CN211800901U - Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device - Google Patents
Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device Download PDFInfo
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- CN211800901U CN211800901U CN201922463625.2U CN201922463625U CN211800901U CN 211800901 U CN211800901 U CN 211800901U CN 201922463625 U CN201922463625 U CN 201922463625U CN 211800901 U CN211800901 U CN 211800901U
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Abstract
The application relates to a chemiluminescence analyzer, a substrate bottle assembly of the chemiluminescence analyzer and a substrate liquid extraction device, wherein the chemiluminescence analyzer comprises two substrate bottles for containing the same substrate liquid, a liquid level sensor and a three-way valve, the three-way valve comprises two inlets and an outlet, the two inlets of the three-way valve are respectively communicated with the two substrate bottles for containing the same substrate liquid, and the outlet of the three-way valve is used for outputting the substrate liquid through a pipeline; the liquid level sensors are installed in the substrate bottles and used for detecting the liquid levels in the substrate bottles, and when the liquid levels in the substrate bottles are detected to be lower than a set threshold value, the substrate bottles are switched to another substrate bottle containing the same substrate liquid through the three-way valve to output the substrate liquid. The problem of single bottle of substrate liquid can't satisfy the demand volume of substrate liquid, many bottles of substrate liquid can't effectively carry out the switching of substrate bottle, lead to not inhaling liquid is solved.
Description
Technical Field
The application belongs to the technical field of medical instruments, and particularly relates to a chemiluminescence analyzer, a substrate bottle assembly of the chemiluminescence analyzer and a substrate liquid extracting device of the chemiluminescence analyzer.
Background
The most commonly used method for diagnosing diseases in the medical field, in vitro diagnosis, refers to collecting body fluids, excretions and secretions of a human body to perform chemical composition or chemical reaction analysis so as to judge human body pathological changes, such as chemiluminescence immunoassay.
The chemiluminescence immune analysis method is a new mark immune analysis technique which combines the luminescence analysis and the immune reaction to detect the trace antigen or the antibody, and is an immune analysis method which directly marks the antigen or the antibody by using a chemiluminescence agent. Chemiluminescence analysis is carried out by catalyzing chemiluminescence by a catalyst and oxidizing chemiluminescence by an oxidant to form an excited intermediate, simultaneously emitting photons (hM) when the excited intermediate returns to a stable ground state, and measuring the quantum yield of light by a luminescence signal measuring instrument. The immunoreaction is that luminous substance (generating excited state intermediate under the excitation of reactant) is directly marked on antigen (chemiluminescence immunoassay) or antibody (immunochemiluminescence assay), or enzyme acts on luminous substrate.
In a chemiluminescent reaction, a compound that participates in energy transfer and ultimately releases energy in the form of an emitted photon is called a chemiluminescent agent or luminescent substrate. In the chemiluminescence immunoassay process, a substrate solution is required to be added for chemiluminescence, and the reliability of a test result can be ensured only by ensuring that the liquid amount of the substrate solution is sufficient.
The substrate filling of the chemiluminescence immunoassay is an important stage, the substrate liquid in the chemiluminescence immunoassay provides a reaction environment and a catalyst for chemical reaction, and the liquid quantity state monitoring of the substrate liquid can effectively ensure the sufficiency of reaction conditions and obtain correct test results. In a high-speed luminometer, the consumption of the substrate liquid is high due to high testing speed, the substrate liquid in a single bottle cannot meet the requirement, and the hidden trouble that the substrate liquid cannot be absorbed due to the fact that a plurality of bottles of the substrate liquid cannot be effectively switched is caused.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is: the problem of among the prior art single bottle substrate liquid can't satisfy the demand of substrate liquid, many bottles of substrate liquid can't effectively carry out the switching of substrate bottle, lead to not inhaling liquid is solved.
The utility model provides a technical scheme that its technical problem adopted is:
the utility model provides a substrate bottle component of a chemiluminescence analyzer, which comprises a plurality of groups of substrate bottles for containing substrate liquid, wherein each group of substrate bottles is provided with two substrate bottles for containing the same substrate liquid;
each group of substrate bottles are provided with a substrate bottle switching device, the substrate bottle switching device comprises a liquid level sensor and a three-way valve, the three-way valve comprises two inlets and an outlet, the two inlets of the three-way valve are respectively communicated with the two substrate bottles for containing the same substrate liquid, and one outlet of the three-way valve is used for outputting the substrate liquid through a pipeline;
the liquid level sensors are installed in the substrate bottles and used for detecting the liquid levels in the substrate bottles, and when the liquid levels in the substrate bottles are detected to be lower than a set threshold value, the substrate bottles are switched to another substrate bottle containing the same substrate liquid through the three-way valve to extract the substrate liquid.
Further, according to the utility model discloses the first aspect the substrate bottle subassembly, the three-way valve is two three way solenoid valves, two three way solenoid valves are two and advance a structure.
Further, according to the utility model discloses the substrate bottle subassembly of first aspect, still include alarm circuit for report to the police when detecting the liquid level in the substrate bottle and being less than the settlement threshold value.
Further, according to the utility model discloses first aspect the substrate bottle subassembly, alarm circuit includes the voice broadcast unit for play "substrate liquid is not enough" voice message.
The utility model provides a substrate liquid extracting device of a chemiluminescence analyzer, which comprises a controller, a substrate pump and a substrate bottle component of the first aspect of the utility model;
the controller is connected with a three-way valve in a control mode, an outlet of the three-way valve is communicated with an inlet of the substrate pump, and the controller is used for controlling the three-way valve to act when the liquid level in one of the substrate bottles is lower than a set threshold value.
The third aspect of the present invention provides a chemiluminescence analyzer, comprising the second aspect of the present invention.
The utility model has the advantages that: the utility model discloses a set up substrate bottle auto-change over device, can switch to another bottle of substrate liquid and continue to accomplish the filling of substrate liquid when a bottle of substrate liquid is used up, satisfied the demand of substrate liquid, avoid inhaling the condition emergence that can not reach liquid.
Drawings
The technical solution of the present application is further explained below with reference to the drawings and the embodiments.
Figure 1 is a schematic diagram of a substrate bottle assembly according to an embodiment of the present invention.
Detailed Description
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.
The technical solutions of the present application will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
Example 1
The embodiment provides a substrate bottle assembly of a chemiluminescence analyzer, which comprises a plurality of groups of substrate bottles for containing substrate liquid, wherein each group of substrate bottles is provided with two substrate bottles for containing the same substrate liquid.
Each group of substrate bottles are provided with a substrate bottle switching device, the substrate bottle switching device comprises a liquid level sensor and a three-way valve, the three-way valve comprises two inlets and an outlet, the two inlets of the three-way valve are respectively communicated with the two substrate bottles for containing the same substrate liquid, and one outlet of the three-way valve is used for outputting the substrate liquid through a pipeline;
the liquid level sensors are installed in the substrate bottles and used for detecting the liquid levels in the substrate bottles, and when the liquid levels in the substrate bottles are detected to be lower than a set threshold value, the substrate bottles are switched to another substrate bottle containing the same substrate liquid through the three-way valve to extract the substrate liquid.
In the chemiluminescence analyzer, the substrate solution in each substrate bottle is pumped by a substrate pump, and the pumped substrate solution is filled into a solvent reaction cup to perform photochemical reaction.
The invention will be further described below by taking two sets of substrate bottles shown in FIG. 1 as an example:
as shown in fig. 1, two groups of substrate bottles are provided, wherein the first group of substrate bottles comprises a substrate bottle A1 and a substrate bottle A2 and contains substrate liquid A; the second group of substrate bottles comprises a substrate bottle B1 and a substrate bottle B2, and contain substrate liquid B. Substrate bottle A1 and substrate bottle A2 were switched by a first three-way valve 1, and substrate bottle B1 and substrate bottle B2 were switched by a second three-way valve 2.
Liquid level sensors are respectively arranged in the substrate bottle A1, the substrate bottle A2, the substrate bottle B1 and the substrate bottle B2 and are respectively used for detecting the liquid levels of the substrate liquid in the substrate bottle A1, the substrate bottle A2, the substrate bottle B1 and the substrate bottle B2.
Two inlets of the first three-way valve 1 are respectively communicated with a substrate bottle A1 and a substrate bottle A2, two inlets of the second three-way valve 2 are respectively communicated with a substrate bottle B1 and a substrate bottle B2, an outlet of the first three-way valve 1 outputs substrate liquid A through a corresponding pipeline, and an outlet of the second three-way valve 2 outputs substrate liquid B through a corresponding pipeline.
If the outlet of the first three-way valve 1 is first communicated with the substrate bottle A1, the substrate liquid in the substrate bottle A2 cannot be extracted, and when the liquid level sensor in the substrate bottle A1 detects that the substrate liquid in the substrate bottle A1 is less than the set threshold value, the first three-way valve 1 is operated and switched to the substrate bottle A2 to extract the substrate liquid.
The switching of the substrate bottle B1 and the substrate bottle B2 was the same principle as the switching of the substrate bottle A1 and the substrate bottle A2.
Further, the first three-way valve 1 and the second three-way valve 2 of the present embodiment both adopt two-position three-way solenoid valves with two-in one-out structures.
Taking the substrate bottle A1 and the substrate bottle A2 as examples, the NC (normally closed) inlet end of the two-position three-way electromagnetic valve is communicated with the substrate bottle A1 through a pipeline, and the NO (normally open) inlet end of the two-position three-way electromagnetic valve is communicated with the substrate bottle A2 through a pipeline.
If the two-position three-way electromagnetic valve is in a normally closed type, when a coil of the two-position three-way electromagnetic valve is electrified, a passage from an NC inlet end to an outlet end COM is opened, and a passage from an NO (normally open) inlet end to the outlet end COM is closed. Under the condition that the two-position three-way electromagnetic valve is electrified, the substrate bottle A1 is used for extracting the substrate liquid A, when the liquid level of the substrate liquid in the substrate bottle A1 is detected to be lower than a set threshold value, the corresponding two-position three-way electromagnetic valve is controlled to be powered off, a passage from an NO (normally open) inlet end to an outlet end COM is opened, and the substrate bottle A2 is switched to extract the substrate liquid A.
If the two-position three-way electromagnetic valve is in a normally open type, when a coil of the two-position three-way electromagnetic valve is electrified, a passage from the NO inlet end to the outlet end COM is opened, and a passage from the NC inlet end to the outlet end COM is closed. Under the condition that the two-position three-way electromagnetic valve is powered off, the substrate bottle A1 is used for extracting the substrate liquid A, when the liquid level of the substrate liquid in the substrate bottle A1 is detected to be lower than a set threshold value, the corresponding two-position three-way electromagnetic valve is controlled to be powered on, a passage from an NO (normally open) inlet end to an outlet end COM is opened, and the substrate bottle A2 is switched to extract the substrate liquid A.
Further, the present embodiment also includes an alarm circuit for alarming upon detection of a liquid level in the substrate bottle being below a set threshold. The alarm circuit comprises a voice broadcasting unit and is used for broadcasting voice information of 'substrate liquid is not enough' so as to remind workers to add the substrate liquid.
The utility model discloses a set up substrate bottle auto-change over device, can switch to another bottle of substrate liquid and continue to accomplish the filling of substrate liquid when a bottle of substrate liquid is used up, satisfied the demand of substrate liquid, avoid inhaling the condition emergence that can not reach liquid.
Example 2
This example provides a substrate liquid extraction device for a chemiluminescence analyzer, which comprises a controller, a substrate pump, and the substrate bottle assembly described in example 1.
The controller is connected with a three-way valve in a control mode, an outlet of the three-way valve is communicated with an inlet of the substrate pump, and the controller is used for controlling the three-way valve to act when the liquid level in one of the substrate bottles is lower than a set threshold value.
The three-way valve of this embodiment is a two-position three-way solenoid valve, and the connection and switching of the two-position three-way solenoid valve and the substrate bottle are the same as those of embodiment 1.
The controller can be the PLC controller, and the PLC controller receives level sensor's liquid level information, and when being less than the settlement threshold value, the PLC controller sends control signal, controls two tee bend solenoid valves circular telegrams or cuts off the power supply.
Example 3
The third aspect of the present invention provides a chemiluminescence analyzer, comprising the substrate liquid extraction device according to embodiment 2.
The structure and the principle of the substrate liquid extracting device are the same as those of the embodiment 2.
In light of the foregoing description of the preferred embodiments according to the present application, it is to be understood that various changes and modifications may be made without departing from the spirit and scope of the invention. The technical scope of the present application is not limited to the contents of the specification, and must be determined according to the scope of the claims.
Claims (6)
1. A substrate bottle assembly of a chemiluminescence analyzer comprises a plurality of groups of substrate bottles for containing substrate liquid, each group of substrate bottles is provided with two substrate bottles for containing the same substrate liquid, and the assembly is characterized in that,
each group of substrate bottles are provided with a substrate bottle switching device, the substrate bottle switching device comprises a liquid level sensor and a three-way valve, the three-way valve comprises two inlets and an outlet, the two inlets of the three-way valve are respectively communicated with the two substrate bottles for containing the same substrate liquid, and one outlet of the three-way valve is used for outputting the substrate liquid through a pipeline;
the liquid level sensors are installed in the substrate bottles and used for detecting the liquid levels in the substrate bottles, and when the liquid levels in the substrate bottles are detected to be lower than a set threshold value, the substrate bottles are switched to another substrate bottle containing the same substrate liquid through the three-way valve to extract the substrate liquid.
2. The substrate vial assembly of claim 1, wherein the three-way valve is a two-position three-way solenoid valve having a two-in one-out configuration.
3. The substrate bottle assembly of claim 1, further comprising an alarm circuit for alarming upon detection of a liquid level within the substrate bottle falling below a set threshold.
4. The substrate bottle assembly of claim 3, wherein the alarm circuit comprises a voice announcement unit for announcing "substrate fluid is low".
5. A substrate liquid extracting apparatus for a chemiluminescent analyzer, comprising a controller, a substrate pump, and a substrate bottle assembly according to any one of claims 1 to 4;
the controller is connected with a three-way valve in a control mode, an outlet of the three-way valve is communicated with an inlet of the substrate pump, and the controller is used for controlling the three-way valve to act when the liquid level in one of the substrate bottles is lower than a set threshold value.
6. A chemiluminescent analyzer comprising the substrate liquid extracting device according to claim 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922463625.2U CN211800901U (en) | 2019-12-31 | 2019-12-31 | Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201922463625.2U CN211800901U (en) | 2019-12-31 | 2019-12-31 | Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device |
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| CN211800901U true CN211800901U (en) | 2020-10-30 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112763482A (en) * | 2021-02-03 | 2021-05-07 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
| CN113934236A (en) * | 2021-10-12 | 2022-01-14 | 中元汇吉生物技术股份有限公司 | Substrate device and substrate control system thereof |
-
2019
- 2019-12-31 CN CN201922463625.2U patent/CN211800901U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112763482A (en) * | 2021-02-03 | 2021-05-07 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
| CN112763482B (en) * | 2021-02-03 | 2022-08-09 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
| WO2022165925A1 (en) * | 2021-02-03 | 2022-08-11 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
| CN113934236A (en) * | 2021-10-12 | 2022-01-14 | 中元汇吉生物技术股份有限公司 | Substrate device and substrate control system thereof |
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