CN211155917U

CN211155917U - Sampler for collecting samples in molecular diagnosis

Info

Publication number: CN211155917U
Application number: CN201921016325.3U
Authority: CN
Inventors: 徐克琳
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-07-02
Filing date: 2019-07-02
Publication date: 2020-08-04
Anticipated expiration: 2029-07-02

Abstract

The utility model provides a sampler for sample collection in molecular diagnosis, which comprises a push cylinder and a collection head; the push cylinder comprises a cylindrical cylinder, a matched piston is connected in the cylindrical cylinder in a sliding manner, a piston rod is fixed at the upper end of the piston, and a connecting pipe is communicated with the lower end of the cylindrical cylinder; the collecting head comprises a cylindrical head and an arc-shaped sealing head, the arc-shaped sealing head is fixed at the lower end of the cylindrical head, a cavity is arranged in the cylindrical head, a thread groove is formed in the outer side wall of the cylindrical head, a connecting part between the thread groove and the cavity is an elastic film, the elastic film is fixedly connected with the cylindrical head, a cylindrical head connecting pipe is fixed at the top end of the cylindrical head, and the cylindrical head connecting pipe is communicated with the cavity and is in threaded connection with the connecting pipe; the utility model discloses sample thief simple structure, it is convenient to gather the sample, need not to separate the sample through other splitter again.

Description

Sampler for collecting samples in molecular diagnosis

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to sample thief for sample acquisition in molecular diagnosis.

Background

Molecular diagnostics refers to techniques for making a diagnosis by detecting changes in the structure or expression level of genetic material in a patient using molecular biology methods. Molecular diagnosis is a main method for prediction diagnosis, and can be used for diagnosis of individual genetic diseases and prenatal diagnosis. Molecular diagnostics mainly refers to the detection of genes encoding various structural proteins, enzymes, antigens, antibodies, and immunologically active molecules associated with diseases.

Proper sample collection is critical to ensure sample integrity and accuracy of qualitative/quantitative detection of nucleic acids. At present, medical swabs are mostly adopted when samples are collected, protein components and the like are easy to absorb when the swabs collect the samples, the samples are not convenient to separate, and the accuracy of detection results is influenced; meanwhile, after the cotton swab collects the sample, the cotton swab head with the collected sample needs to be cut off, and then the cotton swab head is placed in centrifugal equipment to separate the sample, so that the use is inconvenient.

The Chinese patent with the application number of 201420697014.9 discloses a sampler for sample collection in molecular diagnosis, which comprises an outer tube, a sampling head and a push rod, wherein the outer tube is provided with a tube cavity extending along the length direction of the outer tube, the sampling head comprises a sampling head body which is detachable from the lower end of the outer tube, and the surface of the sampling head body is provided with villi for collecting samples; the push rod is arranged in the tube cavity of the outer tube in a sliding mode, the upper end of the push rod is exposed outside the outer tube, and the lower end of the push rod is in contact with the sampling head, so that the sampling head can be separated from the outer tube in a pushing mode under the action of external force. Human tissues cannot be damaged during sampling by the collector, the cost of other proteins cannot be collected, and meanwhile, samples on the fluff are easier to separate relative to cotton swabs, and the detection result is more accurate and reliable. In addition, the use is more convenient, and the applicability is strong. However, the fluff is still filamentous and is still difficult to separate.

SUMMERY OF THE UTILITY MODEL

The utility model provides a sample thief for sample collection among molecular diagnosis, simple structure, it is convenient to gather the sample, need not to separate the sample through other splitter again.

In order to achieve the above object, the utility model provides a following technical scheme:

a sampler for collecting samples in molecular diagnosis comprises a push cylinder and a collecting head;

the push cylinder comprises a cylindrical cylinder, a matched piston is connected in the cylindrical cylinder in a sliding mode, a piston rod is fixed at the upper end of the piston, and a connecting pipe is communicated with the lower end of the cylindrical cylinder;

the collecting head comprises a cylindrical head and an arc-shaped sealing head, the arc-shaped sealing head is fixed at the lower end of the cylindrical head, a cavity is formed in the cylindrical head, a thread groove is formed in the outer side wall of the cylindrical head, a connecting part between the thread groove and the cavity is an elastic film, the elastic film is fixedly connected with the cylindrical head, a cylindrical head connecting pipe is fixed at the top end of the cylindrical head, and the cylindrical head connecting pipe is communicated with the cavity and is in threaded connection with the connecting pipe.

Furthermore, a pull ring is fixed at the top end of the piston rod.

Further, the elastic film is an elastic rubber film.

Further, an inner cavity is arranged in the arc-shaped sealing head and communicated with the cavity, and a through hole is formed in the bottom end of the arc-shaped sealing head.

Further, a threaded pipe is communicated with the through hole of the inner cavity, a threaded rod is connected with the inner thread of the threaded pipe, extends to the outside of the arc-shaped sealing head, and is fixed with a rotating handle at the bottom end of the threaded rod.

Further, the arc-shaped end socket is made of rubber.

The utility model has the advantages that:

use the utility model discloses during the collector, the sample that strikes off from gathering the position has great part to gather in the thread groove, after the sampling is accomplished, can use the article of thin wire class to scrape out the material of thread groove on the one hand, on the other hand when gathering the thing and comparatively difficultly striking off at the thread groove bottom, can promote the piston, make elastic film bulge from the thread groove to can strike off the sample that the thread groove bottom was gathered, simultaneously to the not high sample of adhesion, when elastic film bulges, can fall automatically in collecting container. The utility model discloses still can gather the liquid sample. The utility model discloses when the sample thief carried out sample collection, it is very convenient, need not to separate the sample through other splitter again.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic structural view of the pick head of the present invention;

FIG. 3 is a schematic structural view of the pick head of the present invention after the elastic film bulges out;

FIG. 4 is another schematic structural view of FIG. 3;

in the figure: 1. a push cylinder; 11. a cylindrical barrel; 12. a piston; 13. a piston rod; 14. a connecting pipe; 15. a pull ring; 2. a pick head; 21. a cylindrical head; 211. a cavity; 212. a thread groove; 213. an elastic film; 214. a cylindrical head connection pipe; 22. an arc-shaped end enclosure; 221. an inner cavity; 222. a through hole; 223. a threaded pipe; 224. a threaded rod; 225. and (7) rotating a handle.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

As shown in FIGS. 1-4, a sampler for sample collection in molecular diagnostics comprises a push cylinder 1 and a collection head 2.

The pushing cylinder 1 comprises a cylindrical cylinder 11, a matched piston 12 is connected in the cylindrical cylinder 11 in a sliding mode, a piston rod 13 is fixed at the upper end of the piston 12, a pull ring 15 is fixed at the top end of the piston rod 13, and a connecting pipe 14 is communicated with the lower end of the cylindrical cylinder 11.

The collecting head 2 comprises a cylindrical head 21 and an arc-shaped sealing head 22, the arc-shaped sealing head 22 is fixed at the lower end of the cylindrical head 21, a cavity 211 is arranged in the cylindrical head 21, a thread groove 212 is formed in the outer side wall of the cylindrical head 21, a connecting part between the thread groove 212 and the cavity 211 is an elastic film 213, the elastic film 213 is fixedly connected with the cylindrical head 21, and the elastic film 213 is an elastic rubber film.

The top end of the cylindrical head 21 is fixed with a cylindrical head connecting pipe 214, and the cylindrical head connecting pipe 214 is communicated with the cavity 211 and is in threaded connection with the connecting pipe 14.

The utility model discloses in, when carrying out sample collection, earlier with piston 12 toward drawing outward, make the cylindricality section of thick bamboo 11 in have more air. Then the cylindrical head connecting pipe 214 is in threaded connection with the connecting pipe 14, so that the collecting head 2 is detachably connected with the push cylinder 1. Then, the cylindrical barrel 11 is held by hand, the cylindrical head 21 is placed at the sampling position of the human body, then the cylindrical barrel 11 is rotated, and in the rotating process, the edge angle formed by the thread groove 212 and the cylindrical head 21 can form a certain scraping effect on the human body, a greater portion of the sample scraped from the collection site is thus collected in the threaded groove 212, and, after sampling is completed, on one hand, the material in the threaded groove 212 can be scraped out by using a thin steel wire object, on the other hand, when the collected material is difficult to scrape at the bottom of the threaded groove 212, the piston 12 is pushed, air enters the cavity 211, and then pressure is applied to the elastic membrane 213 connected to the cavity 211, so that the elastic membrane 213 is bulged out from the screw groove 212, thereby scraping off the accumulated sample at the bottom of the screw groove 212, meanwhile, for a sample with low adhesiveness, the sample may automatically fall into the collection container when the elastic film 213 bulges out. It is visible to use the utility model discloses when the sample thief carries out sample acquisition, it is very convenient, need not to separate the sample through other splitter again.

Further, be equipped with inner chamber 221 in arc head 22, inner chamber 221 is linked together with cavity 211, and through-hole 222 has been seted up to arc head 22 bottom, and above-mentioned relates to can conveniently be to the collection of liquid sample, earlier outwards draws piston 12 during the sampling, then installs the collecting head 2, aims at the sample position with through-hole 222 again, then takes a sample, pushes out arc head 22 with the liquid sample after the sample is accomplished and collects.

After the through hole 222 is provided, the through hole 222 is ventilated, so that the elastic film 213 is not beneficial to bulging out of the thread groove 212, a thread pipe 223 is communicated with the through hole 222 of the inner cavity 221, a thread rod 224 is connected with the thread pipe 223 in a threaded manner, the thread rod 224 extends out of the arc-shaped end enclosure 22, and a rotating handle 225 is fixed at the bottom end of the thread rod 224. Thus, after sampling using the cylindrical head 21, the threaded rod 224 can be screwed into the threaded tube 223 through the through hole 222, thereby blocking the through hole 222.

In the present invention, the arc-shaped sealing head 22 is made of rubber.

The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims

1. A sampler for collecting samples in molecular diagnosis is characterized by comprising a push cylinder (1) and a collecting head (2);

the push cylinder (1) comprises a cylindrical cylinder (11), a matched piston (12) is connected in the cylindrical cylinder (11) in a sliding mode, a piston rod (13) is fixed at the upper end of the piston (12), and a connecting pipe (14) is communicated with the lower end of the cylindrical cylinder (11);

the collecting head (2) comprises a cylindrical head (21) and an arc-shaped sealing head (22), the lower end of the cylindrical head (21) is fixed with the arc-shaped sealing head (22), a cavity (211) is arranged in the cylindrical head (21), a thread groove (212) is formed in the outer side wall of the cylindrical head (21), a connecting part between the thread groove (212) and the cavity (211) is an elastic film (213), the elastic film (213) is fixedly connected with the cylindrical head (21), a cylindrical head connecting pipe (214) is fixed at the top end of the cylindrical head (21), and the cylindrical head connecting pipe (214) is communicated with the cavity (211) and is in threaded connection with the connecting pipe (14).

2. Sampler for sample collection in molecular diagnostics according to claim 1, characterized in that a pull ring (15) is fixed to the top end of the piston rod (13).

3. Sampler for sample collection in molecular diagnostics as claimed in claim 1, characterized in that the elastic membrane (213) is an elastic rubber membrane.

4. The sampler for collecting samples in molecular diagnosis according to claim 1, wherein the arc-shaped sealing head (22) is internally provided with an inner cavity (221), the inner cavity (221) is communicated with the cavity (211), and the bottom end of the arc-shaped sealing head (22) is provided with a through hole (222).

5. The sampler for collecting samples in molecular diagnostics according to claim 4, characterized in that a threaded tube (223) is connected to the through hole (222) of the inner cavity (221), a threaded rod (224) is connected to the threaded tube (223) in a threaded manner, and the threaded rod (224) extends out of the arc-shaped end socket (22) and is fixed with a rotating handle (225) at the bottom end thereof.

6. Sampler for sample collection in molecular diagnostics according to claim 1 characterized in that the dome (22) is made of rubber.