CN211156475U - Pressurizing shell for promoting bone circulation for treating large-section bone defect - Google Patents

Pressurizing shell for promoting bone circulation for treating large-section bone defect Download PDF

Info

Publication number
CN211156475U
CN211156475U CN201921182417.9U CN201921182417U CN211156475U CN 211156475 U CN211156475 U CN 211156475U CN 201921182417 U CN201921182417 U CN 201921182417U CN 211156475 U CN211156475 U CN 211156475U
Authority
CN
China
Prior art keywords
bone
strip
treatment
circulation
strips
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201921182417.9U
Other languages
Chinese (zh)
Inventor
李明
唐佩福
张里程
孙国飞
崔翔
尹鹏滨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinese PLA General Hospital
Original Assignee
Chinese PLA General Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinese PLA General Hospital filed Critical Chinese PLA General Hospital
Priority to CN201921182417.9U priority Critical patent/CN211156475U/en
Application granted granted Critical
Publication of CN211156475U publication Critical patent/CN211156475U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The utility model discloses a forcing bone circulation pressurizing shell for treating large-section bone defect, which comprises an annular structure and a strip-shaped structure arranged between a pair of annular structures, wherein the annular structure and the strip-shaped structure form a relatively closed cavity, and ectopic osteogenesis materials are arranged in the cavity; the strip-like structure is free to flex to pressurize the ectopic osteogenic material in the cavity. The utility model provides a pair of a promote bone circulation pressurization shell for defective treatment of big section bone is applicable to the big section bone defect of dystopy osteogenesis treatment, and its is rational in infrastructure, and design benefit sets up the bar structure between the ring structures and has the elasticity for the dystopy osteogenesis material pressurization that sets up between the ring structures, thereby has promoted the speed and the quality of osteogenesis.

Description

Pressurizing shell for promoting bone circulation for treating large-section bone defect
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a promote bone circulation pressurization shell for defective treatment of big section bone.
Background
With the rapid development of bone tissue engineering in recent years, the bone defect treatment by applying the bone tissue engineering technology is the current development trend, and compared with in-situ osteogenesis, the ectopic osteogenesis model can reduce the variables influencing osteogenesis in experiments and can evaluate the effects of osteogenic stem cells and osteogenesis inducing materials. Ectopic ossification (HO), which is a dynamically developing process, refers to ectopic malformed osteogenesis occurring in normal soft tissues other than bone tissues; ectopic ossification is one of ectopic osteogenesis.
The circulating pressure has important significance on bone regeneration and remodeling, and particularly, how to effectively improve the quality and speed of in-vivo ectopic bone formation is very important for treating large-segment bone defects by using an ectopic bone formation technology. There is currently no mature pressurized shell that promotes bone circulation for the treatment of large bone defects.
The patent CN100571662C discloses a prosthesis for repairing maxillary bone defect and a preparation method thereof, wherein the prosthesis comprises a silicon rubber outer layer adapted to a maxillary bone defect area, a cylindrical skin soft tissue expander inner layer is arranged in the silicon rubber outer layer, the cylindrical skin soft tissue expander inner layer is connected with an air charging device extending out of the silicon rubber outer layer, and the silicon rubber outer layer and the cylindrical skin soft tissue expander inner layer or the air charging device are provided with corresponding magnetic retainers. The invention is only suitable for repairing the jaw bone defect.
Patent CN103992947A discloses a loading device and a loading method for skeletal cell compressive stress in porous titanium alloy, wherein the loading device comprises a servo motor, an action chamber, an action piston, a pressurization chamber, a movable wall plate, a transmission rod, a pressure sensor, a temperature sensor and the like, the servo motor is controlled by a motion control card through a PC and is connected with the transmission rod, the transmission rod is connected with the action piston, and the servo motor drives the piston to move up and down through the transmission rod. The front side wall of the pressurizing chamber is provided with an openable movable wall plate. The device is placed in a cell culture box after disinfection and sterilization, bone cell suspension is planted in the porous titanium alloy, and a pressurizing system stimulates cells in the porous titanium alloy by compression load. The invention discloses a test device, which can not be used for clinical bone defect treatment.
Therefore, there is a need to design a pressurized shell for promoting bone circulation for treating large bone defects, which can effectively improve the quality and speed of ectopic osteogenesis in vivo.
SUMMERY OF THE UTILITY MODEL
The utility model aims at the above-mentioned technical problem, the utility model provides a pair of a promote bone circulation pressurization shell for big section bone defect treatment is applicable to the big section bone defect of dystopy osteogenesis treatment, and its is rational in infrastructure, and design benefit sets up the bar structure between the ring structures and has the elasticity for the dystopy osteogenesis material pressurization between the ring structures sets up, thereby has promoted the speed and the quality of osteogenesis.
In order to solve the technical problem, the utility model provides a promote bone circulation pressurization shell for large bone defect treatment, including annular structure and the strip structure that sets up between a pair of annular structure, annular structure and strip structure form a relative confined cavity, dystopy osteogenesis material sets up in the cavity; the strip-like structure is free to flex to pressurize the ectopic osteogenic material in the cavity.
In some embodiments, the strip-shaped structure is formed by adhering and fixing multiple layers of strips.
In some embodiments, the strips are hydrogel or polymer, and the biogel is disposed between adjacent strips.
In some embodiments, the strip-like structure is stretchable.
In some embodiments, the strip-shaped structure comprises a plurality of strips with different lengths, and the strips are stretched along the length direction to be equal in length and then are bonded and fixed into a whole through biological glue.
In some embodiments, the strip-shaped structure comprises a plurality of strips with different widths, and the strips are stretched to equal lengths along the width direction and then are bonded and fixed into a whole through biological glue.
In some embodiments, the stripe structures are uniformly distributed along the axis of the ring structure as the center.
In some embodiments, the gap between adjacent ones of the stripe structures is adjustable.
In some embodiments, the cross-section of the strip-shaped structure is any one of rectangular, triangular, elliptical and circular.
In some embodiments, the strips with different lengths are fixedly bonded into a whole in the descending or ascending order of the lengths.
In some embodiments, the strips with different widths are adhered and fixed into a whole in the order of decreasing or increasing widths.
The utility model discloses beneficial effect:
the utility model provides a cause bone circulation pressurization shell for defective treatment of big section bone, be applicable to the big section bone of dystopy osteogenesis treatment and be defective, it is rational in infrastructure, design benefit, the bar structure of setting between the ring structure has the elasticity, make the dystopy osteogenesis material pressurization between the setting ring structure, again can be when muscle shrink, under the compression of muscle, make the distance increase between the ring structure, axial pressure diminishes, the radial pressure grow, rely on the flexible intermittent type nature pressure change that produces of muscle itself, clearance between the bar structure is adjustable, make things convenient for the nutrient substance to get into, the discharge of blood vessel growing into and metabolite, thereby the speed and the quality of osteogenesis have been promoted.
Drawings
The above advantages of the present invention will become more apparent and more readily appreciated from the detailed description taken in conjunction with the following drawings, which are given by way of illustration only and do not limit the present invention, and in which:
fig. 1 is a schematic structural view of a pressurized shell for promoting bone circulation for the treatment of a large bone defect according to the present invention;
fig. 2 to 3 are sectional views of the strip-shaped structure of the present invention along the length direction;
FIG. 4 is a cross-sectional view of the strip structure of the present invention along the width direction;
in the figure:
10. a cyclic structure; 20. a strip structure; 21. and (4) strips.
Detailed Description
A pressurized shell for promoting bone circulation for the treatment of a large bone defect according to the present application will be described in detail with reference to the following embodiments and accompanying drawings.
The embodiments described herein are specific embodiments of the present invention, and are intended to be illustrative of the concepts of the present invention, which are intended to be illustrative and exemplary, and should not be construed as limiting the scope of the embodiments of the present invention. In addition to the embodiments described herein, those skilled in the art will be able to employ other technical solutions which are obvious based on the disclosure of the claims and the specification of the present application, and these technical solutions include technical solutions which make any obvious replacement or modification for the embodiments described herein.
The drawings in the present specification are schematic views to assist in explaining the concept of the present invention, and schematically show the shapes of the respective portions and the mutual relationships thereof. Note that, in order to clearly show the structure of each component of the embodiment of the present invention, the same reference numerals are used to denote the same parts.
The structural schematic diagram of the casing for promoting bone circulation pressurization for the treatment of large bone defect of the present invention is shown in fig. 1 to 4, and includes a ring structure 10 and a strip structure 20 disposed between a pair of ring structures 10, wherein the ring structures 10 and the strip structure 20 form a relatively closed cavity, and the ectopic bone formation material is disposed in the cavity; the strip structure 20 is free to flex to compress the ectopic osteogenic material in the cavity.
As an embodiment of the present invention, the strip structure 20 is formed by adhering and fixing multiple layers of strips 21. In the embodiment shown in fig. 2 to 4, the number of the strips 21 is three, and the number of the strips 21 may also be three, four, five, etc.
In one aspect of this embodiment, the strip 21 is a hydrogel or a polymer that is not capable of exclusionary reaction with the body, which is detrimental to the fusion of the ectopic osteogenic material with the body tissue. As another aspect of this embodiment, a bio-gel is disposed between the adjacent strips 21 to ensure rapid fusion of the ectopic osteogenic material with the human tissue.
As an embodiment of the present invention, the strip 21 is stretchable, and the multi-layer strip 21 is stretched along the length direction and/or the width direction and then bonded to other strips 21 during the bonding process, so that the strip structure 20 formed by bonding the multi-layer strip 21 has a stretching property, which can stretch along the length direction and/or the width direction to pressurize the osteogenesis material in the relatively closed cavity formed by the ring structure 10 and the strip structure 20.
As an aspect of the present embodiment, the strip-shaped structure 20 includes a plurality of strips 21 with different lengths, and the strips 21 are stretched along the length direction to be equal in length and then fixed together by biological glue; as shown in fig. 2, the dotted line in the drawing indicates a state in which the bar 21 is stretched in the length direction, the solid line indicates a state in which the bar 21 is not stretched, the bar 21 with a shorter length is stretched in the length direction to be equal to a corresponding length of the bar 21 with a longer length, and the bars are bonded and fixed together by using the bio-adhesive, so that the bar structure 20 formed by bonding the plurality of layers of bars 21 has elasticity, and can be stretched in the length direction to pressurize the osteogenic material in the relatively closed cavity formed by the ring structure 10 and the bar structure 20.
The strip-shaped structure 20 comprises a plurality of strips 21 with different widths, and the strips 21 are stretched along the width direction to be equal in length and then are bonded and fixed into a whole through biological glue; as shown in fig. 4, the dotted line in the drawing indicates a state where the bar 21 is stretched in the width direction, the solid line indicates a state where the bar 21 is not stretched, the bar 21 with a shorter width is stretched in the width direction to be equal to the corresponding width of the bar 21 with a longer width, and the bars are bonded and fixed together by using the bio-adhesive, so that the bar structure 20 formed by bonding the plurality of layers of bars 21 has elasticity, and can be stretched in the width direction to pressurize the osteogenic material in the relatively closed cavity formed by the ring structure 10 and the bar structure 20.
In the embodiment shown in fig. 1, the strip structures 20 are uniformly distributed along the axis of the ring structure 10, and the strip structures 20 can be freely stretched and contracted to pressurize the ectopic bone formation material in the cavity, as a variation of this embodiment, the strip structures 20 can also be non-uniformly distributed along the axis of the ring structure 10, as long as the gap between the adjacent strip structures 20 is ensured to be 1mm-5mm, and the strip structures 20 can be freely stretched and contracted to pressurize the ectopic bone formation material in the cavity.
In the present invention, the gap between the adjacent strip structures 20 is adjustable. Specifically, in the embodiment shown in fig. 4, the strip structures 20 are stretchable in the width direction, so that the gap adjustment of the adjacent strip structures 20 is realized by stretching the strip structures 20 in the width direction.
As an embodiment of the present invention, the cross section of the strip-shaped structure 20 is any one of a rectangle, a triangle, an ellipse, and a circle. It should be understood that the cross section of the strip-shaped structure 20 may also be other closed shapes, such as a trapezoid shape, a combined rectangular shape and a semicircular shape, so long as the strip-shaped structure 20 is convenient to adhere and fix and the strip-shaped structure 20 formed by adhesion has good elasticity.
As an embodiment of the present invention, the bars 21 with different lengths are bonded and fixed together according to the decreasing or increasing length sequence, as shown in fig. 2; as a variation of this embodiment, the strips 21 may be adhered and fixed in other arrangements, for example, they are symmetrically distributed in a descending or ascending order, as shown in fig. 3, so that the strips 21 on both sides have shorter lengths, and the strips 21 with shorter lengths on both sides are stretched and then fixed with the strips 21 with longer lengths in the middle by using biological glue, so as to ensure good flexibility.
The strips 21 with different widths are bonded and fixed into a whole according to the descending or ascending order of the widths, as shown in fig. 4; as a variation of this embodiment, the strips 21 may also be adhered and fixed in other arrangements, for example, symmetrically distributed in descending or ascending order, so that the strips 21 on both sides have shorter width, and the strips 21 with shorter width on both sides are stretched and then fixed with the strips 21 with longer width in the middle by using biological glue, and good elasticity can also be ensured.
A promote bone circulation pressurization shell for big section bone defect treatment move towards the setting along the muscle, then when muscle contraction, bar structure 20 realizes length grow under the effect of muscle extrusion force, along the axial pressure reduction of dystopy osteogenesis material, and radial pressure increase, like this along with the intermittent type shrink of muscle, alright radial and the axial formation intermittent type circulation pressure at dystopy osteogenesis material has accelerated the comprehensive exchange of material, has promoted osteogenesis speed and quality. In the present invention, fig. 1 shows an embodiment of a pair of ring structures 10, which may also include a plurality of ring structures 10, and a plurality of strip structures 20 are disposed between adjacent ring structures 10, so as to form a circulation pressure device with a longer length, so as to be suitable for treating bone defects of different forms.
The use steps and the process of the bone circulation promoting pressurizing shell for the treatment of the large bone defect are as follows:
performing ectopic osteogenesis in an operation room special for experimental animals irradiated by ultraviolet rays, and after anesthesia takes effect, preparing skin of an operation area by using a shaver special for animals;
lying a New Zealand white rabbit on a surgical operation table, disinfecting skin within a range by using medical iodine tincture, and conventionally paving a towel to expose the back of an experimental animal;
making two incisions with the length of about 2cm on two sides of the back spinal column, lifting the skin, separating subcutaneous tissue and superficial fascia by using vascular forceps and tissue scissors, and reaching deep fat layer until the superficial fascia of muscle is exposed;
separating the outlet bag-shaped muscle bag by using a passive separator, infiltrating the tissue engineering scaffold loaded in the device with physiological saline, then horizontally putting the tissue engineering scaffold into the muscle bag, arranging a circulating pressure device along the trend of the muscle, then suturing the wound layer by layer, and marking.
The utility model provides a pair of a promote bone circulation pressurization shell for defective treatment of big section bone is applicable to the big section bone defect of dystopy osteogenesis treatment, and its is rational in infrastructure, and design benefit sets up the bar structure between the ring structures and has the elasticity for the dystopy osteogenesis material pressurization that sets up between the ring structures, thereby has promoted the speed and the quality of osteogenesis, has better spreading value.
The present invention is not limited to the above embodiments, and any person can obtain other products in various forms without departing from the scope of the present invention, but any change in shape or structure is included in the technical solution that is the same as or similar to the present invention.

Claims (11)

1. A pressurized shell for promoting bone circulation for the treatment of a large bone defect, comprising: the bone-knitting machine comprises annular structures and strip-shaped structures arranged between a pair of annular structures, wherein the annular structures and the strip-shaped structures form a relatively closed cavity, and ectopic bone-forming materials are arranged in the cavity; the strip-like structure is free to flex to pressurize the ectopic osteogenic material in the cavity.
2. The bone circulation-promoting compression shell for treatment of a large bone defect of claim 1, wherein the strip structure is adhesively secured by a plurality of layers of strips.
3. The bone circulation-promoting compression shell for treatment of a large bone defect of claim 2, wherein the strips are hydrogel or high polymer, and a bio-gel is disposed between adjacent strips.
4. The bone circulation-promoting compression shell for treatment of a large bone defect of claim 1, wherein the strip structure is stretchable.
5. The bone circulation-promoting compression casing for the treatment of a segmental bone defect of claim 1, wherein the strip structure comprises a plurality of strips of different lengths, and the strips are stretched to equal lengths along the length direction and then are bonded and fixed into a whole by biological glue.
6. The bone circulation-promoting compression casing for the treatment of a segmental bone defect of claim 1, wherein the strip-like structure comprises a plurality of strips of different widths, and the strips are stretched to equal lengths in the width direction and then are bonded and fixed into a whole by biological glue.
7. The bone circulation-promoting compression sheath for the treatment of a large bone defect of claim 1, wherein the strip-like structures are evenly distributed centered along the axis of the ring-like structure.
8. The bone circulation-promoting compression sheath for the treatment of a large bone defect of claim 1, wherein the gap between adjacent ones of the strip-like structures is adjustable.
9. The bone circulation-promoting compression sheath for the treatment of a large bone defect of claim 1, wherein the cross-section of the strip-like structure is any one of rectangular, triangular, oval and circular.
10. The bone circulation-promoting compression sheath for the treatment of a large bone defect of claim 5, wherein the bars of different lengths are adhesively secured together in a descending or ascending order of length.
11. The bone circulation-promoting compression sheath for the treatment of a large bone defect of claim 6, wherein the strips of different widths are adhesively secured together in a descending or ascending order of width.
CN201921182417.9U 2019-07-25 2019-07-25 Pressurizing shell for promoting bone circulation for treating large-section bone defect Active CN211156475U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201921182417.9U CN211156475U (en) 2019-07-25 2019-07-25 Pressurizing shell for promoting bone circulation for treating large-section bone defect

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921182417.9U CN211156475U (en) 2019-07-25 2019-07-25 Pressurizing shell for promoting bone circulation for treating large-section bone defect

Publications (1)

Publication Number Publication Date
CN211156475U true CN211156475U (en) 2020-08-04

Family

ID=71787773

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201921182417.9U Active CN211156475U (en) 2019-07-25 2019-07-25 Pressurizing shell for promoting bone circulation for treating large-section bone defect

Country Status (1)

Country Link
CN (1) CN211156475U (en)

Similar Documents

Publication Publication Date Title
US20220039937A1 (en) Method and devices for tissue expansion
EP3034038B1 (en) Breast prosthesis support device based on tissue matrix material, and preparation method therefor
CN108355171B (en) Acellular dermal matrix guided tissue regeneration membrane material and preparation method and application thereof
US20030108587A1 (en) Methods and apparatus for application of micro-mechanical forces to tissues
JP7171612B2 (en) Methods and molds for manufacturing, making and/or producing multi-component implants, devices, structures or materials
US8821573B2 (en) Method and devices for tissue expansion
CN211156475U (en) Pressurizing shell for promoting bone circulation for treating large-section bone defect
JP2018500106A (en) Implants for lymph node formation / regeneration
CN2432908Y (en) Catabolite artificial pyramid
CN206761975U (en) Artificial heart
CN110433012A (en) It is a kind of to facilitate bone to recycle pressurized casing for large segmental bone defect treatment
Martini et al. Tissue regeneration in the reconstruction of lost bone and soft tissue in the lower limbs: a preliminary report
Atsumi et al. Application of specially cross-linked natural rubber for artificial internal organs
CN210843630U (en) Auxiliary in-vivo ectopic osteogenesis device for treating large-section bone defect
CN110478089A (en) A kind of vascularization neuralization osteogenic activity bracket suitable for large segmental bone defect reparation
CN211834530U (en) Incision retracting and fixing device
CN211433515U (en) Intramuscular osteogenesis device for treating large-section bone defect
AU2017204616B2 (en) Method and devices for tissue expansion
RU2198617C2 (en) Method for surgical treatment of osseous cyst
RU41251U1 (en) COMPRESSION PLATE FOR FIXING SKIN TRANSPLANTS IN PLASTIC SURGERY IN ORBITAL AND PARAORBITAL REGIONS
Zolkin Study of graphite materials to be used in medicine
TWI507181B (en) System for manufacturing high strength tissue engineering material via mechanical stimulation in abdominal cavity
CN110433011A (en) It is a kind of for large segmental bone defect treatment auxiliary body in ectopic osteogenesis device
RU2281050C2 (en) Method for modeling the substitution of long tubular bone's defect
Yildiz NERVE IMPLANTS

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant