CN116602785B - Stereotactic instrument - Google Patents
Stereotactic instrument Download PDFInfo
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- CN116602785B CN116602785B CN202310883771.9A CN202310883771A CN116602785B CN 116602785 B CN116602785 B CN 116602785B CN 202310883771 A CN202310883771 A CN 202310883771A CN 116602785 B CN116602785 B CN 116602785B
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- fixing
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- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 37
- 241000699670 Mus sp. Species 0.000 claims abstract description 13
- 238000000429 assembly Methods 0.000 claims abstract description 11
- 230000000712 assembly Effects 0.000 claims abstract description 11
- 238000002474 experimental method Methods 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims abstract description 4
- 230000008569 process Effects 0.000 claims abstract description 4
- 230000007246 mechanism Effects 0.000 claims description 32
- 210000003625 skull Anatomy 0.000 claims description 8
- 238000009434 installation Methods 0.000 claims description 7
- 239000007769 metal material Substances 0.000 claims description 3
- 230000035515 penetration Effects 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 2
- 210000004556 brain Anatomy 0.000 abstract description 10
- 238000002347 injection Methods 0.000 abstract description 8
- 239000007924 injection Substances 0.000 abstract description 8
- 241000862992 Chondromyces Species 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 description 7
- 241000700159 Rattus Species 0.000 description 5
- 230000037237 body shape Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000001179 sorption measurement Methods 0.000 description 3
- 238000010171 animal model Methods 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000027089 Parkinsonian disease Diseases 0.000 description 1
- 206010034010 Parkinsonism Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000000613 ear canal Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011705 epilepsy animal model Methods 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
The invention provides a stereotactic instrument, which relates to the technical field of mouse brain injection, and comprises: the mounting assembly comprises a fixing part and a supporting part, and an arc-shaped groove is formed in the upper end of the fixing part; the lower end surface of the support part is arc-shaped concentric with the arc-shaped groove of the fixing part, so that the lower end surface of the support part can be placed in the arc-shaped groove of the fixing part and can rotate along the center of the arc-shaped groove; the supporting part is adsorbed at the upper end of the arc-shaped groove of the fixing part and is used for supporting the experimental mice, and the mice placed on the supporting part can be conveniently rotated to adjust the angle in the re-experiment process; the three limiting assemblies are connected to the outer sides of the supporting parts in a sliding mode; two spacing subassemblies are fixed the mouse cranium both sides, and another is fixed the cranium front end, has solved the mouse and can't carry out other operations after fixed inside, when needs the injection of polycephalum district, if need special angle, just need take down the mouse, and it is fixed again, spends too long, the easy death problem of mouse.
Description
Technical Field
The invention relates to the technical field of mouse brain injection, in particular to a stereotactic instrument.
Background
The brain stereotactic apparatus is also called brain fixing device, which uses the three-degree coordinate system defined by the mark or other reference point outside the skull to determine the position of some nerve structure under the cortex, so as to conduct the research of directional stimulation, destruction, medicine injection, guiding potential, etc. under the non-direct vision exposure. The animal brain stereotactic instrument is an important research device in the fields of nerve anatomy, nerve physiology, nerve pharmacology, neurosurgery and the like, is used for performing directional injection, stimulation, damage, guiding potential and other operations on a nerve structure, can be used for research on cerebral hemorrhage animal model establishment, parkinsonism animal model establishment, epilepsy animal model establishment, brain tumor model establishment, learning and memory, brain nerve stem cell transplantation, cerebral ischemia and the like, and is used for performing research on nerve direction through a rat and a mouse at present.
At present, a commonly used brain stereotactic apparatus for rats and mice is generally provided with a tooth hook and ear bars at two sides, the tooth of the rats and the mice is fixed on the tooth hook, the ear bars at two sides are aligned with the ear canal of the rats and the mice, and the head of the rats and the mice is fixed by utilizing the three-point positioning principle, so that the subsequent study is convenient.
However, with the current conventional stereotactic apparatus, the mouse cannot perform other operations after being fixed internally, and when the injection in the multiple brain regions is required, if a special angle is required, the mouse needs to be removed and fixed again, which takes too long, and the mouse easily dies.
Disclosure of Invention
The invention provides a stereotactic instrument, which comprises:
the mounting assembly comprises a fixing part and a supporting part, wherein an arc-shaped groove is formed in the upper end of the fixing part and used for mounting the supporting part; the lower end surface of the support part is arc-shaped concentric with the arc-shaped groove of the fixing part, so that the lower end surface of the support part can be placed in the arc-shaped groove of the fixing part and can rotate along the center of the arc-shaped groove; the supporting part is adsorbed at the upper end of the arc-shaped groove of the fixing part and is used for supporting the experimental mice, and the mice placed on the supporting part can be conveniently rotated to adjust the angle in the re-experiment process;
the three limiting assemblies are connected to the outer sides of the supporting parts in a sliding mode; the sliding directions of the two limiting assemblies are collinear, and the sliding direction of the other limiting assembly is perpendicular to the sliding direction of the two limiting assemblies; two collinear limiting assemblies clamp and fix two sides of the mouse skull, and the other limiting assembly fixes the front end of the mouse skull.
Further, the fixed part is the metal material, and the inside of supporting part is provided with magnetic structure, the lower terminal surface of supporting part is placed when the arc inslot of fixed part, magnetic structure adsorbs supporting part and fixed part together for guarantee the stability of installation.
Further, the limiting assembly comprises a limiting part and a driving part; the three limiting parts are respectively and movably connected to the outer sides of the three end faces of the supporting part, and the driving parts are arranged on the limiting parts and are used for controlling the movement of the limiting parts;
further, the motor is arranged in the third driving piece, and a main shaft of the motor of the third driving piece is connected with the connecting arm.
Further, including auxiliary baffle, auxiliary baffle passes through fixed screw fixed connection at the fixing base rear end, and auxiliary baffle's surface is equipped with the scale for show supporting seat rotation angle.
Advantageous effects
According to the invention, the supporting seat is arranged at the upper end of the fixed seat, the lower end surface of the supporting seat is tightly attached to the arc-shaped groove of the fixed seat through the adsorption of the magnetic piece, the mouse is arranged on the supporting seat, the limiting seat is pushed according to the body shape of the mouse, the limiting seat can slide in the mounting slot to roughly adjust the position of the limiting rod, after the limiting part approximately reaches the corresponding position, the position of the jacking column can be finely adjusted through the first driving piece and the second driving piece, so that the position of the cranium of the mouse is accurately limited by the jacking column, meanwhile, the supporting seat is rotated on the fixed seat along the circumferential direction of the arc-shaped groove of the fixed seat, and the mouse on the supporting seat can realize the fine adjustment of the angle;
through above mechanism, through changing automatically controlled, make the fixed more swiftly of mouse, improved work efficiency, when needs special angle to carry out the injection of multiple brain district simultaneously, can directly change the angle of mouse, need not shift the mouse, the effectual survival rate that improves the mouse.
Drawings
In order to more clearly illustrate the technical solution of the embodiments of the present invention, the drawings of the embodiments will be briefly described below.
The drawings described below are only for illustration of some embodiments of the invention and are not intended to limit the invention.
In the drawings:
fig. 1 shows a schematic perspective view of the whole of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 2 shows an exploded view of the whole of the stereotactic apparatus according to an embodiment of the present invention.
Fig. 3 shows a schematic perspective view of a fixing mechanism of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 4 shows a schematic perspective cross-sectional view of a support mechanism of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 5 shows a schematic perspective view of a limiting mechanism of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 6 shows a partially enlarged schematic illustration of a stereotactic apparatus according to an embodiment of the present invention at a shown in fig. 5.
Fig. 7 shows an assembly view of a spacing mechanism of a stereotactic instrument according to an embodiment of the present invention.
Fig. 8 is a schematic perspective view showing a third driving member of the stereotactic apparatus according to an embodiment of the present invention.
Fig. 9 shows an assembly view of a third driver of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 10 shows an assembly view of an auxiliary barrier of a stereotactic apparatus according to an embodiment of the present invention.
Fig. 11 shows a partially enlarged schematic illustration of the stereotactic apparatus according to an embodiment of the present invention at B shown in fig. 10.
List of primary reference numerals
1. A fixing mechanism; 101. a fixing seat; 102. fixing the screw holes;
2. a support mechanism; 201. a support base; 202. installing a slot; 203. a magnetic member; 204. a connecting arm;
3. a limiting mechanism; 301. a limit seat; 302. adjusting a screw; 303. a guide slide block; 304. a limit rod; 305. a top column;
4. a driving mechanism; 401. a first driving member; 402. a guide chute; 403. a second driving member;
5. a third driving member;
6. and an auxiliary baffle.
Detailed Description
In order to make the objects, aspects and advantages of the technical solution of the present invention more clear, the technical solution of the embodiment of the present invention will be clearly and completely described below with reference to the accompanying drawings of the specific embodiment of the present invention.
Examples: please refer to fig. 1 to 11:
as shown in fig. 1 and 2, the present invention proposes a stereotactic apparatus comprising:
the mounting assembly comprises a fixing part and a supporting part, wherein an arc-shaped groove is formed in the upper end of the fixing part and used for mounting the supporting part; the lower end surface of the support part is arc-shaped concentric with the arc-shaped groove of the fixing part, so that the lower end surface of the support part can be placed in the arc-shaped groove of the fixing part and can rotate along the center of the arc-shaped groove; the supporting part is adsorbed at the upper end of the arc-shaped groove of the fixing part and is used for supporting the experimental mice, and the mice placed on the supporting part can be conveniently rotated to adjust the angle in the re-experiment process;
the three limit components are connected to the outer side of the supporting part in a sliding manner; the sliding directions of the two limiting assemblies are collinear, and the sliding direction of the other limiting assembly is perpendicular to the sliding direction of the two limiting assemblies; two collinear limiting components clamp and fix two sides of the mouse skull, and the other limiting component fixes the front end of the mouse skull.
Wherein, as shown in fig. 3, the fixed part is the metal material, and the inside of supporting part is provided with magnetic structure, and when the arc inslot of fixed part was placed to the lower terminal surface of supporting part, magnetic structure was in the same place supporting part and fixed part absorption for guarantee the stability of installation.
As shown in fig. 3, the fixing part is a fixing mechanism 1; the fixing mechanism 1 comprises a fixing seat 101; the fixed seat 101 is made of metal, and an arc-shaped groove is formed in the upper end face of the fixed seat 101; the fixed seat 101 is used for installing the supporting seat 201 through an arc-shaped groove;
two fixing screw holes 102 are respectively formed on the four end faces of the fixing seat 101 and used for assisting in the installation of accessories; the third driving piece 5 and the auxiliary baffle 6 are connected with the fixed seat 101 through the fixed screw hole 102.
As shown in fig. 4, the supporting portion is a supporting mechanism 2, and the supporting mechanism 2 includes a supporting seat 201; the lower end surface of the supporting seat 201 is arc-shaped concentric with the fixed seat 101; a fan-shaped fixing groove is formed in the lower end of the inner part of the supporting seat 201; the end face and two side faces of the first end of the supporting seat 201 are respectively provided with a mounting slot 202, and the mounting slots 202 are of rectangular structures; the mounting slots 202 on the two sides are collinear, and the mounting slots 202 on the end face are perpendicular to the mounting slots 202 on the two sides; the limiting assembly is installed through the installation slot 202, and the stability of the head of the mouse is guaranteed through the fixation in three directions, so that the brain of the mouse is injected;
a magnetic structure is inserted into the arc-shaped groove of the supporting seat 201, and the magnetic structure is a magnetic piece 203; the magnetic piece 203 is a magnet or an electromagnet, and the magnetic piece 203 adsorbs the lower end of the supporting seat 201 and the arc-shaped groove of the fixed seat 101 for limiting and guiding the supporting seat 201; through the adsorption of the magnetic piece 203, the lower end surface of the supporting seat 201 is tightly attached to the arc-shaped groove of the fixed seat 101, meanwhile, when the supporting seat 201 rotates on the fixed seat 101, the supporting seat only rotates along the circumferential direction of the arc-shaped groove of the fixed seat 101, and the mice on the supporting seat 201 can realize fine adjustment of angles;
the rear end of the supporting seat 201 is fixedly connected with a connecting arm 204, and the rotation center of the connecting arm 204 is concentric with the center of the lower end face of the supporting seat 201 and is used for conveniently rotating the supporting seat 201.
As shown in fig. 4, the limiting component comprises a limiting part and a driving part; the three limiting parts are respectively and movably connected to the outer sides of the three end faces of the supporting part, and the driving parts are arranged on the limiting parts and are used for controlling the movement of the limiting parts;
the limiting part is a limiting mechanism 3, and the limiting mechanism 3 comprises a limiting seat 301; the lower end of the limit seat 301 is a rectangular sliding block, and the rectangular sliding block of the limit seat 301 is inserted into the mounting slot 202; the rectangular sliding block of the limit seat 301 slides in the mounting slot 202; the upper end of the rectangular sliding block of the limit seat 301 is provided with a fastening screw for locking the position of the limit seat 301 in the mounting slot 202; when the fastening screw is opened, the limit seat 301 can slide in the mounting slot 202 by pushing the limit seat 301, so that the position of the limit rod 304 is adjusted;
the upper end of the limit seat 301 is provided with a rotary hole, an adjusting screw 302 is inserted into the rotary hole of the limit seat 301, and a guide slide block 303 is sleeved outside the adjusting screw 302; the inside of the guide sliding block 303 is provided with a longitudinal screw hole, and the screw hole of the guide sliding block 303 is matched with the adjusting screw 302; a transverse non-circular through hole is formed in the guide sliding block 303; through the rotation of adjusting screw 302, drive the lift of guide slide 303, and then adjust the height of gag lever post 304, cooperation limit seat 301 realizes the regulation of gag lever post 304 position, makes this device can be applicable to the laboratory mouse of equidimension not.
As shown in fig. 5, the limiting mechanism 3 includes a limiting rod 304, and the shape of the limiting rod 304 is the same as the shape of the non-circular through hole of the guide slider 303; a rack is arranged on the upper end surface of the limiting rod 304, and the tail end of the limiting rod 304 is fixedly connected with a jacking column 305 through a screw; the limiting rod 304 can move up and down under the drive of the guide sliding block 303, and meanwhile, the top column 305 is driven, so that the position of the top column 305 can be adjusted according to the body shape of a mouse;
the top posts 305 of the limiting mechanisms 3 positioned on two sides are ear bars, and the top posts 305 of the limiting mechanisms 3 positioned on the end faces are tooth hooks.
As shown in fig. 6 and 7, the driving unit is a driving mechanism 4; the driving mechanism 4 comprises a first driving piece 401 and a second driving piece 403; a motor is arranged in the first driving piece 401, and the motor of the first driving piece 401 is connected with an upper end gear group; the output end of the upper gear set is connected with the adjusting screw 302 and used for driving the adjusting screw 302 to rotate; the first driving piece 401 drives the adjusting screw rod 302, so that the guide sliding block 303 can move up and down, and the heights of the limiting rod 304 and the top column 305 are adjusted;
a guide chute 402 is fixedly connected to a side surface of the first driving member 401 for limiting and guiding the second driving member 403.
As shown in fig. 7, a guide slider is fixedly connected to a side surface of the second driving member 403, and the guide slider is inserted into the guide chute 402; a motor is arranged in the second driving piece 403, and a gear is fixedly connected to the outer side of a main shaft of the motor of the second driving piece 403; the second driving member 403 is provided with a non-circular through hole which is the same as the guide slider 303; the non-circular through hole of the second driving piece 403 is internally inserted with a limiting rod 304, and the gear of the motor of the second driving piece 403 is meshed with the rack of the limiting rod 304, so as to finely adjust the penetration depth of the limiting rod 304; through first driving piece 401 and second driving piece 403, can finely tune the position of spliced pole 305, make spliced pole 305 restriction mouse skull's position more accurate, cooperate spacing seat 301 to the adjustment of a wide margin of spliced pole 305 penetration depth simultaneously, when guaranteeing that the position is accurate, improved work efficiency.
As shown in fig. 8 and 9, the device comprises a third driving piece 5, the third driving piece 5 is fixedly connected to the front end of the fixing seat 101 through a fixing screw hole 102, a motor is arranged in the third driving piece 5, and a main shaft of the motor of the third driving piece 5 is connected with a connecting arm 204; the rotation of the supporting mechanism 2 can be controlled through the electric drive through the third driving piece 5, so that the manual work is replaced, and the operation is more accurate and efficient.
As shown in fig. 10, the auxiliary baffle 6 is fixedly connected to the rear end of the fixing seat 101 through the fixing screw hole 102, and scales are arranged on the surface of the auxiliary baffle 6 and used for displaying the rotation angle of the supporting seat 201.
Specific use and action of the embodiment: in the invention, the supporting seat 201 is placed at the upper end of the fixed seat 101, the lower end surface of the supporting seat 201 is tightly attached to the arc-shaped groove of the fixed seat 101 through the adsorption of the magnetic piece 203, a mouse is placed on the supporting seat 201, the limiting seat 301 is pushed according to the body shape of the mouse, the limiting seat 301 can slide in the mounting slot 202, the position of the limiting rod 304 is approximately regulated, after the limiting part approximately reaches the corresponding position, the position of the jacking column 305 can be finely regulated through the first driving piece 401 and the second driving piece 403, so that the position of the cranium of the mouse is accurately limited, meanwhile, the supporting seat 201 is enabled to rotate on the fixed seat 101 according to the circumferential direction of the arc-shaped groove of the fixed seat 101, the angle of the mouse on the supporting seat 201 can be finely regulated through the mechanism, the electronic control is changed, the fixing of the mouse is faster and faster through the electronic control, the work efficiency is improved, and when the injection of the multi-brain region is required, the angle of the mouse can be directly changed, the mouse is not required to be transferred, and the survival rate of the mouse is effectively improved.
The foregoing is merely exemplary embodiments of the present invention and is not intended to limit the scope of the invention, which is defined by the appended claims.
Claims (9)
1. A stereotactic apparatus, comprising:
the mounting assembly comprises a fixing part and a supporting part, wherein an arc-shaped groove is formed in the upper end of the fixing part and used for mounting the supporting part; the lower end surface of the support part is arc-shaped concentric with the arc-shaped groove of the fixing part, so that the lower end surface of the support part can be placed in the arc-shaped groove of the fixing part and can rotate along the center of the arc-shaped groove; the supporting part is adsorbed at the upper end of the arc-shaped groove of the fixing part and is used for supporting the experimental mice, and the mice placed on the supporting part can be conveniently rotated to adjust the angle in the re-experiment process;
the supporting part is a supporting mechanism (2), and the supporting mechanism (2) comprises a supporting seat (201); an installation slot (202) is respectively formed in the end face and two side faces of the first end of the supporting seat (201);
the three limiting assemblies are connected to the outer sides of the supporting parts in a sliding mode; the sliding directions of the two limiting assemblies are collinear, and the sliding direction of the other limiting assembly is perpendicular to the sliding direction of the two limiting assemblies; two collinear limiting assemblies clamp and fix two sides of the mouse skull, and the other limiting assembly fixes the front end of the mouse skull; the limiting assembly comprises a limiting part and a driving part; the three limiting parts are respectively and movably connected to the outer sides of the three end faces of the supporting part, and the driving parts are arranged on the limiting parts and are used for controlling the movement of the limiting parts; the limiting part is a limiting mechanism (3), and the limiting mechanism (3) comprises a limiting seat (301) and a limiting rod (304); the lower end of the limit seat (301) is provided with a rectangular sliding block, and the rectangular sliding block of the limit seat (301) is inserted into the mounting slot (202); the rectangular sliding block of the limit seat (301) slides in the mounting slot (202); the upper end of the limit seat (301) is provided with a rotary hole, an adjusting screw (302) is inserted into the rotary hole of the limit seat (301), and a guide sliding block (303) is sleeved outside the adjusting screw (302); the inside of the guide sliding block (303) is provided with a longitudinal screw hole, and the screw hole of the guide sliding block (303) is matched with the adjusting screw rod (302); a transverse non-circular through hole is formed in the guide sliding block (303);
the driving part is a driving mechanism (4); the driving mechanism (4) comprises a first driving piece (401) and a second driving piece (403); a motor is arranged in the first driving piece (401), and the motor of the first driving piece (401) is connected with the upper end gear set; the output end of the upper end gear set is connected with the adjusting screw (302) and used for driving the adjusting screw (302) to rotate; the second driving piece (403) is internally provided with a non-circular through hole which is the same as the guide sliding block (303); a limiting rod (304) is inserted into the non-circular through hole of the second driving piece (403), and a gear of a motor of the second driving piece (403) is meshed with a rack of the limiting rod (304) to finely adjust the penetration depth of the limiting rod (304);
the fixed part is the metal material, and the inside of supporting part is provided with magnetic structure, the lower terminal surface of supporting part is placed when the arc wall of fixed part is inside, magnetic structure adsorbs supporting part and fixed part together for guarantee the stability of installation.
2. A stereotactic apparatus as claimed in claim 1, wherein said fixing part is a fixing mechanism (1); the fixing mechanism (1) comprises a fixing seat (101); the fixing seat (101) is made of metal, and an arc-shaped groove is formed in the upper end face of the fixing seat (101);
two fixing screw holes (102) are respectively formed in the four end faces of the fixing seat (101) and used for assisting in installation of accessories.
3. A stereotactic apparatus as claimed in claim 2, wherein the lower end surface of said support base (201) is arc-shaped concentric with said fixed base (101); the lower end of the inside of the supporting seat (201) is provided with a fan-shaped fixing groove; the mounting slot (202) is of a rectangular structure; the mounting slots (202) of the two side surfaces are collinear, and the mounting slots (202) of the end surfaces are perpendicular to the mounting slots (202) of the two side surfaces;
a magnetic structure is inserted into the arc-shaped groove of the supporting seat (201), and the magnetic structure is a magnetic piece (203); the magnetic piece (203) is a magnet or an electromagnet, and the magnetic piece (203) adsorbs the lower end of the supporting seat (201) and the arc-shaped groove of the fixed seat (101) and is used for limiting and guiding the supporting seat (201);
the rear end of the supporting seat (201) is fixedly connected with a connecting arm (204), and the rotation center of the connecting arm (204) is concentric with the circle center of the lower end face of the supporting seat (201) and is used for conveniently rotating the supporting seat (201).
4. The stereotactic apparatus according to claim 1, wherein the rectangular slider upper end of the limit seat (301) is provided with a fastening screw for locking the position of the limit seat (301) in the mounting slot (202).
5. A stereotactic apparatus as claimed in claim 1, wherein said stop bar (304) has the same shape as the non-circular through hole of the guide slider (303); the upper end face of the limiting rod (304) is provided with a rack, and the tail end of the limiting rod (304) is fixedly connected with a jacking column (305) through a screw; the jacking columns (305) of the limiting mechanisms (3) positioned on two sides are ear rods, and the jacking columns (305) of the limiting mechanisms (3) positioned on the end faces are tooth hooks.
6. A stereotactic apparatus as claimed in claim 1, wherein the side of the first driving member (401) is fixedly connected with a guiding chute (402) for limiting and guiding the second driving member (403).
7. A stereotactic apparatus as claimed in claim 1, wherein a guide slider is fixedly connected to a side of said second driving member (403), and said guide slider is inserted into said guide chute (402); the second driving piece (403) is internally provided with a motor, and the outer side of a main shaft of the motor of the second driving piece (403) is fixedly connected with a gear.
8. A stereotactic apparatus according to claim 3, comprising a third driving member (5), wherein the third driving member (5) is fixedly connected to the front end of the fixing base (101) through a fixing screw hole (102), a motor is arranged in the third driving member (5), and a main shaft of the motor of the third driving member (5) is connected with the connecting arm (204).
9. The stereotactic apparatus according to claim 2, comprising an auxiliary baffle (6), wherein the auxiliary baffle (6) is fixedly connected to the rear end of the fixing base (101) through a fixing screw hole (102), and the surface of the auxiliary baffle (6) is provided with scales for displaying the rotation angle of the supporting base (201).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310883771.9A CN116602785B (en) | 2023-07-19 | 2023-07-19 | Stereotactic instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310883771.9A CN116602785B (en) | 2023-07-19 | 2023-07-19 | Stereotactic instrument |
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| Publication Number | Publication Date |
|---|---|
| CN116602785A CN116602785A (en) | 2023-08-18 |
| CN116602785B true CN116602785B (en) | 2023-10-27 |
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| CN202310883771.9A Active CN116602785B (en) | 2023-07-19 | 2023-07-19 | Stereotactic instrument |
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| CN219207462U (en) * | 2022-08-31 | 2023-06-20 | 苏州药明康德新药开发有限公司 | Fixing device capable of flexibly adjusting eye position of test mouse |
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| JP2008043224A (en) * | 2006-08-11 | 2008-02-28 | Hirotaki Kido | Small animal-fixing device |
| CN111888036A (en) * | 2020-07-31 | 2020-11-06 | 福建医科大学附属第一医院 | Fixing structure of rat brain stereotaxic instrument |
| CN213941053U (en) * | 2020-11-25 | 2021-08-13 | 深圳华阳生物技术有限公司 | Mouse head fixing device |
| CN114869531A (en) * | 2021-11-16 | 2022-08-09 | 温州医科大学附属第一医院 | Multifunctional operating table for injection of living mice |
| CN218391331U (en) * | 2022-04-13 | 2023-01-31 | 广东莱迪生物医药研究院有限公司 | Animal head locater with adjustable it is universal |
| CN219207462U (en) * | 2022-08-31 | 2023-06-20 | 苏州药明康德新药开发有限公司 | Fixing device capable of flexibly adjusting eye position of test mouse |
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| CN116602785A (en) | 2023-08-18 |
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