CN110082543A - Automatic analysing apparatus and drawing liquid monitoring method - Google Patents
Automatic analysing apparatus and drawing liquid monitoring method Download PDFInfo
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- CN110082543A CN110082543A CN201810074886.2A CN201810074886A CN110082543A CN 110082543 A CN110082543 A CN 110082543A CN 201810074886 A CN201810074886 A CN 201810074886A CN 110082543 A CN110082543 A CN 110082543A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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Abstract
The present invention relates to a kind of automatic analysing apparatus and drawing liquid monitoring method, the automatic analysing apparatus includes: drawing liquid module；Turntable, equipped with multiple receiving positions for accommodating container, each receiving position is for accommodating a container；Bubble detecting sensor, set on turntable top, close to drawing liquid module pipeline one end liquid sucting port position, for whether thering is bubble to detect in the pipeline to drawing liquid module；Control module is electrically connected bubble detecting sensor, for controlling drawing liquid module to container progress drawing liquid and starting timing, if liquid arrival is still not detected in bubble detecting sensor after drawing liquid starts the first duration, reports an error；Since control module be also used to still be not detected when bubble reaches after the second duration detecting that liquid reaches and report an error.The present invention is monitored drawing liquid by the way that bubble detecting sensor is arranged above container, and space is rationally utilized, will not mutually tie up installation space with the other component of automatic analysing apparatus.
Description
Technical field
It is special the present invention relates to being tested or the technical field of analysis of material by means of the chemically or physically property for measuring material
It is not to be related to a kind of automatic analysing apparatus, further relates to a kind of drawing liquid monitoring method.
Background technique
Automatic analyzer, such as Full-automatic chemiluminescence diagnostic instrments react " magnetic bead-reagent-sample " after incubation
Object is cleaned multiple times, and dissociant is removed.Due to magnetic bead, the serum, albumen in " magnetic bead-reagent-sample " reactant
Equal ingredients, are very easy to cause liquid pumping needle and pipeline blockage, so that the measurement of experimental result is influenced, so how in cleaning
It is significant that drawing liquid process carries out effective monitoring.
A kind of automatic analyzer needs to install below turntable the components such as magnet, can reflection light, passed according to installation light
The method of the detection modules such as sensor carries out drawing liquid monitoring, then can generate large error.
Summary of the invention
Based on this, it is necessary to provide a kind of automatic analysing apparatus and drawing liquid monitoring side that can carry out effective monitoring to drawing liquid
Method.
A kind of automatic analysing apparatus, including drawing liquid module, further includes: turntable, the receiving equipped with multiple holding said containers
Position, each receiving position is for accommodating a container；Bubble detecting sensor, set on the top of the turntable, close to drawing liquid
The position of the liquid sucting port of pipeline one end of module, for whether thering is bubble to detect in the pipeline to the drawing liquid module；Control
Molding block is electrically connected the bubble detecting sensor, carries out drawing liquid to container and based on starting by controlling the drawing liquid module
When, if liquid arrival is still not detected in the bubble detecting sensor after drawing liquid starts the first duration, report an error；The control mould
Since block be also used to still be not detected when bubble reaches after the second duration detecting that liquid reaches and report an error.
The control module carries out drawing liquid to container for controlling drawing liquid module in one of the embodiments, and record is taken out
T0 at the time of liquid starts；And detect whether the pipeline has liquid arrival by the bubble detecting sensor, it is recorded in described
T1 at the time of detecting liquid in pipeline；If liquid is still not detected in the bubble detecting sensor after moment T0 starts the first duration
Body reaches, then the control module reports an error.
The control module is also used to record bubble detecting sensor and detects after moment T1 in one of the embodiments,
T2 at the time of having bubble arrival to the pipeline；If the bubble detecting sensor does not detect yet after moment T1 starts the second duration
It is reached to bubble, then the control module reports an error.
It in one of the embodiments, further include the memory for being stored with the drawing liquid speed of the drawing liquid module；The control
Molding block, which is also used to subtracting moment T2 into moment T1, obtains this drawing liquid duration, calculates this drawing liquid in conjunction with the drawing liquid speed
Amount.
It in one of the embodiments, further include liquid detection sensor, for being carried out in container with the presence or absence of liquid
Detection.
The liquid detection sensor is set to the receiving position lower section or the receiving position side in one of the embodiments,
Face.
It in one of the embodiments, further include the fixation device above the turntable, the drawing liquid module and institute
Bubble detecting sensor is stated to be installed on the fixed device.
The drawing liquid module includes drawing liquid pump, liquid pumping needle and the connection drawing liquid pump and institute in one of the embodiments,
State the pipeline of liquid pumping needle.
A kind of drawing liquid monitoring method, for carrying out drawing liquid monitoring to automatic analysing apparatus, the automatic analysing apparatus includes
Drawing liquid module, the automatic analysing apparatus further include: turntable, the receiving position equipped with multiple holding said containers, each receiving position
For accommodating a container；Bubble detecting sensor, the top set on the turntable, pipeline one end close to drawing liquid module
Liquid sucting port position, for whether thering is bubble to detect in the pipeline to the drawing liquid module；The described method includes: control
The drawing liquid module carries out drawing liquid to container and starts timing, if drawing liquid start the first duration after the bubble detecting sensor still
Liquid arrival is not detected, then reports an error；If since detecting that liquid reaches after the second duration, the bubble detecting sensor still
Bubble arrival is not detected, then reports an error.
T0 is recorded as at the time of being further comprised the steps of: in one of the embodiments, by the beginning timing；By the detection
T1 is recorded as at the time of arrival to liquid.
Further comprise the steps of: in one of the embodiments, by it is described detect bubble reach at the time of be recorded as T2.
The drawing liquid speed for obtaining the drawing liquid module is further comprised the steps of: in one of the embodiments,；Moment T2 is subtracted
Moment T1 obtains this drawing liquid duration, calculates this drawing liquid amount in conjunction with the drawing liquid speed.
In one of the embodiments, the control drawing liquid module drawing liquid is carried out to container and the step of start timing it
Before, further include the steps that detecting in the container with the presence or absence of liquid, if so then execute the control drawing liquid module to container into
Row drawing liquid and the step of start timing.
The step of drawing liquid speed for obtaining the drawing liquid module includes: that offer fills in one of the embodiments,
The container of liquid, and the volume of the liquid in containers is L；It controls the drawing liquid module and drawing liquid is carried out to the container,
Ta at the time of record drawing liquid starts；Whether there is liquid to arrive by the pipeline that the bubble detecting sensor detects the drawing liquid module
It reaches, and is recorded in the pipeline Tb at the time of detecting liquid；If liquid is still not detected after starting third duration in moment Ta
It reaches, then reports an error；It detects whether the pipeline has bubble arrival by the bubble detecting sensor after the moment Tb, and remembers
Tc at the time of record detects bubble in the pipeline；If bubble arrival is still not detected after starting the 4th duration in moment Tb,
It reports an error；The drawing liquid speed is calculated, the drawing liquid speed, which is equal in volume/pipeline of the liquid in containers, detects gas
Difference at the time of liquid is detected at the time of bubble and in the pipeline.
The automatic analysing apparatus further includes cleaning solution output module in one of the embodiments, and the offer fills
The step of container of liquid is the cleaning solution that the cleaning solution output module injects that volume is L into empty container.
Above-mentioned automatic analysing apparatus and drawing liquid monitoring method, by the way that bubble detecting sensor is arranged above container to drawing liquid
It is monitored, space is rationally utilized, will not mutually tie up installation space with the other component of automatic analysing apparatus.
Detailed description of the invention
Fig. 1 is the local structural graph of automatic analysing apparatus in an embodiment；
Fig. 2 is the flow chart of drawing liquid monitoring method in an embodiment；
Fig. 3 is the flow chart of drawing liquid monitoring method in another embodiment；
Fig. 4 is the flow chart that the method for drawing liquid speed of drawing liquid module is tested in an embodiment.
Specific embodiment
To facilitate the understanding of the present invention, a more comprehensive description of the invention is given in the following sections with reference to the relevant attached drawings.In attached drawing
Give preferred embodiment of the invention.But the invention can be realized in many different forms, however it is not limited to this paper institute
The embodiment of description.On the contrary, purpose of providing these embodiments is make it is more thorough and comprehensive to the disclosure.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more phases
Any and all combinations of the listed item of pass.
It should be understood that although each step in flow chart of the invention is successively shown according to the instruction of arrow,
It is these steps is not that the inevitable sequence according to arrow instruction successively executes.Unless expressly stating otherwise herein, these steps
There is no stringent sequences to limit for rapid execution, can execute in the other order.Moreover, in flow chart of the invention extremely
Few a part of step may include that perhaps these sub-steps of multiple stages or stage are not necessarily same to multiple sub-steps
Moment executes completion, but can execute at different times, and execution sequence is also not necessarily and successively carries out, but can be with
At least part of the sub-step or stage of other steps or other steps executes in turn or alternately.
Fig. 1 is the local structural graph of automatic analysing apparatus in an embodiment, which automatically analyzes dress primarily to showing
It sets and monitors related component with drawing liquid, therefore the section components of automatic analysing apparatus are omitted in figure.
Automatic analysing apparatus includes drawing liquid module (Fig. 1 is not indicated), turntable 10, bubble detecting sensor 30 and control module
(not showing in Fig. 1).
Turntable 10 is equipped with multiple receiving positions for accommodating container 12, and each receiving position is for accommodating a container 12.
Bubble detecting sensor 30 is set to the top of turntable 10, pipeline 22 (i.e. drawing liquid pipeline) one end close to drawing liquid module
Liquid sucting port 224 position, for whether thering is bubble to detect in pipeline 22.It in one embodiment, can be according to need
Multiple bubble detecting sensors are correspondingly set on a plurality of pipeline.
Control module and bubble detecting sensor 30 are electrically connected, and carry out drawing liquid simultaneously to container 12 for controlling drawing liquid module
Timing reports an error if liquid arrival is still not detected in bubble detecting sensor 30 after drawing liquid starts the first duration.Control module is also
When progress is reached for bubble to be still not detected after the second duration since detecting that liquid reaches in bubble detecting sensor 30
It reports an error.Wherein, the first duration can be rule of thumb arranged, that is, an experience duration is arranged, is characterized in drawing liquid module and starts drawing liquid
The duration for not drawing up liquid yet after a period of time, being then judged as drawing liquid exception.Second duration can be according to the drawing liquid of drawing liquid module
Speed and the setting of drawing liquid amount, that is, be arranged an experience duration, yet will not be characterized in after drawing liquid module starts drawing liquid for a period of time
Container evacuation, the experience duration for being then judged as drawing liquid exception.It should be understood that the second duration can be greater than the first duration significantly.
Above-mentioned automatic analysing apparatus is monitored drawing liquid by the way that bubble detecting sensor 30 is arranged above container, closes
Space is utilized in reason, will not mutually tie up installation space with the other component of automatic analysing apparatus.
In the embodiment shown in fig. 1, automatic analysing apparatus further includes liquid detection sensor 40, for turning to by turntable
It is detected in the container 12 at 40 position of liquid detection sensor with the presence or absence of liquid.In the embodiment shown in fig. 1,
The entrance that liquid detection sensor 40 is set to turntable 10 (being cleaning disk in the present embodiment) accommodates at position.The turntable 10 is provided only with one
A entrance accommodates position.Due to being mounted with magnet below each liquid pumping needle, liquid detection sensor 40 can be held set on entrance
It receives at position.It can be specifically set to container side, compared to container bottom is set to, the risk splashed by the solution in container can be reduced.
In one embodiment, liquid detection sensor 40, which is set to, accommodates below position or accommodates position side, that is, is located at container
12 bottom or side.
In one embodiment, automatic analysing apparatus includes 4 bubble detecting sensors 30 and a liquid detecting sensing
Device 40.
In one embodiment, automatic analysing apparatus further includes memory, and the drawing liquid of drawing liquid module is stored in memory
Speed.Control module is for executing the following steps:
It controls drawing liquid module and drawing liquid, T0 at the time of record drawing liquid starts is carried out to container 12.
Whether there is liquid arrival by 30 signal piping 22 of bubble detecting sensor, is recorded in pipeline 22 and detects liquid
At the time of T1.If liquid arrival, control module is still not detected in bubble detecting sensor 30 after moment T0 starts the first duration
It reports an error.
Record bubble detecting sensor 30 detects T2 at the time of pipeline 22 has bubble arrival after moment T1.If moment T1
Bubble arrival is still not detected in bubble detecting sensor 30 after starting the second duration, then control module reports an error.
Moment T2 is subtracted into moment T1 and obtains this drawing liquid duration, calculates this in conjunction with the drawing liquid speed that memory stores
Drawing liquid amount.Can judge the stopping state of pipeline to a certain extent by drawing liquid amount and drawing liquid speed, if drawing liquid amount or
Drawing liquid speed very little, it is likely that be that pipeline is blocked or aging.
In one embodiment, automatic analysing apparatus further includes cleaning solution output module.Cleaning solution output module be used for
Cleaning solution is injected in container 12, to start the cleaning processing to container 12.
In one embodiment, control module is also used to the control when container 12 is by near liquid detection sensor 40
It whether there is liquid in 40 detection container 12 of liquid detection sensor, liquid control drawing liquid module just carries out container 12 if it exists
Drawing liquid.
In the embodiment shown in fig. 1, automatic analysing apparatus further includes the fixation device 50 set on 10 top of turntable.Drawing liquid
Module and bubble detecting sensor 30 are installed on fixed device 50.
In the embodiment shown in fig. 1, drawing liquid module includes drawing liquid pump (Fig. 1 does not show), liquid pumping needle 24 and connection drawing liquid pump
With the pipeline 22 of liquid pumping needle 24.
In one embodiment, control module is also used to execute the following steps:
It controls cleaning solution output module and injects the cleaning solution that volume is L to empty container 12.
It controls drawing liquid module and drawing liquid, Ta at the time of record drawing liquid starts is carried out to container 12.
Whether there is liquid arrival by 30 signal piping 22 of bubble detecting sensor, is recorded in pipeline 22 and detects liquid
At the time of Tb.If liquid arrival, control module is still not detected in bubble detecting sensor 30 after moment Ta starts third duration
It reports an error.
Record bubble detecting sensor 30 detects Tc at the time of pipeline 22 has bubble arrival after moment Tb.If moment Tb
Bubble arrival is still not detected in bubble detecting sensor 30 after starting the 4th duration, then control module reports an error.
It calculates drawing liquid speed △ L=L/ (Tc-Tb), and by drawing liquid speed △ L storage into memory.
In one embodiment, it is the clear of L that control module, which controls cleaning solution output module to inject volume to empty container 12,
Before washing lotion, it is also used to control drawing liquid module emptying pipeline 22.
In one embodiment, it is the clear of L that control module, which controls cleaning solution output module to inject volume to empty container 12,
After washing lotion, it is also used to control in 40 detection container of liquid detection sensor with the presence or absence of liquid, to judge whether fluid injection succeeds,
Just continue to control drawing liquid module only under fluid injection success status to the progress drawing liquid of container 12.
The present invention correspondingly provides a kind of drawing liquid monitoring method, should be certainly for carrying out drawing liquid monitoring to automatic analysing apparatus
Dynamic analytical equipment can be automatic analysing apparatus described in any of the above embodiment.The monitoring method of the cleaning container system of Fig. 1
Include the following steps:
Fig. 2 is the flow chart of drawing liquid monitoring method in an embodiment, including the following steps:
S10, control drawing liquid module carry out drawing liquid to container and start timing.
Whether S20 has liquid arrival by the pipeline that bubble detecting sensor detects drawing liquid module.
If liquid arrival is still not detected after starting the first duration in drawing liquid, reports an error, otherwise enter step S30.
Whether S30 has bubble arrival by the pipeline that bubble detecting sensor detects drawing liquid module.
If bubble is not detected after the second duration, still since bubble detecting sensor detects that liquid reaches to reach,
It reports an error.
In one embodiment, container is reaction cup.It should be understood that in other embodiments, container may be examination
Other containers such as pipe.
Fig. 3 is the flow chart of drawing liquid monitoring method in another embodiment, is included the following steps:
S110 obtains the drawing liquid speed of drawing liquid module.
There is the drawing liquid speed of mark drawing liquid module for producer, can be directly used.It can also be known using this field
The method of test drawing liquid module drawing liquid speed tested.
Referring to fig. 4, inventor provides a kind of embodiment of drawing liquid speed for testing drawing liquid module, that is, passes through cleaning container system
Drawing liquid speed is calculated in the initialization of system, specifically comprises the following steps:
S111 provides the container for filling liquid, and the volume of liquid in containers is L.
It in the present embodiment, is to inject the cleaning solution that volume is L into empty container by cleaning solution output module.At one
In embodiment, cleaning solution output module may include the syringe pump of a calibrated shot, and L is that the syringe pump quantitatively projects once
Volume.Cleaning solution output module further includes injection needle and the pipeline for connecting syringe pump and injection needle.In one embodiment, L
It is 400 microlitres.
S112, drawing liquid module carry out drawing liquid, Ta at the time of record drawing liquid starts to container.
In the present embodiment, drawing liquid module includes drawing liquid pump, liquid pumping needle and the drawing liquid pipeline for connecting drawing liquid pump and liquid pumping needle.
In one embodiment, drawing liquid pump can be peristaltic pump.In liquid pumping needle intercalation reaction cup, drawing liquid pump starts drawing liquid and records current
Moment Ta.
S113 judges that Ta starts whether to detect that the pipeline of drawing liquid module has liquid arrival in third duration, if so, into
Enter step S114, otherwise reports an error.
Whether the pipeline for detecting drawing liquid module since moment Ta has liquid arrival, and is delayed and waits third duration, if
Pipeline is not detected in third duration always liquid arrival, then reports an error, and informs that operator's drawing liquid is abnormal.Third duration can be with
Rule of thumb be arranged, that is, be arranged an experience duration, be characterized in after drawing liquid module starts drawing liquid for a period of time do not draw up yet liquid,
Then it is judged as the duration of drawing liquid exception.In one embodiment, third duration can be 3s.
S114 is recorded in pipeline Tb at the time of having detected liquid.
After detecting that pipeline has liquid arrival, drawing liquid module continues drawing liquid.
S115 judges that Tb starts whether detect that the pipeline of drawing liquid module has bubble arrival in the 4th duration, if so, into
Enter step S116, otherwise reports an error.
Whether the pipeline for detecting drawing liquid module since moment Tb has bubble arrival, and is delayed and waits the 4th duration, if
Pipeline is not detected in 4th duration always bubble arrival, then reports an error, and informs that operator's drawing liquid is abnormal.4th duration can be with
It is arranged according to the speed of drawing liquid and drawing liquid amount, that is, an experience duration is set, when is characterized in drawing liquid module and starting one section of drawing liquid
Between after container evacuated yet, be not judged as the experience duration of drawing liquid exception then.It should be understood that the 4th duration can be greater than significantly
Third duration.
S116 is recorded in pipeline Tc at the time of detecting bubble.
After detecting that pipeline has bubble arrival, drawing liquid module can stop drawing liquid.
S117 calculates drawing liquid speed=L/ (Tc-Tb).
Cleaning solution volume in container is L, and the drawing liquid time is Tc-Tb, then the unit time drawing liquid amount △ L=of drawing liquid module
L/(Tc-Tb)。
The initialization procedure that cleaning container system is completed by above step, obtains drawing liquid speed.Cleaning container system later
System can start to work normally.Specifically, drawing liquid monitoring method further includes following steps:
S120, drawing liquid module carry out drawing liquid, T0 at the time of record drawing liquid starts to container.
In the present embodiment, container to be cleaned enters cleaning positions, and in liquid pumping needle intercalation reaction cup, drawing liquid pump starts to take out
Liquid simultaneously records current time T0.
S130 judges that T0 starts whether to detect that the pipeline of drawing liquid module has liquid arrival in the first duration, if so, into
Enter step S140, otherwise reports an error.
Whether the pipeline for detecting drawing liquid module since moment T0 has liquid arrival, and is delayed and waits the first duration, if
Pipeline is not detected in first duration always liquid arrival, then reports an error, and informs that operator's drawing liquid is abnormal.First duration can be with
Rule of thumb be arranged, that is, be arranged an experience duration, be characterized in after drawing liquid module starts drawing liquid for a period of time do not draw up yet liquid,
Then it is judged as the duration of drawing liquid exception.In one embodiment, the first duration and third duration are equal.
S140 is recorded in pipeline T1 at the time of detecting liquid.
After detecting that pipeline has liquid arrival, drawing liquid module continues drawing liquid.
S150 judges that T1 starts whether to detect that the pipeline of drawing liquid module has bubble arrival in the second duration, if so, into
Enter step S160, otherwise reports an error.
Whether the pipeline for detecting drawing liquid module since moment Tb has bubble arrival, and is delayed and waits the second duration, if
Pipeline is not detected in second duration always bubble arrival, then reports an error, and informs that operator's drawing liquid is abnormal.Second duration can be with
It is arranged according to the speed of drawing liquid and drawing liquid amount, that is, an experience duration is set, when is characterized in drawing liquid module and starting one section of drawing liquid
Between after container evacuated yet, be not judged as the experience duration of drawing liquid exception then.It should be understood that the second duration can be greater than significantly
First duration.In one embodiment, the second duration and the 4th duration are equal.
S160 is recorded in pipeline T2 at the time of detecting bubble.
After detecting that pipeline has bubble arrival, drawing liquid module can stop drawing liquid.
S170, T2 subtract T1 and obtain this drawing liquid duration, calculate this drawing liquid amount in conjunction with drawing liquid speed.
In the present embodiment, the drawing liquid amount L1=△ L* (T2-T1) of this cleaning.
The monitoring method of said vesse cleaning system, it is whether normal in two nodal test drawing liquids of step S130 and S150,
And the drawing liquid amount of cleaning can be calculated by step S170, realize the effective monitoring to drawing liquid in cleaning process.Pass through drawing liquid
Amount and drawing liquid speed can judge the stopping state of pipeline to a certain extent, if drawing liquid amount or drawing liquid speed very little,
Pipeline is likely to be to be blocked or aging.
It should be understood that executing a step S120 to S170, completion is a drawing liquid.In one embodiment, it walks
After the completion of rapid S170, step S180 can also be performed: cleaning solution being added into container by cleaning solution output module, is then returned
Step S120 and sequence are executed to S170, then complete the drawing liquid amount for once cleaning and having recorded the secondary cleaning again.Iterative cycles
Step S180-S120-S130-S140-S150-S160--S170 is executed, the drawing liquid amount being cleaned multiple times is recorded respectively, thus to appearance
Device cleaning system carries out continuing monitoring, can effectively avoid pipeline blockage, guarantees being normally carried out for cleaning process.
In one embodiment, further include the steps that before step S120 in detection container with the presence or absence of liquid.That is container
In cleaning system course of normal operation, it whether there is liquid in first detection container, liquid just executes step S120 if it exists, carries out
Drawing liquid.
Likewise, in the initialization procedure of cleaning container system shown in Fig. 2, by cleaning solution output module to empty container
After the cleaning solution that middle injection volume is L, liquid can also be whether there is in first detection container, liquid just executes step if it exists
S112 carries out drawing liquid.
It in one embodiment, further include the emptying of drawing liquid module before step S112 drawing liquid module carries out drawing liquid to container
The step of drawing liquid pipeline.In one embodiment, can be by hanging (not protruding into container) by liquid pumping needle, then drawing liquid pumping
The mode of the 5th duration of liquid empties drawing liquid pipeline.Wherein the 5th when it is a length of in the case where liquid pumping needle does not suck liquid, drawing liquid pump
Empty pump can be by the empirical value of drawing liquid pipeline evacuation.In one embodiment, the 5th duration is equal to the first duration or third duration.
In one embodiment, further include the steps that emptying drawing liquid pipeline after step S116.It should be understood that drawing liquid is complete
Liquid pumping needle is lifted after, then again drawing liquid for a period of time,
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with
It controls relevant hardware by computer program to complete, which can be stored in a computer-readable storage medium
In, the program is when being executed, it may include such as the process of each embodiment of above-mentioned each method.Wherein, storage medium above-mentioned can be
The non-volatile memory mediums such as magnetic disk, CD, read-only memory (Read-Only Memory, ROM) or random storage note
Recall body (Random Access Memory, RAM) etc..
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (15)
1. a kind of automatic analysing apparatus, including drawing liquid module, which is characterized in that further include:
Turntable, the receiving position equipped with multiple holding said containers, each receiving position is for accommodating a container；
Bubble detecting sensor, set on the turntable top, close to drawing liquid module pipeline one end liquid sucting port position, use
Whether there is bubble to detect in the pipeline to the drawing liquid module；
Control module is electrically connected the bubble detecting sensor, carries out drawing liquid simultaneously to container for controlling the drawing liquid module
Start timing, if liquid arrival is still not detected in the bubble detecting sensor after drawing liquid starts the first duration, reports an error；It is described
Since control module be also used to still be not detected when bubble reaches after the second duration detecting that liquid reaches and report an error.
2. automatic analysing apparatus according to claim 1, which is characterized in that the control module is for controlling drawing liquid module
Drawing liquid, T0 at the time of record drawing liquid starts are carried out to container；And whether the pipeline is detected by the bubble detecting sensor
There is liquid arrival, is recorded in the pipeline T1 at the time of detecting liquid；If moment T0 starts the bubble after the first duration
Liquid arrival is still not detected in detection sensor, then the control module reports an error.
3. automatic analysing apparatus according to claim 2, which is characterized in that the control module is also used to record bubble inspection
It surveys sensor and detects T2 at the time of the pipeline has bubble arrival after moment T1；Described in if moment T1 starts after the second duration
Bubble arrival is still not detected in bubble detecting sensor, then the control module reports an error.
4. automatic analysing apparatus according to claim 3, which is characterized in that further include the pumping for being stored with the drawing liquid module
The memory of liquid speed degree；The control module, which is also used to subtracting moment T2 into moment T1, obtains this drawing liquid duration, in conjunction with described
Drawing liquid speed calculates this drawing liquid amount.
5. automatic analysing apparatus according to claim 1, which is characterized in that further include liquid detection sensor, for pair
It is detected in container with the presence or absence of liquid.
6. automatic analysing apparatus according to claim 5, which is characterized in that the liquid detection sensor is set to the appearance
It receives below position or the receiving position side.
7. automatic analysing apparatus according to claim 1, which is characterized in that further include the fixation above the turntable
Device, the drawing liquid module and the bubble detecting sensor are installed on the fixed device.
8. automatic analysing apparatus according to claim 1, which is characterized in that the drawing liquid module includes drawing liquid pump, drawing liquid
Needle and the pipeline for being connected to the drawing liquid pump and the liquid pumping needle.
9. a kind of drawing liquid monitoring method, for carrying out drawing liquid monitoring to automatic analysing apparatus, the automatic analysing apparatus includes taking out
Liquid module, which is characterized in that the automatic analysing apparatus further include:
Turntable, the receiving position equipped with multiple holding said containers, each receiving position is for accommodating a container；
Bubble detecting sensor, set on the turntable top, close to drawing liquid module pipeline one end liquid sucting port position, use
Whether there is bubble to detect in the pipeline to the drawing liquid module；
The described method includes:
It controls the drawing liquid module to carry out drawing liquid to container and start timing, if drawing liquid starts the bubble detection after the first duration
Liquid arrival is still not detected in sensor, then reports an error；
If since detect liquid reach start the second duration after, the bubble detecting sensor be still not detected bubble arrival,
It reports an error.
10. according to the method described in claim 9, it is characterized in that, further comprising the steps of:
T0 is recorded as at the time of by the beginning timing；
By it is described detect liquid reach at the time of be recorded as T1.
11. according to the method described in claim 10, it is characterized in that, further comprising the steps of:
By it is described detect bubble reach at the time of be recorded as T2.
12. according to the method for claim 11, which is characterized in that further comprise the steps of:
Obtain the drawing liquid speed of the drawing liquid module；
Moment T2 is subtracted into moment T1 and obtains this drawing liquid duration, calculates this drawing liquid amount in conjunction with the drawing liquid speed.
13. according to the method described in claim 9, it is characterized in that, the control drawing liquid module carries out drawing liquid to container and opens
Before the step of beginning timing, further include the steps that detecting with the presence or absence of liquid in the container, if so then execute control pumping
The step of liquid module carries out drawing liquid and starts timing to container.
14. according to the method described in claim 9, it is characterized in that, the step of the drawing liquid speed for obtaining the drawing liquid module
Suddenly include:
The container for filling liquid is provided, and the volume of the liquid in containers is L；
It controls the drawing liquid module and drawing liquid, Ta at the time of record drawing liquid starts is carried out to the container；
Whether there is liquid arrival by the pipeline that the bubble detecting sensor detects the drawing liquid module, and is recorded in the pipe
Tb at the time of detecting liquid in road；If liquid arrival is still not detected after starting third duration in moment Ta, report an error；
It detects whether the pipeline has bubble arrival by the bubble detecting sensor after the moment Tb, and is recorded in described
Tc at the time of detecting bubble in pipeline；If bubble arrival is still not detected after starting the 4th duration in moment Tb, report an error；
The drawing liquid speed is calculated, the drawing liquid speed, which is equal in volume/pipeline of the liquid in containers, detects gas
Difference at the time of liquid is detected at the time of bubble and in the pipeline.
15. according to the method for claim 14, which is characterized in that the automatic analysing apparatus further includes cleaning solution output mould
The step of block, the offer fills the container of liquid is that the cleaning solution output module injects volume into empty container for L
Cleaning solution.
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| CN110082543B (en) | 2023-08-08 |
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