CN211478348U - Hand-held type glycated haemoglobin detector - Google Patents

Hand-held type glycated haemoglobin detector Download PDF

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Publication number
CN211478348U
CN211478348U CN202020048593.XU CN202020048593U CN211478348U CN 211478348 U CN211478348 U CN 211478348U CN 202020048593 U CN202020048593 U CN 202020048593U CN 211478348 U CN211478348 U CN 211478348U
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hemoglobin
hand
glycosylated hemoglobin
area
held
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Chinese (zh)
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方彭华
闵文
赵媛媛
张婕
韩龙
葛冉
陈良
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Nanjing University Of Chinese Medicine Hanlin College
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Nanjing University Of Chinese Medicine Hanlin College
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Abstract

The utility model belongs to the technical field of medical apparatus, in particular to a hand-held glycosylated hemoglobin detector, which provides the following proposal, comprising; the glycosylated hemoglobin detection card consists of a blood collection area, a hemoglobin separation area and a reaction induction area; a hemoglobin separation zone is arranged at the left side of the blood collection zone; the hemoglobin separation zone is composed of two separation zones which are arranged in parallel up and down; a cell membrane lysate is arranged in the separation area; a filter membrane is arranged at the left side of the hemoglobin separation zone; a reaction induction area is arranged on the left side of the filter membrane; the upper side and the lower side of the reaction induction area are both provided with circuit biological induction sheets; the inner sides of the circuit biological sensing sheets at the upper side and the lower side are provided with a coating known amount of hemoglobin antibodies; the detection is quick and convenient, the cost is lower, the result specificity is high, and the popularization is easy.

Description

Hand-held type glycated haemoglobin detector
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to hand-held type glycated hemoglobin detector.
Background
The existing glycosylated hemoglobin detection method mainly comprises the following steps: ion exchange High Performance Liquid Chromatography (HPLC), immunization, electrophoresis, chromatography, etc. Among them, the HPLC method is a "gold standard" for currently detecting glycated hemoglobin. However, these methods have the disadvantages of multiple steps, high cost, poor specificity, etc., and limit the application of glycated hemoglobin in clinical diagnosis of diabetes, especially in diabetes prevention screening (pre-diabetes), and thus need to be improved.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to prior art's defect and not enough, provide a simple structure, reasonable in design, convenient to use's hand-held type glycated hemoglobin detector, it is swift convenient to detect, and the cost is lower, and the result specificity is high, easily popularizes.
In order to achieve the above object, the utility model adopts the following technical scheme: the portable glycosylated hemoglobin detector comprises a handheld glycosylated hemoglobin detector body and a glycosylated hemoglobin detection card; the glycosylated hemoglobin detection card is inserted in the hand-held glycosylated hemoglobin detector body; the glycosylated hemoglobin detection card consists of a blood collection area, a hemoglobin separation area and a reaction induction area; a hemoglobin separation zone is arranged at the left side of the blood collection zone; the hemoglobin separation zone is composed of two separation zones which are arranged in parallel up and down; a cell membrane lysate is arranged in the separation area; a filter membrane is arranged at the left side of the hemoglobin separation zone; a reaction induction area is arranged on the left side of the filter membrane; the upper side and the lower side of the reaction induction area are both provided with circuit biological induction sheets; the inner sides of the circuit biological sensing sheets at the upper side and the lower side are provided with a coating known amount of hemoglobin antibodies; the upper side and the lower side are oppositely arranged and coated with a known amount of hemoglobin antibodies; the circuit biological induction sheet is connected with the hand-held glycosylated hemoglobin detector body.
Furthermore, a processor is arranged in the hand-held glycosylated hemoglobin detector body; the front surface of the hand-held glycosylated hemoglobin detector body is provided with an electronic display screen; the processor is connected with the electronic display screen; the circuit biological sensing piece is connected with the processor.
Furthermore, the aperture of the filter membrane is 0.1-12 μm; the pore density of the filter membrane was 105-108Per cm2
Furthermore, a switch is arranged at the lower part of the front surface of the handheld glycosylated hemoglobin detector body; a battery is arranged in the hand-held glycosylated hemoglobin detector body; the switch, the electronic display screen and the battery are connected in series to form an electric loop.
Furthermore, a charging port is arranged in the middle of the front side surface of the holding type glycosylated hemoglobin detector body; the battery is connected to the charging port.
After the structure is adopted, the utility model discloses beneficial effect does: a hand-held type glycated hemoglobin detector, it is swift convenient to detect, the cost is lower, the result specificity is high, easily popularizes, the practicality is stronger, the utility model has the advantages of simple structure, it is reasonable to set up, the cost of manufacture is low.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.
FIG. 1 is a schematic diagram of a glycated hemoglobin measurement card according to the present invention.
FIG. 2 is a top view of the portable glycated hemoglobin meter of the present invention.
FIG. 3 is a view showing an internal structure of the portable glycated hemoglobin meter of the present invention.
FIG. 4 is a connection diagram of the portable glycated hemoglobin meter body and the glycated hemoglobin meter of the present invention.
Description of reference numerals:
the portable glycosylated hemoglobin detector comprises a handheld glycosylated hemoglobin detector body 1, a glycosylated hemoglobin detection card 2, a blood collection area 3, a hemoglobin separation area 4, a reaction induction area 5, cell membrane lysate 6, a separation area 7, a filter membrane 8, a circuit biological induction sheet 9, a known amount of coated hemoglobin antibody 10, a processor 11, an electronic display screen 12, a switch 13, a battery 14 and a charging port 15.
Detailed Description
The present invention will be further described with reference to the accompanying drawings.
Referring to fig. 1 to 4, the technical solution adopted by the present embodiment is: the portable glycosylated hemoglobin detector comprises a handheld glycosylated hemoglobin detector body 1 and a glycosylated hemoglobin detection card 2; the glycosylated hemoglobin detection card 2 is inserted into the hand-held glycosylated hemoglobin detector body 1; the glycosylated hemoglobin detection card 2 consists of a blood collection area 3, a hemoglobin separation area 4 and a reaction induction area 5; the left side of the blood collecting area 3 is provided with a hemoglobin separating area 4; after being collected, the blood enters a blood collecting area 3 and then flows to a hemoglobin separating area 4; the hemoglobin separation zone 4 is composed of two separation zones 7 arranged in parallel up and down; a cell membrane lysate 6 is arranged in the separation area 7; cells in the blood will be first lysed by the cell membrane lysate 6 in the separation zone 7; the left side of the hemoglobin separation zone 4 is provided with a filter membrane 8; the cell membrane fragments are filtered by the filter membrane 8 and can not enter the reaction induction area 5, and the protein in the blood gradually enters the reaction induction area 5; the left side of the filter membrane 8 is provided with a reaction induction zone 5; the upper side and the lower side of the reaction induction area 5 are both provided with circuit biological induction sheets 9; the inner sides of the circuit biological sensing sheets 9 at the upper side and the lower side are provided with a known amount of coated hemoglobin antibodies 10; the hemoglobin antibodies 10 coated with known amount are oppositely arranged at the upper and lower sides; the circuit biological induction sheet 9 is connected with the hand-held glycosylated hemoglobin detector body 1; hemoglobin is subjected to antigen-antibody reaction in the reaction induction zone 5 by coating known amounts of hemoglobin antibodies 10 on the upper side and the lower side, and electric signals generated in the reaction process are respectively collected by the circuit biological induction sheets 9 on the upper side and the lower side and are finally transmitted into the handheld glycosylated hemoglobin detector body 1.
Further, a processor 11 is arranged in the hand-held glycated hemoglobin meter body 1; the front of the hand-held glycosylated hemoglobin detector body 1 is provided with an electronic display screen 12; the processor 11 is connected with the electronic display screen 12; the circuit biological induction sheet 9 is connected with the processor 11; the processor 11 processes the electric signal collected by the circuit biological sensing piece 9, calculates the HbA1c value, and displays the value on the electronic display 12.
Further, the aperture of the filter membrane 8 is 8 μm; the pore density of the filter membrane 8 is 106Per cm2
Further, a switch 13 is arranged at the lower part of the front surface of the hand-held glycosylated hemoglobin meter body 1; a battery 14 is arranged in the hand-held glycosylated hemoglobin detector body 1; the switch 13, the electronic display screen 12 and the battery 14 are connected in series to form an electric loop; the opening of the switch 13 is controlled to control the opening of the electronic display 12.
Furthermore, a charging port 15 is arranged in the middle of the front side surface of the holding type glycosylated hemoglobin detector body 1; the battery 14 is connected with the charging port 15; the charging port 15 is connected to a data line to charge the battery 14.
Principle of this embodiment: disinfecting the abdomen of the ring finger by using an alcohol cotton ball, puncturing the skin by using a disposable blood taking needle, enabling 2-3 drops of blood to be close to a blood receiving area, and wiping and disinfecting the finger tips again; inserting the detection card into the detector, waiting for 2min, and displaying the glycosylated hemoglobin result on the electronic display screen 12; after blood is collected, cells in the blood are firstly cracked by the cell membrane lysate 6 in the separation area 7, and cell membrane fragments are filtered by the filter membrane 8 and cannot enter the reaction induction area 5; the protein in the blood gradually enters the reaction induction area 5; the blood is subjected to antigen-antibody reaction in the reaction induction zone 5 by coating known amount of hemoglobin antibodies 10 on the upper and lower sides, and electric signals generated in the reaction process are respectively collected by the circuit biological induction sheets 9 on the upper and lower sides and are transmitted to the handheld glycosylated hemoglobin detector body 1; the total current I1 and the total current I2 of the upper part and the lower part are respectively detected, the basic value I0 is respectively subtracted, the biological current I1-I0 and the biological current I2-I0 are respectively obtained, the I1-I0/I2-I0 value, namely the HbA1c value, is obtained through the processor 11, and then the value is displayed through the electronic display screen 12.
After adopting above-mentioned structure, this embodiment's beneficial effect does:
1. the HbA1c value is obtained through calculation of the side face of the ratio of the current difference and is displayed through the electronic display screen 12, so that the method is simple and clear, and wide in applicability; the bioelectric current sensing is one-to-one, accurate and reliable;
2. after blood sequentially passes through the blood collection area 3, the hemoglobin separation area 4 and the reaction induction area 5, the blood and a known amount of hemoglobin antibody are subjected to antigen-antibody reaction, and an electric signal generated in the reaction process is collected by the circuit biological induction sheet 9 and is transmitted to the handheld glycosylated hemoglobin detector body 1; compared with the prior art, the detection is quick and convenient and the cost is lower.
The above description is only for the purpose of illustrating the technical solutions of the present invention and not for the purpose of limiting the same, and other modifications or equivalent replacements made by those of ordinary skill in the art to the technical solutions of the present invention should be covered within the scope of the claims of the present invention as long as they do not depart from the spirit and scope of the technical solutions of the present invention.

Claims (5)

1. A hand-held glycosylated hemoglobin meter comprises a hand-held glycosylated hemoglobin meter body (1) and a glycosylated hemoglobin meter card (2); the glycosylated hemoglobin detection card (2) is inserted into the hand-held glycosylated hemoglobin detector body (1); the method is characterized in that: the glycosylated hemoglobin detection card (2) consists of a blood collection area (3), a hemoglobin separation area (4) and a reaction induction area (5); a hemoglobin separation zone (4) is arranged at the left side of the blood collection zone (3); the hemoglobin separation zone (4) is composed of two separation zones (7) which are arranged in parallel up and down; a cell membrane lysate (6) is arranged in the separation area (7); a filter membrane (8) is arranged at the left side of the hemoglobin separation zone (4); a reaction induction area (5) is arranged at the left side of the filter membrane (8); the upper side and the lower side of the reaction induction area (5) are provided with circuit biological induction sheets (9); the inner sides of the circuit biological sensing sheets (9) at the upper side and the lower side are provided with hemoglobin antibodies (10) coated with known quantity; the upper side and the lower side are oppositely arranged and coated with a known amount of hemoglobin antibodies (10); the circuit biological induction sheet (9) is connected with the hand-held glycosylated hemoglobin detector body (1).
2. The portable glycated hemoglobin meter of claim 1, wherein: a processor (11) is arranged in the hand-held type glycosylated hemoglobin detector body (1); an electronic display screen (12) is arranged on the front surface of the hand-held type glycosylated hemoglobin detector body (1); the processor (11) is connected with the electronic display screen (12); the circuit biological sensing piece (9) is connected with the processor (11).
3. The portable glycated hemoglobin meter of claim 1, wherein: the aperture of the filter membrane (8) is 0.1-12 μm; the pore density of the filter (8) was 105-108/cm 2.
4. The portable glycated hemoglobin meter of claim 1, wherein: a switch (13) is arranged at the lower part of the front surface of the hand-held type glycosylated hemoglobin detector body (1); a battery (14) is arranged in the hand-held type glycosylated hemoglobin detector body (1); the switch (13), the electronic display screen (12) and the battery (14) are connected in series to form an electric loop.
5. The portable glycated hemoglobin meter of claim 4, wherein: the middle part of the front side surface of the holding type glycosylated hemoglobin detector body (1) is provided with a charging port (15); the battery (14) is connected to the charging port (15).
CN202020048593.XU 2020-01-09 2020-01-09 Hand-held type glycated haemoglobin detector Active CN211478348U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020048593.XU CN211478348U (en) 2020-01-09 2020-01-09 Hand-held type glycated haemoglobin detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020048593.XU CN211478348U (en) 2020-01-09 2020-01-09 Hand-held type glycated haemoglobin detector

Publications (1)

Publication Number Publication Date
CN211478348U true CN211478348U (en) 2020-09-11

Family

ID=72374019

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020048593.XU Active CN211478348U (en) 2020-01-09 2020-01-09 Hand-held type glycated haemoglobin detector

Country Status (1)

Country Link
CN (1) CN211478348U (en)

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