CN211051534U - Automatic liquid transfer equipment - Google Patents
Automatic liquid transfer equipment Download PDFInfo
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- CN211051534U CN211051534U CN201921695267.1U CN201921695267U CN211051534U CN 211051534 U CN211051534 U CN 211051534U CN 201921695267 U CN201921695267 U CN 201921695267U CN 211051534 U CN211051534 U CN 211051534U
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Abstract
The utility model discloses an automatic liquid-transfering device, which comprises a liquid-feeding mechanism, a liquid-transfering mechanism, a liquid-receiving mechanism, a cleaning mechanism and a control mechanism; the first objective table rotates around the central axis of the first objective table; the liquid transfer mechanism comprises a second base, a first mounting frame, a second driving mechanism and an air pump, the first mounting frame rotates around the central axis of the second base, and the air pump is fixedly arranged on the first mounting frame; the liquid transfer tube is driven by the lifting mechanism to do linear motion in the vertical direction, the high-level end of the liquid transfer tube is communicated with the air vent of the air pump, and the liquid level sensor is used for measuring the height of the solution in the liquid transfer tube; the liquid receiving mechanism comprises a third driving mechanism, a fourth driving mechanism and a second objective table, and the cleaning mechanism is used for cleaning the pipette. Improve through setting up a plurality of liquid-transfering components and move liquid efficiency, set up cleaning equipment washing pipette simultaneously, reduce the consumption of disposable tip, compare the transmission moreover and move liquid equipment and install additional more easily in current fume hood.
Description
Technical Field
The utility model belongs to the technical field of move the liquid device, concretely relates to automatic move liquid equipment.
Background
In biological and chemical experiments, volatile toxic and harmful substances (such as hydrofluoric acid, benzene and benzene homologues, cyanogen and nitrile compounds and the like) are sometimes used, and when the operations of pipetting, diluting, mixing and the like are carried out on the solutions, the operations are usually carried out in a fume hood, and protective measures are taken. However, since the experimenter is in close contact with the toxic substances for a long time, the toxic substances volatilized in the air are easily sucked in due to negligence or misoperation in the operation process, and the physical health of the experimenter is threatened. Especially for novices with less experiment experience, the experiment process has larger potential safety risk.
The problem can be fundamentally solved by additionally arranging the automatic pipetting device in a fume hood, but the conventional automatic pipetting device usually superposes three linear driving mechanisms to respectively drive a pipetting gun to move in the direction X, Y, Z, so that automatic pipetting is realized. This structure mainly has the following problems: firstly, the structure releases the solution to the test tube that connects the liquid and then gets the liquid again in the return stroke be unloaded, that is to say, half the journey is unloaded in the action mechanism motion process, and it is not high to move liquid efficiency, and it is longer relatively to move liquid time. Secondly, the device has compact structure, is difficult to arrange a mechanism for cleaning the pipette, directly changes the disposable suction head on the pipette when the solution to be transferred is changed, and has large resource consumption and high use cost.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a: the problem of solve not enough among the above-mentioned prior art, provide an automatic move liquid equipment, improve through setting up a plurality of liquid subassemblies that move and move liquid efficiency, set up cleaning equipment washing pipette simultaneously, reduce the consumption of disposable suction head.
In order to realize the purpose, the utility model discloses a technical scheme be: an automatic liquid-transfering equipment, including liquid-feeding mechanism, liquid-transfering mechanism, liquid-receiving mechanism, cleaning mechanism and control mechanism; the liquid feeding mechanism comprises a first base, a first driving mechanism and a circular first object stage, the first base is fixedly arranged, the first object stage is rotatably connected with the first base, the first object stage is in transmission connection with a power output end of the first driving mechanism, and the first object stage is driven by the first driving mechanism to rotate around the central axis of the first object stage; the liquid transfer mechanism comprises a second base, a first mounting frame, a second driving mechanism and an air pump, the second base is fixedly arranged, the first mounting frame is rotatably connected with the second base, the first mounting frame is in transmission connection with a power output end of the second driving mechanism, the first mounting frame is driven by the second driving mechanism to rotate around the central axis of the second base, and the air pump is fixedly arranged on the first mounting frame; the first mounting frame is symmetrically provided with a plurality of liquid transfer assemblies, each liquid transfer assembly comprises a pipette, a liquid level sensor and a lifting mechanism, the lifting mechanism is fixedly connected with the first mounting frame, the pipette is in transmission connection with the power output end of the lifting mechanism, the pipette is driven by the lifting mechanism to do linear motion in the vertical direction, the high-level end of the pipette is communicated with the air vent of the air pump, and the liquid level sensors are used for measuring the height of the solution in the pipette; the liquid receiving mechanism comprises a third driving mechanism, a fourth driving mechanism and a second objective table, the second objective table is in transmission connection with a power output end of the third driving mechanism, the second objective table is driven by the third driving mechanism to perform linear motion along a first preset direction, a machine body of the third driving mechanism is in transmission connection with a power output end of the fourth driving mechanism, the third driving mechanism and the second objective table are driven by the fourth driving mechanism to perform linear motion along a second preset direction, and the first preset direction is perpendicular to the second preset direction; the cleaning mechanism is used for cleaning the pipette, the cleaning mechanism comprises a cleaning barrel, a water inlet pipe and a water outlet pipe, an opening is formed in the top of the cleaning barrel, the water inlet pipe is communicated with the high-position end of the cleaning barrel, a first electromagnetic valve is arranged on the water inlet pipe, the water outlet pipe is communicated with the low-position end of the cleaning barrel, and a second electromagnetic valve is arranged on the water outlet pipe; the liquid feeding mechanism, the liquid receiving mechanism and the cleaning mechanism are all positioned below the liquid transferring assembly, when one pipette moves to the position right above the first objective table, the other pipette is positioned right above the second objective table; the signal input end of the first driving mechanism, the signal input end of the second driving mechanism, the signal input end of the lifting mechanism, the signal input end of the air pump, the signal input end of the third driving mechanism, the signal input end of the fourth driving mechanism, the signal input end of the first electromagnetic valve and the signal input end of the second electromagnetic valve are all connected with the signal output end of the control mechanism, and the signal output end of the liquid level sensor is connected with the signal input end of the control mechanism.
Furthermore, first base is equipped with annular bearing platform, the bearing platform with first objective table corresponds the setting, the bottom of first objective table through thrust bearing with the top swivelling joint of bearing platform.
Furthermore, the first driving mechanism is a motor, a rotating shaft of the first driving mechanism is provided with a driving gear, the middle part of the first base is provided with an accommodating cavity, and a machine body of the first driving mechanism is fixedly arranged in the accommodating cavity; first objective table with be equipped with the gear circle between the thrust bearing, the gear circle with first objective table fixed connection, drive gear with the inboard meshing of gear circle.
Furthermore, a limiting groove is formed in the first objective table, a plurality of limiting grooves are uniformly distributed along the circumferential direction of the first objective table, and a positioning buckle is arranged in each limiting groove; the positioning buckle comprises a chassis and elastic pieces, the chassis is fixedly connected with the bottom of the limiting groove, the elastic pieces are S-shaped, the fixed ends of the elastic pieces are fixedly connected with the chassis, the free ends of the elastic pieces extend out of the limiting groove, and the elastic pieces are uniformly arranged along the circumferential direction of the chassis.
Furthermore, the second base is cylindrical, the first mounting frame comprises a rotating table, a connecting rod and an annular mounting plate, the rotating table is of a cylindrical structure with an opening at the bottom, the rotating table is fixedly connected with the mounting plate through the connecting rod, and the central axis of the rotating table is collinear with the central axis of the mounting plate; the rotating platform is sleeved at the top of the second base, a first bearing is arranged between the peripheral wall of the second base and the peripheral wall of the rotating platform, and a second bearing is arranged between the top of the second base and the bottom of the rotating platform.
Further, the lifting mechanism comprises a bracket, a first driving motor, a first transmission screw rod and a sliding rod; the support and the body of the first driving motor are fixedly connected with the first mounting frame, the first transmission screw rod is rotatably connected with the support, the first transmission screw rod is in transmission connection with a rotating shaft of the first driving motor, and the first transmission screw rod is driven by the first driving motor to rotate around the central axis of the first transmission screw rod; the bracket is provided with a limiting through hole, the sliding rod penetrates through the limiting through hole and is arranged in parallel with the first transmission screw rod, the middle part of the sliding rod is fixedly provided with a connecting piece, the connecting piece is provided with a first thread through hole matched with the first transmission screw rod, and the first transmission screw rod penetrates through the first thread through hole; the high-position end of the pipette is fixedly connected with the low-position end of the sliding rod, and the pipette is parallel to the sliding rod.
Further, the liquid level sensor is an ultrasonic liquid level sensor, and the ultrasonic liquid level sensor is fixedly arranged at the top of the pipette.
Further, the third driving mechanism comprises a second mounting frame, a second transmission screw rod, a first guide shaft and a second driving motor, wherein the body of the second driving motor and the first guide shaft are fixedly connected with the second mounting frame, the second transmission screw rod is parallel to the first guide shaft, the second transmission screw rod is rotatably connected with the second mounting frame, the second transmission screw rod is in transmission connection with a rotating shaft of the second driving motor, and the second transmission screw rod is driven by the second driving motor to rotate around the central axis of the second transmission screw rod; the second objective table is located first guiding axle with between the second transmission lead screw, the second objective table is close to one side middle part of first guiding axle is equipped with first connecting sleeve, first connecting sleeve cover is located first guiding axle, the second objective table is close to one side middle part of second transmission lead screw is equipped with the second connecting sleeve, the second connecting sleeve cover is located the second transmission lead screw, the inner wall of second connecting sleeve be equipped with second transmission lead screw matched with screw thread.
Further, the fourth driving mechanism comprises a third mounting frame, a third transmission screw rod, a second guide shaft and a third driving motor, the body of the third driving motor and the second guide shaft are both fixedly connected with the third mounting frame, the second guide shaft is perpendicular to the first guide shaft, the third transmission screw rod is parallel to the second guide shaft, the third transmission screw rod is rotatably connected with the third mounting frame, the third transmission screw rod is in transmission connection with a rotating shaft of the third driving motor, and the third mounting frame is driven by the third driving motor to rotate around the central axis of the third mounting frame; the second mounting bracket is provided with a guide through hole matched with the second guide shaft and a second thread through hole matched with the third transmission screw rod, the second guide shaft penetrates through the guide through hole, and the third transmission screw rod penetrates through the second thread through hole.
Furthermore, the inner wall of the cleaning barrel is provided with a speed reduction screw, and the speed reduction screw is positioned at the upper part of the cleaning barrel.
Since the technical scheme is used, the beneficial effects of the utility model are that:
(1) the liquid feeding container and the liquid receiving container of the existing automatic liquid moving equipment are both statically placed on an operation platform and completely absorb the solution to transfer by virtue of an action mechanism at the top, so that the movement track of the action mechanism is required to completely cover a liquid feeding area for placing the liquid feeding container and a liquid receiving area for placing the liquid receiving container, when the areas of the liquid feeding area and the liquid receiving area are large, the operation space required by the whole automatic liquid moving equipment is large, and if the automatic liquid moving equipment is additionally arranged in an existing fume hood, the stroke of the action mechanism is easy to interfere with the top of the fume hood; the liquid feeding mechanism and the liquid receiving mechanism of the utility model can move and work together with the liquid transferring mechanism, the movement track of the pipette arranged above the liquid feeding mechanism and the liquid receiving mechanism does not need to be completely covered, the required operation space is smaller, and the liquid feeding mechanism and the liquid receiving mechanism are easier to be additionally arranged in the existing fume hood;
(2) when a plurality of containers are placed in the device at the same time, part of the containers are inevitably positioned at the inner side of the fume hood, and as the liquid feeding area and the liquid receiving area of the conventional automatic liquid transferring device are static, and the body of an experimenter needs to stretch into the fume hood in the process of placing and retrieving the solution containers, the toxic substances are also sucked by mistake, but the utility model discloses a liquid feeding mechanism and the liquid receiving mechanism can move, the limiting grooves can move to the front end close to the fume hood in sequence, the second objective table can also move to the position close to the front end of the fume hood under the driving of the driving mechanism, so that the experimenter can place or retrieve the containers outside the fume hood, and the safety in the experimental process is further improved;
(3) the plurality of pipetting components are symmetrically arranged, when one pipette moves right above the first objective table, the other pipette is simultaneously positioned right above the second objective table, so that when the pipette sucks liquid, the other pipette releases the solution, the first mounting frame can always drive the pipette to carry out pipetting operation in the rotating process, no idle stroke exists, the pipetting efficiency of the equipment is high, and the pipetting time is shorter;
(4) the first objective table is circular, when one pipette is positioned right above the second objective table, only the other pipette needs to be aligned to the center of one limiting groove on the first objective table to serve as a liquid taking point, the installation position of the first objective table in the fume hood can be adjusted by rotating a certain angle around the liquid taking point as required, and the adaptability of the equipment is strong;
(5) the utility model discloses still be provided with wiper mechanism for liquid mechanism and connect between the liquid mechanism, when the solution that needs to shift changes, can wash the pipette through wiper mechanism, need not frequently to change and once only move the suction head, reduce use cost.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a top view of the present invention;
fig. 2 is a front view of the present invention;
FIG. 3 is a schematic view of the connection relationship between the first base and the rotary table of the present invention;
FIG. 4 is a side view of the pipetting mechanism of the present invention;
fig. 5 is a front view of the pipetting assembly of the present invention;
FIG. 6 is a schematic view of the internal structure of the liquid feeding mechanism of the present invention;
fig. 7 is a top view of the liquid feeding mechanism of the present invention;
FIG. 8 is a cross-sectional view A-A of the first stage of FIG. 7;
fig. 9 is a top view of the third driving mechanism and the second stage of the present invention;
fig. 10 is a front view of the third driving mechanism and the second stage of the present invention;
fig. 11 is a side view of a third driving mechanism and a second stage according to the present invention;
FIG. 12 is a top view of the cleaning mechanism of the present invention;
FIG. 13 is a schematic view of the internal structure of the cleaning cylinder of the present invention;
reference numerals: 1-liquid feeding mechanism, 11-first base, 12-first driving mechanism, 121-driving gear, 13-first object stage, 131-bearing stage, 132-thrust bearing, 133-accommodating cavity, 134-heat dissipation through hole, 14-gear ring, 15-limit groove, 151-strip groove, 16-positioning buckle, 161-chassis, 162-elastic sheet, 17-fixing bolt, 18-abdicating groove, 19-retainer ring,
2-a liquid-transfering mechanism, 21-a second base, 22-a first mounting frame, 221-a rotating table, 222-a connecting rod, 223-a mounting plate, 224-a first bearing, 225-a second bearing, 23-a second driving mechanism, 24-an air pump, 25-a first belt pulley, 26-a second belt pulley,
3-pipetting assembly, 31-pipette, 32-level sensor, 33-lifting mechanism, 331-support, 332-first drive motor, 333-first drive screw rod, 334-slide rod, 335-connecting piece,
4-liquid receiving mechanism, 41-third driving mechanism, 411-second mounting frame, 412-second transmission screw rod, 413-first guide shaft, 414-second driving motor, 415-guide through hole, 416-second screw through hole, 42-fourth driving mechanism, 421-third mounting frame, 422-third transmission screw rod, 423-second guide shaft, 424-third driving motor, 43-second object stage, 431-first connecting sleeve, 432-second connecting sleeve,
5-cleaning mechanism, 51-cleaning cylinder, 52-water inlet pipe, 53-water outlet pipe, 54-first electromagnetic valve, 55-second electromagnetic valve, 56-speed reducing screw and 6-bottom plate.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
The present embodiment provides an automatic liquid-transfering device, as shown in fig. 1 and fig. 2, which includes a liquid-feeding mechanism 1, a liquid-transfering mechanism 2, a liquid-receiving mechanism 4, a washing mechanism 5, a control mechanism, and a bottom plate 6, wherein the liquid-feeding mechanism 1, the liquid-transfering mechanism 2, the liquid-receiving mechanism 4, and the washing mechanism 5 are all fixedly mounted on the bottom plate 6, and after the device is mounted in a fume hood, one side of the washing mechanism 4 close to the bottom plate 6 is close to an opening of the fume hood.
Specifically, referring to fig. 6 and 7, in the present embodiment, the first base 11 is provided with an annular bearing platform 131, the bearing platform 131 is disposed corresponding to the first object stage 13, and the bottom of the first object stage 13 is rotatably connected to the top of the bearing platform 131 through a thrust bearing 132, so that a larger pressure can be borne between the first object stage 13 and the bearing platform 131, and a user can press and fix the solution container on the first object stage 13 conveniently. The first driving mechanism 12 is a motor, a rotating shaft of the first driving mechanism 12 is provided with a driving gear 121, the middle part of the first base 11 is provided with an accommodating cavity 133, and a machine body of the first driving mechanism 12 is fixedly arranged in the accommodating cavity 133; a gear ring 14 is arranged between the first object stage 13 and the thrust bearing 132, the gear ring 14 is fixedly connected with the first object stage 13, and the driving gear 121 is meshed with the inner side of the gear ring 14. In addition, still be equipped with retaining ring 19 on first base 11, retaining ring 19 encircles and locates between bearing platform 131 and first objective table 13, and retaining ring 19 can carry on spacingly to first objective table 13 periphery, improves equipment structural strength, avoids article or people to block between bearing platform 131 and first objective table 13 simultaneously, improves the security. A heat dissipating through hole 134 is further formed at the center of the bottom of the first stage 13, and the heat generated by the first driving mechanism 12 is dissipated through the heat dissipating through hole 134. In order to avoid that the operator is injured by the transmission mechanism under the first stage 13, the heat dissipation through hole 134 is reduced smaller than the inner diameter of the gear ring 14.
In order to avoid displacement of solution containers such as beakers placed on the first object stage 13 in the rotating process of the first object stage 13, the first object stage 13 is provided with a limiting groove 15, the limiting grooves 15 are uniformly distributed along the circumferential direction of the first object stage 13, and the containers are placed in the limiting groove 15. The first driving mechanism 12 rotates to drive the first object stage 13 to rotate by the same angle each time, and the angle is a central angle of a central connecting line between two adjacent limiting grooves 15 and the first object stage 13. Further, a positioning buckle 16 is arranged in the limiting groove 15, referring to fig. 8, the positioning buckle 16 includes a chassis 161 and an elastic sheet 162, a yielding groove 18 is arranged in the middle of the chassis 161, the chassis 161 is fixedly connected with the bottom of the limiting groove 15 through a fixing bolt 17, and a nut of the fixing bolt 17 is located in the yielding groove 18. The elastic sheet 162 is S-shaped, the fixed end of the elastic sheet 162 is fixedly connected with the chassis 161, the free end of the elastic sheet 162 extends out of the limiting groove 15, the four elastic sheets 162 are uniformly arranged along the circumferential direction of the chassis 161, the upper part of the elastic sheet 162 protrudes towards the center of the limiting groove 15, and the lower end protruding part of the elastic sheet 162 extends into the strip-shaped groove 151 on the circumferential wall of the limiting groove 15. The elastic sheet 162 is made of metal, the elastic sheet 162 has certain elasticity, when a container such as a beaker and a conical flask is placed, the bottom of the container is obliquely clamped between the elastic sheets 162, then the top of the container is slightly pressed for righting, and finally the bottom of the container is in contact with the upper surface of the base plate 161. Set up behind the location buckle 16 can make the container of different diameters both can fix stably in spacing groove 15, the central axis of different diameter containers is collinear with the central axis of spacing groove 15 all the time moreover, is convenient for pipette 31 accurate alignment solution container.
The liquid transferring mechanism 2 comprises a second base 21, a first mounting frame 22, a second driving mechanism 23 and an air pump 24, the second base 21 is fixedly arranged, the first mounting frame 22 is rotatably connected with the second base 21, the first mounting frame 22 is in transmission connection with a power output end of the second driving mechanism 23, the first mounting frame 22 rotates around the central axis of the second base 21 under the driving of the second driving mechanism 23, the electric wire rotating along with the first mounting frame 22 is electrically connected with the fixedly arranged electric wire through an electric brush, and the air pump 24 is fixedly arranged on the first mounting frame 22. Two liquid transfer assemblies 3 are symmetrically arranged on the first mounting frame 22, each liquid transfer assembly 3 comprises a pipette 31, a liquid level sensor 32 and a lifting mechanism 33, each lifting mechanism 33 is fixedly connected with the first mounting frame 22, the pipette 31 is in transmission connection with the power output end of the lifting mechanism 33, and the pipette 31 is driven by the lifting mechanism 33 to move linearly in the vertical direction, namely to be close to or far away from the bottom plate 6. The pipette 31 usually performs liquid taking at a fixed position close to the liquid feeding mechanism 1, and this position is a liquid taking point, and a point symmetrical with respect to the second base 21 is a liquid discharging point, and the liquid discharging point is located close to the liquid receiving mechanism 4. The high-level end of the pipette 31 is communicated with a vent of the air pump 24, the air pump 24 inflates or exhausts air into the pipette 31 to realize the entry or the exit of the solution into or out of the pipette 31, and the liquid level sensor 32 is used for measuring the height of the solution in the pipette 31.
Specifically, as shown in fig. 3 and 4, the second base 21 is cylindrical, the first mounting bracket 22 includes a rotating platform 221, a connecting rod 222 and an annular mounting plate 223, the rotating platform 221 is a cylindrical structure with an open bottom, the rotating platform 221 is fixedly connected with the mounting plate 223 through the connecting rod 222, and the central axis of the rotating platform 221 is collinear with the central axis of the mounting plate 223; the rotating platform 221 is sleeved on the top of the second base 21, a first bearing 224 is disposed between the peripheral wall of the second base 21 and the peripheral wall of the rotating platform 221, and a second bearing 225 is disposed between the top of the second base 21 and the bottom of the rotating platform 221. The first bearing 224 is a radial bearing, the second bearing 225 is a thrust bearing, and the rotation of the rotation stage 221 is stabilized by the first bearing 224 and the second bearing 225.
The second driving mechanism 23 and the rotating platform 221 can be realized by adopting the existing transmission structures such as gears and belts, in this embodiment, the second driving mechanism 23 is realized by adopting a high-precision servo motor, the body of the second driving mechanism 23 is fixed on the peripheral wall of the second base 21, the rotating shaft of the second driving mechanism 23 is provided with a first belt pulley 25, the rotating platform 221 is provided with a second belt pulley 26, and the second driving mechanism 23 drives the rotating platform 221 to rotate around the central axis of the second base 21 through the transmission belt, so that the position of the pipette 31 can be accurately controlled.
Referring to fig. 5, the lifting mechanism 33 includes a bracket 331, a first driving motor 332, a first transmission screw 333 and a sliding rod 334; the machine bodies of the support 331 and the first driving motor 332 are fixedly connected with the first mounting frame 22, the first transmission screw 333 is rotatably connected with the support 331, the first transmission screw 333 is in transmission connection with a rotating shaft of the first driving motor 332 through a transmission belt, and the first transmission screw 333 is driven by the first driving motor 332 to rotate around the central axis of the first transmission screw; a limiting through hole (not shown in the figure) is formed in the support 331, the sliding rod 334 penetrates through the limiting through hole and is arranged in parallel with the first transmission screw rod 333, a connecting piece 335 is fixedly arranged in the middle of the sliding rod 334, a first threaded through hole (not shown in the figure) matched with the first transmission screw rod 333 is formed in the connecting piece 335, and the first transmission screw rod 333 penetrates through the first threaded through hole; the high end of the pipette 31 is fixedly connected to the low end of the sliding rod 334, and the pipette 31 is parallel to the sliding rod 334. The first screw 333 rotates to drive the connecting member 335 and the sliding rod 334 to slide along the length direction of the first screw 333, and further drive the pipette 31 to move up and down. Further, the liquid level sensor 32 is an ultrasonic liquid level sensor, and the ultrasonic liquid level sensor is fixedly arranged on the top of the pipette 31.
The liquid receiving mechanism 4 comprises a third driving mechanism 41, a fourth driving mechanism 42 and a second objective table 43, a limiting protrusion for limiting is arranged at the top of the second objective table 43, the second objective table 43 is in transmission connection with a power output end of the third driving mechanism 41, the second objective table 43 is driven by the third driving mechanism 41 to move linearly along a first preset direction, a machine body of the third driving mechanism 41 is in transmission connection with a power output end of the fourth driving mechanism 42, the third driving mechanism 41 and the second objective table 43 are driven by the fourth driving mechanism 42 to move linearly along a second preset direction, the first preset direction is perpendicular to the second preset direction, and a plane where the first preset direction and the second preset direction are located is parallel to the upper surface of the bottom plate 6. After the installation is completed, the first preset direction is parallel to the left and right width direction of the fume hood, and the second preset direction is parallel to the front and back depth direction of the fume hood.
The third driving mechanism 41 and the fourth driving mechanism 42 can be implemented by using an existing structure that can implement linear driving, such as an air cylinder or a lead screw plus a guide shaft, and the position of the second stage 43 can be more accurately controlled by using the lead screw plus the guide shaft. In this embodiment, as shown in fig. 9, 10 and 11, the third driving mechanism 41 includes a second mounting bracket 411, a second driving screw 412, a first guide shaft 413 and a second driving motor 414, a body of the second driving motor 414 and the first guide shaft 413 are both fixedly connected to the second mounting bracket 411, the second driving screw 412 is parallel to the first guide shaft 413, the second driving screw 412 is rotatably connected to the second mounting bracket 411, the second driving screw 412 is in transmission connection with a rotating shaft of the second driving motor 414 through a transmission belt, and the second driving screw 412 is driven by the second driving motor 414 to rotate around its central axis; the second objective table 43 is located between the first guide shaft 413 and the second transmission screw 412, a first connecting sleeve 431 is arranged in the middle of one side of the second objective table 43 close to the first guide shaft 413, the first connecting sleeve 431 is sleeved on the first guide shaft 413, a second connecting sleeve 432 is arranged in the middle of one side of the second objective table 43 close to the second transmission screw 412, the second transmission screw 412 is sleeved on the second connecting sleeve 432, a thread matched with the second transmission screw 412 is arranged on the inner wall of the second connecting sleeve 432, and the second transmission screw 412 rotates to drive the second objective table 43 to slide along the first guide shaft 413.
As shown in fig. 1, the fourth driving mechanism 42 includes a third mounting frame 421, a third driving screw 422, a second guide shaft 423 and a third driving motor 424, the body of the third driving motor 424 and the second guide shaft 423 are both fixedly connected to the third mounting frame 421, the second guide shaft 423 is perpendicular to the first guide shaft 413, the third driving screw 422 is parallel to the second guide shaft 423, the third driving screw 422 is rotatably connected to the third mounting frame 421, the third driving screw 422 is fixedly connected to a rotating shaft of the third driving motor 424, and the third mounting frame 421 is driven by the third driving motor 424 to rotate around its central axis; the second mounting bracket 411 is provided with a guide through hole 415 matched with the second guide shaft 423 and a second thread through hole 416 matched with the third transmission screw 422, the second guide shaft 423 penetrates through the guide through hole 415, the third transmission screw 422 penetrates through the second thread through hole 416, and the third transmission screw 42 rotates to drive the second mounting bracket 411 to slide along the second guide shaft 423.
The cleaning mechanism 5 is used for cleaning the pipette 31, as shown in fig. 12 and 13, the cleaning mechanism 5 includes a cleaning cylinder 51, a water inlet pipe 52 and a water outlet pipe 53, an opening is formed in the top of the cleaning cylinder 51, the water inlet pipe 52 is communicated with the high-level end of the cleaning cylinder 51, water flows from the water inlet pipe 52 into the cleaning cylinder 51, a first electromagnetic valve 54 is arranged on the water inlet pipe 52, in order to improve the washing capacity of the water flows on the peripheral wall of the pipette 31, the water inlet pipe 52 is tangent to the peripheral wall of the cleaning cylinder 51, and thus the water flows into the cleaning cylinder 51. The water outlet pipe 53 is communicated with the low-level end of the cleaning barrel 51, water flows out of the cleaning barrel 51 from the water outlet pipe 53, and the water outlet pipe 53 is provided with a second electromagnetic valve 55. Further, the inner wall of the washing cylinder 51 is provided with a deceleration screw 56, the deceleration screw 56 is positioned at the upper part of the washing cylinder 51, and the diameter of the central through hole of the deceleration screw 56 is larger than the outer diameter of the pipette 31. When the pipette 31 stretches into the cleaning barrel 51 for cleaning, the speed of the water flow moving downwards in the cleaning barrel 51 can be reduced by arranging the decelerating screw 56, the water flow is promoted to be spirally moved along the peripheral wall of the cleaning tube 31, and the cleaning effect is improved.
It should be noted that the terms describing the orientation such as "up, down, left, right" and the like are relative positional relationships when the equipment is normally operated after being installed, and the positional relationships such as "parallel" and "collinear" between the components are not mathematically absolutely parallel or collinear, and in the case of normal operation of the equipment, it should be allowable to satisfy the misalignment within the error range.
The control mechanism can be realized by adopting the existing equipment which can realize logic control, such as a single chip microcomputer, and the like, in the embodiment, a display screen for displaying data, a keyboard for inputting information and a storage mechanism for storing data are also arranged, and the display screen, the keyboard and the storage mechanism are all purchased for realizing the installation of the existing equipment, which is not shown in the figure. The signal input end of the display screen, the signal input end of the first driving mechanism 12, the signal input end of the second driving mechanism 23, the signal input end of the first driving motor 332 of the lifting mechanism 33, the signal input end of the air pump 24, the signal input end of the second driving motor 414 of the third driving mechanism 41, the signal input end of the third driving motor 424 of the fourth driving mechanism 42, the signal input end of the first electromagnetic valve 54 and the signal input end of the second electromagnetic valve 55 are all connected with the signal output end of the control mechanism, the signal output end of the keyboard and the signal output end of the liquid level sensor 32 are connected with the signal input end of the control mechanism, and the storage mechanism is electrically connected with the control mechanism in a bidirectional mode.
The equipment operates as follows:
placing a container: the experimenter controls the device to enter the receiving container program through the input mechanism, the second object table 43 moves to the position closest to the opening of the fume hood, and then the container to be received is placed on the second object table 43. If the container to be filled is a test tube, the test tube is placed on the second stage 43 together with the test tube rack. Next, the liquid feeding container is placed in the limiting groove 15 closest to the opening position of the fume hood, after the liquid feeding container is placed, the input mechanism controls the first object table 13 to rotate anticlockwise for a certain angle, so that the next limiting groove 15 moves to the position closest to the opening position of the fume hood to receive the container, and finally, the liquid feeding containers are all placed on the first object table 13 according to a certain sequence. After the placement is finished, parameters such as the number of the liquid feeding containers, the number of the liquid receiving containers, the corresponding relation between the liquid feeding containers and the liquid receiving containers in the liquid transferring process, the amount of the solution to be transferred and the like are manually input, and the control mechanism transmits the received information into a built-in control program for control. The built-in program of the device generally marks a test tube positioned on the left upper part of the test tube rack as the initial No. 1 by default, the program in the control mechanism sequentially distinguishes the test tube marks at other positions on the test tube rack according to a certain sequence, and the program in the control mechanism can also sequentially distinguish the marks of the liquid feeding containers.
Liquid transfer operation: the input means sends a signal to the control means to start pipetting. The control mechanism controls the container needing to be supplied with liquid to move to a liquid taking point, meanwhile, the pipette 31 moves right above the liquid supplying point, then the pipette 31 moves downwards for a certain distance along with the sliding rod 334, the lower part of the pipette 31 extends into the solution, then the air pump 24 pumps air in the pipette 31 at a certain speed, the solution gradually enters the pipette 31, the liquid level sensor 32 transmits the detected height information of the solution to the control mechanism in real time, and the control mechanism converts the volume of the solution according to the height of the solution. When the control means judges that the set amount is reached, the control means controls the air pump 24 to stop the exchange of air with the pipette 31. Then the pipette 31 moves upwards, the second driving mechanism 23 drives the pipette 31 to move to the liquid discharge point, and the container to be filled simultaneously moves to the liquid discharge point during the movement of the pipette 31. Next, the pipette 31 moves down a certain distance, and the air pump 24 slowly sends air into the pipette 31 to make the solution in the pipette 31 enter the liquid receiving container. Finally, the pipette 31 moves upwards to be ready to move to the liquid taking point for the next liquid taking operation, and the operation is repeated. The program changes the container for liquid supply by controlling the rotation of the first stage 13, adjusts the container for receiving the solution by controlling the position of the second stage 43, and debugs the apparatus to enable the amount of the transferred solution to achieve high accuracy.
Cleaning operation: when the pipette 31 is to transfer another solution of a different kind or concentration, the device automatically enters a washing procedure. The pipette 31 moves to just above the washing cylinder 51, and then the pipette 31 moves down to be inserted into the washing cylinder 51. The second solenoid valve 55 is closed first, the first solenoid valve 54 is opened, water flows into the washing barrel 51, and the air pump 24 controls the pipette 31 to suck clean water in the washing barrel 51. The same amount of clear water is injected each time, the height of the clear water in the cleaning barrel 51 and the height of the clear water in the pipette 31 reach the upper part of the pipette when the water injection is completed, and the inner and outer cleaning of the pipette 31 is synchronously carried out. Then the second electromagnetic valve 55 is opened, the pipette 31 and the cleaning barrel 51 discharge clean water, then the second electromagnetic valve 55 is closed again, water is injected into the cleaning barrel 51 again, the second cleaning operation is carried out, and the pipette 31 can be cleaned inside and outside by repeating the operation for 3-5 times. If necessary, the pipette 31 may be inserted into the solution supply container to suck the solution and then discharged from the cleaning cylinder 51, thereby performing a rinsing function.
Claims (10)
1. An automatic pipetting device is characterized in that: comprises a liquid feeding mechanism, a liquid transferring mechanism, a liquid receiving mechanism, a cleaning mechanism and a control mechanism;
the liquid feeding mechanism comprises a first base, a first driving mechanism and a circular first object stage, the first base is fixedly arranged, the first object stage is rotatably connected with the first base, the first object stage is in transmission connection with a power output end of the first driving mechanism, and the first object stage is driven by the first driving mechanism to rotate around the central axis of the first object stage;
the liquid transfer mechanism comprises a second base, a first mounting frame, a second driving mechanism and an air pump, the second base is fixedly arranged, the first mounting frame is rotatably connected with the second base, the first mounting frame is in transmission connection with a power output end of the second driving mechanism, the first mounting frame is driven by the second driving mechanism to rotate around the central axis of the second base, and the air pump is fixedly arranged on the first mounting frame; the first mounting frame is symmetrically provided with a plurality of liquid transfer assemblies, each liquid transfer assembly comprises a pipette, a liquid level sensor and a lifting mechanism, the lifting mechanism is fixedly connected with the first mounting frame, the pipette is in transmission connection with the power output end of the lifting mechanism, the pipette is driven by the lifting mechanism to do linear motion in the vertical direction, the high-level end of the pipette is communicated with the air vent of the air pump, and the liquid level sensors are used for measuring the height of the solution in the pipette;
the liquid receiving mechanism comprises a third driving mechanism, a fourth driving mechanism and a second objective table, the second objective table is in transmission connection with a power output end of the third driving mechanism, the second objective table is driven by the third driving mechanism to perform linear motion along a first preset direction, a machine body of the third driving mechanism is in transmission connection with a power output end of the fourth driving mechanism, the third driving mechanism and the second objective table are driven by the fourth driving mechanism to perform linear motion along a second preset direction, and the first preset direction is perpendicular to the second preset direction;
the cleaning mechanism is used for cleaning the pipette, the cleaning mechanism comprises a cleaning barrel, a water inlet pipe and a water outlet pipe, an opening is formed in the top of the cleaning barrel, the water inlet pipe is communicated with the high-position end of the cleaning barrel, a first electromagnetic valve is arranged on the water inlet pipe, the water outlet pipe is communicated with the low-position end of the cleaning barrel, and a second electromagnetic valve is arranged on the water outlet pipe;
the liquid feeding mechanism, the liquid receiving mechanism and the cleaning mechanism are all positioned below the liquid transferring assembly, when one pipette moves to the position right above the first objective table, the other pipette is positioned right above the second objective table;
the signal input end of the first driving mechanism, the signal input end of the second driving mechanism, the signal input end of the lifting mechanism, the signal input end of the air pump, the signal input end of the third driving mechanism, the signal input end of the fourth driving mechanism, the signal input end of the first electromagnetic valve and the signal input end of the second electromagnetic valve are all connected with the signal output end of the control mechanism, and the signal output end of the liquid level sensor is connected with the signal input end of the control mechanism.
2. The automatic pipetting apparatus of claim 1, wherein: the first base is provided with an annular bearing platform, the bearing platform corresponds to the first object stage, and the bottom of the first object stage is rotatably connected with the top of the bearing platform through a thrust bearing.
3. The automatic pipetting apparatus of claim 2, wherein: the first driving mechanism is a motor, a rotating shaft of the first driving mechanism is provided with a driving gear, the middle part of the first base is provided with an accommodating cavity, and a machine body of the first driving mechanism is fixedly arranged in the accommodating cavity; first objective table with be equipped with the gear circle between the thrust bearing, the gear circle with first objective table fixed connection, drive gear with the inboard meshing of gear circle.
4. Automatic pipetting device according to claim 1 or 2 or 3, characterized in that: the first object stage is provided with a limiting groove, the limiting grooves are uniformly distributed along the circumferential direction of the first object stage, and a positioning buckle is arranged in each limiting groove; the positioning buckle comprises a chassis and elastic pieces, the chassis is fixedly connected with the bottom of the limiting groove, the elastic pieces are S-shaped, the fixed ends of the elastic pieces are fixedly connected with the chassis, the free ends of the elastic pieces extend out of the limiting groove, and the elastic pieces are uniformly arranged along the circumferential direction of the chassis.
5. The automatic pipetting apparatus of claim 1, wherein: the second base is cylindrical, the first mounting frame comprises a rotating table, a connecting rod and an annular mounting plate, the rotating table is of a cylindrical structure with an opening at the bottom, the rotating table is fixedly connected with the mounting plate through the connecting rod, and the central axis of the rotating table is collinear with the central axis of the mounting plate; the rotating platform is sleeved at the top of the second base, a first bearing is arranged between the peripheral wall of the second base and the peripheral wall of the rotating platform, and a second bearing is arranged between the top of the second base and the bottom of the rotating platform.
6. The automatic pipetting apparatus of claim 1, wherein: the lifting mechanism comprises a bracket, a first driving motor, a first transmission screw rod and a sliding rod; the support and the body of the first driving motor are fixedly connected with the first mounting frame, the first transmission screw rod is rotatably connected with the support, the first transmission screw rod is in transmission connection with a rotating shaft of the first driving motor, and the first transmission screw rod is driven by the first driving motor to rotate around the central axis of the first transmission screw rod; the bracket is provided with a limiting through hole, the sliding rod penetrates through the limiting through hole and is arranged in parallel with the first transmission screw rod, the middle part of the sliding rod is fixedly provided with a connecting piece, the connecting piece is provided with a first thread through hole matched with the first transmission screw rod, and the first transmission screw rod penetrates through the first thread through hole; the high-position end of the pipette is fixedly connected with the low-position end of the sliding rod, and the pipette is parallel to the sliding rod.
7. The automatic pipetting apparatus of claim 6, wherein: the liquid level sensor is an ultrasonic liquid level sensor which is fixedly arranged at the top of the pipette.
8. The automatic pipetting apparatus of claim 1, wherein: the third driving mechanism comprises a second mounting frame, a second transmission screw rod, a first guide shaft and a second driving motor, a machine body of the second driving motor and the first guide shaft are fixedly connected with the second mounting frame, the second transmission screw rod is parallel to the first guide shaft, the second transmission screw rod is rotatably connected with the second mounting frame, the second transmission screw rod is in transmission connection with a rotating shaft of the second driving motor, and the second transmission screw rod is driven by the second driving motor to rotate around the central axis of the second transmission screw rod; the second objective table is located first guiding axle with between the second transmission lead screw, the second objective table is close to one side middle part of first guiding axle is equipped with first connecting sleeve, first connecting sleeve cover is located first guiding axle, the second objective table is close to one side middle part of second transmission lead screw is equipped with the second connecting sleeve, the second connecting sleeve cover is located the second transmission lead screw, the inner wall of second connecting sleeve be equipped with second transmission lead screw matched with screw thread.
9. The automatic pipetting apparatus of claim 8, wherein: the fourth driving mechanism comprises a third mounting frame, a third transmission screw rod, a second guide shaft and a third driving motor, wherein a machine body of the third driving motor and the second guide shaft are fixedly connected with the third mounting frame, the second guide shaft is perpendicular to the first guide shaft, the third transmission screw rod is parallel to the second guide shaft, the third transmission screw rod is rotatably connected with the third mounting frame, the third transmission screw rod is in transmission connection with a rotating shaft of the third driving motor, and the third mounting frame is driven by the third driving motor to rotate around the central axis of the third mounting frame; the second mounting bracket is provided with a guide through hole matched with the second guide shaft and a second thread through hole matched with the third transmission screw rod, the second guide shaft penetrates through the guide through hole, and the third transmission screw rod penetrates through the second thread through hole.
10. The automatic pipetting apparatus of claim 1, wherein: the inner wall of the cleaning barrel is provided with a speed reduction screw, and the speed reduction screw is positioned at the upper part of the cleaning barrel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921695267.1U CN211051534U (en) | 2019-10-11 | 2019-10-11 | Automatic liquid transfer equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921695267.1U CN211051534U (en) | 2019-10-11 | 2019-10-11 | Automatic liquid transfer equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211051534U true CN211051534U (en) | 2020-07-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921695267.1U Expired - Fee Related CN211051534U (en) | 2019-10-11 | 2019-10-11 | Automatic liquid transfer equipment |
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| Country | Link |
|---|---|
| CN (1) | CN211051534U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359523A (en) * | 2023-05-30 | 2023-06-30 | 深圳市第二人民医院(深圳市转化医学研究院) | Medical automatic sample split charging instrument and system |
-
2019
- 2019-10-11 CN CN201921695267.1U patent/CN211051534U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359523A (en) * | 2023-05-30 | 2023-06-30 | 深圳市第二人民医院(深圳市转化医学研究院) | Medical automatic sample split charging instrument and system |
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Granted publication date: 20200721 Termination date: 20211011 |