CN113934236A - Substrate device and substrate control system thereof - Google Patents
Substrate device and substrate control system thereof Download PDFInfo
- Publication number
- CN113934236A CN113934236A CN202111186006.9A CN202111186006A CN113934236A CN 113934236 A CN113934236 A CN 113934236A CN 202111186006 A CN202111186006 A CN 202111186006A CN 113934236 A CN113934236 A CN 113934236A
- Authority
- CN
- China
- Prior art keywords
- substrate
- assembly
- liquid
- liquid suction
- switching
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000758 substrate Substances 0.000 title claims abstract description 199
- 239000007788 liquid Substances 0.000 claims abstract description 150
- 238000001514 detection method Methods 0.000 claims abstract description 44
- 230000000712 assembly Effects 0.000 claims abstract description 27
- 238000000429 assembly Methods 0.000 claims abstract description 27
- 238000012545 processing Methods 0.000 claims description 27
- 238000007789 sealing Methods 0.000 claims description 16
- 230000005540 biological transmission Effects 0.000 claims description 8
- 238000005213 imbibition Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 description 9
- 238000010521 absorption reaction Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D9/00—Level control, e.g. controlling quantity of material stored in vessel
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Automation & Control Theory (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a substrate device and a substrate control system thereof. The substrate apparatus includes a chassis; a plurality of substrate containers loaded on the substrate rack; a plurality of liquid suction assemblies mounted on the base frame and corresponding to the plurality of substrate containers; a detection unit provided on the plurality of pipette units for detecting the amount of the substrate liquid stored in the plurality of substrate containers; and the switching assembly is connected with the plurality of the liquid absorbing assemblies and is used for switching from the currently communicated liquid absorbing assembly to another liquid absorbing assembly. According to the invention, the liquid suction operation is carried out by one liquid suction component corresponding to one substrate container, the liquid suction condition of the current liquid suction component is detected by the detection component, and when the situation that the storage amount of the substrate liquid in the substrate container corresponding to the current liquid suction component is insufficient is detected, the current liquid suction component is switched to the next liquid suction component by the switching component, so that the liquid suction operation is continuously carried out from the corresponding substrate container by the next liquid suction component, the automatic requirement of a user on the substrate device is met, and the use experience of the user is improved.
Description
Technical Field
The invention relates to the technical field of automation, in particular to a substrate device and a substrate control system thereof.
Background
The existing substrate device is limited by the size of an instrument and the capacity of a substrate container, so that a user often needs to pay attention to the storage capacity of a substrate liquid in the substrate container frequently, the substrate container can be replaced in time to maintain the normal and uninterrupted operation of the instrument, and the requirement of the user on the automation of the substrate device cannot be met.
Disclosure of Invention
The invention aims to provide a substrate device and a substrate control system thereof, and aims to solve the problem that the substrate device in the prior art cannot meet the automation requirements of users.
In order to solve the technical problems, the invention aims to realize the following technical scheme: providing a substrate device comprising:
a bottom shelf;
a plurality of substrate containers loaded on the chassis;
a plurality of pipetting assemblies mounted on said base frame and corresponding to said plurality of substrate containers;
a detection component arranged on the plurality of liquid suction components and used for detecting the substrate liquid storage amount in the plurality of substrate containers;
a switching assembly connected with the plurality of pipetting assemblies for switching from a currently communicating pipetting assembly to another pipetting assembly.
In addition, the present invention also provides a substrate control system, comprising: a control unit, a processing unit and the substrate device, wherein the control unit is connected with the processing unit, the control unit is connected with the switching component, and the processing unit is connected with the detection component;
the processing unit is used for receiving the detection data sent by the detection assembly, analyzing whether the detection data is in a normal threshold range, and if not, generating an alarm signal and sending the alarm signal to the control unit;
the control unit is used for generating a switching signal and sending the switching signal to the switching assembly when receiving the alarm signal generated by the processing unit, so that the switching assembly is switched to another liquid suction assembly from the liquid suction assembly which is communicated currently.
The embodiment of the invention discloses a substrate device and a substrate control system thereof. The substrate apparatus includes a chassis; a plurality of substrate containers loaded on the substrate rack; a plurality of liquid suction assemblies mounted on the base frame and corresponding to the plurality of substrate containers; a detection unit provided on the plurality of pipette units for detecting the amount of the substrate liquid stored in the plurality of substrate containers; and the switching assembly is connected with the plurality of the liquid absorbing assemblies and is used for switching from the currently communicated liquid absorbing assembly to another liquid absorbing assembly. According to the embodiment of the invention, the liquid suction operation is carried out by one liquid suction component corresponding to one substrate container, the liquid suction condition of the current liquid suction component is detected by the detection component, and when the situation that the storage amount of the substrate liquid in the substrate container corresponding to the current liquid suction component is insufficient is detected, the current liquid suction component is switched to the next liquid suction component by the switching component, so that the liquid suction operation is continuously carried out from the corresponding substrate container by the next liquid suction component, the automatic requirement of a user on the substrate device is met, and the use experience of the user is improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic view of a substrate arrangement according to an embodiment of the present invention;
FIG. 2 is a schematic view of a wicking assembly provided by an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of a wicking assembly provided by an embodiment of the present invention;
FIG. 4 is a schematic diagram of a substrate control system provided by an embodiment of the invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It will be understood that the terms "comprises" and/or "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the specification of the present invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.
Referring to fig. 1, 2 and 3, an embodiment of the invention provides a substrate device, comprising:
a bottom rack 1;
a plurality of substrate containers 2 loaded on the base rack 1;
a plurality of liquid suction units 3 mounted on the base frame 1 and corresponding to the plurality of substrate containers 2;
a detection unit 4 provided on the plurality of liquid suction units 3 for detecting the amount of the substrate liquid stored in the plurality of substrate containers 2;
and a switching assembly connected with the plurality of pipetting assemblies 3 for switching from the currently communicating pipetting assembly 3 to another pipetting assembly 3.
In this embodiment, the substrate rack 1 is a mounting carrier of the whole apparatus, the substrate containers 2 store substrate liquid, the liquid suction assemblies 3 are used for sucking the substrate liquid from the corresponding substrate containers 2, the switching assemblies are switching valves having a plurality of switching ends and a normal end, and the plurality of switching ends of the switching assemblies are respectively connected with the plurality of liquid suction assemblies 3 in an on-off manner.
The working principle of the device is as follows: the substrate liquid is absorbed in the corresponding substrate container 2 through the current liquid absorption component 3, in the process of absorbing the substrate liquid, the detection component 4 detects the storage amount of the substrate liquid in the substrate container 2 in real time, when the detection component 4 detects that the storage amount of the substrate liquid is insufficient, the switching component is disconnected with the current liquid absorption component 3 and communicated with the next liquid absorption component 3, and the substrate liquid is absorbed from the corresponding substrate container 2 through the next liquid absorption component 3, so that the normal uninterrupted operation of an instrument is maintained, and the requirement of a user on the automation of a substrate device is met.
In one embodiment, the substrate apparatus further comprises:
a plurality of lifting devices 5 arranged on the bottom rack 1;
a plurality of lifting devices 5 respectively correspond to the plurality of the imbibing assemblies 3, and each lifting device 5 is used for driving the corresponding imbibing assembly 3 to move downwards and insert into the corresponding substrate container 2 or move upwards and extend out of the corresponding substrate container 2.
In this embodiment, one lifting device 5 corresponds to one liquid suction assembly 3, and is used for driving the corresponding liquid suction assembly 3 to move upwards, extend out or move downwards and insert from the corresponding substrate container 2; when the storage amount of the substrate liquid in the substrate container 2 is insufficient, the substrate container 2 needs to be taken out and replaced, at the moment, the corresponding liquid absorption component 3 can be driven by the corresponding lifting device 5 to move upwards and extend out of the corresponding substrate container 2, the used substrate container 2 can be taken out and replaced, then the corresponding liquid absorption component 3 can be driven by the corresponding lifting device 5 to move downwards and be inserted into the replaced substrate container 2, and the replacement of the substrate container 2 can be completed.
In one embodiment, the substrate holder 1 comprises:
a base plate 11;
a plurality of mounting plates 12 arranged on the bottom plate 11, wherein each lifting device 5 and the corresponding liquid suction assembly 3 are arranged on one of the mounting plates 12;
the base plate 11 is provided with a plurality of loading positions between the mounting plates 12 for loading substrate containers.
The present embodiment is described in a preferred scenario:
three vertical plates are arranged on a bottom plate 11 side by side, wherein the vertical plates on two sides are mounting plates 12, the vertical plate in the middle is used as a partition plate, a lifting device 5 and a liquid suction assembly 3 are mounted on the mounting plates 12 on two sides, the lifting device 5 is mounted on the outer side of the mounting plates 12, the liquid suction assembly 3 is mounted on the inner side of the mounting plates 12, two loading positions 111 located between the two mounting plates 12 are arranged on the bottom plate 11, and two substrate containers 2 are loaded on the two loading positions 111; when the first liquid suction module works, if the detection component 4 detects that the substrate liquid in the substrate container 2 in the first liquid suction module is insufficient, the switching component is disconnected from the first liquid suction module, and the first liquid suction module is automatically switched to be connected with the second liquid suction module, so that the liquid suction work can be continued. Then, the user can replace the substrate container 2 by controlling the lifting device 5 in the first liquid suction module to drive the corresponding liquid suction assembly 3 to move upwards and extend out of the corresponding substrate container 2.
Further, in the process of replacing the substrate container 2, after the lifting device 5 drives the corresponding liquid suction assembly 3 to move upwards, the hatch door on the loading position 111 is opened, after a user puts the substrate container 2 containing enough substrate liquid into the loading position 111, the lifting device 5 drives the corresponding liquid suction assembly 3 to move downwards and insert into the substrate container 2, and the hatch door on the loading position 111 is closed, so that the replacement of the substrate container 2 can be completed.
In one embodiment, each wicking assembly 3 includes:
a fixed seat 31;
an output pipeline 32 which is arranged on the fixed seat 31 and is used for conveying the substrate liquid;
the sealing seat 33 is positioned below the fixed seat 31 and connected with the fixed seat 31;
a pipette 34 having one end mounted in the seal holder 33 and the other end inserted into the corresponding substrate container 2;
the adaptor 35 has one end connected to the output line 32 mounted on the fixed seat 31 and the other end connected to the pipette 34 mounted on the sealing seat 33.
In this embodiment, the fixing seat 31 and the sealing seat 33 are installation carriers of the whole pipette assembly 3, the sealing seat 33 is fixedly connected with the fixing seat 31, the output pipeline 32 is installed in the fixing seat 31, the sealing seat 33 is used for fixing the adaptor 35 and the pipette 34, and meanwhile, the inside of the sealing seat 33 is used as a channel for communicating the lower end of the adaptor 35 and the upper end of the pipette 34.
Based on this, the imbibing process of the imbibing assembly 3 is as follows: a preset amount of substrate liquid is sucked from the substrate container 2 by the pipette 34, and the substrate liquid is transferred to the adaptor 35 along the inner channel of the sealing seat 33, is transferred to the output pipeline 32 through the adaptor 35, and is then transferred out of the output pipeline 32.
In one embodiment, each wicking assembly 3 further includes:
a plurality of fixing members 36 for fixing the fixing base 31 and the sealing base 33;
a plurality of fixing members 36 pass through the fixing base 31 and are fixedly connected to the sealing base 33 downward.
In this embodiment, in order to ensure the stability of the liquid suction unit 3 during liquid suction and to prevent exposure of the substrate liquid, the stability between the fixed base 31 and the seal holder 33 needs to be ensured, and therefore, a plurality of fixing members 36 are provided to fixedly connect the fixed base 31 and the seal holder 33; preferably: three fixing members 36 are provided, the fixing members 36 may be fixing bolts, and the three fixing members 36 are passed through the lower end of the fixing base 31 from the upper end of the fixing base 31 in a triangular orientation, and are fixed to the sealing base 33 by the lower end threads of the fixing members 36, so as to fixedly connect the fixing base 31 and the sealing base 33. This embodiment is a plurality of fixed point positions of triangle position formation through a plurality of mounting 36, and the effectual stability that has improved between fixing base 31 and the seal receptacle 33 to stability when improving the imbibition.
In one embodiment, each detection assembly 4 comprises:
a sensor mounting seat 41 fixedly mounted on the fixing seat 31 corresponding to the liquid suction assembly 3;
and a bubble sensor 42 mounted on the sensor mounting base 41, wherein the bubble sensor 42 is located on the outer wall of the output pipeline 32 corresponding to the liquid suction assembly 3 and is used for detecting whether bubbles exist in the output pipeline 32.
In this embodiment, the sensor mounting seat 41 may be fixed to the fixing seat 31 by a plurality of screws, so that the bubble sensor 42 mounted on the sensor mounting seat 41 may be stably maintained, and the bubble sensor 42 may be ensured to stably detect bubbles in the substrate solution transferred through the output line 32.
During the liquid suction operation, the bubble sensor 42 detects whether there is a bubble in the output pipeline 32 of the liquid suction assembly 3 to determine the amount of the substrate liquid stored in the corresponding substrate container 2, and if the bubble in the output pipeline 32 is detected, it indicates that the amount of the substrate liquid currently sucked does not reach the preset amount, it determines that the amount of the substrate liquid stored in the corresponding substrate container 2 is insufficient.
The following describes the detection process in a specific embodiment: in the normal test, the preset amount of the substrate liquid is Xul every time, and in order to ensure that X +50ul can be sucked every time with accuracy, the bubble sensor 42 is arranged at the position of the output pipeline 32, which is closer to the substrate container 2, and the test point of the bubble sensor 42 is converted into the amount of the substrate liquid equal to Xul from the inner space of the length of the lower end of the pipette 34 (i.e., the head of the pipette 34). During the test, the bubble sensor 42 can completely detect the bubble condition of the whole substrate during each imbibition. By setting the bubble threshold value T for bubble detection, when T is greater than or equal to T in the value T returned by the bubble sensor 42 during a certain liquid suction, it is indicated that the amount of the substrate liquid sucked this time does not reach the preset amount Xul, and the substrate liquid sucked this time cannot be used for normal test, and the substrate liquid sucked this time is pushed back to the current substrate container 2 by a reverse motion.
In the embodiment, the bubble sensor 42 is arranged at the position of the output pipeline 32, the output pipeline 32 between the substrate container 2 and the bubble sensor 42 is shortened, and after bubbles are detected, the time for pushing the currently sucked substrate liquid back to the current substrate container 2 is greatly shortened, so that the time sequence arrangement of other modules is not interfered, and the speed of the whole machine is improved; the required stroke is reduced, and the method has better advantages in the aspects of model selection and cost.
In one embodiment, each lifting device 5 includes:
a drive element 51 provided on the corresponding mounting plate 12;
a transmission rod 52, one end of which is connected to the driving element 51 and the other end of which is connected to the corresponding pipetting assembly 3;
the slide rails 53 are arranged on the corresponding mounting plates 12;
and the sliding blocks 54 are slidably assembled on the sliding rails 53 and are connected with the corresponding liquid suction assemblies 3.
In this embodiment, the driving element 51 can be a motor, the transmission rod 52 can be a screw rod, one end of the transmission rod 52 is connected to a rotating shaft of the motor, the other end of the transmission rod 52 is connected to the fixed seat 31 in the pipetting assembly 3 in a threaded manner, and the fixed seat 31 is connected to the sliding block 54.
The process that elevating gear 5 drove imbibition subassembly 3 and goes up and down does: the driving element 51 drives the transmission rod 52 to rotate, the transmission rod 52 rotates to drive the fixed seat 31 and the sliding block 54 to move up and down on the sliding rail 53, namely, the whole imbibing component 3 is driven to move up and down, and the substrate container 2 is replaced in a matched manner in an automatic lifting manner, so that the user experience is effectively improved.
The embodiment of the present invention further provides a substrate control system, which includes: the device comprises a control unit, a processing unit and the substrate device, wherein the control unit is connected with the processing unit, the control unit is connected with a switching module SV1, and the processing unit is connected with a detection module 4;
the processing unit is used for receiving the detection data sent by the detection component 4, analyzing whether the detection data is in a normal threshold range, and if not, generating an alarm signal and sending the alarm signal to the control unit;
and the control unit is used for generating a switching signal and sending the switching signal to the switching assembly SV1 when receiving the alarm signal generated by the processing unit, so that the switching assembly SV1 is switched from the currently connected pipetting assembly 3 to another pipetting assembly 3.
In this embodiment, the control unit may be any controller capable of performing control operations; the processing unit can be any processor capable of performing data analysis processing, the detection component 4 can be a sensor capable of detecting the storage amount of the substrate liquid in the substrate container 2, such as a bubble sensor and a weight sensor, and the switching component SV1 can be any switching valve capable of controlling the switching of pipelines.
In the working process of the substrate device, when the detection component 4 detects the storage amount of the substrate liquid in the substrate container 2, the detected data is sent to the processing unit in real time, the processing unit receives and analyzes the data in real time, and when the processing unit analyzes that the storage amount of the substrate liquid in the substrate container 2 is insufficient, an alarm signal is sent to the control unit; when the control unit receives the alarm signal sent by the detection assembly 4, a switching signal is generated and sent to the switching assembly SV1, so that the switching assembly SV1 is switched from the currently connected pipetting assembly 3 to another pipetting assembly 3, and then the pipetting can be continued through another substrate container 2, thereby ensuring that the substrate device can continuously supply the substrate liquid and can continuously and uninterruptedly operate. The replacement requirement during online work is completely met, and the user experience is improved.
In one embodiment, the substrate control system further comprises: a first switch assembly SV2, a liquid suction driving unit Z, a second switch assembly SV3, a switching device SV4 and a plurality of substrate needles which are connected in sequence; one end of a switching assembly SV1 is connected with the output pipelines 32 of a plurality of liquid suction assemblies 3, a first switch assembly SV2 is connected with the other end of a switching assembly SV1, a liquid suction driving unit Z is respectively connected with a first switch assembly SV2 and a second switch assembly SV3, and a switching device SV4 is connected with a plurality of substrate needles;
the first switch assembly SV2 is used for controlling the on-off between the switching assembly SV1 and the suction driving unit Z;
the second switch assembly SV3 is used for controlling the on-off between the liquid suction driving unit Z and the switching device SV 4;
the suction driving unit Z is used for controlling the current suction assembly 3 to suck or push back the substrate liquid from the corresponding substrate container 2, and for injecting the substrate liquid into the current substrate needle;
the control unit is also used for controlling the imbibing driving unit Z to move reversely and push the substrate liquid which is currently imbibed by the imbibing component 3 back to the current substrate container 2 after receiving the alarm signal generated by the processing unit and before generating a switching signal.
In this embodiment, the first switch module SV2 and the second switch module SV3 may be any switch valves capable of controlling the on/off of the lines, the pipetting driving unit Z may be a substrate injector, the switching device SV4 may be any switching valve capable of controlling the switching of the lines, and the substrate needle is used for pouring out the substrate liquid.
The following is a specific scenario: in a certain detection, 200ul of reaction substrate liquid needs to be filled, the liquid suction driving unit Z has a capacity of 500ul, the liquid suction assembly 3 is provided with two liquid suction assemblies which respectively correspond to a substrate container F1 and a substrate container F2(F1 and F2 are the substrate containers 2 in the substrate device), the detection assembly 4 can comprise a detection unit Q1 and a detection unit Q2(Q1 and Q2 are the bubble sensors 42 in the substrate device) which are arranged in the two liquid suction assemblies 3, the detection assembly 4 can be one detection unit or can realize the bubble detection of a plurality of liquid suction assemblies 3 when the detection assembly 4 is arranged at the output end positions of the two liquid suction assemblies 3, and the substrate needles are provided with two, namely the substrate needle DD1 and the substrate needle DD 2.
The present scenario will be further explained by taking in the substrate liquid in the substrate container F1 and injecting the liquid into the substrate needle DD 1:
the process of one-time imbibition: the first switch module SV2 is turned on, and 250ul of substrate liquid is sucked from the substrate container F1 by the present pipetting module 3 after the pipetting drive unit Z is reset; the length of the interval from the pipette 34 of the pipette assembly 3 to the test site of the detecting unit Q1 is currently converted into 200ul (+ -10 ul) of liquid amount, since the diameter of the pipeline cannot be controlled to be equal in terms of manufacturing, the whole 250ul of the substrate liquid is sucked and detected by the detecting unit Q1; when the processing unit does not send out an alarm signal, the first switch assembly SV2 is closed, the second switch assembly SV3 is opened, the liquid suction driving unit Z is reset after liquid injection is 200ul, the second switch assembly SV3 is closed, and the process is ended.
When the detection unit Q1 detects bubbles and the processing unit sends an alarm signal, the liquid suction is still continuously performed, but the liquid suction driving unit Z is controlled to move reversely after the liquid suction is finished, the sucked substrate liquid is pushed back to the substrate container F1, and meanwhile, the pushed substrate pipeline is still filled with the substrate liquid, so that the whole pipeline does not need to be filled when the next replacement is carried out, the maintenance burden of users and service personnel is reduced, and the cost of filling the substrate liquid is also reduced; the switch assembly SV1 is then controlled by the control system to disconnect from the current pipetting assembly 3 and switch assembly SV1 is connected to the other pipetting assembly 3, i.e. when the other pipetting assembly 3 and substrate container F2 are activated.
The detection principle of the detection unit Q1 in this specific scenario is as follows: the detection unit Q1 detects the bubble value of the substrate liquid in the output pipeline 32 when the substrate liquid is sucked by the front liquid suction assembly 3 and sends the bubble value of the substrate liquid to the processing unit, the processing unit compares the received bubble value of the substrate liquid with a preset bubble threshold value, and if the bubble value of the substrate liquid exceeds the bubble threshold value, an alarm signal is generated and sent to the control system.
While the invention has been described with reference to specific embodiments, the invention is not limited thereto, and various equivalent modifications and substitutions can be easily made by those skilled in the art within the technical scope of the invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. A substrate device, comprising:
a bottom shelf;
a plurality of substrate containers loaded on the chassis;
a plurality of pipetting assemblies mounted on said base frame and corresponding to said plurality of substrate containers;
a detection component arranged on the plurality of liquid suction components and used for detecting the substrate liquid storage amount in the plurality of substrate containers;
a switching assembly connected with the plurality of pipetting assemblies for switching from a currently communicating pipetting assembly to another pipetting assembly.
2. The substrate apparatus according to claim 1, wherein: the substrate apparatus further comprises:
the lifting devices are arranged on the bottom rack;
the plurality of lifting devices respectively correspond to the plurality of imbibing assemblies, and each lifting device is used for driving the corresponding imbibing assembly to move downwards and be inserted into the corresponding substrate container or move upwards and extend out of the corresponding substrate container.
3. The substrate apparatus according to claim 2, wherein: the substrate holder comprises:
a base plate;
the lifting devices and the corresponding liquid suction assemblies are arranged on one of the mounting plates;
the base plate is provided with a plurality of loading positions located between the plurality of mounting plates, and the loading positions are used for loading the substrate containers.
4. The substrate apparatus according to claim 1, wherein: each of said wicking assemblies comprising:
a fixed seat;
the output pipeline is arranged on the fixed seat and used for conveying the substrate liquid;
the sealing seat is positioned below the fixed seat and connected with the fixed seat;
one end of the pipette is arranged in the sealing seat, and the other end of the pipette is inserted into the corresponding substrate container;
one end of the adaptor is connected with an output pipeline arranged on the fixing seat, and the other end of the adaptor is connected with a pipette arranged on the sealing seat.
5. The substrate apparatus according to claim 4 wherein each of said wicking assemblies further comprises:
the fixing parts are used for fixing the fixing seat and the sealing seat;
the fixing pieces penetrate through the fixing seat and are fixedly connected to the sealing seat downwards.
6. The substrate apparatus according to claim 4, wherein: each of the detection assemblies includes:
the sensor mounting seat is fixedly arranged on the fixing seat corresponding to the liquid suction assembly;
and the bubble sensor is arranged on the sensor mounting seat, is positioned on the outer wall of the output pipeline corresponding to the liquid suction assembly and is used for detecting whether bubbles exist in the output pipeline or not.
7. A substrate arrangement according to claim 3, wherein: each of the lifting devices comprises:
the driving elements are arranged on the corresponding mounting plates;
one end of the transmission rod is connected with the driving element, and the other end of the transmission rod is connected with the corresponding liquid suction assembly;
the sliding rails are arranged on the corresponding mounting plates;
and the sliding block is assembled on the sliding rail in a sliding manner and is connected with the corresponding liquid suction assembly.
8. A substrate control system, comprising: a control unit, a processing unit, a substrate arrangement according to any of claims 1-7, the control unit being connected to the processing unit, the control unit being connected to the switching assembly, the processing unit being connected to the detection assembly;
the processing unit is used for receiving the detection data sent by the detection assembly, analyzing whether the detection data is in a normal threshold range, and if not, generating an alarm signal and sending the alarm signal to the control unit;
the control unit is used for generating a switching signal and sending the switching signal to the switching assembly when receiving the alarm signal generated by the processing unit, so that the switching assembly is switched to another liquid suction assembly from the liquid suction assembly which is communicated currently.
9. The substrate control system of claim 8, further comprising: the first switch component, the imbibition driving unit, the second switch component, the switching device and the plurality of substrate needles are connected in sequence; one end of the switching assembly is connected with the output pipelines of the plurality of imbibing assemblies, the first switch assembly is connected to the other end of the switching assembly, the imbibing driving unit is respectively connected with the first switch assembly and the second switch assembly, and the switching device is connected with the plurality of substrate needles;
the first switch assembly is used for controlling the on-off between the switching assembly and the liquid suction driving unit;
the second switch assembly is used for controlling the on-off between the liquid suction driving unit and the switching device;
the imbibition driving unit is used for controlling the current imbibition assembly to aspirate or push back the substrate liquid from the corresponding substrate container and injecting the substrate liquid into the current substrate needle;
the control unit is also used for controlling the imbibing driving unit to move reversely and pushing the substrate liquid which is currently imbibed by the imbibing component back to the current substrate container after receiving the alarm signal generated by the processing unit and before generating a switching signal.
10. The substrate control system of claim 8, wherein the detection assembly comprises a detection unit for detecting a plurality of pipetting assemblies; the detection unit is used for detecting the substrate liquid bubble value in an output pipeline of the liquid suction assembly when the liquid suction assembly sucks the substrate liquid and sending the substrate liquid bubble value to the processing unit.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111186006.9A CN113934236A (en) | 2021-10-12 | 2021-10-12 | Substrate device and substrate control system thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111186006.9A CN113934236A (en) | 2021-10-12 | 2021-10-12 | Substrate device and substrate control system thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113934236A true CN113934236A (en) | 2022-01-14 |
Family
ID=79278345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111186006.9A Pending CN113934236A (en) | 2021-10-12 | 2021-10-12 | Substrate device and substrate control system thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113934236A (en) |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2531421Y (en) * | 2002-02-01 | 2003-01-15 | 北京康德威医疗设备有限公司 | Automatic liquid level control device for central liquid supply system |
CN107462734A (en) * | 2017-08-08 | 2017-12-12 | 华东医药(杭州)基因科技有限公司 | A kind of sample adding device and control method applied to liquid biological reaction system |
CN110082543A (en) * | 2018-01-25 | 2019-08-02 | 深圳市新产业生物医学工程股份有限公司 | Automatic analysing apparatus and drawing liquid monitoring method |
CN211800901U (en) * | 2019-12-31 | 2020-10-30 | 苏州长光华医生物医学工程有限公司 | Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device |
CN112326951A (en) * | 2020-11-03 | 2021-02-05 | 苏州长光华医生物医学工程有限公司 | Full-automatic substrate switching device |
CN112585477A (en) * | 2018-09-26 | 2021-03-30 | 株式会社日立高新技术 | Automatic analysis system |
CN112763482A (en) * | 2021-02-03 | 2021-05-07 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
CN113082971A (en) * | 2021-03-31 | 2021-07-09 | 重庆中元汇吉生物技术有限公司 | Filter element assembly, substrate reagent bin assembly, substrate gas-liquid path system and substrate suction and discharge method |
CN214096728U (en) * | 2020-10-30 | 2021-08-31 | 重庆中元汇吉生物技术有限公司 | Substrate collection system |
-
2021
- 2021-10-12 CN CN202111186006.9A patent/CN113934236A/en active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2531421Y (en) * | 2002-02-01 | 2003-01-15 | 北京康德威医疗设备有限公司 | Automatic liquid level control device for central liquid supply system |
CN107462734A (en) * | 2017-08-08 | 2017-12-12 | 华东医药(杭州)基因科技有限公司 | A kind of sample adding device and control method applied to liquid biological reaction system |
CN110082543A (en) * | 2018-01-25 | 2019-08-02 | 深圳市新产业生物医学工程股份有限公司 | Automatic analysing apparatus and drawing liquid monitoring method |
CN112585477A (en) * | 2018-09-26 | 2021-03-30 | 株式会社日立高新技术 | Automatic analysis system |
CN211800901U (en) * | 2019-12-31 | 2020-10-30 | 苏州长光华医生物医学工程有限公司 | Chemiluminescence analyzer, substrate bottle assembly thereof and substrate liquid extraction device |
CN214096728U (en) * | 2020-10-30 | 2021-08-31 | 重庆中元汇吉生物技术有限公司 | Substrate collection system |
CN112326951A (en) * | 2020-11-03 | 2021-02-05 | 苏州长光华医生物医学工程有限公司 | Full-automatic substrate switching device |
CN112763482A (en) * | 2021-02-03 | 2021-05-07 | 苏州长光华医生物医学工程有限公司 | Substrate liquid supply device |
CN113082971A (en) * | 2021-03-31 | 2021-07-09 | 重庆中元汇吉生物技术有限公司 | Filter element assembly, substrate reagent bin assembly, substrate gas-liquid path system and substrate suction and discharge method |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3671218A1 (en) | Blood analyzer and control method therefor | |
US4861553A (en) | Automatic sampling system | |
CN107063830B (en) | Vaginal secretion sample pretreatment device | |
CN107656085B (en) | Blood detector | |
US9791465B2 (en) | Automatic analyzer | |
CN109682981A (en) | Sample transporting apparatus, sample analysis system and its control method | |
CN108373966B (en) | Culture medium box operating device and operating method | |
CN112239076A (en) | Pushing device | |
CN110398591A (en) | A kind of sample analysis system and a kind of sample analysis system control method | |
CN111374889A (en) | Dispensing device, dispensing robot and dispensing method | |
CN104355033A (en) | Automatic multilayer storage box for perforated plates for biological detection | |
CN113934236A (en) | Substrate device and substrate control system thereof | |
US4476734A (en) | Wet needle sampler for use with a gas chromatograph | |
CN115839872B (en) | Full-automatic liquid-based cell slice-making dyeing machine | |
CN210632135U (en) | Batch liquid adding device for laboratory | |
JP4927444B2 (en) | Liquid preparation equipment | |
JP5629277B2 (en) | Liquid preparation equipment | |
JP2007309890A (en) | Dispenser | |
CN111257546B (en) | POCT detection system | |
CN108780108A (en) | Automatic analysing apparatus | |
CN115178136A (en) | Flexible processing equipment for precise electronic components | |
EP0391746B1 (en) | Apparatus for the separate injection of reagents | |
JP5039456B2 (en) | Liquid chromatograph analyzer | |
CN207281082U (en) | The pallet and its support system of full-automatic Western blotting instrument | |
JPH06317599A (en) | Dispenser |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |