |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213283561U (en) |
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2020
- 2020-08-04 CN CN202021599206.8U patent/CN213283561U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210528 |